Honors Anatomy & Physiology Science Curriculum Honors Anatomy & Physiology I Anatomy & Physiology Course Overview Human Anatomy and Physiology is the study of the structure and function of the human body. This course follows a sequential development of the major body systems in an organized and structured curriculum. The course is designed to give the students a selective overview of human anatomical structure and an analysis of human physiological principles. Labs will include slide work, dissection of various animals and studies of the human skeleton, muscular, nervous, and sensory organs. The course will also use computer simulated dissection. The study of the structure and function of the human body is necessary as a basic health science prerequisite. This will prepare the student for all other basic science and clinical courses. This honors course includes lectures and lab components of Anatomy and Physiology One, with a heavy emphasis on technical writing, argument prom evidence and public speaking. It will also include basic chemistry and microbiology. Topics levels of organization, chemistry, biochemistry, cells, tissues and the body systems. Aspects of disease and treatments will also be included. The student will understand the terms and concepts related to healthy human anatomy and physiology, including the body systems and what is necessary for the body to achieve and maintain a healthy state. In addition, the student will be able to list and define terms used to describe position and regions within the body. The student will have a basic understanding of concepts in chemistry and biochemistry that are essential to study of the human body. They will know about the structure, behavior, and functions of elements, atoms, molecules, compounds, and mixtures, with a special focus on water as an essential compound in all living systems. In addition, the student will be familiar with the characteristics and types of organic compounds and their composition. The student will appreciate the relevance of chemistry to health sciences and not feel intimidated by it. Students will be able to demonstrate knowledge of the structure of cells, tissues, organs, and organ systems. They will be able to explain how cells are organized in the human body and how they communicate with each other. Students through interactive Anatomy will be able to use: Illustrated Anatomy Cadaver Practical Students will be able to use a microscope to identify cells and tissues of different systems. Students will be able to identify the major tissue groups of the body and describe their location and function. Students will be able to create written records of their findings and provide presentations to share their findings and argue their position. 2 Anatomy & Physiology Pacing Guide Unit 1 Life, organization, chemistry, cells, and tissues 30 days Unit 2 Tissues and the integument 40 days Unit 3 Skeletal and Muscular systems 50 days Unit 4 Nervous and special senses 40 days Review 15 days Review Student Learning Objectives Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms. [Clarification Statement: Emphasis is on functions at the organism system level such as nutrient uptake, water delivery, and organism movement in response to neural stimuli. An example of an interacting system could be an artery depending on the proper function of elastic tissue and smooth muscle to regulate and deliver the proper amount of blood within the circulatory system.] [Assessment Boundary: Assessment does not include interactions and functions at the molecular or chemical reaction level.] (HS-LS1-2) Plan and conduct an investigation to provide evidence that feedback mechanisms maintain homeostasis. [Clarification Statement: Examples of investigations could include heart rate response to exercise, stomata response to moisture and temperature, and root development in response to water levels.] [Assessment Boundary: Assessment does not include the cellular processes involved in the feedback mechanism.] (HS-LS1-3) Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells. [Assessment Boundary: Assessment does not include identification of specific cell or tissue types, whole body systems, specific protein structures and functions, or the biochemistry of protein synthesis.] (HS-LS1-1) Modifications for differentiation at all levels Teacher Note: Teachers identify the modifications that they will use in the unit. Restructure lesson using UDL principals (http://www.cast.org/our-work/about-udl.html#.VXmoXcfD_UA) ● Structure lessons around questions that are authentic, relate to students’ interests, social/family background and knowledge of their 3 Anatomy & Physiology community. ● Provide students with multiple choices for how they can represent their understandings (e.g. multisensory techniques-auditory/visual aids; pictures, illustrations, graphs, charts, data tables, multimedia, modeling). ● Provide opportunities for students to connect with people of similar backgrounds (e.g. conversations via digital tool such as SKYPE, experts from the community helping with a project, journal articles, and biographies). ● Provide multiple grouping opportunities for students to share their ideas and to encourage work among various backgrounds and cultures (e.g. multiple representation and multimodal experiences). ● Engage students with a variety of Science and Engineering practices to provide students with multiple entry points and multiple ways to demonstrate their understandings. ● Use project-based science learning to connect science with observable phenomena. ● Structure the learning around explaining or solving a social or community-based issue. ● Provide ELL students with multiple literacy strategies. ● Collaborate with after-school programs or clubs to extend learning opportunities. Educational Technology Standards: 8.1.12.A.1, 8.1.12.A.2, 8.1.12.B.2, 8.1.12.C.1, 8.1.12.D.1, 8.1.12.D.2, 8.1.12.D.3, 8.1.12.E.1, 8.1.12.F.1 Technology Operations and Concepts • Create a personal digital portfolio which reflects personal and academic interests, achievements, and career aspirations by using a variety of digital tools and resources •Produce and edit a multi-page digital document for a commercial or professional audience and present it to peers and/or professionals in that related area for review. Creativity and Innovation • Apply previous content knowledge by creating and piloting a digital learning game or tutorial. Communication and Collaboration • Develop an innovative solution to a real world problem or issue in collaboration with peers and experts, and present ideas for feedback through social media or in an online community. 4 Anatomy & Physiology Digital Citizenship • • • Demonstrate appropriate application of copyright, fair use and/or Creative Commons to an original work. Evaluate consequences of unauthorized electronic access and disclosure, and on dissemination of personal information. Compare and contrast policies on filtering and censorship both locally and globally. Research and Information Literacy • Produce a position statement about a real world problem by developing a systematic plan of investigation with peers and experts synthesizing information from multiple sources. Critical Thinking, Problem Solving, Decision Making • Evaluate the strengths and limitations of emerging technologies and their impact on educational, career, personal and or social needs. Career Ready Practices Career Ready Practices describe the career-ready skills that all educators in all content areas should seek to develop in their students. They are practices that have been linked to increase college, career, and life success. Career Ready Practices should be taught and reinforced in all career exploration and preparation programs with increasingly higher levels of complexity and expectation as a student advances through a program of study. CRP1. Act as a responsible and contributing citizen and employee - Career-ready individuals understand the obligations and responsibilities of being a member of a community, and they demonstrate this understanding every day through their interactions with others. They are conscientious of the impacts of their decisions on others and the environment around them. They think about the near-term and long-term consequences of their actions and seek to