GAMBLING AND PUBLIC HEALTH IN GREENLAND – A LARGE INDIGENOUS POPULATION IN TRANSITION A study of gambling behavior and problem gambling in relation to social transition, addictive behaviors and health among Greenland Inuit. PhD Thesis Christina Viskum Lytken Larsen Centre for Health Research in Greenland January 2014 PhD Thesis Centre for Health Research in Greenland, National Institute of Public Health, Faculty of Health Science, University of Southern Denmark GAMBLING AND PUBLIC HEALTH IN GREENLAND – A LARGE INDIGENOUS POPULATION IN TRANSITION A study of gambling behavior and problem gambling in relation to social transition, addictive behaviors and health among Greenland Inuit. Christina Viskum Lytken Larsen January 2014 3 ACKNOWLEDGEMENTS Without question I am indebted to my husband Malik (I have no words!), my daughter Selma and the twins (at the time still unborn) who supported me through a busy summer and fall of 2012 and all the other busy times... This goes for my closest family as well: My brothers, Thomas and Søren, and their very cool women, Eva and Nikoline, for moral support, baby sitting and good fun. My parents, Mogens and Marianne, for intellectual support, lots of love and heroic visits during the last months before deadline, which included fun times for Selma, emptying the dish washer again and again, doing laundry and tidying up (no need to end these visits by the way…). Also, I would like to thank: • • • • Cecilia, Inger, Sus, Charlotte, Anni, Marit, Isabelle and Ingelise at the Center for Health Research in Greenland. For fun times, support and great discussions. My colleagues at the Institute for Nursing and Health Science, University of Greenland, and my former colleagues at the Department of Social Work (ISI), University of Greenland, for teaching me about health and people in Greenland even before I came into the research business. The students I had the pleasure to meet at the University of Greenland. I am sure they have taught me more, than I could actually teach them. The people at the National Institute of Public Health for an inspiring working environment and many relevant discussions. I owe a special thanks to my supervisors, Professor Peter Bjerregaard and PhD Tine Curtis, who have guided me through many analyses, discussions and methodological considerations during these years. It has been an inspiring learning process and I look forward to continue our discussions in the future. Finally I would like to dedicate this thesis to my beloved and respected grandfather Poul Viskum, a pioneering medical doctor in his field, who passed away while I was finishing my PhD studies. Among the many inspiring accomplishments of my grandfather, were medical visits to towns in Midwest Greenland during the 1950s with the Danish ship Heimdal. These visits were the foundation of many important discussions along with all the other great discussions we have had during the past 30 years. I will miss you! 4 Outline of thesis Paper I: Larsen CVL, Curtis T, Bjerregaard P. Gambling behavior and problem gambling reflecting social transition and traumatic childhood events among Greenland Inuit - a cross-sectional study in a large indigenous population undergoing rapid change; Journal of Gambling Studies, 2013, 29 (4): 73348. Paper II: Larsen CVL, Curtis T, Bjerregaard P. Harmful alcohol use and frequent use of marijuana among lifetime problem gamblers and the prevalence of cross-addictive behaviors among Greenland Inuit – evidence from the cross-sectional Inuit Health in Transition Greenland Survey 2006-2010; International Journal of Circumpolar Health, 2013, 72:19551. doi: 10.3402/ijch.v72i0.19551. Paper III: Larsen CVL, Curtis T, Bjerregaard P. Health status and health behavior associated with frequent gambling and problem gambling in a large indigenous population – A cross-sectional study based on The Inuit Health in Transition Greenland Survey 2006-2010. Article in review November 2013 Academic supervisors: Professor Peter Bjerregaard, MD, DMSs. Centre for Health Research in Greenland, National Institute of Public Health, University of Southern Denmark. Professor Tine Curtis, PhD, MA Sociology. Local Government Denmark and National Institute of Public Health, University of Southern Denmark. 5 List of abbreviations BBGS Brief Biosocial Gambling Screen CI Confidence Interval DSM-III Third edition of the Diagnostic and Statistical Manual DSM-III-R Third revised edition of the Diagnostic and Statistical Manual DSM-IV Fourth edition of the Diagnostic and Statistical Manual DSM-IV-R Fourth revised edition of the Diagnostic and Statistical Manual DSM-V Fifth edition of the Diagnostic and Statistical Manual ICD-9 WHO’s ninth edition of the International Classification of Diseases ICD-10 WHO’s tenth edition of the International Classification of Diseases IHIT Inuit Health in Transition Study NODS National Opinion Research Center DSM-IV Screen for Gambling Problems NODS CLiP Short version of National Opinion Research Center DSM-IV Screen OR Odds ratio SOGS-R Revised South Oaks Gambling Screen 6 Contents ACKNOWLEDGEMENTS ........................................................................................................................... 4 Outline of thesis ...................................................................................................................................... 5 List of abbreviations ................................................................................................................................ 6 1. INTRODUCTION ................................................................................................................................... 9 1.1 Objective ..................................................................................................................................... 10 2. Background........................................................................................................................................ 11 2.1 Concepts and definitions ............................................................................................................. 11 Gambling activities and gambling behavior. ................................................................................. 11 Pathological gambling – a definition ............................................................................................. 12 Problem gambling – widening the concept of pathological gambling .......................................... 13 2.2 Towards a public health perspective on gambling ...................................................................... 14 2.3 The role of gambling and problem gambling in a population undergoing social transition ....... 15 3. MATERIAL AND METHODS ................................................................................................................ 19 3.1 Inuit health in transition across the Arctic .................................................................................. 19 3.2 Sample and participation ............................................................................................................ 21 3.3 Data Collection ............................................................................................................................ 24 3.4 Outcomes and exposures ............................................................................................................ 24 Past year gambling behavior ......................................................................................................... 24 Past year and lifetime problem gambling ..................................................................................... 25 Sociodemographic variables.......................................................................................................... 27 Social transition ............................................................................................................................. 27 Traumatic events during childhood............................................................................................... 28 Addictive behaviors ....................................................................................................................... 28 Health status ................................................................................................................................. 29 Health behavior ............................................................................................................................. 29 3.5 Data analysis and statistical methods ......................................................................................... 30 3.6 Validity and completeness of data source .................................................................................. 30 3.7 Ethical considerations ................................................................................................................. 31 4. RESULTS ............................................................................................................................................. 33 4.1 Overview of results...................................................................................................................... 33 4.2 Paper I.......................................................................................................................................... 33 4.3 Paper II......................................................................................................................................... 34 7 4.4 Paper III........................................................................................................................................ 35 5. DISCUSSION ....................................................................................................................................... 37 5.1 Main findings ............................................................................................................................... 37 Main findings in perspective to other studies............................................................................... 37 5.2 Methodological considerations ................................................................................................... 37 Selection bias................................................................................................................................. 37 Information bias ............................................................................................................................ 38 Confounding and intermediate factors ......................................................................................... 40 Type-I and type II-errors ................................................................................................................ 41 Lessons to learn about measuring problem gambling .................................................................. 41 5.3 Understanding the nature of problem gambling ........................................................................ 42 5.4 Problem gambling in the light of the ongoing social transition .................................................. 44 6. CONCLUSION ..................................................................................................................................... 47 7. IMPLICATIONS ................................................................................................................................... 49 7.1 For research................................................................................................................................. 49 7.2 For public health.......................................................................................................................... 50 8. SUMMARY ......................................................................................................................................... 51 9. RESUMÉ ............................................................................................................................................. 52 10. EQIKKAANEQ ................................................................................................................................... 53 11. REFERENCES .................................................................................................................................... 55 APPENDIX 1 ........................................................................................................................................... 63 APPENDIX 2 ........................................................................................................................................... 67 APPENDIX 3 ........................................................................................................................................... 71 PAPERS I-III ............................................................................................................................................ 73 8 1. INTRODUCTION During recent years gambling in general and pathological gambling in particular has become a much debated subject in Greenland. The economic and social problems for individuals, families and communities which extensive gambling can lead to are of great concern. At the start of the project, knowledge in the field was limited to a countrywide telephone survey and a qualitative survey conducted by the Department of Health in Greenland (Paarisa) in 2005 among local public health coordinators and more knowledge was needed (1). The health coordinators had pointed out extensive gambling on bingo and card games as the biggest gambling related problem in the Greenlandic communities and especially bingo was suspected to lead to the neglect of children because it is often played both during the day and during the evening, where children need their parents’ attention (1). The yearly revenue from gambling products sold in Greenland at Danske Spil who controls the lotteries in Greenland and Denmark – had increased with 50% from DKK 47.8 to DKK 71.6 million in the years 1999-2007, indicating an increase in gambling activities. In addition to this, the revenue from gambling on the privately owned slot machines was estimated to be DKK 80.3 million in 2004 alone (1). The revenue from bingo and gambling on cards and dice in private settings are unknown. An increase in gambling activities and the concern for pathological gambling is by no means limited to the Greenlandic context, but a much more global concern following the expansion of gambling opportunities online and liberalization of the gambling legislation seen in many western countries these years. However indigenous populations and ethnic minorities are considered to be especially vulnerable to gambling problems based on a higher prevalence of pathological gambling among these groups compared to the general populations within the same regions (2-5), but little is known of why it is so. Following Shaffer et al. “the study of incidence among vulnerable and resilient populations is a road yet to be taken” (4), p. 504. This is also a road where determinants of gambling problems should be studied more carefully. It is likely that the marginalization many of these populations experience in regions with other majority populations is a part of the explanation. In Greenland, Inuit constitute the majority of the population and the present study therefore provides a unique opportunity to investigate problem gambling in a large indigenous population, that is a majority in own country. An increase in social pathologies such as violence, suicide, alcohol and substance use is a key feature shared by indigenous populations in the circumpolar region undergoing social transition (6;7). In Greenland, the high proportion of the adult population who experienced alcohol problems in their childhood home and a similar high prevalence of persons who were sexually abused as children are examples of such pathologies. An overall motivation for the study was thus to investigate, if pathological gambling should be added to this list of social pathologies among Inuit in Greenland, through a research based understanding of the role of gambling and gambling problems in Greenland today in the light of the ongoing social transition. 9 1.1 Objective The objective of the thesis was to investigate the prevalence of gambling behavior and problem gambling in a representative sample of Greenland Inuit and its association with social transition, addictive behaviors and health. The overall objective was investigated based on three research questions answered in Paper I-III: I. II. III. How prevalent are different types of gambling and problem gambling among Inuit in Greenland and how is gambling behavior and problem gambling associated with social transition and traumatic events during childhood? [PAPER I] How is lifetime problem gambling associated with harmful alcohol use and frequent use of marijuana and does the association vary according to sociodemographic characteristics? [PAPER II] How is health status and health behavior associated with different types of frequent gambling and lifetime problem gambling? [PAPER III] 10 2. Background 2.1 Concepts and definitions Gambling activities and gambling behavior. Gambling is a common leisure activity in most of the world and can be traced far back in history to archaeologists’ uncovering of primitive dice found in caves dating back to 3500 BCE (8). Gambling opportunities are available on the internet, television, radio, in casinos, in bars, diners and various gambling venues. You can gamble at home or you can go out and gamble. Gambling activity naturally presupposes gambling opportunities, and most studies have found a significant association between access and availability of gambling on one hand, and the prevalence of gambling on the other. Typically the introduction of new gambling opportunities such as the opening of a casino will lead to an increase in gambling activities, but there is also evidence, that some form of adaptation can take place over time and the prevalence will stabilize (8;9). In the studies for Papers I-III, the term gambling activities refer to different types of available gambling opportunities such as the lotteries and bingo. Gambling behavior refers to the type of gambling activities people engage in and how often they gamble. There is no historic documentation of gambling in Greenland and the possible existence and role of gambling among Inuit back in time is therefore unknown (1). Most gambling activities present in Greenland today have been adopted from the Danish gambling market and thus resemble gambling opportunities in Denmark and more generally Scandinavia. Common gambling activities in Greenland are the lottery, bingo, slot machines/electronic gaming machines (EGMs) and card/dice games. The lottery is a general term for several different types of games such as lotto, scratch tickets, betting on sports and other numbers and knowledge games all controlled by the national lottery in Denmark, Danske Spil. The lottery is available at the local stores in all towns and in some villages. In addition lottery gambling from Danske Spil is available online. Gambling on the lottery is regulated by Danish law, but Greenlandic law applies to the distribution of a proportion of the revenue from the products sold by Danske Spil in Greenland (10). Some of which are spent on sports, youth and cultural activities. Bingo is played all over Greenland both over the radio and in local community halls and sports centers. Most bingo games are organized by local radio stations and local associations for which the revenue serves as the primary source of income. It is also common for parents to organize bingo games to raise money for their children’s school trips and excursions. The amount of organized bingo games varies from place to place. In most towns and villages bingo is available on a daily basis. In some places bingo is played several times a day given the availability over different local radio stations in the area in addition to games held in the local halls and sports centers. Only public bingo games require permission from the police. Bingo games arranged by the local associations for members are not registered. A taxation of the winnings is required by law (11). Slot machines are located at the bars and grills, but in towns only. No permissions for slot machines have been granted to villages by the municipal councils. The slot machines are owned by private investors and generate a yearly revenue of up to 1 million DKK (1). The revenues from slot machines serve as a main source of income for the local bars and grills. Taxation is regulated by law (12;13). 11 Gambling on cards/dice represent a grey area since gambling on these types of games is prohibited by law. Cards and dice games presumably take place in private settings, but no official records document the extent of gambling in this area due to its illegal status. Despite the lack of documentation, it is well known within Greenland that card games are played extensively on the East coast, where the traditional social gatherings ‘Kaffemik’ are often turned into gambling tournaments, when coffee and cake has been consumed. People can engage in gambling in very different ways and the role of gambling can vary significantly between communities. Gambling on the lottery can be limited to buying a scratch ticket once in a while or a weekly lotto coupon, when shopping for groceries. Others participate in a weekly bingo game with friends or family as a social event or play cards during the lunch break at work. These are examples of unproblematic gambling behaviors common in modern Greenland and for most people gambling in itself is an unproblematic activity which one can choose to engage in and maybe even win some money. However, for a minority the gambling develops into an extensive activity with negative consequences for the person who gambles, and his or her surroundings. This situation is defined as pathological gambling. Pathological gambling – a definition The concept of pathological gambling is rooted in the psychiatric discipline and was first listed as diagnose in 1980 in the third edition of the Diagnostic and Statistical Manual (DSM-III) published by the American Psychiatric Association and in WHO’s ninth edition of the International Classification of Diseases (ICD) in 1977. In the DSM-III pathological gambling was initially defined as an impulse control disorder. This diagnose has been revised twice, first with the revised DSM-III in 1987 (14) and later in the fourth edition of the Diagnostic and Statistical Manual from 1994 (DSM-IV), which was revised in 2000 (DSM IV-R) (15). The revisions from DSM III to IV were of substantial character and the criteria for pathological gambling have been linked to addictive behaviors such as alcohol and drug dependence based on empirical findings, although it is still listed as an impulse disorder (4;16). Currently the definition of pathological gambling is under discussion again in preparations of the fifth edition of the Diagnostic and Statistical Manual (DSM V). In DSM-IV-R, pathological gambling is listed under ‘Impulse-Control Disorders Not Elsewhere Classified’ along with disorders such as Kleptomania and Pyromania: “The essential feature of Pathological Gambling is persistent and recurrent maladaptive gambling behavior (Criterion A) that disrupts personal, family, or vocational pursuits. The diagnosis is not made if the gambling behavior is better accounted for by a Manic Episode (Criterion B).” (15), p.671. The following ten criteria (defined as the DSM-IV-R criteria) for pathological gambling are listed in the DSM IV-R. Fulfillment of five or more of these is diagnosed as pathological gambling in a clinical context. 12 Table1. The DSM-IV-R criteria for pathological gambling Preoccupied Tolerance Loss of control Withdrawal Escape Chasing Lying Illegal acts Risked significant relationship Bailout The individual may be preoccupied with gambling (e.g., relieving past gambling experiences, planning the next gambling venture, or thinking of ways to get money with which to gamble). Most individuals with Pathological Gambling say that they are seeking “action” (an aroused, euphoric state) or excitement even more than money. Increasingly larger bets, or greater risks, may be needed to continue to produce the desired level of excitement. Individuals with Pathological Gambling often continue to gamble despite repeated efforts to control, cut back, or stop the behavior. There may be restlessness or irritability when attempting to cut down or stop gambling. The individual may gamble as a way of escaping from problems or to relieve a dysphoric mood (e.g., feelings of helplessness, guilt, anxiety, depression). A pattern of “chasing” one’s losses may develop, with an urgent need to keep gambling (often with larger bets or the taking of greater risks) to undo a loss or series of losses. The individual may abandon his or her gambling strategy and try to win back losses all at once. Although all gamblers may chase for short periods, it is the long-term chase that is more characteristic of individuals with Pathological Gambling. The individual may lie to family members, therapists, or others to conceal the extent of involvement with gambling. When the individual’s borrowing resources are strained, the person may resort to antisocial behavior (e.g., forgery, fraud, theft, or embezzlement) to obtain money. The individual may have jeopardized or lost a significant relationship, job, or educational or career opportunity because of gambling. The individual may also engage in “bailout” behavior, turning to family or others for help with a desperate financial situation that was caused by gambling. Most of the screening tools used in prevalence surveys and epidemiological research of pathological gambling are based on these DSM-IV-R criteria or the earlier revised DSM-III-R criteria, but operate with different levels of threshold compared to the clinical screening in order to catch the less severe gambling problems along with more serious ones. Pathological gambling is considered a chronic disorder in the DSM-IV-R with a natural evolution from a less to a more severe state over time. Problem gambling – widening the concept of pathological gambling In our study, we use the term problem gambling, which is typically applied in the epidemiological field of gambling research as a wider concept of pathological gambling, when measured at a population level (8). Problem gambling is used to define problematic gambling behavior that may not qualify as pathological gambling if assessed in a clinical context, which is of relevance in order to get 13 an overview of how prevalent more or less severe gambling problems are in a population and thus the need for early prevention and treatment. More specifically problem gambling is used to define a subclinical state of pathological gambling. Internationally the prevalence varies from country to country with a past year prevalence of problem and pathological gambling ranging from less than 2% in the Scandinavian countries (17), and 3.5% in the United States and Canada (4) to 4-5% in several Asian countries (18). The widening of the concept is especially relevant in a public health perspective, where the goal is to target prevention, either towards the general population or towards specific groups, who may be more exposed or vulnerable to the problem. 2.2 Towards a public health perspective on gambling Considering gambling and problem gambling in a public health perspective is a relatively new approach following in the footsteps of the increase in epidemiological surveys estimating national rates for gambling behavior and especially problem and pathological gambling. The public health perspective considers gambling from a societal and population health point of view with a focus on how gambling and problems related to gambling are affecting not just individuals, but families, communities and societies. Furthermore the public health perspective opens up for considerations regarding the influence and significance of structural conditions in a society, which transcends the individuals’ access to a healthy choice regarding gambling. It is important to recognize that a public health approach to gambling is but one perspective among many. In Table 2 different examples of how gambling is viewed are illustrated. Although these are taken from a Canadian context, they reflect the general perspectives in the public debate in Greenland. Statement H represents the public health perspective promoted by Korn and others (1921), who argue in favor of a well-informed evidence-based policy for access to gambling, preventive strategies towards gambling related problems and treatment programs targeted vulnerable population groups. Table 2. Different frames for understanding public policy on gambling proposed by Korn, Gibbens and Azmier (19), p. 237 A. Gambling is a matter of individual freedom; apart from addressing a legitimate concern with crime and the protection of minors, governments should not restrict how people spend their after-tax income. B. Gambling is a recreational activity, a form of entertainment. C. Gambling is a major source of public revenue; one rendered all the more appealing to governments because it can be portrayed as a form of voluntary taxation. D. Gambling is an important tool for economic development through increased tourism and employment, one that may be particularly attractive to Aboriginal communities. E. Gambling addiction is an individual rather than social pathology, and therefore should be treated within a medical model much like other mental disorders. F. Gambling is a cultural artifact that is more deeply embedded in some cultures than it is in others. G. Gambling is a way to escape the class constraints of Canadian society, allowing winners to leap with a single bound into the ranks of the wealthy. H. Gambling is seen within the context of public accountability, public responsibility, and public health. Because gambling is in the public domain in Canada, there is an incumbent responsibility for political leaders to be informed about the costs and benefits of gambling, and to be held publicly accountable for their policy choices. 