Curriculum Vitae
PERSONAL INFORMATION
Marisa D. Farber
Marisa Diana Farber
[email protected]
http://inta.gob.ar/personas/farber.marisa/
http://www.conicet.gov.ar/new_scp/detalle.php?keywords=&id=19410&datos_academicos=yes
Sex F | Date of birth 29/07/1966 | Nationality Argentine
POSITION
Researcher of the National Institute of Agricultural Technology
(INTA). Researcher of the National Council of Scientific and
Technical Research (CONICET).
WORK EXPERIENCE
April 2016 to date
Professor
National University of Hurlingham, Hurlingham, Buenos Aires, Argentina (http://unahur.edu.ar/site/)
▪ Professor of Biotechnology at Instituto de Biotecnología. (part time)
September 1997 to date
Senior Researcher.
Biotechnology Institute, National Institute of Agricultural Technology (INTA), Independent Researcher
of CONICET(3rd step from a total of 5). Buenos Aires, Argentina
▪ PI of the research group “Molecular Parasitology”, currently composed of one researcher, three postdoc and four doctoral fellows. Focus on Vector-borne diseases of veterinary and zoonotic impact.
Goals: Rationale Vaccine design ( antigen expression in heterologous vectors) ; Diagnostic tools
(molecular diagnostic tests and recombinant proteins); Molecular epidemiology studies
(development of tools for population studies of parasites and bacteria) ; Host-Pathogen and VectorPathogen interactions ( through genomics and bioinformatics approaches)
July 2006 to date
Project Coordinator
National Institute of Agricultural Technology (INTA)
▪ Management of the Project “Bioinformatics and Statistical Genomics” within INTAs National Program
of Biotechnology. Goals: infrastructure expansion (hardware and software), human resource training.
Main Subjects: analytical tools for approaching „ big data‟ related to genomics, transcriptomics,
metagenomics, phylogenomics, system biology, genome Wide SNPs studies.
September 2011
Visiting Scientist
J. Craig Venter Institute, Rockville, MD, USA.
▪ Training in Annotation and Comparative Genomics under Dr. E. Caler supervision, from the
Eukaryotic Genomics team.
February to July, 2003
Visiting Scientist
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA.
▪ Comparative genomics of tick-borne pathogens
© European Union, 2002-2015 | europass.cedefop.europa.eu
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Curriculum Vitae
Marisa D. Farber
EDUCATION AND TRAINING
1991-1996
Doctorado de la Universidad de Buenos Aires (PhD equivalent) in
Chemistry
Universidad Nacional de Buenos Aires (UBA), Buenos Aires, Argentina
▪ Molecular Biology, Biochemistry (Signal Transduction), Parasitology. Thesis: “Signal Transduction in
Phytomonas (Plant parasite)”
1984-1990
Biochemist
Universidad Nacional del Litoral (UNL), Santa Fe, Argentina
▪ Biochemistry, Celular Biology, Physical chemistry, Clinical Microbiology, Clinical Chemistry
PERSONAL SKILLS
Mother tongue(s)
Spanish
Other language(s)
English
UNDERSTANDING
SPEAKING
Listening
Reading
C2
C2
WRITING
Spoken interaction
Spoken production
C2
C2
C2
TOEFL
Levels: A1/A2: Basic user - B1/B2: Independent user - C1/C2 Proficient user
Common European Framework of Reference for Languages
Communication skills
▪ team spirit, gained in several working experiences in Argentina and abroad (Cuba, Brazil, Mexico,
France, USA), where I interacted with other researchers and local population;
▪ good communication skills, gained through teaching, seminars & oral presentations in both National
and International workshops, courses and meetings.
Organisational / managerial skills
▪ leadership , I am currently responsible for a research team of 7 people, and also the coordinator of
a project with 30 participants.
▪ good experience in fund raising and grants management (national and international ones)
▪ good experience in institutional management gained through my participation as reviewer of grants
and fellowship programs
Job-related skills
▪ experience in animal welfare gained as member of the Institutional Committee for the Care and Use
of Experimental Animals.