act in ways that contribute to the betterment of their teams, families, community and workplace. They are reliable and consistent in going beyond the minimum expectation and in participating in activities that serve the greater good. CRP2. Apply appropriate academic and technical skills - Career-ready individuals readily access and use the knowledge and skills acquired through experience and education to be more productive. They make connections between abstract concepts with real-world applications, and they make correct insights about when it is appropriate to apply the use of an academic skill in a workplace situation. CRP4. Communicate clearly and effectively and with reason - Career-ready individuals communicate thoughts, ideas, and action plans with clarity, 5 Anatomy & Physiology whether using written, verbal, and/or visual methods. They communicate in the workplace with clarity and purpose to make maximum use of their own and others’ time. They are excellent writers; they master conventions, word choice, and organization, and use effective tone and presentation skills to articulate ideas. They are skilled at interacting with others; they are active listeners and speak clearly and with purpose. Career-ready individuals think about the audience for their communication and prepare accordingly to ensure the desired outcome. CRP5. Consider the environmental, social and economic impacts of decisions - Career-ready individuals understand the interrelated nature of their actions and regularly make decisions that positively impact and/or mitigate negative impact on other people, organization, and the environment. They are aware of and utilize new technologies, understandings, procedures, materials, and regulations affecting the nature of their work as it relates to the impact on the social condition, the environment and the profitability of the organization. CRP6. Demonstrate creativity and innovation - Career-ready individuals regularly think of ideas that solve problems in new and different ways, and they contribute those ideas in a useful and productive manner to improve their organization. They can consider unconventional ideas and suggestions as solutions to issues, tasks or problems, and they discern which ideas and suggestions will add greatest value. They seek new methods, practices, and ideas from a variety of sources and seek to apply those ideas to their own workplace. They take action on their ideas and understand how to bring innovation to an organization. CRP7. Employ valid and reliable research strategies - Career-ready individuals are discerning in accepting and using new information to make decisions, change practices or inform strategies. They use reliable research process to search for new information. They evaluate the validity of sources when considering the use and adoption of external information or practices in their workplace situation. CRP8. Utilize critical thinking to make sense of problems and persevere in solving them - Career-ready individuals readily recognize problems in the workplace, understand the nature of the problem, and devise effective plans to solve the problem. They are aware of problems when they occur and take action quickly to address the problem; they thoughtfully investigate the root cause of the problem prior to introducing solutions. They carefully consider the options to solve the problem. Once a solution is agreed upon, they follow through to ensure the problem is solved, whether through their own actions or the actions of others. CRP9. Model integrity, ethical leadership and effective management - Career-ready individuals consistently act in ways that align personal and community-held ideals and principles while employing strategies to positively influence others in the workplace. They have a clear understanding of integrity and act on this understanding in every decision. They use a variety of means to positively impact the directions and actions of a team or organization, and they apply insights into human behavior to change others’ action, attitudes and/or beliefs. They recognize the near-term and longterm effects that management’s actions and attitudes can have on productivity, morals and organizational culture. CRP10. Plan education and career paths aligned to personal goals - Career-ready individuals take personal ownership of their own education and 6 Anatomy & Physiology career goals, and they regularly act on a plan to attain these goals. They understand their own career interests, preferences, goals, and requirements. They have perspective regarding the pathways available to them and the time, effort, experience and other requirements to pursue each, including a path of entrepreneurship. They recognize the value of each step in the education and experiential process, and they recognize that nearly all career paths require ongoing education and experience. They seek counselors, mentors, and other experts to assist in the planning and execution of career and personal goals. CRP11. Use technology to enhance productivity - Career-ready individuals find and maximize the productive value of existing and new technology to accomplish workplace tasks and solve workplace problems. They are flexible and adaptive in acquiring new technology. They are proficient with ubiquitous technology applications. They understand the inherent risks-personal and organizational-of technology applications, and they take actions to prevent or mitigate these risks. CRP12. Work productively in teams while using cultural global competence - Career-ready individuals positively contribute to every team, whether formal or informal. They apply an awareness of cultural difference to avoid barriers to productive and positive interaction. They find ways to increase the engagement and contribution of all team members. They plan and facilitate effective team meetings. Unit Sequence Part A- Storyline: An object from space fell on your school territory, as future scientists you and your classmates are assigned to investigate the content of the object and determine if the object shows characteristics of life Overarching Question: Why some organisms show only some characteristics of life and others show all of them? Concepts Formative Assessment • All living organisms are identified by their ability to carry out characteristics of life processes ✓ There are six characteristics of living organisms • All organisms carry on certain processes that distinguish them from nonliving objects Students who understand the concepts are able to: • Collect empirical evidence about the main characteristics of living organisms. • Collect empirical evidence about cell structures as the smallest unit capable to carry all of the life functions. • Use empirical evidence from experiments and other scientific reasoning to support oral and written arguments that explain the relationship among all cell organisms and their living characteristics 7 Anatomy & Physiology • The main life processes in humans are metabolism, responsiveness, movement, growth, differentiation, and reproduction. Learning Objective and Essential Questions Standard 1. Identify the main characteristics of living organisms. 