14 2.3 The role of gambling and problem gambling in a population undergoing social transition Greenland was colonized by Denmark in 1721 and reforms of the Greenlandic infrastructure, industry and welfare during the 20th century were based on Danish administrative systems. In the early 1900 climate warming brought the Atlantic cod to the west coast of Greenland and cod fishing became a major source of cash income. This initiated a movement away from the hunting of seals and whales towards a modern fishing industry. People moved to larger and fewer towns. In 1953 Greenland was given the status of a county in the Kingdom of Denmark. This development brought fundamental reforms with it, and G-50 and G-60 were implemented with the purpose of creating a modern infrastructure to handle the new fishing industry, which was planned to be a main source of revenue for the modern Greenlandic society. During these years extensive infrastructural development occurred, which transformed Greenland from a traditional hunting society into a modern economy, where most people depended on earning wages (22). When the cod disappeared in the 1960s the shrimp arrived in the Disko Bay area in North Greenland. This lead to a substantial growth in this region until the shrimp disappeared from the coastal waters in the 1990. These changes illustrate how population growth and societal changes are closely linked to local conditions such as the availability of fish or shrimp and how rapid these conditions can change. Many communities are still very vulnerable to these changes because the availability of jobs and income from fishing rely on the availability of certain species (23). In 1979 Greenland was granted Home Rule Government and in 2009 Self-rule. Today there are still close ties between Denmark and Greenland. In less than 100 years Greenland has developed from a traditional subsistence based economy to a modern society. The rapid transition places immense social and cultural demands on both individuals and communities (23-25). Despite its large geographical size, the total population of Greenland is only about 57,000 of whom 90% are ethnic Greenlanders (Inuit). Genetically, Greenlanders are Inuit (Eskimos) with a mixture of European, mainly Scandinavian genes. They are genetically and culturally closely related to the Inuit/Iñupiat in Canada and Alaska and, somewhat more distantly, to the Yupiit of Alaska and Siberia (22). Greenland has a total of 80 communities all located along the coast divided into towns and villages. A town is defined historically as the largest community in each of 17 districts. In 2010, the population of the towns varied between 469 to 5,460 and 15,469 in the capital Nuuk while that of villages varied from less than 10 to around 550. In the towns are located district school(s), health centre or hospital, church, district administration and main shops. These institutions are absent or present to a much smaller extent in villages. Village schools are usually limited to 7th grade, after which children have to move to the nearest town in order to complete their schooling. High schools are located in two towns in South and North Greenland respectively and in the capital. The University of Greenland is also located in the capital of Nuuk. 15 Figure 1. Social transition in Greenland. Changes in the percentage of the total population th living in villages in Greenland during the 20 century. The number of persons living in villages in Greenland has been stable around 10,000 since the beginning of the 20th century, but the relative distribution between villages and towns has changed dramatically. During the first half of the 20th century around 80% were living in villages, but this changed around the year 1950 towards the present situation. Today the majority of the population in Greenland lives in towns, more than 25% live in the capital of Nuuk, and only 16% live in villages (22;26). There are also significant differences between the socioeconomic status of inhabitants in towns and villages. In villages the people are in average younger, have a lower income and unemployment rates are higher compared to the towns. In 2007 the average annual income in towns was 179,000 DKK compared to only 98,000 DKK in villages (27). The isolated populations in villages and smaller towns face large challenges with limited opportunities. In contrast, life in the capital reflects contemporary Scandinavian lifestyle with a wide range of educational, occupational and recreational possibilities. Typically a more traditional lifestyle is found in the villages compared to the towns and especially the capital. These differences reflect different stages of social transition in Greenland today, where the traditional Inuit lifestyle of hunting and fishing in villages and smaller towns coexist with the lifestyle of high-educated professionals in larger towns and the capital. There are also great differences between the different regions in Greenland. The majority of the population is concentrated on the south central west coast. Only about 3,500 persons live on the East Coast and only around 1,000 in the far North (Thule). There are also historic differences according to time of colonization. East Greenland was not colonized until the late 19th century and North Greenland not until the late 20th century and thus 200-300 years later than the initial 16 colonization of southern and central Greenland by Hans Egede in 1721 (22). The historic and geographic separation is still reflected in modern Greenland with significant differences between North and East Greenland compared to Midwest and South Greenland. The living conditions in the isolated North and East are harsh and access to education and occupation is very limited compared to the rest of Greenland. Figure 2. Map of Greenland 17 As touched briefly upon in the introduction of the thesis, an increase in social pathologies is a key feature shared by indigenous populations undergoing rapid changes. The high rates of alcohol consumption in the 70s and 80s (28) as well as the high prevalence of mental health problems (29) and suicides have been linked to the ongoing transition (30;31). Different explanations focus on the stress of rapid social change, acculturation and the inadequacy of traditional conflict resolution behaviors in the new, more urbanized environments (24;30;31). Social transition and its potential influence on health is an important framework for the study of gambling behavior and problem gambling among Greenland Inuit in the present thesis. 18 3. MATERIAL AND METHODS 3.1 Inuit health in transition across the Arctic The present thesis is based on data from the Inuit Health in Transition Greenland Survey which is a part of an international cross-arctic collaboration: The Inuit Health in Transition Study (IHIT). IHIT was established with the aim of creating a longitudinal cohort study among the Inuit in Greenland, Canada (Nunavik and Nunavut) and Alaska. The studies in Greenland and Canada (Nunavik in particular) follow similar protocols and a lot of work was put into ensuring comparability between the surveys across regions. The purpose of the collaboration was to start a longitudinal study of the interaction between the environment and genetic factors on the health and disease pattern of the Inuit in Greenland, Canada and Alaska. Thus the data collection in Greenland is part of an international study with data collection in several villages and cities in all three countries. The project is expected to contribute to a better understanding of the health effects of the transition from a traditional lifestyle to a modern, industrialized life, which takes place in most present day developing countries. The present thesis’ focus on problem gambling is one example this. Others are studies of dietary patterns (32;33), obesity (34), diabetes (35), cardiovascular risk factors (36) and physical activity (37). The first round of data collections were carried out between 2004 and 2010 across the different regions. A follow-up has been scheduled in 2014 for both Nunavik and Greenland. In Greenland the follow-up will also include data from registers. Figure 3. Map of Greenland with study communities for the Inuit Health in Transition – Greenland Survey 2005-2010 The Inuit Health in Transition Greenland survey was carried out in 9 towns and 13 villages from 20052010 in Greenland (38). Questions about gambling were included in the self-administered 19 questionnaire from 2006 and onwards and was therefore only carried out in 8 of the 9 towns but in all villages. In 2 of the 8 towns, the questions about gambling were included in a second visit carried out to obtain the desired participation rate. The list of towns included: Nuuk, Qaqortoq, Aasiaat, Maniitsoq, Narsaq, Upernavik, Tasiilaq and Qaanaaq. The Inuit Health in Transition Greenland survey also included Qasigiannguit. The list of villages included: Eqalugaarsuit, Narsarmiit, Aappilattoq, Atammik, Napasoq, Kullorsuaq, Innaarsuit, Aappilattoq, Kuummiut, Tiniteqilaaq, Siorapaluk, Qeqertat, Moriussaq (Figure 3). During the five-year period, the study was carried out during summer in some communities and during winter in others. The logistics of the study did not permit data collection throughout the year in each location or the collection of all data in one season. Data was collected by a team of local persons responsible for the recruitment of participants, a supervisor, one of two laboratory technicians, 2-4 interviewers, and two clinical assistants. The interviews were conducted in both Greenlandic and Danish according to the choice of the participant. A total of 81 persons assisted with data collection and the processing of data. Data collection in the Arctic is characterized by very unique circumstances because most destinations can be difficult to access depending on the weather and season of the year. There are no roads between towns or villages in Greenland, thus towns except Upernavik, Tasiilaq and Qaanaaq were visited by public transport (flight). These towns and all the villages were visited on three expeditions by a chartered boat (M/S Kisaq, figure 4). Kisaq can sail in almost all weather conditions and has accommodation for 12 passengers and large volumes of equipment. It is an unambiguously more convenient alternative to public transport, chartered helicopter or local boat charter. Figure 4. M/S Kisaq 20 3.2 Sample and participation Participants were selected as a stratified random sample of adults aged 18 years and older, born in Greenland or Denmark. Population lists from the central population register were used to initially specify the sample. Faroese people or persons born in other countries were not included. Greenland was divided into 12 strata based on geography (South west coast; Central west coast; North west coast; East Greenland; North Greenland) and community size (towns with ≥ 2000 inhabitants; towns with < 2000 inhabitants; villages). From each of these strata one or more towns and 2-3 villages were selected for the study as being representative of the stratum with regard to living conditions. A random sample was drawn from the central population register to obtain around 300 participants from each town; this number represents the practical limit for a research team during a 4-6 weeks’ visit. Villages were chosen at random in the strata and in the selected villages all adults were invited to participate. Individuals in the sample were contacted in writing with an invitation to participate. Information about the study and examination procedures was given, and the recipients were asked to inform the investigators by letter or phone whether or not they wanted to participate. The samples were revised locally with information about who were not actually living in the community at the time of the examination. Neighbors and the municipality office (in the villages) were good sources of information. Ethnicity as ‘Greenland Inuit’ or ‘Dane’ was determined at enrolment based on the primary language of the participant and self-identification. Only one ethnicity was allowed for each participant. The following concerns Greenlanders only. Participation ranged from 83.3% in the village of Aappilattoq to 55.2% in the village of Napasoq. According to community size, the participation was 61.4% in Nuuk, 65.1% in other large towns, 69.9% in small towns and 68.5% in the villages (p<0.001). Participation rates also varied by age and sex. Women more often participated than men and particularly young men were under-represented. The reasons for non-participation are seen from flow chart 1. There were certain differences between the communities; in particular in the capital, Nuuk, many persons indicated lack of time as the reason for not wanting to participate (17% of the non-participants compared with 2% in the rest of the communities). 21 The Inuit Health in Transition – Greenland Survey 2005-2010 N=6,015 Stratified random sample of adult inhabitants in Greenland (18+) born in Greenland (‘Greenland Inuit’) or Denmark (‘Danes’). Drawn from the central population register N=5010 Revised sample N=1005 Reduction of initial sample: Moved (744) Excluded for logistic reasons (94) Pregnant (60) Deceased (54) Unknown in the community (40) Other reasons (13) N=350 Exclusion of Danes N=1552 Non-participation: Did not want to participate (796) Illness or disability (107) Hunting, fishing or mining (68) Out of town for other reasons (53) Other reasons (23) No contact (505) N=4660 Revised sample ‘Greenland Inuit’ N=3108 Participants in clinical examinations and interview Figure 5. Flow chart 1 We know that persons with serious illness or disability are over represented among the nonparticipants as well as those who tend to move often, and we suspect that socially exposed persons, alcohol abusers and persons who frequently go in and out of jobs and the unemployed likewise are over represented among the non-participants. It was the impression of the interviewers that there was a distinct downwards social trend from the beginning to the end of data collection in a town. In some towns it could be demonstrated that during the first week of the study 10% of those who had made an appointment did not show up, while during the last week of the study as many as 26% did not show up (p<0.001). A social bias in the participation was confirmed by information about income obtained from Statistics Greenland. The Inuit participants in the study had an average personal income in 2005-2010 of DKK 161,000 while those who were refused to participate had an income of DKK 152,000, those who were excluded from the sample DKK 141,000 and those who couldn’t be contacted DKK 134,000 (p<0.001; adjusted for age and sex). For disposable household income per person only those who could not be contacted differed from the rest. Revised sample for the Gambling Study The revised sample for 2006-2010 included 3,892 Greenland Inuit. A total of 2,454 persons participated in the general survey (63%) and 2,189 persons filled out the self-administered questionnaire (56%). Only those who filled out the self-administered questionnaire were included in the present study of gambling behavior and problem gambling. In total 2,012 of these 2,189 22 participants (92%) answered at least one question about gambling. The analyses were based on the 2189 participants, who had the possibility to answer questions about gambling. The study of gambling behavior and problem gambling among Greenland Inuit 2006-2010 Inclusion of gambling questions from 2006 N=4660 Revised sample ‘Greenland Inuit’ 2005-2010 N=768 Reduction of revised sample: Exclusion of revised sample for Qasigiannguit visited in 2005 (413) st Exclusion of participants from 1 visit to Aasiaat in 2005 (135) st Exclusion of participants from 1 visit to Qaqortoq in 2005 (220) N=3892 Revised sample ‘Greenland Inuit’ 2006-2010 N=2454 Participants in clinical examinations and interview N=1438 Non-participation Did not want to participate (758) Illness or disability (91) Hunting, fishing or mining (68) Out of town for other reasons (45) Other reasons (26) No contact (448) N=265 Non-participation in selfadministered questionnaire N=2189 Participants who filled out the self-administered questionnaire N=205 Missing data on gambling behavior N=1984 Gambling behavior N=1542 Problem gambling Answered at least one question regarding gambling behavior past year (the lottery, bingo, slot machines, cards/dice) Answered one or both questions in the lie/bet screen Figure 6. Flow chart 2 23 N=647 Missing data on the lie/bet screen 3.3 Data Collection The participants were informed about the arrival of the team and about the investigation by a personal letter and they were after the arrival of the team contacted by the person responsible for recruitment. On the day of the investigation the participants were asked to show up at an appointed time, fasting (i.e. at least 8 hours without eating or drinking). They were further informed about the investigation and signed an informed consent. From the time of arrival 2.5-3 hours went by. The participants were interviewed (40 min.), filled in a self-administered questionnaire, had various clinical tests performed and were issued with an Actiheart device to monitor physical activity for a 14 days' monitoring of heart rate and movements. At the end of the session, participants were informed about the results of the investigation and were invited to ask questions. When the Actiheart device was returned, a compensation of DKK 200 was paid to each participant. 3.4 Outcomes and exposures Past year gambling behavior The questions about past year gambling behavior measured in the self-administered questionnaire regarded four types of gambling; i.e. the lotteries, bingo, cards/dice and slot machines (Figure 7). Respondents answered how often they had gambled within last year, how much time, they spent each time they gambled and how much money they spent on gambling during last month on each of the four types of gambling. The questions regarding past year gambling behavior are identical with questions included in the Inuit Health in Transition Nunavik Survey, with the exception of the question concerning slot machines, which was not included in Nunavik. Only information on past year gambling and gambling frequency has been used in this thesis. Information on time and money spent on each type of gambling has not yet been analyzed, but will be included in future comparative studies with data from Nunavik. 24 Figure 7. Questions regarding past year gambling behavior in the self-administered questionnaire Past year and lifetime problem gambling Our perception of problem gambling is based on the assumption that extensive gambling can have a damaging influence on your social life and employment as well as your health and economic status, as it is defined in DSM-IV. Following this perspective, it is important to stress the public health perspective underlying this study, which implies an understanding of problems as structural rather than individual. Problem gambling was measured through four questions in the self-administered questionnaire. Two of these questions were combined in a short screen (the lie/bet questionnaire) used in all three papers, while the remaining two questions were used as separate one-item measures of problem gambling included in Paper III. The short screen and the additional one-item measures are described below. 25 Figure 8. Questions regarding problem gambling in the self-administered questionnaire The lie/bet questionnaire The lie/bet questionnaire was originally suggested by Johnson and Hammer (39) and later validated in both treatment (40) and community samples (41). The lie/bet questionnaire represents a twoquestion short version of the 10 DSM-IV criteria (15) for screening pathological gambling. Respondents were asked whether they had lied to friends and family about their gambling activities, and whether they had felt a need to increase bets. Questions are shown in Figure 8 (question 23-24). Both questions were posed regarding past year and previously in life. When these two are combined, it represents a measure for lifetime problem gambling, i.e. problem gambling that has occurred at some point in life whether it is a current and/or previous condition. Persons who answered one of the two questions, but not the other, were kept in the new variable for problem gambling, because one positive answer on either of the two questions qualify you to be considered as a problem gambler. This reduced the number of missing in the final variable. A rather large proportion of individuals indicated they had gambled during past year, when asked about specific types of games, but answered they never gambled in the following questions concerning gambling problems. These were not accepted as non-gamblers, which reduced the total of non-gamblers. International gambling studies have typically reported both past year and lifetime prevalence. The lie/bet screen has been found valid to identify lifetime problem gamblers in a community sample, defined as those who responded positively to five or more of the 10 DSM-IV criteria combined with those who only responded positively to three or four of these criteria (41). The short screen does not qualify to distinguish between pathological and problem gambling. It is important to stress, that the 26 purpose of screening for problem gambling in a large health survey is to investigate an overall prevalence of how widely gambling is affecting a population, which is by no means comparable to a thorough clinical assessment of pathological gambling based on the DSM-IV-R criteria. Self-rated problem gambling Self-rated problem gambling was included as an additional one-item measure. Respondents were asked whether they themselves felt they had a gambling problem or had been told so by others (see question 25 in Figure 8. The purpose of including a self-rated measure for problem gambling was to see how well participants’ own perception corresponded with the lie/bet screen. The question was taken from the revised South Oaks Gambling Screen (SOGS-R) originally developed by Leisure and Blume (42;43). The SOGS-R has been the main instrument used to study the prevalence of problem and pathological gambling, although recently abandoned for newly developed screens for epidemiological research (44;45) such as the 9-item Problem Gambling Severity Index (PGSI) (46), the 17-item National Opinion Research Center DSM-IV Screen for Gambling Problems (NODS) (47) also in a 3-item version called NODS CLiP (48), and the 3-item Brief Biosocial Gambling Screen (BBGS) (49). Too much time and money spent on gambling The second one-item measure of problem gambling regarded whether participants felt they had ever spent too much time or money on gambling during past year or previously (question 22, Figure 8). This item was also included in the Inuit Health in Transition Nunavik Survey, but has not yet been analyzed. We have not been able to combine the data from the two surveys yet either, but this will be done in a future study. Sociodemographic variables Residence at age 10 was obtained from the interview and recoded into village or town. Family job type was determined from questions about job title of participant and spouse and recoded into hunters/fishermen and others. Formal education was determined from questions about highest school education attained and further vocational or academic education and recoded into primary school/high school only, short vocational education (less than three years), and longer vocational/academic education. Age was divided into four groups; 18-24, 25-34, 35-59 and 60+ years. Place of residence was divided into the capital of Nuuk, villages and towns (also used as a measure of social transition). Social transition Two measures of social transition were included. Place of residence The first measure was place of residence, which was divided into villages, towns and the capital because there are substantial differences in lifestyle and living conditions between these places in general. Level of involvement in the ongoing social transition In order to supplement this measure we combined current place of residence and childhood residence with formal education and family job type in a second measure that has previously been used to document changes in cardiovascular risk factors and physical activity among Greenland Inuit (36;37). Six categories of social transition were defined as (A) hunters and fishermen in villages; (B) other inhabitants of villages; (C) blue collar migrants (inhabitants of towns, with no vocational 27 education, having lived in villages at age 10); (D) other blue collar participants (inhabitants of towns, with no vocational education, having lived in towns at age 10); (E) intermediate (inhabitants of towns, with short vocational education); and (F) professionals (inhabitants of towns, with longer vocational or academic education). In order not to misclassify participants who had not yet finished their education and to minimize the proportion of participants outside the work force this measure only included those aged 25–64 years. Traumatic events during childhood Alcohol related problems in childhood home and sexual abuse during childhood were included as traumatic childhood events. Participants were asked through the self-administered questionnaire if there were alcohol problems in their childhood home and whether anyone had forced any kind of sexual activity upon them as a child (before the age of 13). Addictive behaviors Harmful alcohol use (CAGE-C) Harmful alcohol use was measured by the modified CAGE-test: CAGE-C. It is a simple screening tool suited for identifying alcohol problems in populations with a high prevalence of at-risk drinkers. The original CAGE test was based on a four-item questionnaire and measured harmful alcohol use in a lifetime perspective (50). However the validity of the original questionnaire outside a clinical context has been questioned (51) and the sensitivity of the test has been criticized in several studies (52;53). The six-item questionnaire CAGE-C (Table 3) was suggested by Zierau et al. in 2005 (54) and validated against a diagnostic interview based on ICD-10 (55) and DSM-III R (14) criteria. The questionnaire has been used to assess harmful alcohol intake among Greenland Inuit in an earlier study (56). The modified CAGE-test measures harmful alcohol use in a past year perspective and includes a question regarding the number of days per week of alcohol use and a question concerning alcohol intake on weekdays outside meals. CAGE positives were defined by a positive answer in two or more of question 1-4 and 6 or one positive answer in question 1-4 and 6 in addition to alcohol intake on four or more days per week. Table 3. The CAGE-C questionnaire 1 Have you, within the past year, felt that you should cut down on your drinking? Yes/No 2 Have people, within the past year, annoyed you by criticizing your drinking? Yes/No 3 Have you, within the past year, felt bad or guilty about your drinking? Yes/No 4 Have you, within the past year, from time to time had a drink first thing in the morning to steady your nerves or to get rid of a hangover (eye opener?) Yes/No Have many days per week, do you drink alcohol? 5 0-1 day 6 2 days 3 days 4 days 5 days 6 days 7 days Do you drink alcohol on weekdays outside mealtimes? Yes/No Frequent use of marijuana Frequent use of marijuana during past year was measured through two questions in the selfadministered questionnaire. Participants were asked if they had ever smoked marijuana. Those who answered ‘yes, once or a few times’ or ‘yes, several times’ were asked how often they had smoked marijuana during past year. Those who had tried to smoke marijuana and additionally answered they 28 had smoked at least 1-3 times a month during past year were categorized as past year frequent users of marijuana. Those who had never tried to smoke and those who had smoked less than once a month during past year, were categorized together as non-frequent users/non users. Health status Five different measures of health status were included in Paper III. These were self-rated health, two different mental symptoms, long-standing illness and obesity. Self-rated health Self-rated health was measured in the interviewer-based questionnaire by asking respondents to rate their own health within five categories: Excellent, good, fair, poor, very poor. In the analyses selfrated health was dichotomized into an excellent/good vs. fair/poor/very poor self-rated health. Mental symptoms Mental symptoms were measured in the interview questionnaire, by asking respondents whether they had been bothered a little, a lot or not at all by (a) anxiety, nervousness, agitation, or fear (hereafter anxiety); or (b) feeling depressed or unhappy (hereafter depression), in the two weeks preceding the interview. Dichotomous variables were created to identify people reporting feeling anxious vs. those who did not, and people reporting feeling depressed vs. those who did not. Long-standing illness Long-standing illness was assessed through interview by asking: Do you suffer from any long-standing illness, after-effect of an injury, handicap or other long-standing disorder? Yes/no. If a person answered yes, they were asked to specify their illness. Only the dichotomized variable based on yes/no was used in this study. Obesity Height and weight were measured with the participants stripped to their underwear and socks (9). Weight was measured on a standard electronic clinical scale. Body Mass Index (BMI) was calculated based on these measurements (kg/m2) and dichotomized according to a BMI above or below 30. Participants with a BMI above 30 were classified as obese (16). Health behavior Six different measures of health behavior were included in Paper III. These were daily smoking, average daily sedentary time, an unhealthy diet, use of health services during past three months, harmful alcohol use and frequent use of marijuana. Daily smoking Information about daily smoking was obtained from the interview questionnaire. Sedentary time Sedentary time was measured through the interview questionnaire based on two questions regarding time spent on sitting during weekdays and weekend respectively based on the past seven days from the International Physical Activity Questionnaire (IPAQ) (long version) adapted for living conditions in Greenland (17;18). The variable was dichotomized using the median in order to compare the 50% with the most sedentary time to the 50% with the least sedentary time (>3 hours vs. <3 hours daily). 29 Unhealthy diet Information on diet was obtained by an interviewer-administered Food Frequency Questionnaire (FFQ) with portion sizes. The FFQ was developed from information obtained through a 24-hour dietary recall. Questions were asked about 67 food items, including 23 local and 44 imported items (9). An unhealthy diet was defined as 25 E% or more from soda pop, fast food, snacks, sweets and sugar added to coffee or tea (19). Use of health services during past three months Information regarding use of health services was obtained from the interview questionnaire. Consultations with a doctor, nurse or healthcare assistant at the local health center or hospital during the three months preceding the interview was registered as having made use of health services during the past three months. 3.5 Data analysis and statistical methods All analyses were performed using IBM Statistics 19.0. Descriptive statistics of prevalence estimates according to different sociodemographic variables were performed in all three papers. Chi-squared test was used to determine if observed differences between groups were significant (57). The significance level was set at 0.05. To obtain national prevalence estimates, data were weighted for sampling strata by the weight procedure of SPSS. This was done to compensate for the oversampling which took place in certain strata and the variation in participation rate according to age and gender. Most prevalence estimates in Papers I-III were stratified for gender and when relevant also age group and place of residence. Prevalence estimates were also weighted for regional and age differences in the sample. Logistic regression was performed in all three papers and the results were reported as odds ratios (OR) with a 95% confidence interval (57). All outcome variables were constructed as binary variables and all exposures and additional variables that were included in the analyses were treated as categorical variables. An overall analytical model of the associations investigated across papers can be found in appendix 3. Kappa statistics (58) were used to test the agreement between the different measures of problem gambling in Paper III. All logistic regressions were either stratified or adjusted according to gender and age group, because significant differences in gambling behavior and problem gambling between men and women and different age groups have been documented in several prevalence studies. Place of residence, formal education and alcohol problems in childhood were also adjusted for when relevant. These choices are discussed under methodological considerations. 