ADDITIONAL INFORMATION
© European Union, 2002-2015 | europass.cedefop.europa.eu
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Curriculum Vitae
Publications
Marisa D. Farber
Selected publications in International Scientific Journals (last ten years)
Mannino MC, Rivarola M; Scannapieco AC.; González E; Farber M.; Cladera JL.;
Lanzavecchia SB. Transcriptome profiling of Diachasmimorpha longicaudata towards
useful molecular tools for population management. BMC Genomics. 2016 Oct
12;17(1):793.
Guillemi EC, de la Fourniere S, Orozco M, Peña Martinez J, Correa E, Fernandez J,
Lopez Arias L, Paoletta M, Corona B, Pinarello V, Wilkowsky SE, Farber MD. Molecular
identification of Anaplasma marginale in two authocthonous South American wild species
revealed an identical new genotype and its phylogenetic relationship with those of
bovines. Parasit Vectors. 2016 May 26;9(1):305.
Tomassone, L, Guillemi EC, Farber MD. Desarrollo de un método para el diagnóstico
molecular de enfermedades transmitidas por garrapatas. RAZyEIE 2015 Diciembre;
10(3): 8-14.
La Sala LF, Redondo LM, Díaz Carrasco JM, Pereyra AM, Farber M, Jost H, FernándezMiyakawa ME. Carriage of Clostridium perfringens by benthic crabs in a sewage-polluted
estuary.
Mar
Pollut
Bull.
2015
Aug
15;97(1-2):365-72.
doi:
10.1016/j.marpolbul.2015.05.066.
Pujadas J M., Farber M, Pointier JP, Giudici C, Wisnivesky C, Prepelitchi L. New record
for Galba neotropica (d'Orbigny, 1835) in Argentina, with a detailed analysis of its
morphology
and
molecular
characteristics,
Molluscan
Research,
DOI:
10.1080/13235818.2015.1044925. 2015.
Guillemi EC, Tomassone L, Farber MD. Tick-borne Rickettsiales: Molecular tools for the
study of an emergent group of pathogens. J Microbiol Methods. 2015 Oct 16;119:87-97.
Amadio AF, Amigo N, Puebla AF, Farber MD, Cataldi AA. Draft Genome Sequences of
Escherichia coli O157:H7 Strains Rafaela_II (Clade 8) and 7.1_Anguil (Clade 6) from
Cattle in Argentina. Genome Announc. 2015 Jun 11;3(3). pii: e00617-15.
Guillemi EC, Ruybal P, Lia V, Gonzalez S, Lew S, Zimmer P, Lopez Arias L, Rodriguez
JL, Rodriguez SY, Frutos R, Wilkowsky SE, Farber MD. Development of a multilocus
sequence typing scheme for the study of Anaplasma marginale population structure over
space and time. Infect Genet Evol. 2015 Mar;30:186-94.
Moretta R, Petrigh R, Ruybal P, Mesplet M, Wilkowsky SE, Meikle V, de Echaide ST,
Garbossa G, Farber MD.The dynamics of erythrocyte infection in bovine anaplasmosis: A
flow cytometry-based analysis. J Microbiol Methods. 2014 Sep 16;107C:47-54.
C. Thompson, M.E. Baravalle, B. Valentini, A. Mangold, S. Torioni de Echaide, P.
Ruybal, M. Farber, I. Echaide. Typification of virulent and low virulence Babesia bigemina
clones by 18SrRNA and rap-1c. Exp Parasitol. 2014 Jun;141:98-105. doi:
10.1016/j.exppara.2014.03.016.
Braicovich P, Lanfranchi A, Farber M, Marvaldi A, Luque J, Timi J. Genetic and
morphological evidence reveals the existence of a new family, genus and species of
Echinorhynchida (Acanthocephala). Folia Parasitol (Praha). 2014 Aug;61(4):377-84.
Jackson AP, Otto TD, Darby A, Ramaprasad A, Xia D, Echaide IE, Farber M, Gahlot S,
Gamble J, Gupta D, Gupta Y, Jackson L, Malandrin L, Malas TB, Moussa E, Nair M, Reid
AJ, Sanders M, Sharma J, Tracey A, Quail MA, Weir W, Wastling JM, Hall N, Willadsen
P, Lingelbach K, Shiels B, Tait A, Berriman M, Allred DR, Pain A. The evolutionary
dynamics of variant antigen genes in Babesia reveal a history of genomic innovation
underlying host-parasite interaction. Nucleic Acids Res. 2014 Jun;42(11):7113-31.