2. Analyze the characteristics of living organisms in single cell organism and multicellular organisms. HS-LS1-2 What are the main characteristics of living organisms? Can single cell organisms carry out all of the characteristics of living organisms? Do multicellular organisms show all of the characteristics of life? Sample Activities Resources Lab-Life: Common Characteristics Probing levels of life- Lab: Life: Common Characteristics; Students will investigate the structure, function, development, heredity, and evolution of organisms. Timeline 80-120 min; (In the unit folder) Students with these observations will collect data and will attempt to conclude the main characteristics of living organisms. Part B- Storyline: (Homeostasis) You are a medical student during the residency program and the doctor that you are working for asked you to provide some advice on the effects of the negative feedback on blood pressure. Overarching Question: What are some of the disruptions of homeostasis in human body? Concepts Formative Assessment • Homeostasis influence the function and development of the human body Students who understand the concepts are able to: • Conduct experiments, collect evidence, and analyze empirical data. • Factors that affect homeostasis can be more than one cause • • Homeostasis can be external, internal, psychological, and sometimes prolonged. Use evidence from experiments and other scientific reasoning to support oral and written explanations of how homeostasis influences the function of the human body. • Organisms have developed positive and negative feedback • Identify and describe possible causes and effects of positive and 8 Anatomy & Physiology mechanisms • negative feedback in organisms Some cause-and-effect relationships in homeostasis is between positive and negative feedback. Learning Objective and Essential Questions Standard Describe the role of homeostasis in human body. Compare and contrast between positive and negative feedback. LO 2.28 Use representations or models to analyze quantitatively and qualitatively the effects of disruptions to dynamic homeostasis in biological systems. (SP 1.4) LO 2.29 Create representations and models to describe immune responses. (SP 1.1, 1.2) 1) Determine the role of the positive and negative feedback mechanisms in maintain the homeostasis. 2) Analyze the role of homeostasis in human What is homeostasis? What is a feedback system? How are positive and negative feedback related to homeostasis? Why do positive feedback systems that are part of the normal physiological response include some mechanisms that terminate the system? Sample Activities Resources Lab67-Response of Multicellular Animals to Light Students will analyze the phototoxic behavior of several multicellular animals by using beams of unfiltered and filtered light. Probing levels of life- Lab: Response of Multicellular Animals to Light; Timeline 100-120 min; (In the unit folder) 9 Anatomy & Physiology body. (HS-LS1-3) Part C- Storyline: (Chemistry) Essential fatty acids such as (EFA’s) cannot be made by the human body they must be obtained by foods or supplements. As a biochemist you are assigned to write a detailed report on the role of (EFA’s) and determine which way is more efficient. Overarching Question: What is the role that macromolecules such as proteins, carbohydrates, and lipids play on human body Concepts Formative Assessment Macromolecules are large structures built from smaller, building Students who understand the concepts are able to: block molecules. Describe the importance of carbon in day to day functions of a Polymers, such as carbohydrates, lipids, and nucleic acids, are living organism. arranged from smaller, monomers. Identify the 4 main macromolecules by examining their Dehydration Synthesis involves the linking of a monomer to a structures. polymer, and the expulsion of H20. Determine whether an unknown lipid is saturated or Enzymes play a crucial role in human body. unsaturated. Buffer systems are made of acidic and basic ends. Using different indicators, determine what organic compound Learning Objective and Standard Essential Questions is present in a solution. Sample Activities Resources 10 Anatomy & Physiology Analyze how the subcomponents of biological molecules and their sequence determine the properties of that molecule. What type of chemical reactions happen in the human body? Determine how buffers work in human body and what is their role to maintain homeostasis As a soft organic matter what are the main organic compounds that made up our body? Identify the function of the 4 main macromolecules by examining their structures. How are complex molecules such as carbohydrates, proteins, lipids, DNA, RNA, and ATP formed in our body? Identify the types of chemical reactions that happen in the human body (HS-LS1-1) What is a buffer system? What is the role of buffers in our body? Lab8-Extracellular Enzymes : Students will determine the role that enzymes play in biochemical processes Lab 6-Molecules of Biological Importance; Students will build the three-D structure of the molecules and understand how these molecules function and how they interact with one another Probing Levels of Life -Lab: Extracellular Enzymes; timeline 80100 min; (unit folder) Probing Levels of Life-Lab 6Molecules of Biological Importance; timeline 80-100 min; in the unit folder Probing Levels of Life-lab 7-Amino Acid Chromatography; Timeline 100120 min; in the unit folder Lab7-Amino Acid Chromatography; students will be able to use chemistry processes to identify amino acids, which are the building blocks of proteins. What are the main reactions that happen in human body? Part D- Storyline:(cells and tissues ) You work as an intern for a U.S senator you are assigned to provide scientific prove and data for the use of the three D printing that allows the scientists to grow new tissues in laboratory to replace damaged tissues in different parts of body. Essential Question: How can biopsy be used to diagnose many disorders such as infections, inflammations, and cancers? Concepts Formative Assessment Cell Membranes are selectively permeable. Students who understand the concepts are able to: The cell membrane is composed of a phospholipid bilayer List the reasons a semi-permeable membrane in the cell is The phospholipid bilayer is described as a “Fluid Mosaic” model essential to cell functions. because it is composed of different components that can move Use dialysis tubes to describe hypotonic and hypertonic throughout the membrane. solutions. Transport Proteins lie within the phospholipid bilayer of a cell Describe the different methods of membrane transport, and membrane and aid in transport of molecules across the 11 Anatomy & Physiology membrane. Diffusion, osmosis, facilitated diffusion, and active transport are ways in which molecules move across a membrane. Enzymes lower the activation energy of reactions Enzymes are affected by environmental conditions. Cells are organized according the their function in different tissues Learning Objective and Standard Describe the process of the transport of the substances across the cell membrane. Analyze the factors that contribute to an electrochemical gradient Identify the main factors that influence the diffusion rate of substances across the cell membrane Describe the general features of connective tissues? Describe the location and function of the various types of connective tissues Analyze the main types of tissues 2.A.3 - Organisms must exchange matter with the environment to grow, reproduce and maintain which methods require an input energy, and which methods do not require an input of energy. Calculate the concentration of solutions and compare the internal and external concentrations. Describe the catalytic cycle of an enzyme. Use graphs to determine the optimal environmental conditions of an enzyme. Essential Questions Sample Activities Resources What are cells? Lab 8- Extracellular Enzymes Students will be able to identify the crucial role of the extracellular enzymes in braking down complex molecules into smaller molecules; determine the role of the these enzymes in the metabolism process. Probing Levels of Life-lab 8Extracellular Enzymes; Timeline 100120 min; in the unit folder What is the role and the function of the cell membrane? Why is the cell membrane described as semipermeable? What are the factors that contribute to the electrochemical gradient? What are the factors that influence the diffusion rate of substances across the plasma membrane? What are the four basic types of human tissues? How are connective tissues classified? What characteristics are Lab9- Quantitative and Qualitative Plasmolysis Students will observe the quantitative effects of the plasmolysis in Elodea cells and quantitatively measure the rate plasmolysis in potato slides. Probing Levels of Life-lab 9Quantitative and Qualitative Plasmolysis.; Timeline 100-120 min; in the unit folder Probing Levels of Life-lab 10-Basic Cell Structure; Timeline 100-120 min; in the unit folder Lab10-Basic Cell Structure Students will be able to observe and locate parts 12 Anatomy & Physiology organization. 2.B.1 - Cell membranes are selectively permeable due to their structure. common for all epithelial tissues? within several types of cells; measure the length width of each type of cell in micrometer 2.B.2 - Growth and dynamic homeostasis are maintained by the constant movement of molecules across membranes. 