3.6 Validity and completeness of data source Data was double entered by different persons and validated in EpiData (http://www.epidata.dk/). The data files were subsequently imported into the SAS package and combined with results of blood analyses and clinical procedures. The validity of data was checked against permitted values and logical errors. Analyses were performed with SAS v. 9.1 or higher and with SPSS v. 15.0 or higher. 30 3.7 Ethical considerations The study was ethically approved by the Commission for Scientific Research in Greenland. Participants gave their written consent after being informed about the study orally and in writing. Data are treated with confidentiality and participants are guaranteed complete anonymity. This can be a challenge when dealing with small communities, where identities can be obvious even though names are kept confidential. Therefore the anonymity of individuals is considered carefully before results are published. 31 32 4. RESULTS 4.1 Overview of results PAPER I TITLE Gambling behavior and problem gambling reflecting social transition and traumatic childhood events among Greenland Inuit - a cross-sectional study in a large indigenous population undergoing rapid change II Harmful alcohol use and frequent use of marijuana among lifetime problem gamblers and the prevalence of cross-addictive behaviors among Greenland Inuit – evidence from the cross-sectional Inuit Health in Transition Greenland Survey 20062010. III Health status and health behavior associated with frequent gambling and problem gambling in a large indigenous population – A crosssectional study based on The Inuit Health in Transition Greenland Survey 2006-2010. MAIN FINDINGS The study found a comparably high prevalence of lifetime problem gambling among Greenland Inuit which adds problem gambling to the list of social pathologies in Greenland. A significant association between lifetime problem gambling, social transition and traumatic childhood events suggests people caught between tradition and modern ways of life are more vulnerable to gambling problems. The study showed that among more than half of the lifetime problem gamblers, the gambling problems were combined with either a harmful alcohol use (past year), a frequent use of marijuana (past year) or both. The study also found that one or more of these addictive behaviors were present among half of the men, one third of the women and in almost half of the households with children. This indicates that many families in Greenland are presently affected negatively by alcohol, gambling and marijuana. These findings suggest that pathological gambling should be included systematically in future public health strategies in addition to the present focus on alcohol and marijuana. The study found that frequent gambling and lifetime problem gambling were associated with a poorer health status and unhealthy behavior in general. Variation according to different gambling activities and different measures of problem gambling suggests that the associations between gambling and health is a complex process closely related to living conditions and socioeconomic differences among Greenland Inuit, and thus an important issue for public health, in order to reduce social inequalities in health. 4.2 Paper I PAPER I showed the majority of Greenland Inuit (80%) had engaged in at least one of four types of gambling during past year and gender and age differences applied. The lottery was played by four out of five followed by bingo, cards/dice and slot machines. Bingo was more common in villages and towns compared to the capital. People in villages gambled more frequently on cards/dice compared to the capital and in towns while the lottery and slot machines were much more common in the capital and in towns. This indicated a mix of patterns between modern games popular in contemporary Scandinavia and games found to be traditionally popular among Inuit in Nunavik and First Nations and thus reflects the ongoing social transition in Greenland. Regarding problem gambling Paper I showed the past year prevalence of problem gambling to be 4% among men and 3% percent among women. The lifetime prevalence of problem gambling was 16% among men and 10% among women (p<0.0001). The analyses showed lifetime problem gambling 33 was associated with social transition. This was reflected in the higher prevalence of lifetime problem gambling in towns (19%) compared to Nuuk (11%) and villages (12%) (men only, p=0.020) and a lower odds ratios for lifetime problem gambling among both hunters and fishermen in villages as well as among professionals in towns compared to other villagers, blue collar workers in towns and persons with a short vocational education in towns (p=0.023). Growing up with alcohol problems in your childhood home (p=0.001/p=0.002) and having been exposed to sexual abuse in childhood (women only, p=0.030) further increased the odds ratio of lifetime problem gambling. Figure 9 shows how different birth cohorts experience different prevalence rates of lifetime problem gambling, which follows the same pattern as alcohol problems in childhood home and sexual abuse before the age of 13. 40 35 30 25 20 15 10 5 0 -1954 1955-1959 1960-1964 1965-1969 Often experienced alcohol problems in childhood home 1970-1974 1975-1979 Lifetime problem gambling 1980-1985 1985- Sexually abused as a child Figure 9. Prevalence of alcohol problems in childhood home, lifetime problem gambling and sexual abuse in childhood according to birth cohort. Unadjusted percent, weighted for regional differences in the sample. Greenland Inuit 2006-2010. Alcohol problems in childhood home (N=1985, p<0.0001); Lifetime problem gambling (N=1542, p<0.0001); Sexual abuse (N=1359, p<0.0001). 4.3 Paper II Analyses in PAPER II showed that the odds ratio for a harmful alcohol use (men only) and a frequent use of marijuana were significantly higher among lifetime problem gamblers compared to nonproblem gamblers/non-gamblers. One or more addictive behaviors were present among more than half of the men (53%) and among one third of the women (37%) (Figure 10). Among lifetime problem gamblers, the gambling problems were more often than not combined with a harmful alcohol use, a frequent use of marijuana or both – especially among men. The prevalence of lifetime gambling combined with alcohol and/or marijuana in a cross-addictive behavior was 12.2% among men and 3.7% among women. Among lifetime problem gamblers the prevalence of a harmful alcohol use increased with aged, while the prevalence of a harmful alcohol use decreased with aged among the non-problem gamblers. In total the prevalence of one or more addictive behaviors in households with children was 44%. The prevalence of only one addictive behavior in households with children was similar to households without children (32% vs. 28%), but the prevalence of two or more addictive behaviors was slightly 34 higher in households without children compared to those with children (19% vs. 12%) (p<0.0001). The odds ratio for finding one or more addictive behaviors in a household was slightly lower for households with children compared to households without children (OR=0.76; C.I. 95%: 0.60-0.97). Figure 10. Prevalence of lifetime problem gambling, frequent use of marijuana, harmful alcohol use and the different combinations between the three as well as no addictive behavior. Men (left), N=579, missing=404. Women (right), N=605, missing=601. The total prevalence of each of the three addictive behaviors as well as no addictive behavior is written in bold figures. The prevalence of only one addictive behavior or the combination of two or three addictive behaviors is written in ( ). Unadjusted percent weighted for regional and age differences in the sample. Greenland Inuit 2006-2010. 4.4 Paper III PAPER III investigated gambling behavior and problem gambling in a general public health perspective by looking at health behavior and health status among frequent gamblers and lifetime problem gamblers. The analyses showed significant associations between selected measures of health status and health behavior with both gambling behavior and lifetime problem gambling. More frequent gamblers and problem gamblers experienced mental symptoms, smoked daily, enjoyed an unhealthy diet, reported of a poorer self-rated health, a higher prevalence of long-standing illness and had made more use of health services during the past three months compared to those who gambled less than once a month and non-problem gamblers respectively. Exceptions were obesity and sedentary time during the day, where the pattern was reversed; meaning frequent gamblers and lifetime problem gamblers spent less time on sedentary activities during the day and were less obese. Associations varied according to gender, type of gambling and how problem gambling was measured. 35 36 5. DISCUSSION 5.1 Main findings The objective of the thesis was to investigate the prevalence of gambling behavior and problem gambling in a representative sample of Greenland Inuit and its association with social transition, addictive behaviors and health. In short terms, Papers I-III found a high prevalence of especially lifetime problem gambling among Greenland Inuit; a significant association between social transition with both gambling behavior and lifetime problem gambling; a prevalent overlap between lifetime problem gambling and other addictive behaviors (harmful alcohol use and frequent use of marijuana); and a generally poorer health status and unhealthier behavior among lifetime problem gamblers compared to non-problem gamblers and those who never gambled. Main findings in perspective to other studies The prevalence of lifetime problem gambling among Greenland Inuit is high compared to national prevalence estimates from Scandinavia (17;59-61), New Zealand (3;62) and the United States and Canada (4;63), but similar high rates have been found among aboriginal populations in North America (5) and New Zealand (3). The results contribute with new knowledge with regards to understanding the high prevalence rates among indigenous populations in the light of the ongoing social transition. The high prevalence of other addictive behaviors among problem gamblers compared to nonproblem gamblers is in line with international population based studies of co-morbid behavior reviewed by Lorrains et al. (64). However the prevalence of a harmful alcohol use among male lifetime problem gamblers seems relatively high among Greenland Inuit compared to findings in other population based studies. The empirical literature regarding problem gambling and health beyond mental disorders, smoking, substance and alcohol use is limited, but the existing studies found lifetime pathological gambling to be associated with several medical disorders, poor lifestyle choices and worse quality of life (65;66). Our results supplement these findings and contribute with new knowledge regarding the associations between health and frequent gambling. 5.2 Methodological considerations Selection bias Selection bias can occur when the study procedures or the methods of sampling for the study cause a systematic exclusion of individuals who were theoretically eligible for the study (67). As described, participation in the survey required the individual participant to show up at a given destination, at a given time and go through 2.5-3 hours of health examinations, interview and finally fill out a self-administered questionnaire. These procedures are likely to create selection bias because people with few economic and social resources typically will not have the energy to participate. Also they can be harder to reach by mail or telephone. In general, persons with serious illness or disability are over represented among non-participants in populations-based surveys as are 37 those who tend to move often. It is likely that also socially exposed persons, persons with a substance use or an alcohol use disorder as well as the unemployed are over-represented among the non-participants. Analyses of register based income information showed that the personal income of participants was higher than among non-participants. This confirms the social bias known from most studies. For the study of problem gambling this is particularly relevant since especially problem gamblers with the most severe gambling problems could be expected to belong to a group of socially exposed persons, who do not participate in surveys. This can have resulted in an underestimation of the prevalence of both past year and lifetime problem gambling in the study. Stratification and adjustments were used in the statistical models to minimize this bias. The variation in participation rates across the country and between villages, towns and the capital presents a bias for the countrywide estimates. So does the stratification procedure of the random sample, which means that some regions have proportionately more participants despite their small percentage of the total population. This applied to North Greenland (the Thule Area) and Midwest Greenland. Because of logistic challenges it would be almost impossible and very expensive to base the population survey on an unstratified sample. This bias is compensated for through weighting procedures to ensure the extern validity and representativity of the results. In addition to the potential bias caused by sampling method and data collections, the response rate for questions used as key variables in the analyses represent an important source of bias. Analyses showed that response rates to questions about gambling behavior and problem gambling varied according to gender, age group, place of residence and formal education. This was also the case for most of the included measures of health behavior and health status. The odds ratios for having answered the questions regarding the included measures were higher among men than women and among inhabitants in the capital compared with people from towns and villages. Furthermore, the odds ratio decreased with age and increased with level of education. Only response to the question regarding use of health services during the past three months went in a different direction with a decrease in the odds ratio for having answered this question with increasing level of formal education. Consequently, there is an additional social bias in the analyses, which can cause residual confounding. Stratification and adjustment for these variables has been applied to the possible extent, but there are limits as to how much a small sample can be stratified and adjusted due to the risk of type-II errors (discussed below). Another way to deal with the social gradient in the response rates could be to weight data further according to this gradient, but this could potentially be a greater source of misinformation compared to the missing data. Consequently the results must be interpreted with this social bias in response rates in mind. Information bias Information bias occurs if there are errors in the applied measurements, which can lead to the misclassification of individuals. This is a central issue to discuss in relation to the lie/bet screen used to identify problem gamblers in this study, because there is always a risk of including false positives and excluding false negatives from a prevalence estimate. This has to do with the sensitivity, i.e. the probability that the test correctly classifies those with the given condition as positives, and the specificity, i.e. the probability that the test classifies people without the given condition as negatives (67). 38 Three validation studies have been carried out for the lie/bet screen with the DSM-IV criteria as the gold standard. Johnson et al. (39) found a sensitivity of the lie/bet screen of 0.99 and a specificity of 0.91 in their initial validation study of the screen based on men only and a sensitivity of 1.00 and a specificity of 0.85 in a follow-up study which also included women (40). Both of these studies were based on pathological gamblers recruited from Gamblers Anonymous matched with controls. The third validation study carried out by Götestam et al. (41) was based on a population study and found a sensitivity of 0.92 and a specificity of 0.96. Although Johnson et al. found the lie/bet screen to be useful for screening for pathological gambling; this conclusion was based on a study population of pathological gamblers who met the diagnostic criteria of DSM-IV-R. Based on the validation of the lie/bet screen in a population sample, Götestam et al. concluded that the short screen could not be used to discriminate between problem and pathological gambling in a normal population, but was a useful tool for screening for problem gambling including the group of more severe pathological gamblers at the population level. The assessment of problem gambling among Greenland Inuit was based on this strategy, to ensure the validity for screening at the population level. Götestam et al. (41) reported a 0.54% prevalence of lifetime problem gambling based on the lie/bet screen in a community sample of adults (18+) in Norway. This prevalence is a little lower than the prevalence found by Lund and Nordlund (59) in Norway in the same survey year based on the NODS as a screening tool suggesting the lie/bet screen did not overestimate the lifetime prevalence in the Norwegian population despite its brief character. Furthermore the Danish Health Interview Survey from 2005 (68) included the lie/bet screen and found a lifetime prevalence for problem gambling of 2.6% among participants aged 16+ (unpublished results). This prevalence was a little higher than the one found in the Danish Gambling Survey by Bonke and Borregaard (61) mentioned above, where the SOGS-R identified 1.7% lifetime problem gamblers and the NODS identified 0.7% lifetime problem gamblers among adults (18+). Both studies were based on a representative population samples. This suggests that the lie/bet screen slightly overestimated the lifetime prevalence in the Danish population compared to both NODS and SOGS-R. There is a risk that one is categorized as a lifetime problem gambler based on symptoms, which might have occurred one at a time over several years, but not at the same time (4). However, since one symptom is enough to be categorized as a problem gambler based on the lie/bet screen, this is considered to be less of an issue in this study. The sensible character of questions regarding people’s gambling problems represents another potential source of information bias. Although the questions were posed in a self-administered questionnaire to respect the privacy of the respondents, it is a known phenomenon that people tend to underestimate their own bad habits and are influenced by social norms of what is right and wrong, when responding to questions in a survey. Furthermore - according to professionals working with gambling treatment - pathological gamblers are often in denial about their gambling related problems. The same potential risk of information bias applies to the questions about drinking and smoking marijuana included in this study. Another source of information bias is attributed to an imprecise recall of the information retrieved from participants in the study (67). Because questions regarding problem gambling were asked for past year and earlier in life the answers might be subject to recall bias, particularly if potential gambling problems were less severe. People tend to forget the problems they have had in the past and they might seem less severe with time. Participants might also be influenced by a social desirability to respond according to what they think the researcher wants to hear, or according to 39 social and cultural norms. Again this can have led to an underestimation of the prevalence found in this study. Confounding and intermediate factors The risk of confounding from variables that are not included as exposures in a study, but which can lead to a mixing of effects because they influence the relationship between exposure and outcome, are important to consider in any epidemiological study. Rothman and Greenland (67) defines three criteria for a confounding factor: “1. A confounding factor must be an extraneous risk factor for the disease; 2. A confounding factor must be associated with the exposure under study in the source population (the population at risk from which the cases are derived); 3. A confounding factor must not be affected by the exposure or the disease. In particular, it cannot be an intermediate step in the causal path between the exposure and the disease.” (67)p. 132 Given the complexity of addictive behaviors or disorders such as problem gambling, it is difficult to point to specific confounders that are not in some way thought to be part of the explanation and thus rather have a modifying effect as intermediate variables in the relationship between exposure and outcome, cf. the third criteria for a confounding factor. All analyses were stratified or adjusted for gender and age group. These variables were not considered as confounders, but rather as a part of the explanation, i.e. intermediate factors in a causal path between exposure and outcome (67). In addition, most of the analyses were adjusted for place of residence, except when this would result in too few individuals in one or more of the created subgroups. Place of residence was in general not considered as a confounder, but rather as an intermediate factor given the differences in living conditions. This was relevant when investigating different health outcomes in relation to gambling behavior and problem gambling (Paper III), because there are great differences in access to health service, healthy foods, physical activity, etc. between villages, towns and the capital. However, in the analysis of how different types of weekly gambling activities were associated with past year problem gambling, place of residence was considered a confounder because the availability of gambling activities depends on where you live (Paper I). This was the case with regards to slot machines, which are only available in towns and the capital, but not in villages. In Paper II, alcohol problems in childhood home were included in the analyses of the association between lifetime problem gambling and other addictive behaviors, because growing up in a family with problems related to addictive behavior is known to be a contributory cause of addictive behavior later in life. Again, this was not considered a confounder, but an intermediate factor. In Paper III, formal education was included in the stratified analyses in addition to age group and place of residence, based on the well-known association between educational level and people’s health status and health behavior. In general this association means that a higher level of education is associated with a healthier life. Formal education is therefore treated as an intermediate factor and not a confounder. 40 The analysis of the association between the level of involvement in the ongoing social transition and lifetime problem gambling in Paper I is an example of a complex variable that was constructed on the basis of different sociodemographic information as well as childhood conditions. As a consequence it would not make sense to adjust separately for these variables since they were already included indirectly as exposures in the analyses. Type-I and type II-errors An incorrect rejection of the null-hypothesis, stating that there is no difference between the exposed and unexposed, is called a type-I error, and the opposite scenario where the null-hypothesis is false, but not rejected, is called a type-II error (67). Type-II errors are particularly relevant to consider, when working with a relatively small sample size as it is typically the case in research regarding indigenous populations in the Circumpolar North. Stratification and the inclusion of additional variables to ensure proper adjustment often renders very few individuals in each strata. Type-II error then occurs when an association between a given exposure and outcome is missed, because the level of significance for a chi-2 test might not meet the conventional criteria of p<0.05 or because the 95% CI is too large. This occurs because the effect is small and/or observations are too few as well as from different sources of bias (67). As an example there are only two female ‘past year problem gamblers’ from Nuuk and eight male ‘past year problem gamblers’ from villages in the sample. As a consequence, most analyses were carried out for lifetime problem gamblers rather than past year problem gamblers and stratification and adjustment was limited to the variables that were considered the most important. Lessons to learn about measuring problem gambling A general lack of testing and validation of screens used in epidemiological surveys combined with a confusion of concepts creates a weak fundament for comparative research (4;16). The definition of pathological gambling in the majority of the methodological screens used to investigate problem and pathological gambling in epidemiological research has been imported from the DSM-IV-R criteria, but the different levels of gambling problems have been defined for epidemiological use without investigating the validity of the DMS-IV-R criteria in a population context outside the clinical setting. Instead of working in one direction with the aim of developing a gold standard, several new screens have been introduced, many of which have not been validated. As a consequence few prevalence surveys are directly comparable (4;8). Despite this, the prevalence of pathological gambling across countries and methods is remarkably similar. Based on this observation it has been suggested, that the most severe gambling problems are caught despite differences in screening tools (4). However, there is less consistency when it comes to the less severe gambling problems. Given the brief character, the lie/bet screen is likely to cover milder gambling problems along with more severe problems compared to a more comprehensive assessment such as the revised South Oaks Gambling Screen (SOGS-R) (69) or the NORC DSM Screen for Gambling Problems (NODS) (16). This is considered a weakness of the screen. Although the validation studies of the lie/bet screen displayed satisfying levels of sensitivity and specificity, a short screen with a reduced number of questions will inevitably give a result based on less information, and thereby a potentially less valid result. However, short screens are an important tool if gambling is to be investigated in larger population based health surveys because these surveys usually include several topics, which challenges the limit for duration, as to how much time people can be expected to spend on participating in a survey. 41 The NODS CLiP (70) and the Brief Biosocial Gambling Screen (BBGS) (71) are examples of the most recent short screens for problem and pathological gambling targeted population based research, and they have shown excellent sensitivity and specificity in the North American population samples. The NODS CLiP is a three-item short version of the NODS and measures gambling problems in a lifetime perspective. In comparison to the lie/bet screen it also includes the question about lying. The two other questions concern, whether a person has tried to cut down or control gambling activities, and whether a person has been preoccupied with thinking about gambling experiences or planning future gambling activities. A positive answer to one of these three items indicates likely problem or pathological gambling. The three-item BBGS was developed from the National Epidemiological Survey on Alcohol and Related Conditions (72) and measures past year problem or pathological gambling. In comparison to the lie/bet screen, the BBGS also includes a question about having lied to friends or family. The two additional questions concern, symptoms of withdrawal when trying to cut down on gambling, and borrowing money due to financial problems caused by gambling. A positive answer to one of the three questions is considered as possible pathological gambling with a need for clinical evaluation. Having lied to friends and family is included in all three short screens, but other than that, all three screens include different criteria from the DSM-IV-R. This in itself suggests that there is no obvious gold standard in the short screening tools, since different samples have led to the development of different short screens. To enhance the use of the existing short screens and to improve their validity across samples, the short screens should be cross-validated and tested in more than one population, including more vulnerable populations such as ethnic minority groups and indigenous populations. It should also be carefully considered whether or not the DSM-IV criteria should be the gold standard to validate the short screens against or if other aspects besides the ten DSM-IV criteria such as the negative impact on communities and families could be included when screening for gambling problems at the population level. This is especially relevant from a public health point of view. Lesieur (73) has argued, that most epidemiological surveys seriously underestimate the extent of problem and pathological gambling. This is due to the above stated lack of validity for many screens as well as failure to include institutionalized and other specialized populations, and a lack of strategy to handle the level of denial among problem gamblers (74). The critique still seems relevant, and should be included considered in future methodological studies. 