Type I Bicuspid Aortic Valve Sparing Root Reimplantation 180°/180° vs. 150°/210° Orientation Prashanth Vallabhajosyula, MD MS Division of Cardiovascular Surgery University of Pennsylvania Disclosures None Talk outline Discussion points: • Heterogeneity of type I BAV • Decision making during intraoperative evaluation • Technical aspects of geometric orientation of the aortic neoroot • Institutional outcomes Will not be discussing: • Primary leaflet repair techniques • Billowing concept BAV type 0 vs type 1 Type 0 Type I 105 105 150 180 Type 0 (true) Type 0 Pictures courtesy of G. El‐Khoury Type 1 (Sievers et al. JTCVS 2007) 180 Type 1 BAV VSRR: Neoroot Orientation determined at the annulus affects commissure fixation and free margin What time during surgery do we make the decision regarding neoroot leaflet configuration? Type 1 BAV evaluation and free margin equalization Post-repair evaluation Perimeter assessment This is when we make a decision about the neoroot orientation Technical aspects of neoroot orientation • Preparation for root reimplantation • Subannular suture placement: orienting the annulus perimeter in the neoroot • Fixing the desired leaflet configuration • Completion of the reimplantation procedure 150°/105°/105° orientation 180°/180° orientation Institutional outcomes Demographics and preoperative parameters BAV 210°/150° BAV 180°/180° N 24 21 Age, yrs 43 ± 12 48 ± 11 0.2 Male 21:3 19:2 1.0 Hypertension 11 (46%) 10 (48%) 1.0 Diabetes 4 (16%) 1 (5%) 0.4 Smoker 8 (33%) 7 (33%) 1.0 Ejection fraction, % 59 ± 10 57 ± 7 0.5 LV diastolic diameter, mm 59 ± 10 54 ± 8 0.1 LV systolic diameter, mm 37 ± 7 36 ± 8 0.8 Annulus, mm 30 ± 4 30 ± 4 0.9 Sinotubular junction, mm 45 ± 6 43 ± 6 0.4 Sinus of valsalva, mm 49 ± 5 48 ± 7 0.7 Ascending aorta, mm 46 ± 9 47 ± 9 0.5 0 3 (12%) 0 0.2 1 4 (17%) 1 (5%) 0.4 2 7 (29%) 8 (38%) 0.5 3 4 (17%) 3 (15%) 1.0 4 6 (25%) 9 (43%) 0.2 p Preoperative Aortic Insufficiency Intraoperative and postoperative outcomes BAV 210°/150° BAV 180°/180° N 24 21 Cardiopulmonary bypass (CPB), min 295 ± 50 286 ± 56 0.2 Cross clamp, min 240 ± 54 237 ± 45 0.8 Circulatory arrest, min 20 ± 5 17 ± 5 0.1 Arch replacement (%) 17 (71%) 15 (71%) 1.0 MV Repair (%) 0 0 1.0 CABG (%) 1 (4%) 0 1.0 Stroke (%) 0 0 1.0 Reoperation for bleeding (%) 0 0 1.0 Pacemaker placement (%) 0 0 1.0 Mortality (%) 0 1 0.5 No Differences p Repair techniques and discharge echo BAV 210°/150° BAV 180°/180° 24 21 Primary leaflet repair Raphe release 24 (100%) 18 (75%) 21 (100%) 11 (52%) 1.0 0.1 Resection with primary closure 4 (16%) 2 (8%) 18 (75%) 6 (25%) 0 5 (12%) 1 (5%) 1 (5%) 16 (76%) 3 (14%) 0 3 (3%) 0.4 BAV 210°/150° BAV 180°/180° N 24 21 Freedom from AI >1+ 40 (100%) 21 (100%) 1.0 Peak gradient (mmHg) 11 ± 6 12 ± 5 0.5 Mean gradient (mmHg) 6 ± 3 6 ± 4 1.0 Leaflet Coaptation (mm) 9 ± 2 9 ± 2 1.0 N Goretex free margin shortening Leaflet plication Leaflet decalcification Patch repair Fenestration repair p 1.0 1.0 0.5 1.0 0.7 p Same Freedom from AI>1+ Summary • Orienting the neoroot in BAV type 1 VSRR based on the amount of annular circumference occupied by each leaflet is a reasonable and safe approach • Application of this concept may help minimize billowing, and facilitate a more “natural” leaflet configuration in the neoroot • Long term clinical and echocardiographic followup with larger series will be needed to understand the validity of this concept Acknowledgements Caroline Komlo Kei Wildendorp Thank you
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