2.B.3 - Eukaryotic cells maintain internal membranes that partition the cell into specialized regions. 4.B.1 - Interactions between molecules affect their structure and function. (HS-LS1-2) Unit Project/Lab Performance/Assessments Student physician diagnosis with written report and presentation Vocabulary Cell organism DNA homeostasis Fats protein Amino acids tissues organs Organs systems pH Feedback mechanism; pH scale Enzymes 13 Anatomy & Physiology Unit 2 Sequence Part A- Storyline: (Organization of the body systems) You are working as an intern in the radiology department and in the next couple of weeks you will perform proton beam therapy for several cancer patients. Proton beam therapy is a new and innovative treatment that focuses in destroying cancer cells in the brain without having surgical intervention on the cranial cavity. Your job is to provide the patient with the information on how the proton beam therapy works, what it is, and the positive effect on using the beam proton therapy vs surgery. Overarching Question: What role do body plains, cavities and regions play on medical imaging procedures Concepts Formative Assessment • The Human body consist of eleven systems Skeletal, muscular, nervous, endocrine, respiratory, cardiovascular, digestive, reproductive, urinary, lymphatic, integumentary systems The plains that go through the human body are frontal, transverse, sagittal, and oblique. Students who understand the concepts are able to: Body cavities help protect, separate, and support internal organs Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms. Communicate scientific and technical information about why the molecular-level structure is important in the functioning of designed materials. The main body cavities are: a) b) c) d) e) Cranial cavity Vertebral cavity Thoracic cavity Abdominal cavity Pelvic cavity Body regions and quadrants are used in medical field to locate specific structures. Learning Objective and Standard Identify the role of body cavities, Conduct experiments, collect evidence, and analyze empirical data. Use evidence from experiments and other scientific reasoning to support oral and written explanations of how homeostasis influences the function of the human body. Identify and describe possible causes and effects of positive and negative feedback in organisms Essential Questions Sample Activities Resources Lab-15 Surface Anatomy and Laboratory manual for Anatomy What are the main body 14 Anatomy & Physiology regions and plains Describe the principals and importance of medical imaging procedures in the evaluation of organ functions and diagnosis of diseases Describe the anatomical positioning Relate the anatomical names and corresponding common names for various regions of the human body plain What are the main regions of the human body What role do body plains, cavities, and regions play on medical imaging procedures? What are the main systems of the human body What is a system, organ, tissue and body systems Body Plains Students will identify the importance of the surface anatomy of the face, chest, back, abdomen, shoulder, arm, thigh, and leg. and physiology – Lab 15:Surface Anatomy and Body Plains; Timeline 100-180 min; (In the unit folder) Students identify body plains, regions and cavities SI-H-A6 Communicating and defending a scientific argument; SIH-B1 Communicating that scientists usually base their investigations on existing models; SI-H-B2 Communicating that scientists conduct investigations for a variety of reasons, such as exploration of new areas, discovery if new aspects of the natural world, confirmation of prior investigations, evaluation of current theories, and comparison of models and theories; and SI-H-B3 Communicating that scientists rely on technology to enhance the gathering and manipulation of ideas. 15 Anatomy & Physiology LS-H-A3 Investigating cell differentiation and describing stages of embryonic development of representative organisms. (HS-LS1-2), (HS-LS1-3) Part B- Storyline:(Integumentary System) Many Infants during their first months of their life gain a lot of weight as a result they are diagnosed with a condition known as Rakidi which is softening of the bones. As a pediatrician explain to a young mother what is causing this condition to her first new born and what medication would you describe to regulate the condition. Overarching Question: Why it is difficult to save the life of someone with extensive third -degree burn? Concepts Formative Assessment The integumentary system plays a crucial role in homeostasis by Students who understand the concepts are able to: protecting the body and helping regulate body temperature Describe the role of the integumentary system in regulating The integumentary system allows us to sense pleasure, pain, and body temperature, store blood, protect body from external external stimuli environment, detect courteous sensations, excrete and absorbs The Skin is made of two main parts epidermis and dermis. substances, and synthesizes vitamin D. Epidermis cells consist of keratinocytes, melanocytes, Identify the 2 main parts of the skin. Langerhans, and Markel cells. Analyze the structure of the epidermis and dermis. The epidermal cells are organized in layers stratum Basale, Using a dichotomous key to differentiate layers and structures spinosum, granulosum, and lucidum. of epidermis and dermis. Dermis consist of connective tissue containing collagen and Analyze the causes of skin color. elastic fibers Dermis is divided in papillary and reticular regions The color of the skin is due to melanin, carotene, and hemoglobin. Learning Objective and Essential Questions Sample Activities Resources Standard Analyze the role that the What is the main function of Lab7-Integumentary system Integumentary System structure and integumentary system plays in 16 Anatomy & Physiology homeostasis. Determine the function and role that the Integumentary system. Identify the function of the 2 main parts of the integumentary system. Identify the types of cells and layers that make us the epidermis and dermis. Analyze the three main skin colors and determine the factors that influence the skin color. SI-H-A6 Communicating and defending a scientific argument; SI-H-B1 Communicating that scientists usually base their investigations on existing models; SI-H-B2 Communicating that scientists conduct investigations for a variety of reasons, such as exploration of new areas, discovery if new aspects of the natural world, confirmation of prior investigations, evaluation of current theories, and comparison of models and theories; and SI-HB3 Communicating that scientists rely on technology to enhance the gathering and manipulation the skin? structure and function: What role does the integumentary system plays in maintaining homeostasis? Students will be able to describe the function of the integumentary system; Identify layers of the epidermis and dermis and identify the accessory structures of the skin under the microscope. What are the two main parts that make up the integumentary system? What embryonic cells contribute to the development of epidermis and dermis Structure and Function: Stem Cell: Students will evaluate the validity and reliability of and/or synthesize multiple claims, methods, and/or designs that appear in scientific and technical texts or media reports, verifying the data when possible. function-Lab: Identification of skin Layers and Accessory Structures; timeline 120-180 min; (find the Lab packet in the unit folder) Structure and Function-Lab: Stem Cells; Timeline 120-180 min; ( find the Lab packet in the unit folder) Histology-World! Histology PracticalIntegumentary System: Virtual Lab; www.histologyworld.com/practical/skin/skin.htm; Timeline 160-180 min; (find the Lab packet in the unit folder) Virtual Lab-Histology PracticalIntegumentary System Students will analyze and interpret different microscope slides and determine types of skin cells. 