5.3 Understanding the nature of problem gambling To provide a better understanding of the development of problem gambling the Pathways Model suggested by Blaszczynski and Nower (75) was discussed in Paper I and III. The Pathways Model argues that problem gamblers are a heterogeneous group with different backgrounds for developing gambling problems and proposes three different pathways: a) One pathway covers problem gamblers with no severe psychological problems prior to their extensive gambling, but where alcohol abuse, depression and anxiety might appear as a result of their gambling; b) a second pathway covers a group of problem gamblers that are characterized by an emotional vulnerability due to for example childhood disturbance. This vulnerability is present before the gambling problems and gambling is used to modify affective states or meet specific needs; c) the third pathway covers a 42 group of highly disturbed individuals with substantial psychological features such as impulsivity and antisocial personality disorder. The high prevalence of a harmful alcohol use and frequent use of marijuana among lifetime problem gamblers found in Paper II should be considered in relation to the first pathway (a), which indicates that substance abuse and alcohol disorders can be a consequence of problem gambling. It would provide an important insight to investigate, if this was the case among the relatively large percentage of persons who reported of lifetime problem gambling in a combination with a harmful alcohol use and/or a frequent use of marijuana. Given the cross-sectional character of our data, it was not possible to investigate, what came first, and how the etiology of pathological gambling could be understood in relation to alcohol and substance use disorders. Few studies contribute with knowledge in this field, and the results are based on retrospective questions asking participants to remember their age of onset for different addictive behaviors (28). The association between traumatic events during childhood and lifetime problem gambling, found in Paper I, suggests that the second (b) and the third (c) pathway to problem gambling through emotional vulnerability and mental health problems is a relevant perspective. These pathways should be considered in further investigations, to gain a better understanding of the high prevalence of lifetime problem gambling among Greenland Inuit. The high prevalence of people, who experienced alcohol problems in their childhood home and were sexually abused during their childhood, can have led to such emotional vulnerability in a large part of the population. This is particularly important to consider for the birth cohorts born in the 1970s, where the prevalence of traumatic childhood events has been found to be highest. Traumatic childhood events was found to be associated with mental health problems among indigenous populations in the North in other studies (29;76;77), and a high prevalence of mental health disorders among Greenland Inuit (29) adds to the argument, of why a pathway to problem gambling through emotional vulnerability and mental health problems should be investigated further. However none of the pathways, discussed by Blaszczynski and Nower (75), were based on empirical findings among indigenous populations, among whom the sociocultural and societal changes have been documented as important determinant of both physical and mental health (24). The associations found in Paper III between gambling and a poorer health as well as unhealthy behavior, suggests that gambling problems could be a result of an even more complex process creating inequalities in health that are related to living conditions and socioeconomic differences among Greenland Inuit. This perspective follows the social epidemiological approach regarding social determinants of health, which states that health follows a social gradient meaning the higher the social position, the better the health (78-84). The focus of epidemiological research should in this perspective be the causes of causes, such as the living conditions and the circumstances that influence peoples’ quality of life and access to a healthy lifestyle. These causes are defined as social determinants of health. Following this line of thought, public health research in Greenland should focus on the social determinants of a poor health and unhealthy behavior among Greenland Inuit and investigate how frequent gambling behavior and gambling problems are linked to social determinants. Although gambling is defined as a chronic and progressive disorder in the DSM-IV used as the gold standard in most epidemiological research on gambling, the few prospective studies that have been 43 conducted, suggest pathological gambling is an intermittent problem rather than a chronic disease and especially people with less severe gambling problems (not meeting clinical DSM-IV-R criteria) have been found to recover from gambling problems on their own rather than moving on to pathological gambling as the inevitable last stage (4;9;73;85). Thus symptoms of disordered gambling can move in two directions: worse or better (4). The high one-year remission rate found among lifetime problem gamblers in Paper I supports these observations. Among 74% of the men and 71% of the women, who reported of gambling problems at some point in their life, did not report of any past year problems. International studies consistently show that the past year prevalence of gambling problems is about two-thirds of the lifetime prevalence, which has been suggested to indicate a recovery rate of one third (8). In a follow-up study in 1998 (62), Abbott et al. re-interviewed the pathological and problem gamblers found in the first national gambling survey in New Zealand in 1991. At follow-up, most of the problem gamblers were no longer problem gamblers, and only a minority had developed a more serious problem and was classified as pathological gamblers. Slutske et al. (86) found problem gambling to be transitory and episodic at the individual level rather than chronic, although the prevalence at the aggregate level remained stable in a four-wave longitudinal study. Finally, a recent review (87) of five prospective studies of gambling behavior found no evidence to support the assumption that individuals cannot recover from disordered gambling. Neither did the review find evidence supporting the assumption that individuals, who have more severe gambling problems, are less likely to improve their condition compared to individuals, who experience less severe gambling problems. Based on these conclusions across studies, the ongoing discussions of how to define pathological gambling in the upcoming fifth version of the Diagnostic and Statistical Manual of Mental Disorders (planned for publication in 2013) seem highly relevant for the understanding of and conceptualization of problem and pathological gambling in future epidemiological studies. The proposed changes imply a new categorization of pathological gambling as a behavioral addiction; changing the name into ‘Disordered Gambling’; eliminating the criterion of ‘illegal acts’ and reducing the threshold for criteria to discriminate between pathological vs. non-pathological from five to four (88;89). Similar discussions were carried out in the 1990s during the preparations of the DSM-IV. A literature review carried out by Lesieur and Rosenthal (90) then found little data on the validity and the classification accuracy of the DSM-III-R criteria, which are almost similar to the current DSM-IV-R criteria. A discussion of the validity and the relevance of the new DSM-V criteria for population-based research should be discussed simultaneously in the field of epidemiological gambling studies. 5.4 Problem gambling in the light of the ongoing social transition The analyses of gambling behavior and problem gambling in relation to the ongoing social transition in Greenland showed lower odds ratios for lifetime problem gambling among both hunters and fishermen in villages as well as among professionals in towns (Paper I). The measure of different levels of social transition was based on information regarding the participant’s current place of residence and childhood residence combined with formal education and family job type. These differences in lifetime problem gambling between hunters and fishermen in villages compared to other villagers; and between professionals in towns compared to the three less educated or unskilled groups in towns, could indicate that there are important social differences between different groups 44 based on childhood conditions combined with place of residence, education and occupation in adult life. Social differences within the population of Greenland Inuit seem relevant for the understanding of the prevalence of problem gambling and health inequalities in general based on the documented importance of social determinants on health (80-83). The challenge is to gain a better understanding of how social transition might influence the constitution of differences between social groups in modern Greenland. The lower rates of problem gambling found among professionals in towns in this study (Paper I) and earlier findings of a better mental health among groups that have integrated successfully into modern Greenlandic society (24;77) could indicate the importance of education combined with living in the capital or a larger town with access to a wider range of opportunities as a successful strategy towards social integration. Social integration is generally considered an important determinant of health in social epidemiological theory (91-95) and the lack of social integration can be attributed to an imbalance in society often seen in relation to fundamental societal changes. The concept of social integration has also been discussed in earlier studies among indigenous peoples in the circumpolar North in relation to acculturative stress, as an explanation of the relationship between cultural changes and mental health (23;24;77;96). The theory of acculturative stress proposed by Berry and Kim (97) defines four different modes of acculturation: integration, separation, assimilation and marginalization resulting from how the importance of maintain one’s own cultural identity and the relationship with other groups is perceived. Integration is considered to be associated with the lowest levels of acculturative stress, but all four modes seem to imply a negative outcome of cultural changes. However the theory has not be empirically verified among Greenland Inuit, and it has been suggested that acculturation as defined by Berry, plays a lesser role for mental health among Greenland Inuit (77;98). The similar low rates of lifetime problem gambling among families of hunters and fishermen in villages could in this perspective be explained by their social integration in a more traditional Inuit lifestyle that is still prevalent in some villages and smaller towns. Hunters and fishermen are naturally integrated in village life where traditional Inuit lifestyle is still prevalent as are professionals in towns where life reflects the modern Greenlandic Society. In contrast village life is more challenging if you are not hunting and fishing because very few educational and occupational opportunities are available. So is the life in a larger town, if you are not skilled or well educated, because expectations and demands for qualifications rise with the level of specialization in modern society. People in towns in Greenland might generally be considered to have the most difficult position in the ongoing social transition because they are caught in the middle of the more traditional life in the villages and the modern life in the capital, but the differences between social groups within villages and towns defined in relation to the ongoing social transition, indicate an even more complex process, which seem to depend on a combination of educational and occupational skills combined with local living conditions and opportunities. The construction of a variable that measures the individual’s level of involvement in the ongoing social transition has tried to incorporate these differences. Although the causality of the association is unclear, it seems as if people caught between modern and traditional lifestyle are more vulnerable to problem gambling because they are neither integrated in the traditional or the modern Greenlandic society, which to some extent coexist. The measure for social transition applied in this study has not been used to investigate differences in 45 health in other Inuit populations. Although mental symptoms were included in one study of cardiovascular risk factors in relation to social transition (36) the measures has not yet been applied systematically in the study of social pathologies among Greenland Inuit other than the present study of problem gambling. However, measuring the level of involvement in the ongoing social transition as a way to capture social differences between groups seems to be a relevant approach for further investigations of health inequalities among Greenland Inuit. This measure has the potential to capture even more aspects of the possible social determinants of health compared to the common indicators of socioeconomic position (99-103). Common indicators such as level of education, occupation and income are without doubt important, and have been demonstrated to influence health among Greenland Inuit (24), but the differences between life in a village compared to a town, or life in East Greenland compared to life in South and Midwest Greenland, childhood conditions and family history are not directly reflected in these indicators. Due to the rapid changes, the social, health and living conditions can also vary fundamentally from generation to generation. This was illustrated by the significant differences in the prevalence of traumatic events during childhood according to birth cohorts (Paper I). The different living conditions, possibilities and demands that characterize the life of different generations and the changes over the lifecourse are important perspectives to include when trying to measure social differences in a population undergoing social transition. This line of thought agrees with recent discussions in social epidemiology with a focus on the lifecourse (99;100;104). It has been argued, that the understanding of socioeconomic patterns in adult health risks to be severely limited, if we ignore how exposures and resources may cascade and accumulate over the lifecourse to effect adult health (101). An understanding of the complexity underlying differences between social groups and birth cohorts among Inuit in Greenland is a prerequisite for future investigations of the social determinants of poor health and unhealthy behavior among Greenland Inuit and how gambling behavior, problem gambling and other social pathologies are linked to these determinants in the light of the ongoing social transition. 46 6. CONCLUSION Gambling is a part of everyday life in Greenland, and the majority of Greenland Inuit engaged in gambling during past year. The patterns of gambling behavior reflected a preference for both modern games that are popular in contemporary Scandinavia (the lotteries), as well as games found to be traditionally popular among Inuit in Nunavik and First Nations (bingo, cards/dice). Men gambled more on the lotteries, slot machines and cards/dice than women, while women gambled more on bingo than men. Problem gambling had occurred at some point in life for 10% women and 16% men, but only about 4% had experienced these problems during past year. Lifetime problem gambling was associated with the level of social transition, illustrated by a lower prevalence of lifetime problem gambling among hunters and fishermen in villages and among professionals in towns, compared to other groups. Having experienced traumatic events during childhood also increased the odds ratio for lifetime problem gambling. Lifetime problem gambling was more often than not combined with a harmful use of alcohol, frequent use of marijuana or both. Among 53% men and 37% women and in almost half of all households with children, one or more addictive behaviors were present. The health status and health behavior among frequent gamblers and lifetime problem gamblers was generally poorer and less healthy, compared to non-problem gamblers and those who never gambled. The association between social transition and lifetime problem gambling may suggest, that people caught between the traditional and modern lifestyles, which co-exist in Greenland, are more vulnerable to gambling problems. Social integration in either a traditional life in the villages or a modern life in the capital or larger towns could contribute to the understanding of differences according to level of social transition, while emotional vulnerability caused by traumatic events during childhood could be a potential pathway for gambling problems among Greenland Inuit. A poorer health and less healthy behavior among frequent gamblers and lifetime problem gamblers further suggests that gambling problems could be linked to more fundamental inequalities in health among Greenland Inuit. However the causality of these associations cannot be established based on the cross-sectional data in this thesis and should be investigated in future prospective studies. 47 48 7. IMPLICATIONS 7.1 For research The findings in this thesis indicate that the level of social transition and traumatic events during childhood could be important aspects of understanding the prevalence and distribution of problem gambling among Greenland Inuit. Prospective studies are needed to investigate the causal relationship of social transition, traumatic childhood events and problem gambling. The study of incidence among vulnerable populations is still a road yet to be taken. Prospective and register-based studies are also needed to investigate the causal relationship in the overlap found in this thesis between problem gambling, harmful alcohol use and frequent use of marijuana. This would lead to a better understanding of what comes first, and how the prevention and treatment of one might prevent other addictive behaviors. The association between frequent gambling, problem gambling and health found in this thesis should be investigated in future register-based and prospective studies in order to identify the social determinants of inequalities in health and how these are linked to the prevalence of problem gambling and frequent gambling. Future qualitative studies should investigate, what motivates people to gamble in Greenland and what contributes to the increase or decrease in gambling frequency? We need to consider, what alternative activities are available on a local basis. A review of the literature regarding gambling among the North American aboriginal populations indicated lack of access to leisure activities in the reservations as an important motivating factor for engaging in gambling activities (5). This could also be the case in smaller communities in Greenland and should be investigated further. If the majority of a smaller community engages in gambling it might be an important part of the social life. Different needs and motivations according to age and gender would be interesting perspectives to include. Short screens for measuring problem at the population level are an important tool in epidemiological research, but the short screens need to be validated in different populations and more research should be put into investigating, how people understand and respond to the questions based on the DSM-IV-R criteria. From a public health point of view, it is important to consider whether the clinical criteria for pathological gambling are the most relevant or whether we need a revised methodological framework that can capture the consequences for families and children affected by gambling problems. There is a need to develop a valid and meaningful paradigm for social position among Inuit in Greenland and more generally among northern indigenous populations for use in epidemiological research of change in health conditions. Such measures should build on a lifecourse perspective and include socioeconomic variables, intergenerational differences and local living conditions, and incorporate people’s position in relation to the ongoing social transition. This work can build on the existing measure for social transition used in this thesis, but should also include qualitative studies and longitudinal data in order to gain a better understanding of how social transition is experienced over time by different social groups across different communities and regions in Greenland. 49 Future research should also contribute to a better understanding of why undergoing rapid social transition has led to an increase in social pathologies across indigenous populations in order to prevent a further increase of problem gambling as well as alcohol use disorder, substance use disorders and mental health problems in the future. This research should look into why some population groups seem caught between traditional and modern way of life, while others integrate well. This would contribute to the understanding of the causes behind the causes and social determinants of both mental and physical health, as well as the importance of social integration (as defined in the social epidemiological literature) for health among Greenland Inuit, with relevance for other indigenous populations in the North. 7.2 For public health Problem gambling should be included systematically in public health programs and more specifically in strategies for treatment and prevention targeted the field of addictive behaviors, which at present has only included focus on alcohol and marijuana among adults. Treatment strategies should incorporate a diverse understanding of problem gambling as well as other addictive behaviors, because more and more evidence points towards the heterogeneity of these groups, and thus different needs should be met in order for prevention and treatment to have an impact. This includes the perspective of different pathways to problem gambling, poor health, and unhealthy behavior as well as other addictive behaviors given the associations with social transition and traumatic events during childhood. The higher prevalence of problem gambling among those, who often experienced alcohol problems in their childhood home and were sexually abused are examples of traumatic events that should be taken into account in treatment strategies. The prevalence of combined addictive behaviors is another example. One or more addictive behaviors were found in almost half of all families with children. Prevention targeted families seems crucial to increase the quality of life among future generations and reduce the prevalence of social pathologies. Improving the lives of families in Greenland is already a high priority in public health strategies, but prevention and treatment of gambling problems have not been included systematically in these strategies yet. The association between alcohol, hash and marijuana suggest that health professionals and social workers should consider including assessment for all three addictive behaviors when working with people in need of treatment. 50 8. SUMMARY During recent years gambling behavior and pathological gambling has become a much-debated subject in Greenland. The economic and social problems for individuals, families and communities, which extensive gambling can lead to are of great concern. In less than 100 years Greenland has developed from a traditional subsistence based economy to a modern society. The rapid transition places immense social and cultural demands on both individuals and communities. An increase in social pathologies such as violence, suicide, alcohol and substance use is a key feature shared by indigenous populations undergoing similar social transition and represent major challenges for public health in Greenland. More knowledge was needed to determine the role of gambling in Greenland. The objective of the thesis was to investigate the prevalence of gambling behavior and problem gambling in a representative sample of Greenland Inuit and its association with social transition, addictive behaviors and health. The overall objective was investigated in three Papers. Data were derived from the Inuit Health in Transition Greenland Survey carried out in 9 towns and 13 villages from 2005-2010 in Greenland. The survey combined clinical examinations with an interviewer based questionnaire and a self-administered questionnaire and obtained an overall participation rate of 64.9%. The main findings across papers were i) a high prevalence of lifetime problem gambling among Greenland Inuit (men 16%; women 10%); ii) a significant association between gambling behavior and problem gambling with social transition and traumatic events during childhood; iii) a significant cooccurrence of problem gambling with other addictive behaviors and iv) significant associations between selected measures of health status and health behavior with both gambling behavior and lifetime problem gambling. Based on the main findings it is argued that problem gambling can be added to the list of social pathologies in Greenland, and it is suggested that people caught between tradition and modern ways of life are more vulnerable to gambling problems. Furthermore it is argued that problem gambling should be included systematically in future public health strategies, treatment programs and interventions in Greenland because there is a prevalent overlap between lifetime problem gambling with a harmful alcohol use and frequent use of marijuana. Finally it is suggested, that the association between frequent gambling, problem gambling and health could indicate that gambling and problem gambling among Greenland Inuit is linked to a complex process closely related to social determinants of health, and thus an important issue for public health intervention, in order to reduce social inequalities in health. Implications for research and public health are discussed in relation to the main findings. 51 9. RESUMÉ Gennem de seneste år har pengespil og ludomani været et tilbagevendende emne i den offentlige debat i Grønland. Der har især været fokus på de økonomiske og sociale problemer som ludomani kan føre med sig. Både for den enkelte, men også for familien og lokalsamfundet. På mindre en 100 år har Grønland udviklet sig fra et traditionelt fangersamfund til et moderne samfund. Den hurtige udvikling stiller store sociale og kulturelle krav til den enkelte og til samfundet. En øget forekomst af de såkaldte sociale patologier så som vold, selvmord, alkohol- og hashmisbrug er et vilkår, der deles af oprindelige befolkninger i social transition. Disse forhold udgør en stor udfordring for folkesundheden i Grønland, og der var behov for mere viden om hvilken rolle pengespil og ludomani spillede i denne sammenhæng. Afhandlingen havde til formål at undersøge forekomsten af pengespil samt ludomani og sammenhængen med social transition, misbrugsadfærd og helbred i et repræsentativt udsnit af grønlændere. Dette formål er blevet undersøgt gennem tre videnskabelige artikler. Afhandlingen er baseret på data fra Befolkningsundersøgelsen i Grønland 2005-2010 (Inuit Health in Transition Greenland Survey). Data er indsamlet i 9 byer og 13 bygder i forskellige dele af Grønland og omfattede kliniske undersøgelser, et interviewerbaseret spørgeskema samt et selvudfyldt spørgeskema. Den overordnede deltagerprocent var 64.9%. Afhandlingen viser, i)at forekomsten af livstids problem spil blandt grønlændere er høj (mænd 16%; kvinder 10%); ii) at der er sammenhæng mellem pengespil og problem spil med social transition; iii) at der er et forholdsvist stort overlap med andre former for misbrugsadfærd blandt problemspillere; iv) samt en generel forekomst af dårligere helbred og usunde vaner blandt dem, der spiller ofte og problemspillere. Baseret på disse resultater argumenteres der i afhandlingen for, at problemspil kan tilføjes til listen over sociale patologier i Grønland, ligesom det kunne tyde på, at folk der er fanget mellem en traditionel og en moderne livsstil er mere sårbare overfor problemer med pengespil. Der argumenteres desuden for, at ludomani og problemspil bør inkluderes systematisk i folkesundhedsstrategier, behandlingsindsatser og interventioner fremover, fordi sammenfaldet mellem problemspil og andre former for misbrugsadfærd er relativt stort. En høj forekomst af misbrug i husstande med børn gør det ligeledes nødvendigt at målrettet disse indsatser mod udsatte familier. Afslutningsvist argumenteres der for, at sammenhængen mellem hyppigt pengespil og problemspil med mere generelle helbredsforhold kan være tegn på, at forekomsten af problemspil er knyttet til en række grundlæggende levevilkår og sociale forhold, der indvirker på sundheden. Dette understreger vigtigheden af at inddrage problemspil i kommende folkesundhedsprogrammer med henblik på at reducere den sociale ulighed i sundhed i Grønland. Resultaternes betydning for folkesundhedsområdet samt behovet for mere viden diskuteres i afhandlingen. 52 10. EQIKKAANEQ Ukiuni kingulliunerusuni aningaasanoorajunneq aningaasanoornermullu nakkaassimaneq Kalaallit Nunaanni oqallisaallattaajualerpoq. Aningaasanoornermut nakkaassimanerup inunnut ataasikaanut, ilaqutariinnut najukkamilu innuttaasunut, aningaasaqarnikkut inuttullu atukkatigut sunniutai, pingaarnertut qitiutinneqarput. Ukiut untritillit inortut ingerlanerini Kalaallit Nunaat piniartuunermiit inooriaatsimut nutaamut ikaarsaarpoq. Inuiaqatigiit taama sukkatigisumik ineriartornerat, kulturikkut inuttullu inuunermut- inunnut ataasiakkaanut inuiaqatigiinnullu- annertuumik piumasaqaatitaqarpoq. Inuiaqatigiit nappaataannik taaneqartartut soorlu nakuuserneq, imminut toqunneq, imigassamik hashimillu atornerluineq annertuumik atugaasut nunallu inooqqavini allani aamma atuuttut, peqqissutsimut annertuumik unammillernartuupput. Ilisimatusaatitut allaaserisap: 1) aningaasanoorajunnerup inuuneq tamaat isigalugu kalaallit akornanni annertuumik atugaanera (angutit 16%-ii; arnat 10 %-ii); 2) aningaasanoorajunnerup atornerluinernik allanik ilaqartinneqartarnera; 3)kiisalu peqqinnginnerup piqqinnanngitsunillu ileqqoqarnerup aningaasanoorajuttuni aningaasanoornermullu nakkaassimasuni nalinginnaasuunera takutippaa. Ilisimatusaatitut allaaserisap inerneri tunngavigalugit, aningaasanoornermut nakkaassimanerup Kalaallit Nunaanni inuiaqatigiit nappaataat pillugit nalunaarsukkanut ilanngunneqarsinnaanera tunngavilersorneqarpoq, taamatuttaaq inuit qangatut inooriaatsip inooriaatsillu nutaap akornanni unittoortut aningaasanoorajunnermik ajornartorsiuteqalernissamut sanngiiffeqarnerusorinarsinnaapput. Aningaasanoornermut nakkaassimanerup atornerluinerillu allat ataqatigiinnerat annertungaatsiarmat, siunissami aningaasanoorajunnerup aningaasanoornermullu nakkaassimanerup innuttaasut peqqissuunissaat pillugu suliniutinut, katsorsaanernut allannguiniarlunilu akuliunnernut ilaatinneqartariaqarnissaat tunngavilersorneqarportaaq. Ilisimatusaatitut allaaserisaq 2005-imiit 2010-mut Kalaallit Nunaanni innuttaasut peqqissusaannik misissuisitsinermi paasissutissanik tunngaveqarpoq (Inuit Health in Transition Greenland Survey). Paasissutissat Kalaallit Nunaanni nunap immikkoortuini assigiinngitsuni- illoqarfinni qulaaluani nunaqarfinnilu 13-ini inersimasut akornanni- katersorneqartut, misissortinnerupput apersuilluni immersuinerullutik namminerlu apeqqutinik akiuilluni immersuinerullutik. Ataatsimut katillugit peqataasut 64,9 %-iupput. 53 54 11. REFERENCES (1) PAARISA - Department of Health GG. Gambling and gambling patterns [In Danish]. Nuuk: PAARISA - Government of Greenland; 2006. 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Place effects on health: how can we conceptualise, operationalise and measure them? Social Science & Medicine 2002;55(1):125-39. (104) Lynch J, Smith GD. A life course approach to chronic disease epidemiology. Annual Review of Public Health 2005;26:1-35. 61 62 APPENDIX 1 ID: Dette spørgeskema indeholder en række personlige spørgsmål om private forhold, som mange mennesker helst vil holde for sig selv. Når du er færdig med at besvare spørgsmålene, lægger du skemaet i en konvolut og lukker den. Konvolutten bliver først åbnet af den forsker, der er ansvarlig for undersøgelsen. Oplysningerne bliver behandlet fortroligt, og der vil ikke blive offentliggjort resultater, som kan føres tilbage til dig. Du svarer på spørgsmålene ved at sætte kryds ud for det svar, du synes passer bedst. Nogle steder kan du evt. sætte flere kryds. Hvis der er spørgsmål, som du ikke bryder dig om at svare på, så spring det over og gå videre til næste spørgsmål. 