INDEX Aekermann, W. Wilbur, 71 Adjuvant, aluminum, factors affecting efficiency of, in diphtheria and tetanus toxoids, 301 Agglutination of human red blood cells, effect of ficin on, 192 Allergic encephalomyelitis, after the excision of the injection site of antigen-adjuvant emulsion, 454 Aluminum phosphate, purification of influenza viruses by adsorption on, 155 Anaphylactic shock, factors determining decrease of complement activity in, 85 Anthrax, studies on immunity in, 129 Antibody patterns, poliomyelitis, in natives of Tahiti and Raiatea, 249 - - production by thymus and Peyer's patches, 203 Antigenicity of fl-propiolactone inactivated virus vaccines, 123 Antiglobulin serum, reaction between normal human red blood cells and, 423 Antitoxin, diphtheria, immunologic properties of a form of, 105 , , in vitro production by tissues of immunized animals, 214 Auerbach, Sidney, 129 Azoproteins, metabolic fate of isotopically labelled, 417 Bachtold, J. G., 475 Bacillus anthracis, immunizing activity of pro- tective antigen against, 129 tularense, electron microscopically revealed structural elements of, 7 Bachrach, H. L., 186 Bell, E. J., 57 Bennett, Blair M., 239 Berg, Gerald, 410 Bernet, Carl P., 330 Bernstein, Alan, 377, 386 Blood cells, human red, effect of ficin on agglutination of, 192 Bolyn, A. E., 441,450 Boyden, Stephen V., 15, 22 Bubel, H. C., 475 Bunyamwera virus, hemagglutinins of, 470 Bacterium Cadilek, Arthur E., 308 Cairns, H. J. F., 326 Callis, J. J., 186 Canine kidney, antigenic composition of structures of, 96 Cheever, F. Sargent, 161 Chin, Paul H., 321 Clarke, D. H., 470 Clostridium welchii type A theta toxin, purification of, 50 Coleman, V. R., 28 Complement activity, factors determining the decrease in, in anaphylactic shock, 85 - - fixation, kinetic studies on, 137, 146 , reaction stages in, 63 --, use of antigen prepared by desoxycholate extraction in, 348 --, human, studies on inactivation by plasmin and antigen antibody aggregates, 63 Crocker, T. Timothy, 239 Cytopathogenic effects of antiserum to human malignant epithelial cells on HeLa cell culture, 478 - - Davenport, F. M., 401 De Boer, Carl J., 308 Dicumarol, inhibition of local Shwartzman reaction by, 167 Dimethylbenzimidazole, 2,5, prevention of virus interference by, 43 Diphtheria antitoxin, immunologic properties of a form of, 105 , in vitro production of by immunized animal tissue, 214 - - toxin and toxoid in the study of delayed hypersensitivity in man, 259 toxoid, factors affecting efficiency of aluminum adjuvant in, 301 Double diffusion, specific precipitation in egg white by, 367 Downs, Cora M., 35 - - Egg white, studies on, 367 Eichbaum, F., 167 Electron microscopy of Bacterium tularense, 7 i~lectrophoretic examinations of thyroid extracts, 291 Encephalomyelitis, allergic, after the excision of the injection site of antigen adjuvant emulsion, 454 485 486 INDEX --, growth of in murine nervous tissue tumors, 134 - - virus, mouse, growth curves of, 410 Enders, John F., 391 Epilepsy, absence of neutralizing antibodies against WEE in sera of children with, 330 Farber, Miriam B., 112 Favour, Cutting B., 209 Fevurly, James, 35 Fiein, effect on agglutination of human red blood cells, 192 Francis, T., Jr., 401 Freund, Jules, 454 Friedberg, Wallace, 315 Gamma globulin, poliomyelitis antibodies in, 178 Gebhardt, L. P., 475 Gel precipitin patterns of PasteureUa pestis, role of serum proteins in, 265 Ginsberg, Harold S., 430 Goodman, Morris, 96 Greenspon, Seymour A., 96 Hale, William M., 203 Harris, Susanna, 112 Harris, T. N., 112 Hartman, Frank W., 123 Haurowitz, Felix, 315, 417 HeLa cell culture, cytopathogenic effect of antiserum to human malignant epithelial cells on, 478 Hemagglutination inhibition, studies on, 35 - - test, Middlebrook-Dubos, 22 , tannic acid, 15 Hemagglutinins of Semliki Forest and bunyamwera viruses, 470 Hennessy, A. V., 401 Herpes simplex, studies on, 28 Hess, W. R., 186 Hill, Betsy M., 137, 146 Histoplasmosis, experimental in mice, 1, 57 I-Ioggan, M. D., 265 Horstmann, Dorothy M., 249 Hyperimmune antiserum, use in experimental Western equine encephalomyelitis, 308 Hypersensitivity in man, delayed; diphtheria toxin and toxoid in the study of, 259 - - - - mice with experimental histoplasmosis, 1 Immunity, cellular, of monkeys versus antibody titers after oral inoculation with poliomyelitis virus, 475 voL. 75 in anthrax, studies on, 129 Immunoehemieal studies on blood groups, 171 Immunoelectrophoretie analysis, specific precipitation in egg white by, 367 Immunologic comparison of strains of herpes simplex, 28 - - properties of a non-precipitating diphtheria antitoxin, 105 --reactions, role of structural elements of Bacterium tularense in, 7 - - studies with fractions of Treponema paUidum, 348 Influenza viral pneumonia in mice, suppression of by xerosin, 430 viruses, differentiation and purification of, 155 virus, growth curves of, 410 , multiplicity reactivation of, 326 ---, studies of antibodies to strains of in postepidemic sera, 401 Intraocular transplants, 203 Isotope tagged tuberculin, in rive uptake of by leukocytes, 209 Isotopically labelled proteins, metabolic fate of, 417 -- Jawetz, E., 28 Jensen, Keith E., 71 Jocheim, Kurt-Alphonse, 410 Jones, Alan Richardson, 423 Kabat, Elvin A., 171 Kalter, Seymour S., 410 Kaminski, Marie, 367 Kamitsuka, Paul, 356 Kaplan, William, 225 Kibrick, Sidney, 391 Kidney, canine, antigenic composition of structures of, 96 Kinetic studies of complement fixation, 137, 146 Kraft, Lisbeth M., 249 Krakower, Cecil A., 96 Krebs 2 carcinoma, interaction with meningopneumonitis virus, 377, 386 Kuhns, William J., 105 Lagerborg, Dorothy L., 134 Larson, Carl, 7 La Veck, Gerald D., 330 Lennette, Edwin H., 227 Lepow, Irwin H., 63 Leskowitz, Sidney, 171 Levine, Leo, 301 Lipton, Murray, 454 1955] INDEX Longshore, W. Allen, Jr., 227 LoGrippo, Gerald A., 123 Lymph node cells, studies on transfer of, 112 5lacris, Nicholas T., 192, 197 Magnuson, Harold J., 348 h'[akinodan, Takashi, 192, 197 McKenna, John M., 410 Meningopneumonitis virus, interaction with Krebs 2 carcinoma, 377, 386 , measurement of lethal potency of, 239 Merrill, E. R., 28 l~'IetaboIic fate of isotopieatly labelled proteins, azopmteins and azohaptens, 417 Metaxas-Buehler, M., 333 Metaxas, M. N., 333 Meyer, ~][iriazn M., 35 Miller, Herbert K., 155 ~Iinuse, Elva, 71 Morgan, Isabel Mountain, 478 Moskowitz, M., 441,450 Multiplicity reactivation of influenza virus, 326 Mumps virus in Maitland type tissue cultures, 161 Mycobacterium tuberculosis, antigens in filtrat~s of, active in Middlebrook-Dubos hemagglutination test, 22 --, antigens in filtrates of, active in tannic acid hemagglutination test, 15 - - Omi, G., 265 Opton, Edward M., 178 Organ specificity, studies on, 269, 282, 291 Osler, Abraham G., 137, 146 Ouchterlony precipitin test, interpretation of, 460 Palmer, Dan F., 225 Pappenheimer, A. M., Jr., 259 Pasteurella pestis, role of serum proteins in gelprecipitin patterns of, 265 Pearson, Harold E., 134 Peyer's patches, antibody production by, 203 Pigeon susceptibility to Western equine encephalomyelitis infection, 225 Pillemer, Louis, 50, 63 Plasmin, inactivation of human complement by, 63 Pneumonia, viral influenza in mice, suppression of by xerosin, 430 Pneumonitis virus, newborn, serologic evidence with, 71 Poliomyelitis antibodies in gamma globulin, 178 487 - - antibody patterns in natives of Tahiti and Raiatea, 249 - - virus, cellular immunity of monkeys versus antibody titers after oral inoculation with, 475 , comparative study of type 2 strains of, 356 , evaluation of roller-tube tissue culture for isolation of from feces, 391 Pond, William L., 78 Pope, Lila P., 386 Portnoy, Joseph, 348 Precipitin reaction of blood group B substances with human anti-B produced by isoimmunization of pregnancy, 171 test, Ouchterlony, interpretation of, 460 Presidential address, 259 Prier, James E., 410 Pringle, B. H., 460 Proteins, labelled, fate of in rats, 315 Proteins, metabolic fate of isotopically labelled, 417 - - Quail, S. F., 265 Ransom, J. P., 265 Red cells, human, reaction between antiglobulin serum and, 423 Reller, Herbert H., 417 Ribi, Edgar, 7 Rickettsia typhi, resistance of mice with experimental Histoplasmosis infection, 57 Rice, Christine E., 85 Ritts, Roy E., Jr., 209 Robbins, Frederick C., 391 Rogers, Nancy G., 78 Roller4ube tissue culture; evaluation for isolation of poliomyelitis virus from feces, 391 