17 Anatomy & Physiology of ideas. LS-H-A3 Investigating cell differentiation and describing stages of embryonic development of representative organisms. (HS-LS1-2), (HS-LS1-3) Unit Project/Lab Performance/Assessments Student physician diagnosis with written report and presentation Vocabulary Body cavities Cranial cavity Vertebral canal Body Plains Thoracic cavity Epidermis Abdominal cavity Cranial cavity Dermis Sebaceous glands Hypodermis Adipose tissue Subcutaneous layer Pacinian corpuscles Meissner corpuscle Cutaneous plexus Unit 3 Sequence Part A- Storyline: (Skeletal System) You and your team are writing a research article in a new and innovative approach on bone fusion without using screws. Please explain what data did you collected during the research and the benefit of using bone fusion rather than screws for a bone fracture. Overarching Question: how does the bone tissue contributes to homeostasis of the human body? Concepts Formative Assessment 18 Anatomy & Physiology • There are 206 bones in the human body. Compare and contrast female and male skeletal system. • The skeletal system performs six main functions. • There are four types of cells in the bone tissue: Osteogenic, osteoblast, osteocytes, osteoclasts cells. Identify different types of the bone cells on the photomicrograph or microscope. • There are three factors that affect the bone growth a. Mineral b. Vitamins c. Hormones The skeletal system consists of: the axial, and appendicular skeleton. Describe the six main functions of the skeletal system. Analyze the function of the bones and skeletal system. Describe and identify the structure and function of each part of the long bone. Identify the role of the skeletal system in maintain the homeostasis. Identify the factors that influence the bone growth. Cranial bones, Thoracic bones and Vertebral bones make up the axial. The appendicular system consists of pectoral girdle, upper limb, pelvic girdle, lower limb. Learning Objective and Essential Questions Standard Describe how the skeletal system is What is the main function of organized into axial and the skeletal system appendicular divisions. What role does the skeletal system plays in maintaining Classify bones according to their the homeostasis shape or location. How can we tell if we are viewing a bone cell under Identify the location and surface the microscope features of the parietal, occipital, What is a bone sphenoid, ethmoid, bones. How do bones grow and develop Describe the structure and the function of the vertebral column in various regions. Sample Activities Resources Lab 8- Laboratory Manual for Anatomy and Physiology: Bone Structure and Function Laboratory Manual for Anatomy and Physiology :Bone Structure and Function-Lab; Timeline 80-120 min; (In the unit folder) Students will classify different bodes as long, short, flat, irregular or sesamoid. Students will identify different microscopic slides and determine what part of the bone the cells came from. Lab 9- Laboratory Manual for Anatomy and Physiology: Axial Laboratory Manual for Anatomy and Physiology: Axial Skeleton-Lab; Timeline 200-250 min; (in the unit folder) Laboratory Manual for Anatomy and Physiology: Appendicular Skeleton-Lab; Timeline 200-250 min; (in the unit folder) 19 Anatomy & Physiology Skeleton. Identify the bones of the pectoral and pelvic girdle, their functions and their principal markings. Identify the bones of the upper, lower limbs and their principal markings. Students will identify the three main parts of the Axial Skeleton and identify the major bones that make up the axial skeleton. Laboratory Manual for Anatomy and Physiology: Joints and Synovial Joint Movements-Lab; Timeline 200-250 min; (in the unit folder) A. Interactive Anatomy -Illustrated Anatomy -Cadaver Practical SI-H-A6 Communicating and defending a scientific argument; SIH-B1 Communicating that scientists usually base their investigations on existing models; SI-H-B2 Communicating that scientists conduct investigations for a variety of reasons, such as exploration of new areas, discovery if new aspects of the natural world, confirmation of prior investigations, evaluation of current theories, and comparison of models and theories; SI-H-B3 Communicating that scientists rely on technology to enhance the gathering and manipulation of ideas. Lab 10- Laboratory Manual for Anatomy and Physiology: Appendicular Skeleton. LS-H-A3 Investigating cell differentiation and describing stages of embryonic development of representative organisms. C. Interactive Anatomy -Illustrated Anatomy -Cadaver Practical Students will be able to identify the bones that make appendicular Skeleton. B. Interactive Anatomy -Illustrated Anatomy -Cadaver Practical Lab 11- Laboratory Manual for Anatomy and Physiology :Joints and Synovial Joint Movements Students will be able to identify the bones that make joints and synovial joints movements (HS-LS1-2) 20 Anatomy & Physiology Part B- Storyline: (Muscular System) During a soccer game the centerfield female player had a torn ACL. As an orthopedic doctor what type of treatment do you suggest to the patient using a cadaver or cutting from the one tissue and why? Overarching Question: Why muscle cells are not able to repair? Concepts Formative Assessment • There are three types of muscular tissues: skeletal, cardiac, and smooth. Students who understand the concepts are able to: • The main function of the skeletal tissue is to produce body movement, stabilize body positions, store and move substances within the body, and generate heat. • • Muscular tissue has four special properties: electrical excitability, contractility, extensibility, elasticity. Muscles fibers have three ways to produce ATP: a) From creating phosphates b) By anaerobic cellular respiration c) By aerobic cellular respiration Learning Objective and Essential Questions Standard Describe the structure of the skeletal tissue and skeletal muscle fibers. Identify the connective tissue structures in skeletal muscle on the microscope slide or photomicrograph. Describe the structure of the sarcomere. What is the main role of muscles? How do muscle fibers function? How do muscles use ATP? What are the three main muscle fibers? What are the main major muscles of the human body? • Compare and contrast the three types of the muscular tissue by structure and by function. • Describe the role of muscles play in human body. • Differentiate between skeletal, cardiac and smooth muscles. • Analyze the way muscles produce ATP. • Explain how muscle fibers regenerate. Sample Activities Lab 12- Laboratory Manual for Anatomy and Physiology :Skeletal Muscle Structure Students will be able to: a). identify and label skeletal muscle tissue and coverings b) Identify and label skeletal Muscle fibers Resources Laboratory Manual for Anatomy and Physiology :Skeletal Muscle StructureLab; Timeline 200-250 min; (in the unit folder) Laboratory Manual for Anatomy and Physiology :Contraction of the Skeletal Muscles-Lab ; Timeline 200250 min; (in the unit folder) Laboratory Manual for Anatomy and 21 Anatomy & Physiology Describe the structure of the neuromuscular junction. Describe the role of ATP in skeletal muscle contraction. Describe the three muscle fiber types and their influence on contraction. Describe how skeletal muscles achieve a smooth sustained contraction. What is a muscle? How do muscles contract and relax? What is the structure of the muscle tissue? c) identify and label the electron micrograph of the Sarcomere d) identify and label the neuromuscular junctions Students will have an interactive anatomy review Lab 13- Laboratory Manual for Anatomy and Physiology: Contraction of the Skeletal Muscle. Describe how skeletal muscles vary the force of contraction. Students will be able to a) Calculate the percentage of skeletal muscle fibers Define threshold stimulus maximal stimulus recruitment and fatigue and explain how to observe them. b) Determine the influence of muscle fiber type on skeletal muscle contraction Identify the major skeletal muscles of the human body. c) Differentiate between isotonic and isomeric contractions Describe the function of the major skeletal muscles. d) Analyze the role of ATP in contraction of skeletal muscle fibers Label the muscles of the human body. SI-H-A6 Communicating and defending a scientific argument; SI-H-B1 Communicating that scientists usually base their investigations on existing models; SI-H-B2 Communicating that Physiology :Skeletal Muscles and their Action -Lab ; Timeline 200-250 min; (in the unit folder) Students will have an interactive anatomy review Lab 14- Laboratory Manual for Anatomy and Physiology: Skeletal Muscles and their Actions. Students will be