Nuñez PA, Moretta R, Ruybal P, Wilkowsky S, Farber MD.Immunogenicity of
hypothetical highly conserved proteins as novel antigens in Anaplasma marginale. Curr
Microbiol. 2014 Mar;68(3):269-77.
Nuñez PA, Romero H, Farber MD, Rocha EP. Natural selection for operons depends on
genome size. Genome Biol Evol. 2013;5(11):2242-54.
Redondo LM, Farber M, Venzano A, Jost BH, Parma YR, Fernandez-Miyakawa ME,
Sudden death syndrome in adult cows associated with Clostridium perfringens type E,
Anaerobe (2013), doi: 10.1016/j.anaerobe.2013.01.001.
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Curriculum Vitae
Marisa D. Farber
Guillemi E. , Ruybal P., Lia V., González S, Farber M, Wilkowsky SE.Multi-locus typing
scheme for Babesia bovis and Babesia bigemina reveals high levels of genetic variability
in strains from Northern Argentina. Infection, Genetics and Evolution 14 (2013) 214–222.
Nuñez PA, Soria M, Farber MD. The Twin-arginine Translocation Pathway in αproteobacteria is Functionally Preserved Irrespective of Genomic and Regulatory
Divergence. PlosOne, 2012;7(3):e33605.
Tomassone L, Nuñez P, Ceballos LA, Gürtler RE, Kitron U, Farber M.. Detection of
"Candidatus Rickettsia sp. strain Argentina"and Rickettsia bellii in Amblyomma ticks
(Acari: Ixodidae) from Northern Argentina. Exp Appl Acarol. 2010 Feb 26.
Ruybal P, Moretta R, Perez A, Petrigh R, Zimmer P, Alcaraz E, Echaide I, Torioni de
Echaide S, Kocan KM, de la Fuente J, Farber M. Genetic diversity of Anaplasma
marginale in Argentina.Vet Parasitol. 2009 May 26;162(1-2):176-80.
Wilkowsky S, MorettaR, Mosqueda J, Gil G, Echaide I, Lia V, Falcon Neri A, FlorinChristensen M, Farber M. A new set of molecular markers for the genotyping of Babesia
bovis isolates. Vet Parasitol. 2009 Apr 6;161(1-2):9-18.
Tomassone L, Nuñez P, Gürtler RE, Ceballos LA, Orozco MM, Kitron UD, Farber M.
Molecular detection of Ehrlichia chaffeensis in Amblyomma parvum ticks, Argentina.
Emerg Infect Dis. 2008 Dec;14(12):1953-5.
Bono MF, Mangold AJ, Baravalle ME, Valentini BS, Thompson CS, Wilkowsky SE,
Echaide IE, Farber MD, Torioni de Echaide SM. Efficiency of a recombinant MSA-2cbased ELISA to establish the persistence of antibodies in cattle vaccinated with Babesia
bovis. Vet Parasitol. 2008 Nov 7;157(3-4):203-10.
Wilkowsky S, Farber M., Gil G., Echaide I., Mosqueda J., Alcaraz E., Suarez C. E., and
M. Florin-Christensen. Molecular Characterization of Babesia bovis Strains Using PCR
Restriction Fragment Length Polymorphism Analysis of the msa2-a/b Genes. Ann. N.Y.
Acad. Sci. 1149: 141–144 (2008).
Moretta R., Ruybal P, Mesplet M., Petrigh R, Nuñez P, Gil G, Wilkowsky S, Garbossa G,
Farber M. Flow Cytometry to Evaluate Anaplasma marginale Parasitemia using a
Fluorescent Nucleic Acid Stain. Ann. N.Y. Acad. Sci. 1149: 111–113 (2008).