63 De følgende spørgsmål handler om hvor meget tid og hvor mange penge, du bruger på at spille bingo, Lotto, kort eller terninger og lignende 18. Hvor ofte har du spillet bingo inden for det sidste år? hver dag eller næsten hver dag ................................................ 3-6 gange om ugen .................................................................. 1-2 gange om ugen .................................................................. 1-3 gange om måneden ............................................................ sjældnere .................................................................................. aldrig ........................................................................................ 1 2 3 4 5 6 Hvor lang tid bruger du normalt på det, hver gang du spiller bingo? _____ timer Hvor mange penge bruger du normalt på en måned på at spille bingo? kr. 19. Hvor ofte inden for det seneste år har du spillet Tips, Lotto, Skrabespil, Joker eller lignende spil? hver dag eller næsten hver dag ................................................ 3-6 gange om ugen .................................................................. 1-2 gange om ugen .................................................................. 1-3 gange om måneden ............................................................ sjældnere .................................................................................. aldrig ........................................................................................ 1 2 3 4 5 6 Hvor mange penge bruger du normalt på en måned på disse typer af spil? kr. 64 20. Hvor ofte inden for det seneste år har du spillet på spillemaskiner (enarmede tyveknægte)? hver dag eller næsten hver dag ................................................ 3-6 gange om ugen .................................................................. 1-2 gange om ugen .................................................................. 1-3 gange om måneden ............................................................ sjældnere .................................................................................. aldrig ........................................................................................ 1 2 3 4 5 6 Hvor lang tid bruger du normalt på det, hver gang du spiller på spillemaskiner? _____ timer Hvor mange penge bruger du normalt på en måned på at spille på spillemaskiner? kr. 21. Hvor ofte inden for det seneste år har du spillet kort, terninger eller andre lignende spil om penge? hver dag eller næsten hver dag ................................................ 3-6 gange om ugen .................................................................. 1-2 gange om ugen .................................................................. 1-3 gange om måneden ............................................................ sjældnere .................................................................................. aldrig ........................................................................................ 1 2 3 4 5 6 Hvor lang tid bruger du normalt på det, hver gang du spiller kort, terninger eller lignende? _____ timer Hvor mange penge bruger du normalt på en måned på disse typer af spil? kr. 65 22. Har du nogensinde følt, at du har brugt for mange penge eller for megen tid på spil? ja, inden for det seneste år ....................................................... ja, tidligere ............................................................................... nej ............................................................................................ jeg spiller aldrig ....................................................................... 23. Har du nogensinde løjet (for familiemedlemmer, venner, kollegaer eller lærere) om, hvor meget du spiller, hvor meget du har tabt, eller hvor stor din spillegæld er? ja, inden for det seneste år ....................................................... ja, tidligere ............................................................................... nej ............................................................................................ 24. 1 2 3 Har du nogensinde haft behov for at spille med større og større indsatser (for at opnå den samme følelse af spænding)? ja, inden for det seneste år ....................................................... ja, tidligere ............................................................................... nej ............................................................................................ 25. 1 2 3 4 → gå til spm. 26 1 2 3 Har du nogensinde selv tænkt, at du havde et spilleproblem, eller fået at vide af andre, at du havde et spilleproblem? ja, inden for det seneste år ....................................................... ja, tidligere ............................................................................... nej ............................................................................................ 66 1 2 3 APPENDIX 2 ID: Apersuiffissiaq una inuppassuit namminneerlutik pigerusutaannik inunnut tunngasunik apeqqutinik arlalinnik imaqarpoq. Apeqqutit akineri naammassigukkit immersuiffissaq allakkat puussaannut ikeriarlugu taanna matussavat. Allakkat puuat misissuinermut akisussaalluni ilisimatusartumit aatsaat ammarneqassaaq. Paasissutissat matoqqasumik suliarineqassapput, inernernillu ilinnut sammitinneqarsinnaasunik tamanut tusarliisoqarnavianngilaq. Akissutinut ilinnut tulluutsinnerusavit nalaasigut nalunaaqutsiillutit apeqqutit akissavatit. Apeqqutit ilaanni arlalinnik nalunaaqutsiisarsinnaavutit. Apeqqutit ilaat akerusunngisatit alluinnarlugit apeqqummut tullermut ingerlaqqiinnassaatit. 67 Apeqqutit tulliuttut piffissaq qanoq annertutigisoq aningaasanoornermut, bingo, Lotto, nallukattarnermut assigisaannullu atuisarnermut tunngasuupput 18. Ukiup kingulliup iluani qanoq akulikitsigisumik binkortarpit ? ullut tamaasa ullulluunniit tamangajaasa .................................. sapaatip akunneranut 3-6-riarlunga .......................................... sapaatip akunneranut 1-2-riarlunga .......................................... qaammammut 1-3-riarlunga ..................................................... akuttunerusumik ....................................................................... naamerluinnaq .......................................................................... 1 2 3 4 5 6 Piffissaq qanoq annertutigisoq naliginnaasumik bingonermut atortarpiuk? nalunaaquttap akunneri _____ Aningaasat qanoq amerlatigisut naliginnaasumik bingornermut atortarpigit? kr. 19. Ukiup kingulliup iluani qanoq akulikitsigisumik Lotto, Tips, kiliugassat (skrabespil), Jokeri assigisaanillu pisisarpit? ullut tamaasa ullulluunniit tamangajaasa .................................. sapaatip akunneranut 3-6-riarlunga .......................................... sapaatip akunneranut 1-2-riarlunga .......................................... qaammammut 1-3-riarlunga ..................................................... akuttunerusumik ....................................................................... naamerluinnaq .......................................................................... 1 2 3 4 5 6 Aningaasat qanoq amerlatigisut naliginnaasumik eqquiniutinut taakkununnga atortarpigit? kr. 68 20. Ukiup kingulliup iluani qanoq akulikitsigisumik maskiina aningaasanoorut atortarpiuk? ullut tamaasa ullulluunniit tamangajaasa .................................. sapaatip akunneranut 3-6-riarlunga .......................................... sapaatip akunneranut 1-2-riarlunga .......................................... qaammammut 1-3-riarlunga ..................................................... akuttunerusumik ....................................................................... naamerluinnaq .......................................................................... 1 2 3 4 5 6 Piffissaq qanoq annertutigisoq naliginnaasumik maskiinanut aningaasanoorutinut atortarpiuk? nalunaaquttap akunneri _____ Aningaasat qanoq amerlatigisut naliginnaasumik maskiinanut aningaasanoorutinut atortarpigit? kr. 21. Ukiup kingulliup iluani qanoq akulikitsigisumik nallukattat, pinnguaatillu assigisaat atorlugit aningaasanoortarpit? ullut tamaasa ullulluunniit tamangajaasa .................................. sapaatip akunneranut 3-6-riarlunga .......................................... sapaatip akunneranut 1-2-riarlunga .......................................... qaammammut 1-3-riarlunga ..................................................... akuttunerusumik ....................................................................... naamerluinnaq .......................................................................... 1 2 3 4 5 6 Piffissaq qanoq annertutigisoq naliginnaasumik nallukattarlutit assigisaannullu atortarpiuk? nalunaaquttap akunneri _____ Aningaasat qanoq amerlatigisut naliginnaasumik qaammatip ingerlanerani nallukattarlutit assigisaanullu atortarpigit? kr. 69 22. Qaqugukkulluunniit aningaasat amerlavallaartut imaluunniit piffissaq annertuvallaartoq aningaasanoortarnermut atorsimallugit misigisarsimavit? aap, ukiup kingulliup ingerlanerani .......................................... aap, siornatigut ......................................................................... naamik ..................................................................................... aningaasanoormeq ajorpunga .................................................. 23. Qaqugukkulluunnit sallusimavit (Ilaquttannut, ikinngutinnut, suleqatinnut imaluunniit ilinniartitsisunnut) aningaasanoornermut tunngatillugu qanoq annaasaqarsimallutit, imaluunniit qanoq akiitsut annertutiginerinut? aap, ukiup kingulliup ingerlanerani .......................................... aap, siornatigut ......................................................................... naamik ..................................................................................... 24. 1 2 3 Qaqqugukkulluunnniit immeraanermut akiliut annertusisariaqarsimallugu pisariaqartissimaviuk (pissanganassusia misigerusullugu)? aap, ukiup kingulliup ingerlanerani .......................................... aap, siornatigut.......................................................................... naamik ..................................................................................... 25. 1 2 3 4 → apeqq 26 nuugit 1 2 3 Qaqugukkulluunniit eqqarsaatigisimaviuk aningaasanoortarnermut tunngatillugu ajornartorsiuteqarlutit, imaluunniit allanit aningaasanoortarnermut tunngatillugu ajornartorsiuteqartutit oqarfigineqarsimavit? aap, ukiup kingulliup ingerlanerani .......................................... aap, siornatigut ......................................................................... naamik ..................................................................................... 70 1 2 3 APPENDIX 3 SOCIAL TRANSITION PROBLEM GAMBLING ADDICTIVE BEHAVIORS (Paper II) GAMBLING BEHAVIOR HEALTH BEHAVIOR & HEALTH STATUS (Paper III) TRAUMATIC EVENTS IN CHILDHOOD (Paper I) AGE GROUP / GENDER/PLACE RESIDENCE 71 72 PAPERS I-III 73 74 PAPER I Larsen CVL, Curtis T, Bjerregaard P. Gambling behavior and problem gambling reflecting social transition and traumatic childhood events among Greenland Inuit - a cross-sectional study in a large indigenous population undergoing rapid change; Journal of Gambling Studies, 2013, 29 (4): 733-48. J Gambl Stud DOI 10.1007/s10899-012-9337-6 ORIGINAL PAPER Gambling Behavior and Problem Gambling Reflecting Social Transition and Traumatic Childhood Events Among Greenland Inuit: A Cross-Sectional Study in a Large Indigenous Population Undergoing Rapid Change Christina Viskum Lytken Larsen • Tine Curtis • Peter Bjerregaard Ó Springer Science+Business Media New York 2012 Abstract An increase in social pathologies is a key feature in indigenous populations undergoing transition. The Greenland Inuit are a large indigenous population constituting a majority in their own country, which makes it possible to investigate differences within the population. This led us to study gambling behavior and problem gambling among Greenland Inuit in relation to the ongoing social transition and traumatic events during childhood. A large representative cross-sectional study was conducted among Greenland Inuit (n = 2,189). Data was collected among adults (18?) in 9 towns and 13 villages in Greenland from 2005 to 2010. Problem gambling, gambling behavior and traumatic childhood events were measured through a self-administered questionnaire. The lie/bet screen was used to identify past year and lifetime problem gambling. Social transition was measured as place of residence and a combination of residence, education and occupation. The lifetime prevalence of problem gambling was 16 % among men and 10 % among women (p \ 0.0001); and higher in towns (19 %) compared to the capital of Nuuk (11 %) and in villages (12 %) (men only, p = 0.020). Lifetime problem gambling was associated with social transition (p = 0.023), alcohol problems in childhood home (p = 0.001/ p = 0.002) and sexual abuse in childhood (women only, p = 0.030). A comparably high prevalence of lifetime problem gambling among Greenland Inuit adds problem gambling to the list of social pathologies in Greenland. A significant association between lifetime problem gambling, social transition and traumatic childhood events suggests people caught between tradition and modern ways of life are more vulnerable to gambling problems. C. V. L. Larsen (&) P. Bjerregaard National Institute of Public Health, University of Southern Denmark, Oester Farimagsgade 5A, 2, 1353 Copenhagen, Denmark e-mail: [email protected] P. Bjerregaard e-mail: [email protected] T. Curtis Local Government Denmark, Copenhagen, Denmark e-mail: [email protected] 123 J Gambl Stud Keywords Problem gambling Gambling behavior Inuit Indigenous health Social transition Introduction During recent years gambling behavior and pathological gambling has become a muchdebated subject in Greenland. The economic and social problems for individuals, families and communities, which extensive gambling can lead to are of great concern (Paarisa 2006). This Study represents the first population-based survey regarding gambling behavior and problem gambling conducted among Inuit in Greenland. In only 60 years Greenland has developed from a traditional subsistence based economy into a modern society. The rapid transition places immense social and cultural demands on both individuals and communities (Berner et al. 2005; Bjerregaard and Curtis 2002). An increase in social pathologies such as violence, suicide, alcohol and substance use is a key feature shared by indigenous populations undergoing similar social transition (Bjerregaard et al. 2004). In Greenland, the high proportion of the adult population who experienced alcohol problems in their childhood home and a similar high prevalence of persons who were sexually abused, as children are examples of such pathologies. Especially the generations growing up in the 70s and 80s, when the consumption of alcohol was at its highest (Statistics Greenland 2002), have been exposed to traumatic events during childhood. Despite its large geographical size, the total population of Greenland is only about 57,000 of whom 90 % are ethnic Greenlanders (Inuit). Genetically, Greenlanders are Inuit (Eskimos) with a mixture of European, mainly Scandinavian genes. They are genetically and culturally closely related to the Inuit/Iñupiat in Canada and Alaska and, somewhat more distantly, to the Yupiit of Alaska and Siberia (Young and Bjerregard 2008). Greenland was colonized by Denmark in 1721 and reforms of the Greenlandic infrastructure, industry and welfare during the 50s and 60s were based on Danish administrative systems. In 1979 Greenland established its own Home Rule Government and in 2009 Selfrule was assumed. Today there are still close ties between Denmark and Greenland. Greenland has a total of 80 communities all located along the coast divided into towns and villages. A town is defined historically as the largest community in each of 17 districts. In 2010, the population of the towns varied between 469 to 5,460 and 15,469 in the capital Nuuk while that of villages varied from less than 10 to around 550. In the towns are located district school(s), health centre or hospital, church, district administration and main shops. These institutions are absent or present to a much smaller extent in villages. The isolated populations in villages and smaller towns face the largest challenges with limited opportunities. In contrast, life in the capital reflects contemporary Scandinavian lifestyle with a wide range of educational, occupational and recreational possibilities (Berner et al. 2005). Typically a more traditional lifestyle is found in the villages compared to the towns and especially the capital. These differences reflect different stages of social transition in Greenland today where the traditional Inuit lifestyle of hunting and fishing in villages and smaller towns coexist with the lifestyle of well-educated professionals in larger towns and the capital. Public health professionals have pointed to a negative impact from bingo and card games on families and communities. In particular bingo has been suspected to lead to neglect of children because it is frequently played in the evening, where children especially need their parents’ attention (Paarisa 2006). Bingo is played all over Greenland through the 123 J Gambl Stud radio and in local community halls and sports centers. Local radio stations, societies and sport clubs for which the revenue serves as the primary source of income organize most bingo games. In most towns and villages bingo is available on a daily basis and some places bingo is played several times a day. Gambling on cards/dice presumably takes place in private settings, but no official records document the extent of gambling in this area, because it is illegal. Despite the lack of evidence, it is well known within Greenland that card games are played extensively on the East coast, where the traditional social gatherings ‘Kaffemik’ are often turned into gambling tournaments. It seems bingo and card games are more popular among Inuit in the Arctic compared to their non-indigenous neighbors. The Inuit Health in Transition Study conducted in Nunavik, Canada, found 23 % men and 50 % women aged 15? had played bingo during past year and 24 % had gambled on cards/dice (Muckle et al. 2007). Furthermore, a status report regarding gambling problems in First Nations and Inuit Communities of Québec, found bingo to be one of the most popular games among both Inuit and Cree (Papineau 2010). In comparison only 9 % among the non-Inuit population of Québec played bingo past year and less than 1 % had gambled on cards (Muckle et al. 2007). In Scandinavia the past year prevalence for both bingo and card games was similarly low in recent national surveys (Lund and Nordlund 2003; Bonke and Borregaard 2006; SWELOGS 2011). Several studies have found a higher prevalence of pathological gambling among indigenous populations and ethnic minorities compared to the general population within the same region (Abbott and Volberg 2000; Shaffer et al. 2004; Wardle et al. 2011). Most often these populations are smaller marginalized groups. Inuit constitute the majority of the population in Greenland and the present study therefore provides a unique opportunity to investigate problem gambling in a large indigenous population that is not marginalized. The increased public health awareness regarding gambling problems and a general increase in social pathologies in Greenland during the last 60 years led us to study gambling behavior and problem gambling among Inuit in relation to social transition. We hypothesized gambling behavior and problem gambling is associated with community specific living conditions and the level of involvement in the ongoing social transition. Further we hypothesized the highly prevalent traumatic events during childhood, such as alcohol problems in childhood home and sexual abuse, are associated with problem gambling (Blaszczynski and Nower 2002; Hodgins et al. 2010). The objectives of the study were thus to analyze (a) the prevalence of gambling behavior and problem gambling and (b) its association with social transition and traumatic events during childhood. Materials and Methods Study Design, Setting and Participants Data were derived from the cross-sectional Inuit Health in Transition Greenland Survey 2005–2010—a population based general health study among adults (18?). A full methodological report of the study is published elsewhere (Bjerregaard 2011). Greenland was divided into 12 strata based on geography and community size. From each region a number of towns and villages were selected for the study. A random sample was drawn from the central population register to obtain around 300 participants from towns included. In the selected villages, everyone was invited to participate. Data were collected by structured interviews and self-administered questionnaires conducted in both Greenlandic and Danish 123 J Gambl Stud according to the choice of the participant. The local hospitals or health center assisted with procuring facilities for the interviews. A total of 81 persons assisted with data collection and processing data. Questions about gambling were included in the self-administered questionnaire from 2006 and onwards. The sample for 2006–2010 included 3,893 Greenland Inuit. A total of 2,451 persons participated in the general survey (63 %) and 2,189 persons filled out the selfadministered questionnaire (56 %). The analyses were based on these 2,189 participants. In total 2012 of the 2,189 participants (92 %) answered at least one question about gambling. Gambling Behavior and Problem Gambling Respondents were asked how often they gambled during past year, how much time they spent each time they gambled and how much money they spent on gambling during past month regarding the lottery, bingo, cards/dice and slot machines. Problem gambling was measured using the lie/bet screen (Johnson and Hammer 1997), which has been validated in both treatment (Johnson and Hammer 1998) and community samples (Götestam et al. 2004). It is a two questions version of the 10 DSM-IV criteria for pathological gambling (American Psychiatric Association 2000). According to DSM-IV, a positive response to 5 or more of the 10 criteria is characterized as pathological gambling while three-four positive answers is defined as problem gambling. The lie/bet screen has been found valid to identify lifetime problem gamblers in a community sample, defined as those who responded positively to 5 or more of the 10 DSM-IV criteria combined with those who only responded positively to three-four of these criteria (Götestam et al. 2004). The short screen does not qualify to distinguish between pathological and problem gambling and it is important to stress, that the purpose of screening for problem gambling in a large health survey is to investigate an overall prevalence of how widely gambling is affecting a population, which is by no means comparable to a thorough clinical assessment of pathological gambling based on the DSM-IV criteria. The questions in the lie/bet screen are shown in Table 1. Positive answers to one or both questions for past year and previously were combined into a measure of lifetime problem gambling. We also included a question about self-rated problem gambling to see how well participants’ own perception corresponded with the lie/bet screen. Sociodemographic Variables Residence at age 10 was obtained from the interview and recoded into village or town. Family job type was determined from questions about job title of participant and spouse and recoded into hunters/fishermen and others. Formal education was determined from questions about highest school education attained and further vocational or academic education and recoded into primary school/high school only, short vocational education (less than 3 years), and longer vocational/academic education. Age was divided into four groups; 18–24, 25–34, 35–59 and 60? years. Social Transition Two measures of social transition were included. First measure was place of residence based on the differences in lifestyle and living conditions found between villages, towns and the capital. In order to supplement this measure we combined current place of 123 J Gambl Stud Table 1 Overview of key variables in the study. Frequency, percent and missing data. Greenland Inuit 2006–2010 Frequency (pct.) Total N Missing data 2,189 Gender Men Women 983 (44.9) 1,206 (55.1) Age groups 18–24 278 (12.7) 25–34 385 (17.6) 35–59 1,273 (58.2) 60? 253 (11.6) Problem gambling Lie/bet screen Q1: Have you ever lied (to family members, friends, co-workers or teachers) about how much you gamble, how much you have lost or how large your debt is? Yes, past year 37 (2.4) Yes, previously 100 (6.6) No/never gamble Yes, past year 22 (1.5) Yes, previously 73 (5.0) 1,456 733 1,500 689 1,361 (93.5) Selfrated problem gambling: Have you ever felt you had a gambling problem or were told so by others? Yes, past year 39 (2.6) Yes, previously 74 (4.9) No/never gamble 671 1,381 (91.0) Lie/bet screen Q2: Have you ever felt the need to bet more and more money (to reach the same level of exitement)? No/never gamble 1,518 1,387 (92.4) Social transition Place of residence 2,189 Nuuk 419 (19.1) Town 1,110 (50.7) Village 660 (30.2) Level of involvement in social transition (25–64 years) Hunters/fishermen in villages 1,750 25 1,985 204 161 (9.2) Other villagers 374 (21.4) Blue collar migrants in towns 172 (9.8) Other blue collar in towns 381 (21.8) Intermediate in towns 468 (26.7) Professionals in towns 194 (11.1) Traumatic childhood events Alcohol problems in childhood home No, never 822 (41.4) Yes, occasionaly 798 (40.2) Yes, often 365 (18.4) 123 J Gambl Stud Table 1 continued Frequency (pct.) Sexually abused as a child Yes No N Missing data 1,359 830 322 (23.7) 1,037 (76.3) Response to Q1 in the lie/bet screen was associated with gender (p \ 0.0001), age group (p \ 0.0001) and formal education (p = 0.0001). Response to Q2 in the lie/bet screen was associated with gender (p \ 0.0001), age group (p \ 0.0001) and formal education (p \ 0.0001). Response to question of selfrated problem gambling was associated with gender (p \ 0.0001), age groups (p \ 0.0001) and formal education (p = 0.003). Response to question about alcohol problem in childhood home was associated with gender (p \ 0.0001), age groups (p \ 0.0001) and formal education (p \ 0.0001). Response to question about sexual abuse as a child was associated with gender (p \ 0.0001), age group (p \ 0.0001), formal education (p \ 0.0001) and place of residence (p \ 0.0001) residence and childhood residence with formal education and family job type in a second measure that has previously been used to document changes in mental health and health behavior among Greenland Inuit (Bjerregaard and Dahl-Petersen 2011; Dahl-Petersen and Bjerregaard 2011). Six categories of social transition were defined as (A) hunters and fishermen in villages; (B) other inhabitants of villages; (C) blue collar migrants (inhabitants of towns, with no vocational education, having lived in villages at age 10); (D) other blue collar participants (inhabitants of towns, with no vocational education, having lived in towns at age 10); (E) intermediate (inhabitants of towns, with short vocational education); and (F) professionals (inhabitants of towns, with longer vocational or academic education). In order not to misclassify participants who had not yet finished their education and to minimize the proportion of participants outside the work force this measure only included those aged 25–64 years. Traumatic Childhood Events Alcohol related problems in childhood home and sexual abuse during childhood were included as traumatic childhood events. Participants were asked through the self-administered questionnaire if there were alcohol problems in their childhood home and whether anyone had forced any kind of sexual activity upon them as a child (before the age of 13). Statistical Analyses Statistical analyses were performed in IBM SPSS Statistics 19. Dichotomous variables were analyzed by bivariate logistic regression. In case of interaction between gender and outcome, analyses were performed separately for men and women. Differences in prevalence according to gender, age and social transition were tested using Pearson’s Chi2-test. Due to the sampling procedure, oversampling took place in certain strata while the participation rate was not similar according to age and gender. Accordingly, data were weighted for sampling strata by the weight procedure of SPSS in order to obtain national prevalence estimates. 123 J Gambl Stud Ethical Review The study was ethically approved by the Commission for Scientific Research in Greenland. Participants gave their written consent after being informed about the study orally and in writing. Results Characteristics of the study population according to key variables and analyses of response rates for specific questions are shown in Table 1. The majority of Greenland Inuit (80 %) engaged in at least one of four types of gambling past year and gender and age differences applied. The lottery was played by four out of five followed by bingo, cards/dice and slot machines (Table 2). A higher percentage of men compared to women had gambled on the lottery, cards/dice and slot machines during past year while more women than men had played bingo. Gambling behavior was associated with social transition measured as place of residence. Bingo was more common and played more frequently in villages and towns compared to the capital. People in villages gambled more frequently on cards/dice compared to the capital and in towns while the lottery and slot machines were much more common in the capital and in towns. Response to questions about gambling behavior varied according to sociodemographic differences. In general more men than women and more inhabitants from the capital compared to towns and villages had answered the questions. Further the odds ratio for answering decreased with age and increased with level of education (see note, Table 1). Gambling at least once a week on slot machines and cards/ dice was associated with past year problem gambling for both men and women, while playing bingo was not (Table 3). Using the lie/bet screen we found a past year prevalence for problem gambling of four percent among men and three percent among women. The lifetime prevalence was 16 % among men and 10 % among women (Table 4). The odds ratios for answering the questions in the lie/bet screen were higher among men than women and odds ratios for answering decreased with age and increased with level of education (see note, Table 1). A rather large percentage who reported gambling problems at some point in their life, did not report of any past year problems. At an overall level this was the case for 74 % among men and 71 % among women (results not tabulated). Among women the 1-year remission rate among those aged 18–34 years was 80–86 % compared to 64 % among those aged 35–59. Among men the 1-year remission rates among the 25–59 years old was 74–78 % compared to a lower 55 % in the youngest age group (18–24 years). Lifetime problem gambling was significantly associated with social transition and traumatic childhood events (Table 5). Hunters and fishermen in villages (A) and professionals (F) displayed the lowest odds ratio for lifetime problem gambling compared to other villagers and inhabitants of towns (B-E). These two groups represent each their end of the social transition scale. Among men, the odds ratio for lifetime problem gambling was higher in towns compared to the capital and in villages. Among those who often experienced alcohol problems in their childhood home the odds ratio for lifetime problem gambling was 3–4 times higher compared to those who never experienced such problems in their childhood home. Among women, being sexually abused as a child was also associated with lifetime problem gambling. When analyzed according to birth cohort the prevalence of lifetime problem gambling followed the pattern 123 J Gambl Stud Table 2 Prevalence of past year gambling* (at least once during past year) and frequent gambling* (at least once a month during past year) analyzed by type of gambling according to age and place of residence, stratified by gender. Percent. Greenland Inuit 2006–2010 Lottery Bingo Cards and dice Slot machines (Men = 827; women = 924; missing = 438) (Men = 848; women = 1,040; missing = 301) (Men = 807; women = 924; missing = 510) (Men = 786; women = 893; missing = 458) Past year Monthly Past year Past year Past year 18–24 years 41.1 19.6 23.6 3.6 30.9 10.9 32.4 9.3 25–34 years 74.3 38.2 37.0 16.3 44.1 15.6 27.3 9.1 5.9 Monthly Monthly Monthly Men Age groups 35–59 years 80.5 44.2 41.8 20.4 32.1 8.3 25.4 60? years 54.9 35.3 29.7 16.8 16.5 3.3 9.8 6.5 0.011 0.011 0.454 p value \0.0001 \0.0001 0.001 \0.0001 \0.0001 Place of residence Nuuk 78.5 43.9 16.5 4.9 31.3 10.6 31.7 8.2 Towns 68.3 37.3 43.5 22.6 34.6 10.9 21.6 7.3 8.7 45.0 15.9 37.8 20.6 6.9 Villages p value All Men 39.7 \0.0001 \0.0001 \0.0001 \0.0001 0.358 \0.0001 \0.0001 9.9 25.6 1.6 0.003 69.6 37.5 36.4 16.2 32.5 7.1 18–24 47.4 13.6 41.8 16.4 27.6 9.8 17.1 0.7 25–34 58.1 21.1 50.7 23.5 26.7 10.3 11.1 1.6 Women Age groups 35–59 68.5 25.4 56.2 33.0 24.0 8.3 15.1 4.4 60? 