able to: 22 Anatomy & Physiology scientists conduct investigations for a variety of reasons, such as exploration of new areas, discovery if new aspects of the natural world, confirmation of prior investigations, evaluation of current theories, and comparison of models and theories; and SI-H-B3 Communicating that scientists rely on technology to enhance the gathering and manipulation of ideas. a) Identify the major skeletal muscles b) Describe the function of the major skeletal muscles Students will have an interactive anatomy review through 1) Illustrated Anatomy 2) Cadaver Practical LS-H-A3 Investigating cell differentiation and describing stages of embryonic development of representative organisms. (HS-LS1-2), (HS-LS1-3) Vocabulary Rib Hyoid Tarsals Thoracic vertebrae Thorax Metatarsals Cranial Bones Pelvic girdle Humerus Ethmoid Bone Femur Ulna Optical Bone Patella Radius Skull Tibia Carpal 23 Anatomy & Physiology Unit Project/Lab Performance/Assessments Student physician diagnosis with written report and presentation Unit 4 Sequence Part A- Storyline: (Nervous System) You are an intern working for a US senator who wants to introduce a bill for early vaccination regarding meningitis. Your job is to provide a report that utilizes scientific data to describe the disease and current treatments and/or cures. Overarching Question: Why do we feel pain? Concepts The nervous system regulates body activities by responding rapidly using nerve impulses. Formative Assessment Students who understand the concepts are able to: Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms. Communicate scientific and technical information about why the molecular-level structure is important in the functioning of designed materials. Conduct experiments, collect evidence, and analyze empirical data. Use evidence from experiments and other scientific reasoning to support oral and written explanations of how homeostasis influences the function of the human body. Identify and describe possible causes and effects of positive and negative feedback in organisms The nervous system is responsible for: a) perception b) behavior c) memory d) And initiate all the voluntary movements The nervous system is made of two main subdivisions: central Nervous system and Peripheral nervous system, The nervous system carries out three main functions: 1. Sensory functions 2. Integrative functions 3. Motor functions Nervous tissue comprise two types of cells-neurons and neuralgia. The basic parts of the neuron are dendrites, cell body, and axon Neurons are classified according to their structure and function into: Multipolar, bipolar, and unipolar neurons; functionally they are afferent, efferent, and association neurons. 24 Anatomy & Physiology Neurons communicate by electrical and chemical synapses. The spinal cord controls some of your most rapid reactions to the environmental changes. Learning Objective and Essential Questions Standard Identify the main role of the nervous system and determine the parts of the nervous system. Classify neurons according to their structure and their function Identify unipolar, bipolar, and multipolar neurons on photomicrographs. Determine the main role of and identify the anatomical, features spinal cord. Identify the anatomical features and functions of the spinal cord transverse section on the microscope slide. Analyze the four spinal plexuses and the major nerves arising from each plexus. Identify the five components of a somatic flex. Compare and contrast how the monosynaptic and polysynaptic reflex arcs differ. What is a neuron How do neurons communicate with one another How are impulses being created How do nerve cells send and receive messages How can we tell if we are viewing a nerve cell under the microscope How is information being transmitted through the spinal cord What is a somatic reflex and how does it work What is the difference between the monosynaptic and polysynaptic reflex Sample Activities Resources Lab 16- Laboratory Manual for Anatomy and Physiology: Nervous Tissues Laboratory Manual for Anatomy and Physiology :Nervous Tissue Lab; Timeline 80-120 min; (In the unit folder) Students will be able to: a) Identify the structure of the nervous system. b) Identify the structure of the neuron c)Classify neurons according to their structure d) classify the neurons according to their function Students will identify different microscopic slides and determine the part of the neuron the cells. Lab 17- Laboratory Manual for Anatomy and Physiology :Spinal Cord Structure and Function Students will able to: Laboratory Manual for Anatomy and Physiology :Spinal Cord Structure and Function -Lab; Timeline 200-250 min; (in the unit folder) Laboratory Manual for Anatomy and Physiology :Spinal Nerve -Lab; Timeline 200-250 min; (in the unit folder) Laboratory Manual for Anatomy and Physiology :Spinal Nerves-Lab; Timeline 200-250 min; (in the unit folder) Laboratory Manual for Anatomy and Physiology :Somatic Reflexes Lab; Timeline 200-250 min; (in the unit folder) a) Identify the protective structures of the spinal Meninges. 25 Anatomy & Physiology SI-H-A6 Communicating and defending a scientific argument; SIH-B1 Communicating that scientists usually base their investigations on existing models; SI-H-B2 Communicating that scientists conduct investigations for a variety of reasons, such as exploration of new areas, discovery if new aspects of the natural world, confirmation of prior investigations, evaluation of current theories, and comparison of models and theories; and SI-H-B3 Communicating that scientists rely on technology to enhance the gathering and manipulation of ideas. LS-H-A3 Investigating cell differentiation and describing stages of embryonic development of representative organisms. (HS-LS1-2), (HS-LS1-3) b) Describe the external features of the spinal cord. c) Identify the parts of the transverse section of the spinal cord. Interactive Anatomy -Illustrated Anatomy -Cadaver Practical Lab 18- Laboratory Manual for Anatomy and Physiology: Spinal Nerves. Students will be able to a)identify the connective tissue covering the spinal cord b) identify the rami of the spinal cord c)Identify the four spinal plexuses d) Identify major nerves from cervical brain to brachial plexuses Interactive Anatomy -Illustrated Anatomy -Cadaver Practical Lab 19- Laboratory Manual for Anatomy and Physiology: Somatic Reflexes 26 Anatomy & Physiology Students will be able to: a) identify the reflex arc b) Test a reflex Interactive Anatomy -Illustrated Anatomy -Cadaver Practical Part B- Storyline: (Brain) Cerebrovascular accident or stroke is the third leading cause of death in U.S. As member of the community improvement team for the city collaboration with St Joseph’s Hospital) you are assigned to write a report about the risk factors, preventions and treatments of strokes. Overarching Question: What makes the human brain so unique compare to the other species? Concepts Formative Assessment The brain registers sensations, correlate them with one another, stores information, make decisions, and take actions. Students who understand the concepts are able to: Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms. Communicate scientific and technical information about why the molecular-level structure is important in the functioning of designed materials. Conduct experiments, collect evidence, and analyze empirical data. Use evidence from experiments and other scientific reasoning to support oral and written explanations of how homeostasis influences the function of the human body. The brain contributes to homeostasis and also is the center for intelligence, emotions, behavior, and memory. The brain consist of four major parts; brain stem, cerebellum, diencephalon, and cerebrum. Learning Objective and Essential Questions Identify and describe possible causes and effects of positive and negative feedback in organisms Sample Activities Resources 27 Anatomy & Physiology Standard Determine the major external and internal structures of the brain. What is the main role of the brain? Describe how the brain is protected and how the blood supply is provided. How does the brain stores information Explain the formation and circulation of cerebrospinal fluid. Analyze the structure and function of the brain stem and reticular formation. Identify 12 