Petrigh R, Ruybal P, Thompson C, Neumann R, Moretta R, Wilkowsky S, Draghi G,
Echaide I, Torioni de Echaide S, Farber M. Molecular tools for Babesia bigemina
detection. Ann. N.Y. Acad. Sci. 1149: 155–157 (2008).
Sabio y García JV, Farber M, Carrica M, Cravero S, Macedo GC, Bigi F, Oliveira SC,
Rossetti O, Campos E. Expression of Babesia bovis rhoptry-associated protein 1 (RAP1)
in Brucella abortus S19. Microbes Infect. 2008 May;10(6):635-41.
Florin-Christensen M, Schnittger L, Dominguez M, Mesplet M, Rodríguez A, Ferreri L,
Asenzo G, Wilkowsky S, Farber M, Echaide I, Suarez C. Search for Babesia bovis
vaccine candidates. Parassitologia. 2007 May;49 Suppl 1:9-12. Review.
Wilkowsky S., Farber M., Echaide I., Mosqueda J., Alcaraz E., Suarez C., FlorinChristensen M. Taking advantage of the polymorphism of the MSA-2 family for Babesia
bovis strain characterization. Parassitologia. 2007 May;49 Suppl 1:63-6
de la Fuente J, Ruybal P, Mtshali MS, Naranjo V, Shuqing L, Mangold AJ, Rodriguez SD,
Jimenez R, Vicente J, Moretta R, Torina A, Almazan C, Mbati PM, de Echaide ST, Farber
M, Rosario-Cruz R, Gortazar C, Kocan KM.. Analysis of world strains of Anaplasma
marginale using major surface protein 1a repeat sequences. Vet Microbiol. 2007 Jan
31;119(2-4):382-90. Epub 2006 Nov.
Santangelo, MP1, Mc Intosh, D.2, Bigi, F1, Armôa2, G.R G2, Campos, A. S D 2, Ruybal
P1, Dellagostin, OA3, Mc Fadden J4, Mendum, T4, Gicquel, B5, Winter, N5, Farber M1*
and Cataldi, A1* . Mycobacterium bovis BCG as a delivery system for Rap-1 antigen from
Babesia bovis. Vaccine. 2007 Jan 22;25(6):1104-13. Epub 2006 Oct 6. (Mayo 2006). (*
Co-corresponding authors).
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Curriculum Vitae
Marisa D. Farber
Silva M, Wilkowsky S, DE Echaide ST, Farber M, Oliva A.Development of an
immunosensor for the diagnosis of bovine anaplasmosis. Ann N Y Acad Sci. 2006
Oct;1081:379-81.
André Michelon, Fabricio Rochedo Conceição, Pedro Canisio Binsfeld, Cristina Wetzel
da Cunha Douglas McIntosh, Geraldo R. G. Armôa, Adriano S. Campos, Ana Paula
Argondizzo, Marisa Farber, Johnjoe McFadden, Odir Antônio Dellagostin.
Immunogenicity of Mycobacterium bovis BCG expressing Anaplasma marginale MSP1a
antigen. Vaccine. 2006 Sep 11;24(37-39):6332-9.
Honours and awards
Academic Visitor at Department of Zoology, University of Oxford (February – March
2017), in the framework of “Implementing arrangement between the ministry of
science, technology and productive innovation of the Argentine Republic and the
European Commission for providing research opportunities in Europe for argentine
Researchers”:
Fulbright Visiting Scholar Program (Fellowship) 2002-2003.
American Society for Microbiology International Fellowship. 2003
International projects
Bilateral cooperation program CONICET/CNPq (Argentina-Brazil) “UFRGS, UENF &
INTA: research and human resources training in arthropods genomics”. (years 20142016, Argentine coordinator).
FP6-2002-INCO-DEV-1, European Comission, Research Directorate. " Epidemiology and
new generation vaccines for Ehrlichia and Anaplasma infections of ruminants". (years
2005 -2009; Argentine coordinator)
INCO Contract ICA 4-CT-2000-30032 European Comission, Research Directorate
"Development of recombinant BCG multivaccine and complementary diagnostic for
predominant Parasitic and Epizootic diseases of ruminants in Latin America”. (years
2000- 2004 ; Argentine co-coordinator).
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