FINAL EXAMINATION AUGUST 2014 SEMESTER COURSE COURSE CODE DURATION FACULTY PROGRAMME LECTURER : : : : : HISTOLOGY MLD 2122 2 HOURS 30 MINUTES BIOMEDICAL AND HEALTH SCIENCES DIPLOMA IN MEDICAL LABORATORY TECHNOLOGY : MDM ANUSHIA A/P SWAMINATHAN INSTRUCTIONS TO CANDIDATES This paper consists of three (3) sections: Section A – 30 questions (objective questions) Section B – 3 questions (short answer questions) Section C – 3 questions (essay questions) Answer all questions in Section A and B and two questions in Section C. All answers of: Section A must be written in OMR objective paper provided. Section B and Section C must be written in the answer booklet provided. The answer for each question must start on a new page. Candidates are NOT ALLOWED to bring any unauthorized items into the exam hall except with the permission of your invigilator. Do Not Open the Question Paper Until Instructed This Question Paper Consists of Ten (10) Printed Pages CONFIDENTIAL FBHS/MLD2122/AUG2014 SECTION A: OBJECTIVE QUESTIONS (30 MARKS) CHOOSE ONE BEST STATEMENT TO ANSWER THE QUESTIONS 1. To enter or leave a cell, substances must pass through (A) (B) (C) (D) 2. A peripheral membrane protein has which of the following properties? (A) (B) (C) (D) 3. be smaller have a smaller nucleus lack a plasma membrane have a greater variety of organelles The tissues of the body are assigned to four principle types. Which of these covers the body surfaces, lines cavities and ducts, and forms glands? (A) (B) (C) (D) 5. tightly lodged protrudes from only one membrane surface protrudes from both sides of the membrane loosely associated with the inner or outer membrane surface Bacterial cell are prokaryotic; in comparison to a typical eukaryotic cell they would (A) (B) (C) (D) 4. the nucleus a ribosome the Golgi apparatus the plasma membrane muscle tissue nervous tissue epithelial tissue connective tissue The epithelium found lining small tubules and glands that have secretory or absorptive functions is (A) (B) (C) (D) cuboidal columnar squamous ciliated columnar CONFIDENTIAL/2 FBHS/MLD2122/AUG2014 6. Where in the body is the transitional epithelium located? (A) (B) (C) (D) 7. Which of the following is NOT primarily composed of connective tissue? (A) (B) (C) (D) 8. fat bone heart hyaline cartilage The tissue that can be classified as specialized connective tissue is (A) (B) (C) (D) 9. in the oral cavity in the urinary tract in the respiratory air sacs lining the ducts of sweat glands blood loose connective tissue dense regular connective tissue dense irregular connective tissue What type of tissue is a tendon composed of? (A) (B) (C) (D) mucous connective tissue dense regular connective tissue loose irregular connective tissue dense irregular connective tissue 10. Which of the following is composed of smooth muscle? (A) (B) (C) (D) heart biceps muscle upper esophagus wall of blood vessels CONFIDENTIAL/3 FBHS/MLD2122/AUG2014 Figure 1 11. Name the dark divisions or connections between the cell fibers in Figure 1. (A) (B) (C) (D) neuron striations neuroglia intercalated discs Figure 2 12. Identify the tissue type in Figure 2. (A) (B) (C) (D) cartilage cardiac muscle smooth muscle skeletal muscle 13. Which of the following is found in the peripheral nervous system? (A) (B) (C) (D) microglia astrocytes Schwann cells oligodendrocytes CONFIDENTIAL/4 FBHS/MLD2122/AUG2014 14. What are the supporting cells in the central nervous system called? (A) (B) (C) (D) ganglion neuroglia basket cells satellite cells 15. The cell body of a neuron is called the (A) (B) (C) (D) axon dendrite perikaryon synaptic terminal 16. Which of the following is CORRECTLY matched? (A) (B) (C) (D) trachea - hyaline cartilage C-shaped alveoli - stratified squamous epithelium bronchioles - hyaline cartilage as irregular plates bronchi - simple columnar epithelium with Clara cells 17. Which of the following is MISMATCHED? (A) (B) (C) (D) type I pneumocyte – remove pulmonary surfactant type