pairs of cranial nerves. Determine the function of the 12 pairs of cranial nerves. Compare the structural and functional differences between the somatic and automatic parts of the nervous system. SI-H-A6 Communicating and defending a scientific argument; SI-H-B1 Communicating that scientists usually base their investigations on existing models; SI-H-B2 Communicating that scientists conduct investigations for a variety of reasons, such as exploration of new areas, discovery if new aspects of the natural world, Lab 20- Laboratory Manual for Anatomy and Physiology :The Brain Structure and Function Students will be able to: How do cranial nerves function? a) identify and label major parts of the brain What is the main role of cranial nerves? b) Determine the function of each part of the brain What is the correlation between cranial nerves structure and their function? c) Compare and contrast the sheep brain and human brain Students will have an interactive anatomy review Laboratory Manual for Anatomy and Physiology :The Brain Structure- Lab; Timeline 200-250 min; (in the unit folder) Laboratory Manual for Anatomy and Physiology :Contraction of the Cranial Nerves-Lab ; Timeline 200-250 min; (in the unit folder) Laboratory Manual for Anatomy and Physiology :Autonomic Nervous System Structure and Function -Lab ; Timeline 200-250 min; (in the unit folder) Illustrated Anatomy Cadaver Practice Lab 21- Laboratory Manual for Anatomy and Physiology: Cranial Nerves . Students will be able to a) Determine the location of the cranial nerves b) Identify the function of the cranial nerves Students will have an interactive anatomy review Illustrated Anatomy 28 Anatomy & Physiology confirmation of prior investigations, evaluation of current theories, and comparison of models and theories; and SI-H-B3 Communicating that scientists rely on technology to enhance the gathering and manipulation of ideas. LS-H-A3 Investigating cell differentiation and describing stages of embryonic development of representative organisms. (HS-LS1-2), (HS-LS1-3) Cadaver Practice Lab 22- Laboratory Manual for Anatomy and Physiology: Autonomic Nervous System Structure and Function. Students will be able to: a) Identify the structure of the Autonomic nervous system b) Describe the function of the Autonomic nervous system Students will have an interactive anatomy review through 3) Illustrated Anatomy 4) Cadaver Practical Part C- Storyline: (Senses) Many cancer patients may develop taste aversion due to the combination of drug and radiation treatment. As a new physician assistant working with cancer patients you are assigned to provide a treatment for the patients that have lost their taste so they can start to restore the taste Overarching Question: How do the sensory organs contribute to homeostasis? Concepts Formative Assessment Sensory organs have special receptors that allow us to smell, taste, see, hear, and maintain equilibrium. The information conveyed from these receptors to the central nervous system is used to help maintain homeostasis Students who understand the concepts are able to: Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms. Communicate scientific and technical information about why the molecular-level structure is important in the functioning of designed materials. 29 Anatomy & Physiology Learning Objective and Standard Describe the pathway from the sensory receptor to the cerebral cortex. Identify the areas of the body that have the greatest tactical discrimination. Analyze the adaptation of the sensory receptors. Analyze the phenomenon of referred pain. The Eye and Vision Perform visual tests that are used to determine distance visual acuity, near point, and astigmatism. Identify the accessory structures of the eye and the structure of the eyeball. The Ear, Hearing and Equilibrium Determine the structure of the Essential Questions Conduct experiments, collect evidence, and analyze empirical data. Use evidence from experiments and other scientific reasoning to support oral and written explanations of how homeostasis influences the function of the human body. Identify and describe possible causes and effects of positive and negative feedback in organisms Sample Activities How do senses work? Lab 23-General Senses: What is Pain? Students will be able to describe the pathway of the sensory receptors. How is information received by the sensory receptors? What are senses? What is the adaptation time? Identify the sensory receptors, sensory pathways and determine the adaptation of different sensory receptors. Interactive anatomy review Lab 24 -Special Senses-Eye Students will be able to: Identify the major structures of the eye Resources General Senses -Lab; timeline 120-180 min; (find the Lab packet in the unit folder) Special Senses: Eye Exam-Lab; timeline 120-180 min; (find the Lab packet in the unit folder) Special Senses: Hearing Exam-Lab; timeline 120-180 min; (find the Lab packet in the unit folder) Special Senses: Taste Exam-Lab; timeline 120-180 min; (find the Lab packet in the unit folder) Students will perform eye tests such as near vision, near point vision color blindness, astigmatism and myopia Lab 24 -Special Senses: Hearing 30 Anatomy & Physiology external, middle, and internal ear. Perform tests that exhibit the function of the receptors by dynamic and static equilibrium. The Nose and Olfaction Identify the location of receptors for olfaction. Determine the time adaptation for olfactory receptors. The Teste Buds and Gustation Identify the location of the receptors for taste Analyze the receptor structures that are responsible for taste Determine the influence of smell and texture on taste. Students will be able to: a) Identify major Anatomical parts of the ear b) perform Auditory and Equilibrium tests Lab 24 -Special Senses-Nose and Olfaction Students will be able to: a) determine olfactory structures b) identify taste buds c) Perform a taste test SI-H-A6 Communicating and defending a scientific argument; SI-H-B1 Communicating that scientists usually base their investigations on existing models; SI-H-B2 Communicating that scientists conduct investigations for a variety of reasons, such as exploration of new areas, discovery if new aspects of the natural world, confirmation of prior investigations, evaluation of current theories, and 31 Anatomy & Physiology comparison of models and theories; and SI-H-B3 Communicating that scientists rely on technology to enhance the gathering and manipulation of ideas. LS-H-A3 Investigating cell differentiation and describing stages of embryonic development of representative organisms. (HS-LS1-2), (HS-LS1-3) Unit Project/Lab Performance/Assessments Student physician diagnosis with written report and presentation Vocabulary Cranial nerve Gustation polysynaptic reflex Taste buds Equilibrium Spinal Meninges Olfactory structures Spinal cord Neurons Sensory receptors Rami Myopia Connective tissue Astigmatism monosynaptic reflex What It Looks Like in the Classroom 32 Anatomy & Physiology Instruction should result in students being able to use arguments based on empirical evidence and scientific reasoning to support an explanation of how characteristic of life and specialized structures affect the probability of successful evolution of human species. Students may observe, draw photographs, and microphotographs can be used by students to label parts of the human body in the laboratory. Possible activities could include Illustrated anatomy and Cadaver practical. Using the microscopes to view different tissue cells and compare and contrast cells of different tissues according to their specialization. Students will be use as physiological subjects to identify and role play different diagnosis correlated to the human anatomy. After the physiology experiment the students are asked to make predictions, collect data, analyze data, and write lab reports. Unlabeled four-color drawings are used by students to write the name of the structures and to help them memorize it. Then the completed diagrams are used to identify structures on models. Introduction of the phonetic pronunciation will encourage students to practice pronunciation; the discussion questions are placed with the purpose to make the students think about the material that is being presented. At this point students can have a deeper understanding