51.4 25.4 57.6 43.0 20.6 11.8 5.7 3.8 0.103 0.062a p value \0.0001 0.018 \0.0001 \0.0001 0.612 0.718 Place of residence Nuuk 75.8 28.3 33.7 12.8 19.3 6.7 21.6 Towns 59.6 22.2 61.0 37.1 23.7 9.1 9.8 2.0 Villages 21.4 4.3 67.8 28.0 43.6 19.0 3.2 0.5 p value All women \0.0001 60.8 \0.0001 \0.0001 22.2 51.9 \0.0001 \0.0001 29.1 24.3 \0.0001 \0.0001 8.9 13.7 5.7 0.004 2.8 The numbers reported for age groups are weighted for regional differences in the sample. The numbers reported according to place of residence are weighted for age differences in the sample. The overall prevalence for men and women are weighted for both regional and age differences in the sample * Response regarding gambling on the lottery was associated with gender (p \ 0.0001), age group (p \ 0.0001), level of education (p \ 0.0001) and place of residence (p \ 0.0001). Response regarding playing bingo was associated with age group (p \ 0.0001), level of education (p \ 0.0001) and place of residence (p = 0.005). Response regarding gambling on cards/dice was associated with gender (p \ 0.0001), age group (p \ 0.0001), level of education (p \ 0.0001) and place of residence (p \ 0.0001). Response regarding frequency of gambling on slot machines was associated with gender (p \ 0.0001), age groups (p \ 0.0001); Level of education (p \ 0.0001); Place of residence (p \ 0.0001) a Expected count less than 5 123 J Gambl Stud Table 3 Past year problem gambling according to weekly gambling activity during past year (at least once a week) among men and women. Adjusted for age and place of residence. Odds Ratio (OR) with 95 % Confidence Interval (C.I.). Greenland Inuit 2006–2010 Weekly gambling activity during past year Men OR [C.I. 95 %] Women p value OR [C.I. 95 %] p value The lottery (men = 827; women = 924) Less than once a week (ref.) At least once a week 1.03 [0.28–3.84] (ref.) 0.964 9.25 [2.37–36.00] 0.837 2.04 [0.60–6.94] 0.001 Bingo (men = 848; women = 1,040) Less than once a week (ref.) At least once a week 0.87 [0.22–3.40] (ref.) 0.106 Cards/dice (men = 807; women = 924) Less than once a week (ref.) (ref.) At least once a week 10.27 [3.44–30.64] \0.0001 7.16 [1.73–29.65] 0.007 Slot machines (men = 786; women = 893) Less than once a week (ref.) At least once a week 5.94 [1.45–24.29] (ref.) 0.013 20.11 [1.76–229.75] 0.016 of both alcohol problems in childhood home and sexual abuse during childhood with the highest prevalence found for the generations born in the 70s (Figure 1). Compared to the lifetime prevalence of problem gambling identified by the lie/bet screen fewer persons felt they had ever had a gambling problem or had been told so by others (7.5 %, Table 1). No difference was found between men and women. Discussion Gambling behavior and problem gambling among Greenland Inuit were associated with social transition measured as residence in the capital, town or village and significant differences according to age and gender were found. This association was further elaborated by a significant association between lifetime problem gambling and social transition measured as place of residence combined with childhood residence in town (including the capital) or village as well as formal education and family job. Lifetime problem gambling was also associated with traumatic events during childhood. The prevalence for past year gambling was higher among men than women for all types of gambling but bingo. This corresponded well with a higher prevalence of problem gambling among men compared to women although only significant for lifetime problem gambling. Also a rather high 1-year remission rate was found among lifetime problem gamblers suggesting that one does not necessarily have a gambling problem forever. Compared to findings from the Scandinavian countries Denmark, Sweden and Norway the prevalence of both past year and lifetime problem gambling among Inuit in Greenland was 4–6 times higher (Bonke and Borregaard 2009). However these Scandinavian prevalence surveys used the revised South Oaks Gambling Screen (SOGS-R) (Lesieur and Blume 1993) and the NORC DSM Screen for Gambling Problems (NODS) (Gerstein et al. 1999) to identify past year and lifetime problem gamblers and the results are therefore not 123 J Gambl Stud Table 4 Prevalence of past year and lifetime problem gambling (PG) among men and women* according to age and social transition (place of residence). p value based on Chi2-test. Unadjusted percent. Greenland Inuit 2006–2010 % past year PG (freq.) p value % lifetime PG (freq.) p value Men Age group 18–24 9.5 (9) 21.1 (20) 25–34 5.6 (7) 21.8 (27) 35–59 3.0 (13) 60? 1.2 (1) 13.8 (59) 0.013 11.8 (10) 0.053 Social transition (place of residence) Nuuk 0.8 (1) Towns 5.3 (21) Villages 3.7 (8) Men total 11.4 (14) 19.3 (76) 0.081 12.0 (26) 4.1 (30) 15.8 (116) 18–24 1.7 (2) 8.6 (10) 25–34 1.2 (2) 0.020 Women Age group 35–59 4 (19) 60? 0 (0) 9.3 (15) 11.2 (53) 0.104 3.3 (2) 0.249 Social transition (place of residence) Nuuk 1.1 (2) 8.4 (15) Town 3.4 (14) 10.5 (43) Villages 3.2 (7) Women total 2.8 (23) 0.286 10.0 (22) 0.735 9.9 (80) Men = 733; Women = 809 * Overall difference between men and women for past year problem gambling (Chi2-test; p = 0.179) and lifetime problem gambling (Chi2-test; p \ 0.001) directly comparable. Götestam et al. (2004) reported a 0.54 % prevalence of lifetime problem gambling based on the lie/bet screen in a community sample of adults (18?) in Norway. This prevalence is actually a little lower than the prevalence found by Lund and Nordlund (2003) in Norway in the same survey year based on the NODS as a screening tool suggesting the lie/bet screen did not overestimate the lifetime prevalence in the Norwegian population despite its brief character. Furthermore the Danish Health Interview Survey from 2005 (Ekholm et al. 2009) included the lie/bet screen and found a lifetime prevalence for problem gambling of 2.6 % among those aged 16? (unpublished results). This prevalence was a little higher than the one found in the Danish Gambling Survey by Bonke and Borregaard (2006) mentioned above, where the SOGS-R identified 1.7 % lifetime problem gamblers and the NODS identified 0.7 % lifetime problem gamblers among adults (18?). This suggests the lie/bet screen slightly overestimated the lifetime prevalence in the Danish population compared to both NODS and SOGS-R. Despite methodological differences, the lifetime prevalence found among Greenland Inuit seems high. Given the many similarities in gambling availability and legislation between Denmark and Greenland, it is alarming to find a markedly higher lifetime prevalence of 123 J Gambl Stud Table 5 Lifetime problem gambling according to social transition and traumatic events during childhood. Adjusted analyses. Odds ratio (OR) with 95 % Confidence Intervals (C.I.). Greenland Inuit 2006–2010 Men OR [C.I.] Women p value OR [C.I.] Total p value OR [C.I.] p value Social transition Place of residence (Men = 733; Women = 809) 0.695 0.021 Nuuk (ref.) Town 1.86 [1.01–3.44] 0.047 1.31 [0.71–2.42] (ref.) 0.396 Villages 1.05 [0.52–2.10] 0.891 1.23 [0.62–2.49] 0.532 Level of involvement in social transition (25–64 years only, N = 1,237) 0.023 Hunters/fishermen in villages (ref.) Other villagers 1.88 [0.83–4.25] 0.132 Blue collar migrants in towns 1.60 [0.62–4.10] 0.329 Other blue collar in towns 2.56 [1.16–5.64] 0.020 Intermediate in towns 2.22 [1.02–4.85] 0.046 Professionals in towns 0.81 [0.29–2.23] 0.679 Traumatic events during childhood (men = 549; women = 509) Sexual abuse during childhood No (ref.) Yes 1.53 [0.80–2.90] Alcohol problems in childhood home (ref.) 0.196 2.02 [1.07–3.81] 0.001 0.030 0.002 Never (ref.) (ref.) Occasionally 1.27 [0.70–2.31] 0.432 1.42 [0.66–3.08] 0.374 Often 3.12 [1.65–6.20] 0.001 3.64 [1.68–7.91] 0.001 Model 1 included place of residence stratified by gender and adjusted for age group. Model 2 included level of involvement in social transition adjusted for gender and age group. No interaction was found between gender and level of involvement in social transition and the analysis was thus carried out for men and women together. Model 3 included sexual abuse in childhood and alcohol problems in childhood stratified by gender and adjusted for age group, level of education and place of residence Bold values indicate p \ 0.05 problem gambling among Greenland Inuit. A higher prevalence of problem gambling among ethnic minorities and indigenous populations compared to their non-indigenous neighbors has been found in other studies (Abbott and Volberg 2000; Shaffer et al. 2004; Wardle et al. 2011). However there is an important difference between a high prevalence of problem gambling in a smaller often marginalized indigenous population constituting a minority in a larger population compared to a high prevalence in an indigenous population that constitute the majority in their own country, which is the case for Inuit in Greenland. 123 J Gambl Stud 40 35 30 25 20 15 10 5 0 -1954 1955-1959 1960-1964 1965-1969 1970-1974 1975-1979 1980-1985 1985- Often experienced alcohol problems in childhood home Lifetime problem gambling Sexually abused as a child Fig. 1 Prevalence of alcohol problems in childhood home, lifetime problem gambling and sexual abuse in childhood according to birth cohort. Unadjusted percent. Greenland Inuit 2006–2010. Chi2-test for difference between birth cohorts: Alcohol problems (p \ 0.0001) (N = 1,985); Lifetime problem gambling (p = 0.017) (N = 1,542); Sexual abuse (p \ 0.0001) (N = 1,359) The associations found with social transition and childhood conditions thus suggest that the high prevalence could be related to the ongoing rapid change and the social consequences of such changes rather than marginalization. The association between gambling behavior and social transition was reflected in a preference for the lottery and slot machines in the capital and for bingo and cards/dice in towns and villages. This indicates a mix of patterns between modern games popular in contemporary Scandinavia and games found to be traditionally popular among Inuit in Nunavik and First Nations (Muckle et al. 2007; Papineau 2010). The preference for bingo, which was played by 60–70 % of the women in towns and villages, but only by 32 % of the women in the capital, illustrated this pattern. Despite the large influence bingo presumably has on daily life, no association between weekly gambling on bingo and past year problem gambling was found. It is however important to keep in mind, that the lie/bet screen and other screens developed to identify problem gamblers might not be suited to identify the potential social consequences of gambling in families and communities. In contrast to bingo weekly gambling on cards/dice and slot machines was significantly associated with higher odds ratios for past year problem gambling. These games typically involve excitement and are fundamentally different from bingo and most forms of the lottery. The distinct characteristics of the different types of gambling might explain the differences in associations between weekly gambling and past year problem gambling. Although the association between weekly gambling on slot machines and past year problem gambling is in accordance with a general consideration that electronic gaming is the most addictive form of gambling, the empirical evidence supporting this perception is inconclusive (Dowling et al. 2005). The association between problem gambling and social transition was reflected in a higher prevalence of lifetime problem gambling in towns compared to villages and the capital among men and lower odds ratios for lifetime problem gambling among both hunters and fishermen in villages as well as among professionals in towns compared to other villagers, blue collar workers in towns and persons with a short vocational education 123 J Gambl Stud in towns. People in towns in Greenland might generally be considered to have the most difficult position in the ongoing social transition because they are caught in the middle of the more traditional life in the villages and the modern life in the capital. Differences in odds ratios for lifetime problem gambling between hunters and fishermen in villages compared to other villagers and between professionals in towns compared to the three less educated or unskilled groups in towns add to the understanding of the complex association between social transition and gambling problems among Greenland Inuit. Hunters and fishermen are naturally integrated in village life where traditional Inuit lifestyle is still prevalent as are professionals in towns where life reflects the modern Greenlandic Society. In contrast village life is more challenging if you are not hunting and fishing because very few educational and occupational opportunities are available. So is life in a larger town if you are not skilled or well educated as expectations and demands for qualifications rise with the level of specialization in modern society. The prevalence of alcohol problems in childhood, sexual abuse and lifetime problem gambling analyzed according to birth cohorts illustrated how the generation born in the 70s experienced the highest prevalence across all three outcomes. This generation grew up during the 70s and the 80s when the alcohol consumption in Greenland was at its highest (Statistics Greenland 2002). These were also decades where extensive infrastructural development occurred, which transformed Greenland from a traditional hunting society into a modern economy where most people depended on earning wages (Young and Bjerregaard 2008). Based on these observations the high prevalence of alcohol problems in childhood home and sexual abuse in childhood during these years seems linked to social transition. Life style changes, social change, and changes in society and the environment have been documented as major determinants of health among the northern indigenous populations (Bjerregaard et al. 2004; Young and Bjerregaard 2008). Many causes of social pathologies such as alcohol misuse have been postulated at the individual, family and community level and different explanations focus on the stress of rapid social change and the inadequacy of traditional conflict resolution behaviors in the new, more urbanized environments (Kirmayer et al. 2000; Lethi et al. 2009). However a previous study among Greenland Inuit has suggested that successful integration into the modern Greenlandic society might explain why some groups within the population have better mental health compared to others (Bjerregaard and Curtis 2002). Other studies have found an association between traumatic childhood events and lifetime problem gambling—especially among pathological gamblers in treatment (Hodgins et al. 2010; Kausch et al. 2006; Petry and Steinberg 2005; Wardman et al. 2001). Childhood disturbance as a cause of emotional vulnerability has been suggested to constitute a potential pathway for the development of problem and pathological gambling (Blaszczynski and Nower 2002). Given the high prevalence of alcohol problems in families, violence and sexual abuse in most circumpolar indigenous communities (Kruse et al. 2007), targeted prevention programs concerning problem gambling should take the complexity of these issues into account. Future research should look into why some population groups are caught between traditional and modern way of life while others integrate well and thereby contribute to the understanding of causes of both mental and physical health inequalities in indigenous populations. Prospective studies are needed to investigate whether causality between traumatic childhood events and problem gambling later in life can be established. Finally we need to gain a better understanding of why undergoing rapid social transition has led to an increase in social pathologies across indigenous populations in order to prevent a further increase in the future. 123 J Gambl Stud A particular strength of the study is the large representative sample of an indigenous population, which is a majority in its country. This allowed us to investigate differences according to social transition within the population. Another strength is the various topics included in the general health survey that provided us with the opportunity to include traumatic childhood events in the study. A weakness of the study is the social gradient in the response to questions about problem gambling and traumatic childhood events. It is likely this has led to an underestimation of the prevalence. We found the odds ratio for answering the lie/bet screen was significantly higher among men, the younger age groups and those with an academic degree. We also checked to see if it made a difference whether the respondents had chosen to answer the questions in Danish or Greenlandic, but this was not the case. Based on the existing data we were not able to further asses why a relatively large proportion of the participants chose not to answer the lie/bet screen or chose to answer one of the two questions but not the other. The number of missing data on the lie/bet screen is larger than the number of missing data on the questions regarding different types of gambling, which suggests people are more likely to answer questions about gambling activities rather than gambling problems. Whether this has to do with participants not wanting to answer questions about gambling problems they might have or with the fact that it is tempting to skip a question in a long questionnaire if it seems irrelevant to you personally, should be investigated through future qualitative methodological studies. Such insights would be valuable for future prevalence studies. Another weakness is the fact that the lie/bet screen has only been used in few other studies. This makes it difficult to compare our results with other prevalence studies. Furthermore comparisons of the lie/bet screen with peoples own perception suggests either a high level of denial among lifetime problem gamblers or a questionable validity of the short screen. It is likely the lie/bet screen captures very mild gambling problems along with more serious ones. 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Harmful alcohol use and frequent use of marijuana among lifetime problem gamblers and the prevalence of cross-addictive behaviors among Greenland Inuit – evidence from the cross-sectional Inuit Health in Transition Greenland Survey 2006-2010; International Journal of Circumpolar Health, 2013, 72:19551. doi: 10.3402/ijch.v72i0.19551. ORIGINAL RESEARCH ARTICLE æ Harmful alcohol use and frequent use of marijuana among lifetime problem gamblers and the prevalence of crossaddictive behaviour among Greenland Inuit: evidence from the cross-sectional Inuit health in transition Greenland survey 20062010 Christina Viskum Lytken Larsen1*, Tine Curtis2 and Peter Bjerregaard1 1 National Institute of Public Health, University of Southern Denmark, Denmark; 2Local Government Denmark, Denmark Background and objectives. Public health research has pointed to alcohol and substance abuse as the most significant public health challenges in Greenland with the negative impact on families and communities that entail, but few studies have investigated the role of problem gambling as addictive behaviour among Inuit. The objectives of the present study were to investigate (a) the association between lifetime problem gambling and harmful alcohol use as well as frequent use of marijuana and (b) the prevalence of cross-addictive behaviour among Greenland Inuit. Design. A representative cross-sectional study among Greenland Inuit (n 2,189). Data was collected among adults (18) in 8 towns and 13 villages in Greenland from 20062010. Lifetime problem gambling, harmful alcohol use and frequent use of marijuana were measured through a self-administered questionnaire. Results. The odds ratio for harmful alcohol use and frequent use of marijuana was significantly higher among lifetime problem gamblers compared to non-problem gamblers/non-gamblers. One or more addictive behaviours were present among more than half of the men (53%) and one third of the women (37%), and the co-occurrence of lifetime problem gambling with either harmful alcohol use, frequent use of marijuana or both was found among 12.2% of men and 3.7% of women. The prevalence of one or more addictive behaviours was 44% in households with children. Conclusions. For lifetime problem gamblers, the gambling problems were more often than not combined with harmful alcohol use, frequent use of marijuana or both especially among men. The high prevalence of addictive behaviours in households with children indicates that many families are presently affected negatively by alcohol, gambling and marijuana. This suggests that pathological gambling should be included systematically in future public health strategies, treatment programs and interventions in Greenland. Keywords: problem gambling; indigenous health; social pathologies; addictive behaviour; Inuit Received: 15 August 2012; Revised: 24 December 2012; Accepted: 24 December 2012; Published: 15 March 2013 ublic health research has pointed to alcohol and substance abuse as the most significant public health challenge in Greenland. The negative consequences of especially alcohol problems reach far into the lives of communities, families and children. It is well known that use of alcohol and marijuana is often P combined, but few studies have investigated how gambling problems might be included in a pattern of crossaddictive behaviours among Greenland Inuit. In recent years, pathological gambling has become an issue of increasing concern in Greenland (1). For the majority, gambling is a harmless activity, but for some Int J Circumpolar Health 2013. # 2013 Christina Viskum Lytken Larsen et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License (http://creativecommons.org/licenses/by-nc/3.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Citation: Int J Circumpolar Health 2013, 72: 19551 - http://dx.doi.org/10.3402/ijch.v72i0.19551 1 (page number not for citation purpose) Christina Viskum Lytken Larsen et al. gambling becomes a disorder with a negative impact on their personal lives, families and the communities they live in (2). Little research has been conducted in this area among Greenland Inuit, which might explain why public health programs and intervention strategies have not yet taken pathological gambling into account. In the Inuit Health in Transition Greenland survey 20062010, we found the lifetime prevalence for problem gambling to be 9% among women and 16% among men, and the gambling patterns reflected a mix of modern games popular in contemporary Scandinavia and games found to be traditionally popular among Inuit in Nunavik and First Nations (3). The high prevalence of lifetime problem gambling reflects the increase in social pathologies Greenland has experienced during the past 60 years. The rapid social transition Greenland Inuit have gone through has been accompanied by a high prevalence of addictive behaviours (4). Although the average alcohol intake has decreased since the 1980s, where the alcohol consumption was at its highest (5), a drinking pattern dominated by binge drinking persists as a major cause of social and health problems in Greenland. Today, Greenland is still struggling with the negative consequences for the generations who grew up with alcohol problems in their childhood home such as suicidal behaviour and a high prevalence of violence and sexual abuse (6,7), and, in recent years, increased political attention has been given to improving the lives of children and families. The use of hard drugs has never been a problem in Greenland. Given the geographical isolation, the police have managed to prevent drugs, other than marijuana, from entering Greenland. The issue of substance abuse among Greenland Inuit this primarily regards the use of marijuana. Several international studies have found problem gambling to be associated with alcohol and substance use as well as mental disorders, but most of these studies have been conducted in a clinical context among pathological gamblers in treatment, and their findings cannot easily be generalised to problem gamblers in the general population. A recent review evaluated the prevalence of comorbid disorders among problem and pathological gamblers in population surveys and pointed to an elevated prevalence of both substance and alcohol use disorders among problem and pathological gamblers compared to non-problem gamblers across studies (8). However, none of these studies had been conducted among indigenous populations, where the prevalence of addictive behaviours is high. The objectives of the present study were, thus, to investigate (a) the association between lifetime problem gambling and harmful alcohol use as well as frequent use of marijuana and (b) the prevalence of crossaddictive behaviour among Greenland Inuit. We hypothe- 2 (page number not for citation purpose) sised that lifetime problem gambling was associated with a higher prevalence of harmful alcohol use and frequent use of marijuana, compared to the prevalence among non-problem gamblers and those who never gambled. Material and methods Data and sample size Data was derived from the cross-sectional Inuit Health in Transition Greenland Survey 20052010. The study was a population-based general health study among adults (18). A full methodological report of the study is published elsewhere (9). Greenland was divided into 12 strata based on geography and community size. From each region, a number of towns and villages were selected for the study. A random sample was drawn from the central population register to obtain around 300 participants from the towns included. In the selected villages, everyone was invited to participate. Data were collected by an interviewer-based questionnaire combined with a self-administered questionnaire containing the more sensitive and personal questions, which were believed not to be suited for the face-to-face interview. The questions regarding problem gambling, alcohol use and use of marijuana were all included in the self-administered questionnaire. Questions about gambling were included in the self-administered questionnaire from 2006 and onwards. The 20062010 sample included 3,893 Greenland Inuit. A total of 2,451 persons participated in the general survey (63%), and 2,189 persons filled out the self-administered questionnaire (56%). The analyses were based on these 2,189 participants. In total, 2,012 of the 2,189 participants (92%) answered at least one question about gambling. Despite Greenland’s large geographical size, its total population is only about 57,000, of whom 90% are ethnic Greenlanders (Inuit). Genetically, Greenlanders are Inuit (Eskimos) with a mixture of European, mainly Scandinavian, genes. They are closely related to the Inuit/ Iñupiat in Canada and Alaska and, somewhat more distantly, to the Yupiit of Alaska and Siberia (10). Lifetime problem gambling, harmful alcohol use and frequent use of marijuana The questions about pathological gambling in this study were a small part of a larger health survey, which forced us to use a short screen. Problem gambling was measured using the Lie/Bet Questionnaire (see Table II) originally suggested by Johnson and Hammer (11) and later validated by both Johnson and Hammer (12) and Götestam et al. (13). The Lie/Bet Questionnaire is a two-question version of the 10 DSM-IV criteria for pathological gambling (2). According to DSM-IV, a positive response to 5 or more of the 10 criteria is characterised as pathological Citation: Int J Circumpolar Health 2013, 72: 19551 - http://dx.doi.org/10.3402/ijch.v72i0.19551 Cross-addictive behaviour among Greenland Inuit gambling, while three to four positive answers are defined as problem gambling. The lie/bet screen has been found valid to identify lifetime problem gamblers, defined as those who responded positively to 5 or more of the 10 DSMIV criteria in a combined group with those who responded positively to only three to four of these criteria (13). The short screen cannot distinguish between pathological and problem gambling. Respondents were asked whether or not they had lied to friends and family about their gambling activities, and whether or not they had felt a need to increase bets in the past year or previously in life. Positive answers for the past year and previously were combined for a prevalence of lifetime problem gambling, that is problem gambling that had occurred at some point in life. Analyses are based on lifetime gamblers as opposed to past year gamblers in order include enough individuals to be able to analyse subgroups in the sample. Nonproblem gamblers and those who never gamble are collapsed into one group in the analyses. When mentioned in the text, they are called non-problem gamblers, although they include a small group who never gamble. Harmful alcohol use was measured by the modified CAGE-test: CAGE-C. It is a simple screening tool suited for identifying alcohol problems in populations with a high prevalence of at-risk drinkers. The original CAGE test was based on a 4-item questionnaire and measured harmful alcohol use in a lifetime perspective (14). However, the