Rose, Noel R., 269, 282, 291 Rosenfeld, G., 167 Roth, Florence B., 50 Russ, Sudie B., 78 Salvia, S. B., 1, 57 Schlesinger, R. Walter, 155 Semliki Forest virus, hemagglutinins of, 470 Sensitivity, tuberculin, studies on cellular transfer of, 333 Serological interrelationships among thyroid extracts of various species, 282 - - specificity of thyroid extracts, 269 Serum, human, unusual hemagglutinin in, 197 - - proteins, role of in gel-precipitin patterns of Pasteurella pestis, 265 488 INDEX Shepard, Charles C., 7 Shigella treated rabbit serum, transfer of lymph node cells incubated in vitro with, 112 Shinefield, Hem3r R., 227 Shulman, Sidney, 269, 291 Schwartzman reaction, inhibition by dicumarol, 167 Sigel, M. Michael, 377,386 Silverman, Myron S., 321 Skin test for Western equine encephalomyelitis, 227 Slope assay for measurement of lethal potency of meningo-pneumonitis virus in chick embryo, 239 Smadel, Joseph E., 78 Sorkin, Ernst, 15, 22 Spanoudis, S., 167 Stavitsky, Abram B., 214 Stone, Joseph L., 301 Stoner, Richard D., 203 Stratton, F., 423 Tamm, Igor, 43 Tannic acid hemagglutination test, 15 Tetanus antitoxin, separation of, dissociated from a toxin-antitoxin, 441 , recovery from toxin-antitoxin precipitates, 441 - - toxoid, effect of whole body x-irradiation of mice on immunity to, 321 , factors affecting efficiency of aluminum adjuvant in, 301 Theiler, M., 470 Thyroid extracts, serological specificity of, 269 ultracentrifugal and electrophoretic examinations of, 291 Tissue eultures, mumps in Maitland type, 161 , roller-tube, evaluation of for isolation of poliomyelitis virus from feces, 391 culture, vesicular stomatitis virus in, 186 Toxin-antitoxin precipitates, recovery of antitoxin from, 441 Training Courses, announcement, 166 Treponema pallidum, immunologic studies with fractions of, 348 Tuberculin, isotope tagged, in vivo uptake of by leukocytes, 209 sensitivity, studies on cellular transfer of in guinea pigs, 333 Tumor inhibition by virus, 377 voL 75 - - , virus inhibition by, 386 Typhus infected animals, hemagglutination inhibiting antigen in, 35 Tyrrell, David A. J., 43 Ultracentrifugal examination of thyroid extracts, 291 Vaccines, virus, antigenicity of fl-propiolactone inactivated, 123 Vesicular stomatitis virus, growth and cytopathogenicity of, 186 Virus, bunyamwera, hemagglutinins of, 470 - - , encephalomyelitis in murine nervous tissue tumors, 134 - - , herpes simplex, 28 - - , influenza, differentiation and purification of by adsorption on aluminum phosphate, 155 , , growth curves of, 410 , , multiplicity reactivation of, 326 - - , - - ; studies of antibodies in postepidemic sera, 401 inhibition by tumor, 386 - - interference, prevention by 2,5-dimethylbenzimidazole, 43 - - , meningopneumonitis, interaction with Krebs 2 carcinoma, 377, 386 , , measurement of lethal potency of, 239 --, mouse encephalomyelitis, growth curves of, 410 - - , mumps, in Maitland type tissue cultures, 161 - - , pneumonitis, newborn, 71 - - , poliomyelitis, cellular immunity of monkeys versus antibody titers after oral inoculation with, 475 , , comparative study of type 2 strains of, 356 , , evaluation of roller tube tissue culture for isolation of from feces, 391 - - proliferation in the mouse, 410 - - , Semliki Forest, hemagglutinins of, 470 - - , tumor inhibition by, 377 vaccines, antigenicity of B-propiolactone inactivated, 123 - - , vesicular stomatitis, growth and cytopathogenicity of, 186 - - , Western equine encephalomyelitis, susceptibility of pigeon to, 225 1955] INDEX Walter, Harry, 315, 417 Walters, Shirley R., 308 Watson, Barbara K., 161 Wenner, Herbert A., 356 Western equine encephalomyelitis, absence of neutralizing antibodies against, in sera of children with epilepsy, 330 - - - - - - , skin test for, 227 , use of hyperimmune antiserum concentrates in, 308 - - - - - - virus, susceptibility of pigeon to infection with, 225 489 Wilson, M. W., 460 Wilcox, W. C., 475 Winn, John F., 225, 330 Witebsky, Ernest, 269, 282, 291 Wright, George G., 129 Wyman, Louise, 301 Xerosin, suppression of influenza virus pneumonia in mice, 430 X-irradiation of mice, effect of on immunity to tetanus toxoid, 321
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