II pneumocyte – secretes pulmonary surfactant alveolar macrophage – involved in gaseous exchange dust cell – remove inhaled particulates that reach the alveolus 18. The epithelial lining of a trachea is which of the following tissue types? (A) (B) (C) (D) transitional simple columnar simple squamous ciliated pseudostratified 19. The following statements about the stomach is true EXCEPT (A) (B) (C) (D) The folds of the stomach are called rugae. The outermost layer is coated with a serosa. The muscularis externa is composed of two layers. Mucous neck cells are present in the upper parts of gastric glands. CONFIDENTIAL/5 FBHS/MLD2122/AUG2014 20. What type of muscle makes up the muscularis externa in the esophagus? (A) (B) (C) (D) cardiac smooth striated both B and C 21. The organ that has a mucosa lined by non-keratinized stratified squamous epithelium is the (A) (B) (C) (D) stomach esophagus large intestine small intestine 22. Which is the FALSE statement about the ureter and urinary bladder? (A) (B) (C) (D) Both lack a muscularis mucosae. Both are lined by transitional epithelium. Both have an adventitia covering parts of its organs. Both have a muscularis that is arranged as an inner circular layer and an outer longitudinal layer of smooth muscle. 23. What is a glomerulus? (A) (B) (C) (D) capillary tuft efferent arteriole afferent arteriole peritubular capillaries 24. The foot processes on podocytes is the (A) (B) (C) (D) pedicel renal corpuscle parietal layer of Bowman’s capsule visceral layer of Bowman’s capsule 25. What is the cavity within the secondary follicle in the ovary? (A) (B) (C) (D) antrum zona pellucida granulosa cells Graafian follicle CONFIDENTIAL/6 FBHS/MLD2122/AUG2014 26. Which stage of the follicle is marked by the surrounding of flattened (squamous) follicular cells becoming cuboidal? (A) (B) (C) (D) primary follicle Graafian follicle secondary follicle primordial follicle 27. Which structure contains the oocyte? (A) (B) (C) (D) cortex follicle medulla corpus luteum 28. Which cells produce the male sex hormone testosterone? (A) (B) (C) (D) Sertoli cells Leydig cells interstitial cells Both A and B Figure 3 29. Figure 3 is a part of the seminiferous tubule. Identify the histological feature shown by the arrow. (A) (B) (C) (D) distal tubule uterine gland smooth muscle proximal tubule CONFIDENTIAL/7 FBHS/MLD2122/AUG2014 30. Which of the following is NOT considered a part of the wall of the seminiferous tubule? (A) (B) (C) (D) basal lamina tunica propria tunica albuginea semineferous epithelium CONFIDENTIAL/8 FBHS/MLD2122/AUG2014 SECTION B : SHORT ANSWER QUESTIONS (30 MARKS) ANSWER ALL QUESTIONS 1. With the aid of drawings, compare the THREE (3) different types of muscle tissue and state their locations. (10 Marks) 2. a. Draw, label and describe the structural differences between unilocular and multilocular adipose tissue. (6 Marks) b. State the TWO (2) functions of adipose tissue. (2 Marks) c. What happens to the fat cells when a person gains or losses weight? (2 Marks) 3. a. Identify TWO (2) major functions of the respiratory system. (2 Marks) b. Briefly relate the histological features that allow it to perform these functions. (3 Marks) c. Describe how the various features of the conducting portion change from the trachea to terminal bronchioles. (5 Marks) i. Epithelium ii. Goblet cells iii. Cartilage iv. Smooth muscle v. Elastic fibres CONFIDENTIAL/9 FBHS/MLD2122/AUG2014 SECTION C : ESSAY QUESTIONS (40 MARKS) ANSWER TWO (2) QUESTIONS ONLY Question 1 With the aid of diagrams and labelling of various types of epithelial tissue, provide descriptions of each and explain their functions. (20 Marks) Question 2 Draw and explain the THREE (3) types of neuron, and then discuss on the neuroglial cells and provide examples. (20 Marks) Question 3 Describe in detail the renal corpuscle of a nephron. (20 Marks) END OF QUESTION PAPER CONFIDENTIAL/10
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