validity of the original questionnaire outside a clinical context has been questioned (15), and the sensitivity of the test has been criticised in several studies (16,17). The 6-item questionnaire CAGE-C was suggested by Zierau et al. in 2005 (18) and validated against a diagnostic interview based on ICD-10 (19) and DSMIII R (20) criteria. The questionnaire (Fig. 1) has been used to assess harmful alcohol intake among Greenland Inuit in an earlier study (21). The modified CAGE-test was included in the self-administered questionnaire. It measures harmful alcohol use in a past year perspective and includes a question regarding the number of days per week of alcohol use and a question concerning alcohol intake on weekdays outside meals. CAGE positives were defined by a positive answer in two or more of questions 14 and 6, or one positive answer in question 14 and 6, in addition to alcohol intake on 4 or more days per week. Frequent use of marijuana in the past year was measured through two questions in the self-administered questionnaire. Participants were asked if they had ever smoked marijuana. Those who answered ‘‘yes, once or a few times’’ or ‘‘yes, several times’’ were asked how often they had smoked marijuana in the past year. Those who had tried smoking marijuana and additionally answered that they had smoked at least one to three times a month in the past year were categorised as past-year frequent users of marijuana. Those who had never tried to smoke and those who had smoked less than once a month in the past year were categorised together as non-frequent users/non-users. Socio-demographic variables Age, place of residence and formal education were included as socio-demographic variables. To ensure enough observations, age groups were collapsed into two groups of 1834 years and 35 years. Formal education was determined from questions about highest school education attained and further vocational or academic education, and recoded into primary school/ high school only, short vocational education (less than 3 years), and longer vocational/academic education. Information on the socio-demographic variables was obtained through the interviewer-based questionnaire. Place of residence was divided between the capital Nuuk, towns and villages. Greenland has a total of 80 communities all located on the coast. A town is defined historically as the largest community in each of 17 districts. In 2010, the population of Nuuk was 15,469, the population of the towns varied between 469 and 5,460, while that of the villages varied from less than 10 to around 550. In the towns are located district school(s), a health centre or hospital, church, district administration and main shops. These institutions are absent or present to a much smaller extent in the villages. The isolated populations in the villages and smaller towns face the largest challenges with limited job and recreational opportunities. In contrast to these, the capital, Nuuk, with its more than 15,000 inhabitants is a modern town reflecting contemporary Scandinavian lifestyle with a wide range of educational, occupational and recreational possibilities (22). Alcohol problems in the childhood home Traumatic events during childhood have been found to be associated with problem gambling in previous studies (23). Therefore, logistic regressions were adjusted for alcohol problems in childhood in the analyses of the association between lifetime problem gambling, harmful alcohol use and frequent use of marijuana. Participants were asked through the self-administered questionnaire if there were alcohol problems in their childhood home (never; yes, occasionally; yes, often). Statistical analyses Differences between problem gamblers and non-problem gamblers regarding harmful alcohol use and frequent use of marijuana according to gender, age group and place of residence were tested with chi-square test. Prevalence estimates were weighted for regional and age differences in the sample. Analyses were done by logistic regression stratified for gender. Results are reported as odds ratios (OR) with a 95% confidence interval (CI). Both adjusted and unadjusted ORs are reported. Citation: Int J Circumpolar Health 2013, 72: 19551 - http://dx.doi.org/10.3402/ijch.v72i0.19551 3 (page number not for citation purpose) Christina Viskum Lytken Larsen et al. Ethical review The study was ethically approved by the Commission for Scientific Research in Greenland. Participants gave their written consent after being informed about the study orally and in writing. group (pB0.0001) and place of residence (pB0.0001). In general, the odds ratio for having answered the questions was higher among men than women, and among inhabitants from the capital Nuuk compared to inhabitants from towns and villages. The odds ratio decreased with age and increased with level of education. Results Socio-demographic variation in response The variables included in the study are displayed in Table I. Initially the response rate for the key variables included was analysed for associations with sociodemographic variables (results not tabulated). Response to questions regarding problem gambling was associated with gender (p B0.0001), formal education (p B0.0001) and age group (p B0.0001). Response to questions about harmful alcohol use was associated with gender (p0.012), formal education (p0.004), age group (pB0.0001) and place of residence (pB0.0001). Response to questions about use of marijuana was associated with gender (pB0.0001), formal education (pB0.0001), age Table I. Overview of variables included. Frequency, valid percent, N, missing data and socio-demographic associations in response rates for the variables regarding problem gambling, alcohol use and marijuana Frequency (%) Total Men Women Age groups 1824 years 0 2,189 0 2,189 0 278 (12.7) 385 (17.6) 1,273 (58.2) 253 (11.6) Place of residence Town Village 2,189 1,206 (55.1) 2534 years Nuuk Missing 983 (44.9) 3559 years 60 N 419 (19.1) 1,110 (50.7) 660 (30.2) Lifetime problem gambling 1,542 647 1,599 590 1,833 356 (Lie/bet screen) Yes 196 (12.7) No 1,346 (87.3) Harmful alcohol use past year (CAGE-C) Yes No 521 (32.6) 1,078 (67.4) Frequent use of marijuana past year Yes 250 (13.6) No 1,583 (86.4) Response rates were analysed by logistic regression for associations with gender, age, place of residence and level of education. Greenland Inuit 20062010. 4 (page number not for citation purpose) Harmful alcohol use Lifetime problem gambling was significantly associated with a harmful use of alcohol among men, but not among women (Table II), and the odds ratio for harmful alcohol use was twice as high for male lifetime problem gamblers as for non-problem gamblers (both unadjusted and adjusted). The prevalence of harmful alcohol use among lifetime problem gamblers compared to nonproblem gamblers was significantly higher for those aged 35. Among lifetime problem gamblers, the prevalence of harmful alcohol use increased with age, while decreasing with age among the non-problem gamblers (men and women). Harmful alcohol use was more prevalent among lifetime problem gamblers compared to non-problem gamblers in towns and villages, but not in the capital (men only). Frequent use of marijuana Lifetime problem gambling was significantly associated with a frequent use of marijuana (Table II). Women displayed an odds ratio for frequent use of marijuana almost 3 times higher among lifetime problem gamblers compared to non-problem gamblers (both unadjusted and adjusted). The prevalence of frequent use of marijuana was significantly higher among lifetime problem gamblers in both age groups compared to non-problem gamblers. There was a significantly higher prevalence of frequent use of marijuana among lifetime problem gamblers compared to non-problem gamblers in the capital and towns, but not in the villages. Cross-addictive behaviours In Fig. 2, the different combinations of lifetime problem gambling, harmful alcohol use and frequent use of marijuana were analysed for men and women (pB0.0001). A total of 8 different categories were constructed, that is 1) a category of no addictive behaviour, where neither lifetime problem gambling, frequent use of marijuana or harmful alcohol use were present; 2) lifetime problem gambling only; 3) harmful alcohol use only; 4) frequent use of marijuana only; 5) lifetime problem gambling combined with frequent use of marijuana; 6) lifetime problem gambling combined with harmful alcohol use; 7) frequent use of marijuana combined with harmful alcohol use; and, finally, 8) lifetime problem gambling combined with both frequent use of marijuana and harmful alcohol use. Fifty three percent of men and 37% of women were either lifetime problem gamblers, used marijuana Citation: Int J Circumpolar Health 2013, 72: 19551 - http://dx.doi.org/10.3402/ijch.v72i0.19551 Cross-addictive behaviour among Greenland Inuit Table II. Prevalence of harmful alcohol use and frequent use of marijuana in past year among lifetime problem gamblers compared to non-problem gamblers/non-gamblers according to gender, age and place of residence Harmful alcohol use past year (CAGE-C) Frequent use of marijuana past year Non-problem Lifetime problem gamblers gamblers/ non-gamblers Unadjusted 2.24 (1.443.48) Adjusted for age and place of 2.26 (1.453.54) 2.14 (1.353.41) Non-problem p Lifetime problem gamblers gamblers/ non-gamblers p 1 (ref.) B0.0001 1.74 (1.072.83) 1 (ref.) 0.027 1 (ref.) B0.0001 1.73 (1.062.85) 1 (ref.) 0.030 1 (ref.) 0.001 1.56 (0.942.59) 1 (ref.) 0.089 34.4% (178) 0.001 16.8% (94) B0.0001 Men Odds ratio (95% CI) residence Adjusted for age, place of residence and alcohol problems in childhood home Percent (N) All men 49.6% (54) 40.6% (27) Age groups 1834 years 34.1% (17) 45.3% (57) 0.207 40.0% (11) 20.4% (30) 0.007 58.7% (37) 29.1% (121) B0.0001 40.3% (16) 15.2% (41) B0.0001 40.0% (5) 27.2% (28) 0.303* 53.3% (34) 73.1% (15) 36.4% (91) 41.7% (59) 0.008 0.005 1.58 (0.902.77) 1.59 (0.902.81) 1 (ref.) 1 (ref.) 0.115 0.109 2.75 (1.445.25) 2.98 (1.545.79) 1 (ref.) 1 (ref.) 0.002 0.001 1.26 (0.702.26) 1 (ref.) 0.442 2.69 (1.355.34) 1 (ref.) 0.005 24.3% (156) 0.189 28.0% (14) 11.9% (59) 0.001 41.2% (7) 23.3% (7) 19.5% (30) 8.0% (29) 0.034* 0.001* Nuuk 44.8% (10) 17.7% (60) 0.001 Town 25.9% (45) 13.2% (171) 0.001 Village 7.0% (20) 9.2% (103) 0.631* 35 years Place of residence Nuuk Town Village Women Odds ratio (95% CI) Unadjusted Adjusted for age and place of residence Adjusted for age, place of residence and alcohol problems in childhood home Percent (N) All women 34.1% (21) Age groups 1834 years 21.4% (6) 30.5% (66) 39.4% (15) 23.0% (90) 0.474 0.035 Nuuk 36.4% (5) 21.4% (32) 0.256* Town 39.1% (11) 26.9% (80) 0.210 Village 26.7% (5) 28.4% (44) 0.890* 35 years Place of residence Total Percent (N) Place of residence *Expected count less than 5. Analysis of frequent use of marijuana according to place of residence was not stratified by gender because this resulted in too few individuals in each group. Greenland Inuit 20062010. Logistic regressions were stratified according to gender. Unadjusted and adjusted odds ratios (OR) with 95% confidence intervals (CI). p50.05 values are present in bold. frequently, and/or had harmful alcohol use, or different combinations of the three. Harmful alcohol use was the most prevalent addictive behaviour among both men and women. Harmful alcohol use and frequent use of marijuana co-occurred with lifetime problem gambling among 12.2% of the men and 3.7% of the women. In comparison, harmful alcohol use and frequent use of marijuana co-occurred among 12.6% of men and 6.5% of women. Cross-addictive behaviour was found among 20.4% of men and 8.6% of women. For 4.4% of men Citation: Int J Circumpolar Health 2013, 72: 19551 - http://dx.doi.org/10.3402/ijch.v72i0.19551 5 (page number not for citation purpose) Christina Viskum Lytken Larsen et al. The lie/bet screen questionnaire: Positive answers for past year and previously were combined for a prevalence of lifetime problem gambling, i.e. problem gambling that has occurred at some point in life. 1 Have you ever lied (to family members, friends, co-workers or teachers) about how much you gamble, how much you have lost or how large your debt is? Yes, past year/ Yes, previously/ No/ Never gamble 2 Have you ever felt the need to bet more and more money (to reach the same level of exitement)? Yes, past year/ Yes, previously/ No/ Never gamble The CAGE-C test questionnaire: A positive result was defined as two or more positive answers in questions 1-4 and 6, or one positive answer in questions1-4 and 6 in addition to alcohol intake on 4 or more days per week 1 Have you, within the past year, felt that you should cut down on your drinking? Yes/No 2 Have people, within the past year, annoyed you by criticizing your drinking? Yes/No 3 Have you, within the past year, felt bad or guilty about your drinking? Yes/No 4 Have you, within the past year, from time to time had a drink first thing in the morning to steady your nerves or to get rid of a hangover (eye opener?) Yes/No 5 Have many days per week, do you drink alcohol? 0 days 6 1 day 2 days 3 days 4 days 5 days 6 days Do you drink alcohol on weekdays outside mealtimes? Yes/No Fig. 1. Questionnaires for the Lie/Bet screen and the CAGE-C test used in the Inuit Health in Transition Greenland Survey 20062010. and 1.5% of women all three addictive behaviours were present. Addictive behaviours in households with children In total, the prevalence of one or more addictive behaviours in households with children was 44%. The prevalence of only one addictive behaviour in households with children was similar to households without children (32% vs. 28%), while the prevalence of two or more addictive behaviours was slightly higher in households without children compared to those with children (19% vs. 12%) (p 0.001, results not tabulated). The odds ratio for finding one or more addictive behaviours in a household was slightly lower in households with children compared to households without children (OR 0.76, CI 95%: 0.600.97; adjusted for age group and gender). Discussion Harmful alcohol use and frequent use of marijuana were both associated with lifetime problem gambling and the prevalence of these addictive behaviours was significantly higher among lifetime problem gamblers compared to non-problem gamblers. Among problem gamblers the harmful use of alcohol increased with age while the opposite pattern characterised the non-problem gamblers. For lifetime problem gamblers, the gambling problems were more often than not combined with harmful alcohol use, a frequent use of marijuana or both especially among men. More than half of the men and one third of the women displayed one or more addictive 6 (page number not for citation purpose) behaviours. This was also the case in almost half of the households with children. Our findings regarding co-morbid behaviour are in agreement with international findings from other population-based studies. Lorains et al. (8) found a weighted mean estimate of 29.8% for alcohol use disorder among combined groups of problem and pathological gamblers across 3 population-based studies, although none of these were based on indigenous populations. Two of these studies used the original CAGE questionnaire and found a total prevalence for alcohol use disorder among problem gamblers of 14% in 2005 (24,25). Considering that the original version of CAGE measures harmful alcohol use in a lifetime perspective, while CAGE-C applies for the past year, the prevalence of harmful use of alcohol among lifetime problem gamblers in Greenland seems high especially for men. The combination of alcohol and marijuana in a crossaddictive behaviour is well-known among public health professionals in Greenland, but gambling problems have not systematically been included in strategies for prevention in this field. Our study shows, that the co-occurrence of harmful alcohol use and frequent use of marijuana with lifetime problem gambling is similar to the cooccurrence of harmful alcohol use and frequent use of marijuana. Problem gambling was measured in a lifetime perspective. This means that gambling problems may not be an issue any more, but despite this, there is a prevalent overlap with alcohol problems and frequent use of marijuana in the past year. Based on these observations, Citation: Int J Circumpolar Health 2013, 72: 19551 - http://dx.doi.org/10.3402/ijch.v72i0.19551 Cross-addictive behaviour among Greenland Inuit Fig. 2. Prevalence of lifetime problem gambling, frequent use of marijuana in the past year, harmful alcohol use in the past year and the different combinations between the three as well as no addictive behaviour. The total prevalence of each of the three addictive behaviours as well as no addictive behaviour is written in bold figures. The prevalence of one addictive behaviour only, or the combination of two or three addictive behaviours, is written in (). Unadjusted percent, weighted for regional and age differences in the sample. Men (left), N 579, missing 404. Women (right), N605, missing 601. Greenland Inuit 20062010. it seems important to consider gambling problems as a part of other addictive behaviours, even though these problems may not be current. The high prevalence of one or more addictive behaviours in households with children suggests that many families and children in Greenland are affected by alcohol, gambling and marijuana. A report from the national program for early intervention in pregnant families in Greenland, which had 15% of all families with newborns from 20072010 enrolled, showed that all of these families were struggling with problems related to addictive behaviour (26). The negative influence of alcohol was also stated by the participants in the Inuit Health in Transition Greenland Survey, who rated alcohol to be the most important theme together with violence, when asked to rate the importance of the themes included in Greenland’s first public health program ‘‘Inuuneritta 20072012’’. This evaluation was further supported by results from the Survey of Living Conditions, where participants rated unemployment, alcohol and drug abuse, suicide, violence in the family and sexual abuse as serious social and health-related issues within the Greenlandic communities (27). An increase in social pathologies, such as addictive behaviours, is not only a challenge for Greenland, but a key indicator for indigenous people in the Arctic undergoing a similar transition (4). These issues need to be addressed through comprehensive public health strategies and preventive measures taking the complexity and the fundamental challenges related to sociocultural changes in the Greenlandic society into account. Targeting interventions and treatment for pathological gamblers is a challenge because very few actually seek treatment for their disorder. A large US survey suggested that only 712% of the pathological gamblers seek treatment (28), and Kessler et al. (29) found that none of the problem gamblers in their study had ever received treatment for gambling problems, while half of them were treated for other mental disorders. This corresponds well with the experience from Greenland, where very few have been treated for pathological gambling. In consequence, there seems to be an important task for health professionals and social workers of screening for gambling problems when working with alcohol and substance use disorders. Mental health disorders, such as bipolar disorder, major depression and antisocial personality disorders, have been found to be highly associated with problem gambling (8). However, mental health disorders could not be diagnosed on the basis of the health questionnaire in the Greenland Survey and, therefore, these were not included in the analyses, although they are likely to contribute to the prevalence of addictive behaviours. Given a seemingly high prevalence of mental disorders among Greenland Inuit (30,31), this association is important to consider when public health interventions and treatment are planned in practice. A study based on patients in the Greenlandic health care system Citation: Int J Circumpolar Health 2013, 72: 19551 - http://dx.doi.org/10.3402/ijch.v72i0.19551 7 (page number not for citation purpose) Christina Viskum Lytken Larsen et al. found a prevalence of at least one ICD-10 diagnose among 49% of the patients, with anxiety, somatisation disorder, dysthymia and depression as the most prevalent diagnoses. However these results were based on a small population and cannot be generalised to the broad population. More knowledge about the prevalence and incidence of specific mental disorders among Greenland Inuit is needed and should take the possible link between mental disorders and problem gambling into consideration. Future research should look into the aetiology of pathological gambling in relation to alcohol and substance use disorders, mental health disorders and their interrelatedness. Few studies have tried to establish what comes first based on retrospective questions asking participants to remember their age of onset for different addictive behaviours (29). Prospective studies are needed in order to ensure a better understanding of what comes first and how the prevention and treatment of one disorder might help to prevent other addictive behaviours. Furthermore, research should investigate the causes behind the increase in social pathologies such as addictive behaviours, which have been found to be a key feature in indigenous populations undergoing a similar transition as Greenland Inuit (4). It is considered a strength of the study that different types of addictive behaviours are measured in the same survey. This has provided us with the opportunity to investigate cross-addictive behaviour among lifetime problem gamblers and the prevalence of different combinations of addictive behaviours. The number of problem gamblers in our sample is relatively large, which has made it possible to study the cross-addictive behaviours according to socio-demographic characteristics. It is an important weakness of the study that the response to key variables followed a social gradient. When working with addictive behaviours and socially exposed groups, the missing data is expected to lead to an underestimated prevalence, because these groups are hard to reach through surveys. However, it should be noted that the prevalence found when combining the three different variables for addictive behaviours in this study is slightly higher, compared to the national prevalence estimates, when calculated separately. This is caused by the combination of missing data across the 3 measures, when they are combined in one variable, which reduces the ‘‘N’’. Furthermore, it is possible that gambling and alcohol problems are under-reported in the study, due to the general stigma attached to addictive behaviours. Based on the existing data, we were not able to further asses a possible under-reporting regarding these subjects, but the number of missing data on the lie/bet screen was larger than the number of missing data on questions regarding different types of gambling (not included in this study). This suggests that people are more likely to 8 (page number not for citation purpose) answer questions about gambling activities, rather than gambling problems. Whether this has to do with participants not wanting to answer questions about gambling problems they might have, or with the fact that it is tempting to skip a couple of questions in a long questionnaire if they seem irrelevant to you personally, should be investigated through future qualitative methodological studies. 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DSM-IV pathological gambling in the National Comorbidity Survey Replication. Psychol Med. 2008;38:135160. 30. Lynge I, Munk-Jørgensen P, Lynge Pedersen A, Mulvad G, Bjerregaard P. Common mental health disorders among patients in primary health care in Greenland. Int J Circumpolar Health. 2004;63(Suppl 2):37783. 31. Lynge I, Munk-Jørgensen P, Lynge Pedersen A, Mulvad G, Bjerregaard P. Mental health among patients in the Greenlandic health system [report in Danish]. Copenhagen: National Institute of Public Health; 2003. Report No.: SIFs Writings on Greenland no. 15. *Christina Viskum Lytken Larsen National Institute of Public Health University of Southern Denmark Oester Farimagsgade 5A, 2 1353 Copenhagen K, Denmark Tel: 45 65507070 Fax: 45 39208010 Email: [email protected] Citation: Int J Circumpolar Health 2013, 72: 19551 - http://dx.doi.org/10.3402/ijch.v72i0.19551 9 (page number not for citation purpose) PAPER III Larsen CVL, Curtis T, Bjerregaard P. Health status and health behavior associated with frequent gambling and problem gambling in a large indigenous population – A cross-sectional study based on The Inuit Health in Transition Greenland Survey 2006-2010. Article in review November 2013 Health status and health behavior associated with frequent gambling and problem gambling in a large indigenous population – A cross-sectional study based on The Inuit Health in Transition Greenland Survey 20062010. AUTHORS, AFFILIATION AND ADRESSES: Authors Christina V L Larsen1, Tine Curtis2 and Peter Bjerregaard1 Institutions 1 National Institute of Public Health, University of Southern Denmark, Denmark 2 Local Government Denmark, Denmark E-mails: Christina V L Larsen: [email protected] Peter Bjerregaard: [email protected] Tine Curtis: [email protected] Correspondence: Christina Viskum Lytken Larsen PhD student, MA in Sociology National Institute of Public Health University of Southern Denmark Oester Farimagsgade 5A, 2. E-mail: [email protected]/ Fax: +45 39208010 1353 Copenhagen K, Denmark Tel: +45 65507070 RUNNING HEAD: Gambling and health among Greenland Inuit DECLARATION OF INTEREST: None WORD COUNT: 2,997 ABSTRACT Background Despite a movement towards a public health paradigm for gambling, few studies have investigated pathological gambling in a more general health perspective, and to an even lesser extent gambling behavior has been included in the analytical framework. Indigenous populations undergoing rapid social transition have been found to be vulnerable to gambling problems, but knowledge in this field is needed to develop an evidence based public health approach to gambling activities and pathological gambling. The objective of the study was to investigate health status and health behavior among frequent gamblers and lifetime problem gamblers among Greenland Inuit. Methods A representative cross-sectional study was conducted among Greenland Inuit (18+) (n=2189) in 9 towns and 13 villages in Greenland from 2005-2010. Frequent gambling, lifetime problem gambling, health status and health behavior were measured through clinical examinations, an interview based questionnaire and a self-administered questionnaire. Results Frequent gambling and lifetime problem gambling was associated with a poorer health status and unhealthy behavior. Frequent gamblers and problem gamblers experienced a higher prevalence of mental symptoms, long-standing illness and a poorer self-rated health. Daily smoking, a harmful use of alcohol, a frequent use of marijuana, an unhealthy diet and use of health services was also more prevalent compared to those who gambled less than once a month and non-problem gamblers. Conclusion Variation according to gambling activity and different measures of problem gambling suggests a complex process related to living conditions and socioeconomic differences among Greenland Inuit. Future studies should focus on the social determinants of health and gambling problems among indigenous populations undergoing rapid social transition. INTRODUCTION Pathological gambling has traditionally been an issue of the psychiatric discipline and analyses of comorbidity have focused on mental disorders and addictive behavior. During the last two decades increased attention in public health has been paid to the importance of including gambling behavior and pathological gambling in a public health frame work (1-3). Despite a movement towards a public health paradigm for gambling, few studies have investigated pathological gambling in a more general health perspective and as a result little is known about associations with health status and health behavior (4). To an even lesser extent gambling behavior has been included in the analytical framework, although it is likely that engaging in different types of gambling activities on a frequent basis may be associated with health given specific patterns and ways of life that characterize different gambling activities. Indigenous populations experience a higher prevalence of gambling problems compared to their nonindigenous counterparts (5-7). The rapid transition among indigenous populations in the Circumpolar North has also been accompanied by an epidemiological transition from infectious diseases to chronic diseases (8). The changing lifestyles and health conditions as well as an increase in social pathologies among indigenous populations in the Circumpolar North call for more knowledge on possible associations between on one hand frequent gambling and gambling problems, and on the other, health in general among these populations. Gambling was therefore included as a topic in the Inuit Health in Transition Survey covering both Inuit in Nunavik (Canada) and Greenland (9;10). This study is based on results from the Inuit Health in Transition Greenland Survey. Given a high prevalence of lifetime problem gambling among Greenland Inuit (11), the survey represents a unique opportunity to analyze gambling behavior in a broader health perspective relevant for public health planning with focus on indigenous populations. The objective of the study was to investigate the general health status and health behavior according to frequent gambling and lifetime problem gambling in a representative sample of Greenland Inuit. METHODS AND MATERIAL Study design, setting and participants Data were derived from the cross-sectional Inuit Health in Transition Greenland Survey 2005-2010 - a population based general health study among a representative sample of adults (18+). A full methodological report of the study is published elsewhere (9). Data was collected as clinical examinations as well as through a structured interview conducted by the interviewers in either Greenlandic of Danish based on the choice of the participant, and finally through a self-administered questionnaire that was filled out by the participant at the location after the clinical examinations and interview. Questions about gambling were included in the self-administered questionnaire from 2006 and onwards. The sample for 2006-2010 included 3,893 Greenland Inuit. A total of 2,451 persons participated in the general survey (63%) and 2,189 persons filled out the self-administered questionnaire (56%). The analyses were based on these 2,189 participants. In total 2,012 of the 2,189 participants (92%) answered at least one question about gambling. Greenland has a total of 80 communities all located along the coast divided into towns and villages. A town is defined historically as the largest community in each of 17 districts. In 2010, the population of the towns varied between 469 to 5,460 and 15,469 in the capital Nuuk while that of villages varied from less than 10 to around 550. In the towns are located district school(s), health center or hospital, church, district administration