B.6FGH: Genetic Outcomes
Mechanics of Genetics
Chromosomes – The Vehicle of Heredity
DNAinteractive – Applications
Non-Mendelian Inheritance
Part I: Chromosomes – The Vehicle of Heredity
Navigate through each module listed on the right side of the page in the section titled,
Chromosomes: The Vehicle of Heredity. Make sure to take the quiz at the bottom of the
Using Karyotypes to Predict Genetic Disorders page.
1.  Draw an illustration that identifies
the three key features scientists use
to read chromosomes.
2.  Draw an illustration of how
chromosomes move during cell division.
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B.6FGH: Genetic Outcomes
Mechanics of Genetics
Part I: Chromosomes – The Vehicle of Heredity, continued
3.  Draw an example of a karyotype pair that you matched.
4.  What is abnormal meiosis?
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5.  What is the difference between trisonomy and monosomy?
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6.  What does it mean if a chromosome experiences a deletion? __________________________________________________________________________
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7.  What does it mean if a chromosome experiences a translocation?
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B.6FGH: Genetic Outcomes
Mechanics of Genetics
Part I: Chromosomes – The Vehicle of Heredity, continued
8.  Using the information in the Molecular Genealogy module, identify and describe the
four types of DNA. Also, explain each type’s significance related to genetic outcomes.
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B.6FGH: Genetic Outcomes
Mechanics of Genetics
Part II: DNAinteractive – Applications
Open each module using the buttons at the bottom of the page. Browse through each
module using the menu at the top of the page.
1.  Explain how relationships between parents and offspring can identified through a
DNA profile. Include an illustration to support your explanation.
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2.  Copy the pedigree for the Romanov family that illustrates the inheritance of hemophilia.
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B.6FGH: Genetic Outcomes
Mechanics of Genetics
Part II: DNAinteractive – Applications, continued
3.  How was mitochondrial DNA used to help solve the mystery of Anna Anderson’s identity?
Explain and cite one specific example from the Bioservers’ Sequence Server comparisons.
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4.  Pick one topic (from the top menu) featured in the Genes and Medicine module and
summarize it, including its actual or potential significance to the field of medicine.
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5.  How can DNA analysis help experts more accurately understand human development and
populations? Explain, citing a specific example from the Human Origins module.
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B.6FGH: Genetic Outcomes
Mechanics of Genetics
Part III: Non-Mendelian Inheritance
Review each of the four lessons listed on the left side of the screen. Use the Back and Next
links at the bottom to navigate within each lesson. Skip Lesson 2: Genomic Imprinting.
1.  What causes Fragile X Syndrome? Is it inherited from the mother or father?
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2.  What are the three types of mosaicism, and what can be the outcome of each?
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One possible outcome: _____________________________________________________
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One possible outcome: _____________________________________________________
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Definition: ________________________________________________________________
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B.6FGH: Genetic Outcomes
Mechanics of Genetics
Part III: Non-Mendelian Inheritance, continued
3.  From Lesson 4, draw an illustration of mtDNA with areas of genes highlighted and
labeled.
4.  Define heteroplasmy, and explain how this affects daughter cells.
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5.  If there was a mutation in a newborrn’s mtDNA. what areas of his body would you predict
may be adversely affected by that genetic condition? List at least three areas.
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