and main shops. These institutions are absent or present to a much smaller extent in villages. Despite its large geographical size, the total population of Greenland is only about 57,000 of whom 90% are ethnic Greenlanders (Inuit). Genetically, Greenlanders are Inuit (Eskimos) with a mixture of European, mainly Scandinavian genes. Greenlanders are both genetically and culturally closely related to the Inuit/Iñupiat in Canada and Alaska and, somewhat more distantly, to the Yupiit of Alaska and Siberia (8). Gambling behavior and problem gambling Frequent gambling was measured through the self-administered questionnaire. Respondents were asked how often they gambled during past year regarding the lottery, bingo, cards/dice and slot machines and answers were dichotomized into gambling once a month or more vs. less than once a month for each type of activity. Problem gambling was measured using the lie/bet screen (12), which has been validated in both treatment (13) and community samples (14). It is a two questions version of the 10 DSM-IV criteria for pathological gambling (15). The lie/bet screen has been found valid to identify lifetime problem gamblers in a community sample, defined as those who responded positively to five or more of the 10 DSM-IV criteria combined with those who only responded positively to three-four of these criteria (14). The short screen does not qualify to distinguish between pathological and problem gambling. Positive answers to one or both questions for past year and previously were combined into a measure of lifetime problem gambling. Two additional questions were included to measures problem gambling. Respondents were asked a) if they felt they had spent too much time or money on gambling during past year or previously and b) whether they themselves had ever considered they had a gambling problem or had been told so by others during past year or previously. Positive answers for past year and previously were combined into a measure of lifetime problem gambling for each of these variables. Health status Self-rated health was measured in the interview questionnaire by asking respondents to rate their own health within five categories: Excellent, good, fair, poor, very poor. Answers were dichotomized into excellent/good vs. fair/poor/very poor. Mental symptoms were measured in the interview questionnaire, by asking respondents whether they had been bothered a little, a lot or not at all by (a) anxiety, nervousness, agitation, or fear (hereafter anxiety); or (b) feeling depressed or unhappy (hereafter depression), in the two weeks preceding the interview. Dichotomous variables were created to identify people reporting feeling anxious vs. those who did not, and people reporting feeling depressed vs. those who did not. Long-standing illness was assessed through interview by asking: Do you suffer from any longstanding illness, after-effect of an injury, handicap or other long-standing disorder? Yes/no. If a person answered yes, they were asked to specify their illness. Only the dichotomized variable based on yes/no was used in this study. Finally height and weight were measured with the participants stripped to their underwear and socks (9). Weight was measured on a standard electronic clinical scale. Body Mass Index (BMI) was calculated based on these measurements (kg/m2) and dichotomized according to a BMI above or below 30. Participants with a BMI of 30+ were classified as obese (16). Health behavior Information about daily smoking was obtained from the interview questionnaire. Harmful alcohol use was measured by the modified CAGE-test, CAGE-C, which is a simple screening tool suited for identifying alcohol problems in populations with a high prevalence of at-risk drinkers. The six-item questionnaire CAGE-C was suggested by Zierau et al. in 2005 (17) and validated against a diagnostic interview based on ICD-10 (18) and DSM-III R (19) criteria. The questionnaire has been used to assess harmful alcohol intake among Greenland Inuit in an earlier study (20). Frequent use of marijuana during past year was measured through the self-administered questionnaire. Those who had tried to smoke marijuana and additionally answered they had smoked at least 1-3 times a month during past year were categorized as past year frequent users of marijuana vs. non-frequent users/non users. Sedentary time was measured through the interview questionnaire based on two questions regarding time spent on sitting during weekdays and weekend respectively based on the past seven days from the International Physical Activity Questionnaire (IPAQ) adapted for living conditions in Greenland (17;18). The variable was dichotomized using the median in order to compare the 50% with the most sedentary time to the 50% with the least sedentary time (>3 hours vs. <3 hours daily). Information on unhealthy diet was obtained by an interviewer-administered Food Frequency Questionnaire (FFQ) with portion sizes. The FFQ was developed from information obtained through a 24-hour dietary recall. Questions were asked about 67 food items, including 23 local and 44 imported items (9). An unhealthy diet was defined as 25 E% or more from soda pop, fast food, snacks, sweets and sugar added to coffee or tea (19). Information regarding use of health services was obtained from the interview questionnaire. Consultations with a doctor, nurse or healthcare assistant at the local health center or hospital during the three months preceding the interview was registered as having made use of health services during the past three months. Sociodemographic characteristics Age was divided into four groups; 18-24, 25-34, 35-59 and 60+ years. Place of residence was divided into villages, towns and the capital. Formal education was included as a measure of socioeconomic position and determined from questions in the interviewer based questionnaire about highest school education attained and further vocational or academic education and recoded into primary school/high school only, short vocational education (less than 3 years), and longer vocational/academic education. Statistical analyses Statistical analyses were performed in IBM SPSS Statistics 19. Due to the sampling procedure, oversampling took place in certain strata while the participation rate was not similar according to age and gender. Accordingly, data were weighted for sampling strata by the weight procedure of SPSS in order to obtain representative prevalence estimates. All variables regarding health behavior and health status were dichotomous and analyzed by logistic regression. Regressions were performed separately for men and women for one health outcome at a time and adjusted for age group (treated as a categorical variable), formal education and place of residence. Ethical review The study was ethically approved by the Commission for Scientific Research in Greenland. Participants gave their written consent after being informed about the study orally and in writing. [INSERT TABLE 1] RESULTS Key variables are shown in Table 1. Frequent gambling on the lottery, bingo as well as cards/dice was associated with several measures of both health status and health behavior, but most associations were only significant for either men or women (Table 2). In general frequent gambling was associated with a poorer health status or an unhealthier behavior compared to those who never gambled or gambled less than once a month, but significant differences characterized different types of gambling activities. Daily smoking was almost two-three times higher among frequent players of bingo, cards/dice and slot machines – especially among women – while the overall prevalence of daily smoking among those who gambled frequently on the lottery was a little lower compared to those who did not. A harmful use of alcohol was also less prevalent among male lottery players and among bingo players. Only poor self-rated health and use of health services were not significantly associated with any types of frequent gambling. [INSERT TABLE 2] All measures of health status and health behavior except sedentary time were significantly associated with lifetime problem gambling, but some variation applied according to gender and measure of problem gambling (Table 3). Lifetime problem gamblers had a poorer health and an unhealthier behavior compared to non-problem gamblers with obesity as the exception. Women who reported having spent too much time or money on gambling were less obese than non-problem gamblers. Symptoms of anxiety and depression during the past two weeks, daily smoking and harmful use of alcohol were significantly more prevalent among lifetime problem gamblers no matter how problem gambling was measured. Respondents’ perception of having spent too much time or money on gambling was associated with most of the included outcomes. [INSERT TABLE 3] DISCUSSION Frequent gambling and lifetime problem gambling were associated with a poorer health and unhealthy behavior. Associations varied according to type of gambling and how problem gambling was measured with significant gender differences. More frequent gamblers and lifetime problem gamblers experienced mental symptoms, long-standing illness, a poorer self-rated health, smoked daily, had a harmful use of alcohol and smoked marijuana frequently, enjoyed an unhealthy diet and had made more use of health services compared to those who gambled less frequently or never gambled as well as non-problem gamblers. Exceptions were depression, daily smoking, harmful alcohol use and sedentary time during the day among those who gambled frequently on the lotteries and bingo, because fewer were depressed, sedentary, smoked daily and were obese compared to non-frequent gamblers. The associations found between problem gambling and mental symptoms, smoking, harmful alcohol use and frequent use of marijuana are consistent with international findings from population based surveys (20). The empirical literature regarding problem gambling and health beyond mental disorders, smoking, substance and alcohol use is limited, but the existing studies found lifetime pathological gambling to be associated with several medical disorders, poor lifestyle choices and worse quality of life (21;22). Our results thus support these findings, although they are not directly comparable because they are based on different populations and different measures of gambling problems. The positive health outcomes associated with frequent gambling could indicate a social gradient in preference for type of gambling and problem gambling. The lotteries are played more among the highest educated in Greenland (unpublished results), which would explain why the unadjusted analyses show a lower prevalence of symptoms of depression and daily smoking among those who gamble frequently on the lottery. Lifetime problem gamblers were found to be less obese, which could be explained by a higher prevalence of problem gamblers in less privileged groups. Obesity among Greenland Inuit follows a social gradient according to wealth, meaning the wealthier the more obese (unpublished results). The lower OR for obesity among lifetime problem gamblers was significant for women even after adjusting for formal education, suggesting the association is even more complex than the inequalities in health often found in relation to different levels of education. Due to the nature of a cross-sectional survey, our data does not provide any information regarding causality between health and gambling. The Pathways Model of problem gambling suggested by Blaszczynski and Nower (23) argues that problem gamblers are a heterogeneous group and proposes three different pathways. The first pathway covers problem gamblers with no severe psychological problems prior to their extensive gambling, but where alcohol abuse, depression and anxiety might appear as a result of their gambling; the second pathway covers a group where emotional vulnerability due to for example childhood disturbance is present prior to the gambling problems. This group uses gambling to modify affective states or meet specific needs. The third pathway is constituted by highly disturbed individuals with substantial psychological features such as impulsivity and antisocial personality disorder. Given a high prevalence of traumatic events during childhood and the documented association with mental health among Greenland Inuit (24-26) a pathway to problem gambling through emotional vulnerability is a relevant perspective. However none of the pathways are based on empirical findings among indigenous populations where sociocultural and societal changes are important determinants of both physical and mental health (27). The associations between gambling and a poorer health as well as unhealthy behavior are likely to be a result of an even more complex process related to living conditions and socioeconomic differences among Greenland Inuit. This perspective follows the theoretical approach proposed by Marmot and Wilkinson regarding social determinants of health (28), which states that health follows a social gradient meaning the higher the social position, the better the health. The focus of epidemiological research should be the causes of causes such as different behavioral determinants of biological markers and the living conditions and circumstances that influence peoples’ access to a healthy lifestyle. These causes are defined as social determinants of health. Following this line of thought future research should focus on the social determinants of poor health and unhealthy life among Greenland Inuit and how gambling behavior and problem gambling are linked to these determinants. Because of its brief character, the lie/bet screen is likely to cover very mild gambling problems along with more severe ones compared to more comprehensive screens (29;30). However, it is an important finding that associations with health are significant despite this methodological issue. It is interesting that associations between problem gambling and health are significant even when using one-item questions of participants’ own perception to assess lifetime problem gambling. Although these one-item measures based on peoples own perception of their gambling problems cannot be used to diagnose pathological gamblers in a clinical context, self-perceived health measures are an important source of information from a public health point of view. It is well known, that self-rated health is a significant predictor for mortality (31;32). The negative health outcomes associated with participants feeling they spent too much time or money on gambling or who rate themselves as problem gamblers could serve as an important source of information for health professionals and social workers regarding when to intervene. A particular strength of the study are the various topics included in the general health survey and the representative sample of a large indigenous population, which provides us with new insight regarding health and gambling in a vulnerable population. A weakness of the study is the cross-sectional design which makes it impossible to establish the causality of the associations. Also, there is a risk of selection bias due to sociodemographic differences in the missing data. Another weakness is the fact that the lie/bet screen has only been used in few other studies. This makes it difficult to compare our results with other studies. More epidemiological as well as qualitative research is needed to understand the relationship between health and gambling among Greenland Inuit and other indigenous populations. Prospective and register based studies are needed to investigate causality in the relationship between health and gambling and to identify the possible underlying social determinants. CONCLUSION Frequent gambling and lifetime problem gambling was associated with a poorer health and unhealthy behavior. Variation according to gambling activity and different measures of problem gambling suggests a complex phenomenon related to living conditions and socioeconomic differences among Greenland Inuit. Future studies should focus on the social determinants of health and gambling problems among vulnerable populations. REFERENCES (1) Korn D, Gibbins R, Azmier J. Framing public policy towards a public health paradigm for gambling. 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Common mental health disorders among patients in primary health care in Greenland. International Journal of Circumpolar Health 2004;63(Supplements 2):377-83. (25) Bjerregaard P, Curtis T. Cultural change and mental health in Greenland. The association of childhood conditions, language and urbanization with mental health and suicidal thoughts among the Inuit of Greenland. Social Science and Medicine 2002;(54):-33. (26) Curtis T, Larsen FB, Helweg-Larsen K, Bjerregaard P. Violence, sexual abuse and health in Greenland. International Journal of Circumpolar Health 2002;61(2):110-22. (27) Curtis T, Kvernmo S, Bjerregaard P. Changing living conditions, life style and health. Journal of Circumpolar Health 2005;64(5):442-50. (28) Marmot M, Wilkinson RG. Social Determinants of Health. Second edition ed. New York: Oxford University Press; 2011. (29) Lesieur HR, Blume SB. Revising the South Oaks Gambling Screen in different settings. Journal of Gambling Studies 1993;9(3):213-23. (30) Gerstein DR, Arwood RA, Hoffmann J, Larison C, Engelman L, Murphy S. Gambling impact and behavior study. Report to the National Gambling Impact Study Commission. Chicago: National Opinion Research Center at the University of Chicago.; 1999. (31) DeSalvo KB, Bloser N, Reynolds K, He J, Muntner P. Mortality prediction with a single general selfrated health question. A meta-analysis. Journal of Gen Intern Medicine 2006;21:267-75. (32) Idler EL, Benyamini Y. Self-rated health and mortality: a review of twenty-seven community studies. Journal of Health and Social Behavior 1997;38:21-37. Table 1. Overview of key variables included in the study. Frequency, valid percent and missing data. Greenland Inuit 2006-2010 (N=2189). Frequency (Pct.) Sociodemographic characteristica N Missing data 2189 0 Gender Men Women Frequency (Pct.) Health status Anxiety 983 (44.9) 1206 (55.1) 2189 0 Yes 730 (33.4) No 1456 (66.6) 18-24 278 (12.7) Depression 25-34 Yes 605 (27.7) 35-59 385 (17.6) 1273 (58.2) No 1576 (72.3) 60+ 253 (11.6) Place of residence Long-standing illness Yes 777 (35.8) No 1395 (63.6) Town 419 (19.1) 1110 (50.7) Village 660 (30.2) Excellent/good Formal education Primary school/high school only 2189 1312 (60.7) 0 Self-rated health 2161 28 Fair/poor/very poor 620 (28.7) BMI < 30 1681 (77.5) Longer vocational/academic education 229 (10.6) BMI > 30 489 (22.5) 1751 No Gambled on slot mashines at least once a month 438 447 (25.5) 1304 (74.5) Gambled on bingo at least once a month Yes 2181 8 2172 17 2181 8 2170 19 2189 0 1599 590 1833 356 Health behavior Gambled on the lotteries at least once a month No 3 794 (36.4) Obesity Gambling behavior during past year 2186 1387 (63.6) Short vocational education (less than 3 years) Yes Missing data Mental symptoms during past two weeks Age groups Nuuk N 1888 301 459 (24.3) 1429 (75.7) 1679 510 Daily smoker 793 (36.2) Yes 1369 (63.8) No 793 (36.2) Harmful alcohol use past year (CAGE-C) Yes 521 (32.6) No 1078 (67.4) Frequent use of marijuana past year (smoked at least once a month) Yes No Gambled on cards and dice at least once a month Yes No 68 (4.1) 1611 (95.9) 1731 458 210 (12.1) 1521 (87.9) Lie/bet screen Non-problem gambler/ never gamble 1542 No/never gamble No/ never gamble No 1583 (86.4) Sedentary time during past 7 days 3 hours or less daily 1082 (50.8) More than 3 hours daily 1047 (49.2) 465 254(14.7) 1470 (85.3) 1500 113 (7.5) 1387 (92.4) Yes 617 No 1572 Use of health services during past 3 months 1724 Selfrated problem gambling Yes, past year or previously (lifetime) 647 196 (12.7) 1346 (87.3) Spent too much time or money on gambling Yes, past year or previously (lifetime) 250 (13.6) Unhealthy diet Problem gambling Lifetime problem gambler Yes Yes 841 (43.9) No 1073 (56.1) 2129 60 2189 0 1914 275 689 Sociodemographic variation applied to the response rates for questions regarding gambling behavior, problem gambling and the measures of health behavior. For the questions regarding gambling behavior, harmful alcohol use, frequent use of marijuana and having spent too much time or money on gambling, the odds ratio (OR) for answering was higher among men compared to women and among inhabitants in the capital compared to inhabitants from towns and villages. The OR decreased with age and increased with level of education. Following the same pattern, response to selfrated problem gambling was associated with gender, age group and formal education but not place of residence and response to the lie/bet screen was only associated with gender and age group. Response to use of health services was associated with place of residence and formal education, but with a decrease in ORs for having answered with increase in level of education. Table 2. Prevalence and odds ratio (OR) for different measures of health status and health behavior among frequent gamblers (at least once a month during past year) on the lotteries, bingo, cards/dice and slot maschines. Past year problem gamblers (lie/bet screen) were excluded in the analyses. The general prevalence was weighted for regional, gender and age differences in the sample. Binary logistic regressions were performmed for men and women seperately and both unadjusted and adjusted for age group, formal education and place of residence. Odds ratios are shown with 95% confidence intervals. Greenland Inuit 2006-2010. HEALTH STATUS Monthly gambling on…. The lotteries (N=1751) Yes (men=263; women=184) No (men=564; women=740) p-value OR, Men [C.I. 95%] Unadjusted Adjusted OR, Women [C.I. 95%] Unadjusted Adjusted Bingo (N=1888) Yes (men=153; women=306) No (men=695; women=734) p-value OR, Men [C.I. 95%] Unadjusted Adjusted OR, Women [C.I. 95%] Unadjusted Adjusted Cards/dice (N=1731) HEALTH BEHAVIOR Anxiety Depression Longstanding illness 27.6 30.3 0.212 20.0 24.4 0.045 33.2 32.9 0.902 1.04 [0.73-1.48] 1.10 [0.75-1.60] 0.95 [0.65-1.39] 1.01 [0.67-1.52] Harmful Sedentary time alcohol use during past 7 (past year) Frequent use days (> 3 hours CAGE-C of marijuana daily) Poor selfrated health Obesity (BMI >30) Daily smoker 33.3 34.2 0.711 24.7 22.8 0.387 55.9 60.9 0.048 31.0 31.6 0.818 15.4 17.4 0.308 0.86 1.01 [0.63-1.19] [0.73-1.39] 0.93 1.05 [0.65-1.32] [0.74-1.48] 1.50 [1.04-2.16] * 1.19 [0.81-1.76] 1.07 [0.79-1.46] 1.19 [0.85-1.66] 0.67 [0.47-0.94] * 0.68 [0.47-0.99] * 1.41 [0.95-2.10] † 1.13 [0.74-1.73] 0.83 1.33 0.90 [0.58-1.20] [0.94-1.86] [0.63-1.27] 1.03 1.37 1.06 [0.70-1.51] [0.95-1.98] † [0.73-1.53] 1.03 [0.71-1.50] 1.06 [0.71-1.58] 0.82 [0.59-1.15] 0.97 [0.68-1.39] 0.89 [0.59-1.39] 0.94 [0.61-1.44] 35.1 34.2 0.727 23.5 23.2 0.884 70.3 56.7 >0.0001 21.8 33.7 >0.0001 15.7 16.1 0.864 1.22 1.81 [0.81-1.83] [1.20-2.72] * 1.26 1.90 [0.82-1.93] [1.24-2.92] * 0.97 1.24 [0.67-1.42] [0.85-1.80] 0.77 1.12 [0.52-1.53] [0.75-1.64] 1.04 [0.66-1.64] 0.94 [0.58-1.52] 1.57 [1.07-2.31] * 1.69 [1.13-2.55] * 0.82 [0.54-1.24] 0.73 [0.47-1.12] 1.04 [0.79-1.37] 1.00 [0.74-1.34] 1.21 0.98 [0.91-1.61] [0.75-1.32] 0.99 0.81 [0.73-1.34] [0.60-1.10] 0.89 2.27 [0.65-1.22] [1.67-3.10] *** 0.71 2.21 [0.51-0.99] * [1.59-3.08] *** 0.94 [0.66-1.34] 0.91 [0.62-1.33] 1.33 [0.95-1.86] † 1.62 [1.13-2.30] ** 32.6 29.4 0.217 29.9.6 22.4 0.002 1.08 [0.81-1.45] 0.96 [0.71-1.31] 30.8 34.0 0.227 Unhealthy diet Use of health services during past 3 months 58.8 54.6 0.107 27.2 29.3 0.376 41.0 40.6 0.898 1.12 [0.83-1.52] 0.88 [0.64-1.23] 1.06 [0.76-1.46] 1.16 [0.81-1.66] 1.14 [0.82-1.60] 0.97 [0.67-1.40] 0.73 1.86 [0.40-1.32] [1.32-2.63] *** 0.59 1.53 [0.31-1.11] [1.05-2.21] * 0.90 [0.62-1.31] 0.98 [0.65-1.47] 1.22 [0.86-1.73] 1.17 [0.80-1.69] 47.7 56.4 0.002 26.3 29.0 0.275 44.2 40.1 0.166 1.11 [0.68-1.83] 1.18 [0.70-2.01] 0.64 [0.45-0.92] * 0.72 [0.49-1.05] † 1.24 [0.85-1.81] 1.59 [1.06-2.41] * 1.26 [0.85-1.87] 1.12 [0.74-1.69] 1.02 [0.62-1.67] 1.29 [0.75-2.23] 0.79 [0.60-1.05] 1.06 [0.79-1.44] 1.11 [0.82-1.50] 0.89 [0.67-1.20] 1.31 0.95 [0.94-1.82] [0.69-1.30] Yes (men=106; women=104) No (men=701; women=820) p-value OR, Men [C.I. 95%] Unadjusted Adjusted OR, Women [C.I. 95%] Unadjusted Adjusted Slot maschines (N=1679) Yes (men=44; women=24) No (men=742; women=869) p-value OR, Men [C.I. 95%] Unadjusted Adjusted OR, Women [C.I. 95%] Unadjusted Adjusted 38.8 29.4 35.4 22.3 27.9 32.6 33.8 34.0 17.9 23.2 79.7 58.0 36.1 30.9 25.4 15.9 53.5 55.8 33.3 27.4 36.6 42.2 0.018 <0.0001 0.246 0.964 0.146 <0.0001 0.239 0.005 0.699 0.122 0.229 1.48 1.62 [0.92-2.36] [0.96-2.65] † 1.39 1.61 [0.86-2.27] [0.97-2.66] † 0.87 0.98 [0.55-1.38] [0.62-1.56] 0.93 0.99 [0.57-1.52] [0.62-1.59] 1.13 [0.66-1.94] 1.36 [0.77-2.39] 1.89 [1.17-3.05] ** 1.50 [0.91-2.46] 1.42 [0.87-2.33] 1.35 [0.82-2.25] 1.63 [0.94-2.80] † 1.61 [0.91-2.84] 0.60 [0.39-0.94] * 0.67 [0.42-1.06] † 1.46 [0.95-2.24] 1.32 [0.84-2.08] 0.87 [0.53-1.42] 0.99 [0.59-1.65] 1.17 1.70 [0.76-1.80] [1.10-2.63] * 1.00 1.41 [0.64-1.55] [0.90-2.20] 1.10 1.19 [0.71-1.72] [0.77-1.85] 1.06 1.04 [0.67-1.69] [0.66-1.63] 0.71 3.70 [0.43-1.20] [2.06-6.66] *** 0.66 3.23 [0.39-1.13] [1.79-5.86] *** 0.98 [0.57-1.66] 0.84 [0.49-1.46] 1.50 [0.78-2.90] 1.57 [0.77-3.18] 1.30 [0.84-2.00] 1.74 [1.10-2.75] * 1.31 [0.84-2.03] 1.32 [0.84-2.10] 0.84 [0.54-1.31] 0.84 [0.53-1.33] 21.1 30.2 0.102 14.3 23.3 0.079 0.77 [0.33-1.79] 0.77 [0.27-1.90] 0.93 [0.40-2.15] 0.71 [0.27-1.90] 39.4 33.9 0.334 24.3 23.2 0.826 65.7 59.6 0.304 37.9 31.3 0.291 19.7 16.7 0.529 52.4 56.2 0.388 45.7 27.6 0.001 53.2 41.3 0.062 0.96 [0.41-2.23] 1.03 [0.44-2.43] 0.90 1.08 [0.43-1.87] [0.53-2.20] 0.98 1.41 [0.45-2.14] [0.63-3.15] 1.43 [0.66-3.13] 1.41 [0.60-2.73] 1.46 [0.71-3.01] 1.37 [0.65-2.87] 1.27 [0.59-2.74] 1.27 [0.57-2.82] 1.87 [0.85-4.12] 1.51 [0.67-3.42] 1.40 [0.70-2.78] 1.26 [0.61-2.58] 1.41 [0.70-2.83] 1.29 [0.62-2.70] 1.50 [0.73-3.10] 1.69 [0.79-3.63] 0.62 [0.20-1.90] 0.77 [0.25-2.41] 1.15 1.65 [0.45-2.94] [0.66-4.09] 0.96 1.67 [0.36-2.53] [0.63-4.44] 1.69 [0.66-4.34] 1.67 [0.63-4.44] 1.65 [0.59-4.62] 2.32 [0.81-6.64] 0.38 [0.09-1.71] 0.38 [0.08-1.73] 1.03 [0.23-4.58] 0.91 [0.20-4.21] 0.88 [0.36-2.20] 0.62 [0.24-1.63] 1.58 [0.61-4.06] 2.19 [0.82-5.83] 0.95 [0.35-2.55] 0.81 [0.30-2.22] *** p < 0.001; ** p < 0.01; * p < 0.05; † < 0.10 28.8 32.9 0.483 Table 3. Prevalence and odds ratio (OR) for different measures of health status and health behavior among lifetime problem gamblers (different measures applied). The general prevalence was weighted for regional, gender and age differences in the sample. Binary logistic regressions were performmed for men and women seperately and both unadjusted and adjusted for age group, formal education and place of residence. Odds ratios are shown with 95% confidence intervals. HEALTH STATUS HEALTH BEHAVIOR Anxiety Depression Longstanding illness 34.0 31.9 0.547 30.7 24.3 0.048 37.3 32.1 0.146 1.36 1.72 [0.88-2.10] [1.11-2.66] * 1.08 [0.71-1.63] 1.44 1.68 [0.92-2.25] [1.08-2.64] * 1.23 [0.79-1.92] 1.64 [1.10-2.46] * 1.64 [1.09-2.48] * Unadjusted 1.61 1.86 [1.01-2.56] * [1.16-2.97] * 1.29 [0.80-2.07] 1.21 [0.76-1.93] 0.82 [0.48-1.41] Adjusted 1.62 1.76 [1.01-2.61] * [1.08-2.86] * 1.32 [0.80-2.16) 1.16 [0.71-1.88] 0.77 [0.44-1.33] 2.33 [1.32-4.10] ** 2.26 [1.26-4.04] ** 36.5 31.9 0.155 40.5 34.0 0.049 15.4 24.3 0.002 66.5 59.1 0.028 0.96 [0.63-1.47] 1.61 [1.08-2.40] * 1.08 [0.70-1.67] 1.62 [1.08-2.43] Lifetime problem gambling Lie/bet screen (N=1542) Problem gamblers (men=116; women=80) Non-problem gamblers/ non-gamblers p-value OR, Men [C.I. 95%] Unadjusted Adjusted OR, Women [C.I. 95%] Too much time and money… (N=1724) Yes (men=117; women=137) No (men=694; women=776) p-value OR, Men [C.I. 95%] 40.9 29.1 >0.0001 Unadjusted 1.96 [1.29-2.97] ** Adjusted 1.97 [1.29-3.02] ** 33.5 22.0 >0.0001 2.02 [1.31-3.12] ** 2.05 [1.32-3.19] ** Poor selfrated health 43.7 34.8 0.013 Obesity (BMI >30) Daily smoker 20.0 23.6 0.260 73.3 59.9 >0.0001 1.09 [0.66-1.79] 1.35 [0.89-2.06] 1.16 [0.69-1.95] 1.29 [0.83-2.01] Harmful alcohol use (past year) Frequent use CAGE-C of marijuana 45.8 29.5 >0.0001 37.6 14.6 >0.0001 2.24 [1.44-3.48] 1.74 *** [1.07-2.83] * 2.25 [1.44-3.54] 1.66 *** [1.00-2.76] * Sedentary time during past 7 days (> 3 hours daily) Unhealthy diet Use of health services during past 3 months 60.5 53.9 0.076 43.7 34.8 0.013 43.8 42.0 0.664 1.06 1.66 [0.71-1.58] [1.10-2.50] * 1.45 [0.93-2.27] † 1.11 1.47 [0.74-1.68] [0.95-2.27] † 1.46 [0.92-2.32] 1.35 [0.84-2.16] 1.46 [0.90-2.37] 1.10 [0.67-1.81] 1.46 [0.89-2.38] 1.53 [0.92-2.53] 1.11 [0.67-1.85] 1.46 [0.82-2.60] 2.75 [1.44-5.25] ** 2.81 [1.42-5.56] ** 39.9 28.9 0.002 24.4 15.9 0.002 51.7 55.7 0.254 38.0 27.5 0.001 51.7 38.9 0.001 0.65 [0.37-1.13] 1.35 1.83 1.77 [0.89-2.06] [1.19-2.83] ** [1.09-2.87] * 0.79 [0.53-1.18] 1.73 [1.15-2.60] ** 0.63 [0.35-1.11] 1.26 1.86 1.60 [0.82-1.94] [1.19-2.89] ** [0.98-2.64] † 0.79 1.62 [0.52-1.18] [1.06-2.47] * 1.72 [1.12-2.65] * 1.76 [1.12-2.74] * 1.58 [0.90-2.77] OR, Women [C.I. 95%] 0.64 [0.41-1.00] 1.52 2.00 * [1.02-2.27] * [1.32-3.03] ** 0.55 [0.35-0.88] 1.38 1.87 * [0.92-2.08] [1.22-2.87] ** Unadjusted 1.24 [0.86-1.79] 1.35 [0.98-1.96] 1.36 [0.93-1.98] 1.08 [0.74-1.57] Adjusted 1.11 [0.761.61] 1.13 [0.76-1.67] 1.24 [0.84-1.83] 1.01 [0.68-1.49] 41.0 31.4 35.6 24.4 48.5 32.2 44.6 35.0 18.8 23.8 69.3 60.4 0.046 0.012 0.001 0.054 0.252 1.07 [0.60-1.92] 1.25 [0.71-2.21] 1.23 [0.66-2.27] Self-rated problem gambling (N=1500) Yes (men=54; women=59) No (men=663; women=724) p-value OR, Men [C.I. 95%] Unadjusted Adjusted OR, Women [C.I. 95%] 1.69 [0.94-3.04] † 1.76 [0.95-3.25] † Unadjusted 1.66 [0.97-2.82] † Adjusted 1.69 [0.98-2.92] † 2.44 [1.37-4.35] ** 2.54 [1.39-4.63] ** 2.45 [1.44-4.19] ** 2.44 [1.40-4.24] ** 2.49 [1.45-4.25] ** 2.21 [1.27-3.84] ** 1.35 [0.76-2.41] 0.96 [0.66-1.39] 1.34 [0.90-1.97] 0.98 [0.66-1.45] 1.49 [0.81-2.76] 1.18 [0.80-1.76] 1.37 [0.91-2.07] 0.99 [0.66-1.48] 38.4 30.7 24.5 17.0 62.6 53.8 34.7 28.5 53.8 41.3 0.077 0.140 0.065 0.088 0.187 0.030 1.09 [0.54-2.16] 1.15 [0.65-2.06] 2.00 [1.08-3.72] * 1.73 [0.89-3.36] 1.27 [0.72-2.24] 1.44 [0.81-2.57] 1.50 [0.81-2.78] 1.24 [0.69-2.24] 1.05 [0.51-2.13] 1.26 [0.68-2.33] 2.13 [1.12-4.06] * 1.47 [0.73-2.96] 1.06 [0.59-1.91] 1.39 [0.75-2.56] 1.58 [0.83-3.01] 1.50 [0.88-2.56] 0.75 2.04 [0.40-1.42] [1.08-3.85] * 1.10 [0.59-2.06] 1.01 [0.39-2.64] 1.49 [0.81-2.75] 1.49 [0.86-2.59] 0.64 1.99 [0.33-1.22] [1.04-3.81] * 1.00 [0.53-1.91] 1.15 [0.43-3.10] 1.35 1.43 [0.79-2.33] [0.82-2.49] 1.70 [0.96-3.00] 1.71 † [0.96-3.05] † 1.51 [0.81-2.81] *** p < 0.001; ** p < 0.01; * p < 0.05; † < 0.10. Analyses of the association between the included measures of lifetime problem gambling showed the measures were significantly associated with each other (p<0.0001, results not tabulated). The OR for having spent too much time and money on gambling, if you were a lifetime problem gambler according to the lie/bet screen, was 9 (C.I. 95%: 6.3-12.7) and the OR for self-rated problem gambling was 17 (C.I. 95%: 10.7-25.9). If you had spent too much time and money on gambling, the OR for self-rated problem gambling was 21 (C.I. 95%: 13.0-33.2). However, a kappa<0.4 for all two-way combinations, indicated a poor agreement between the included measures of lifetime problem gambling. ISSN: 1601-7765 ISBN: 978-87-7899-263-5 ISBN: 978-87-7899-264-2
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