of the subject matter; they are able to compare and contrast different structures of the human body; Identify models and structures on different models and manuals; and identify different photomicrograph, and different tissues under the microscope. Instruction that results in students being able to construct an evidence-based scientific explanation for how human body works and function will unable students to analyze and Identify the crucial role of individuals that work in the allied health fields. Prior Learning Life Science • Cell structure and function • Reproduction is essential to every kind of organism. • Organisms have both internal and macroscopic structures that allow for growth, survival, behavior, and reproduction. • Cells are specialized and grouped according to their function. Medical Terminology Use of medical terms is essential to Anatomy and Physiology students • • Future Learning Systems of specialized cells within organisms help perform essential functions of life. Human body is made of specialized tissues that have specific function 33 Anatomy & Physiology • Feedback mechanisms maintain an organism’s internal condition within certain limits and mediate behaviors. • Knowledge of the connection between structure and function is important to diagnose diseases and provide care Connections to Other Courses Allied health field such as: nursing, physical, respiratory, cardiovascular, or occupational therapy; radiology; and dental hygiene. Medical Field Clinical Discussions make the study of anatomy and Physiology relevant to students. Knowledge of the anatomy and physiology allows the students to understand and make connections between normal structures and abnormal ones. Similarly studying and reviewing literature will allow the find the identity, analyze, interpret and draw conclusions. Students will be provided with a rich background to be successful not only in the allied health careers but medical field as well. Appendix A: NGSS and Foundations for the Unit Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms. [Clarification Statement: Emphasis is on functions at the organism system level such as nutrient uptake, water delivery, and organism movement in response to neural stimuli. An example of an interacting system could be an artery depending on the proper function of elastic tissue and smooth muscle to regulate and deliver the proper amount of blood within the circulatory system.] [Assessment Boundary: Assessment does not include interactions and functions at the molecular or chemical reaction level.] (HS-LS1-2) Plan and conduct an investigation to provide evidence that feedback mechanisms maintain homeostasis. [Clarification Statement: Examples of investigations could include heart rate response to exercise, stomata response to moisture and temperature, and root development in response to water levels.] [Assessment Boundary: Assessment does not include the cellular processes involved in the feedback mechanism.] (HS-LS1-3) Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells. [Assessment Boundary: Assessment does not include identification of specific cell or tissue types, whole body systems, specific protein structures and functions, or the biochemistry of protein synthesis.] (HS-LS1-1) Crosscutting Concepts Science and Engineering Practices Disciplinary Core Ideas Developing and Using Models LS1.A: Structure and Function Systems and System Models Modeling in 9–12 builds on K–8 experiences and Multicellular organisms have a Models (e.g., physical, mathematical, progresses to using, synthesizing, and hierarchical structural organization, in computer models) can be used to simulate 34 Anatomy & Physiology developing models to predict and show relationships among variables between systems and their components in the natural and designed worlds. Develop and use a model based on evidence to illustrate the relationships between systems or between components of a system. (HS-LS1-2) Planning and Carrying Out Investigations Planning and carrying out in 9-12 builds on K-8 experiences and progresses to include investigations that provide evidence for and test conceptual, mathematical, physical, and empirical models. Plan and conduct an investigation individually and collaboratively to produce data to serve as the basis for evidence, and in the design: decide on types, how much, and accuracy of data needed to produce reliable measurements and consider limitations on the precision of the data (e.g., number of trials, cost, risk, time), and refine the design accordingly. (HS-LS1-3) which any one system is made up of numerous parts and is itself a component of the next level. (HS-LS1-2) Feedback mechanisms maintain a living system’s internal conditions within certain limits and mediate behaviors, allowing it to remain alive and functional even as external conditions change within some range. Feedback mechanisms can encourage (through positive feedback) or discourage (negative feedback) what is going on inside the living system. (HS-LS1-3) Systems of specialized cells within organisms help them perform the essential functions of life. All cells contain genetic information in the form of DNA molecules. Genes are regions in the DNA that contain the instructions that code for the formation of proteins, which carry out most of the work of cells. (Note: This Disciplinary Core Idea is also addressed by HS-LS3-1.) (HS-LS1-1) systems and interactions—including energy, matter, and information flows—within and between systems at different scales. (HS-LS1-2) Stability and Change Feedback (negative or positive) can stabilize or destabilize a system. (HS-LS1-3) Structure and Function Investigating or designing new systems or structures requires a detailed examination of the properties of different materials, the structures of different components, and connections of components to reveal its function and/or solve a problem. (HS-LS1-1) Constructing Explanations and Designing Solutions Constructing explanations and designing solutions in 9–12 builds on K–8 experiences and progresses to explanations and designs that are supported by multiple and independent student-generated sources of evidence 35 Anatomy & Physiology consistent with scientific ideas, principles, and theories. Construct an explanation based on valid and reliable evidence obtained from a variety of sources (including students’ own investigations, models, theories, simulations, peer review) and the assumption that theories and laws that describe the natural world operate today as they did in the past and will continue to do so in the future. (HSLS1-1) ________________________________________ Connections to Nature of Science Scientific Investigations Use a Variety of Methods Scientific inquiry is characterized by a common set of values that include: logical thinking, precision, open-mindedness, objectivity, skepticism, replicability of results, and honest and ethical reporting of findings. (HS-LS1-3) English Language Arts SL.11-12.5 Make strategic use of digital media (e.g., textual, graphical, audio, visual, and interactive elements) in presentations to enhance understanding of findings, reasoning, and evidence and to add interest. (HS-LS1-2) WHST.9-12.7 Conduct short as well as more sustained research projects to answer a question (including a self-generated question) or solve a problem; narrow or broaden the inquiry when appropriate; synthesize multiple sources on the subject, demonstrating understanding of the subject under investigation. (HS-LS1-3) WHST.11-12.8 Gather relevant information from multiple authoritative print and digital sources, using advanced searches effectively; assess the 36 Anatomy & Physiology strengths and limitations of each source in terms of the specific task, purpose, and audience; integrate information into the text selectively to maintain the flow of ideas, avoiding plagiarism and overreliance on any one source and following a standard format for citation. (HS-LS1-3) RST.11-12.1 Cite specific textual evidence to support analysis of science and technical texts, attending to important distinctions the author makes and to any gaps or inconsistencies in the account. (HS-LS1-1) WHST.9-12.2 Write informative/explanatory texts, including the narration of historical events, scientific procedures/ experiments, or technical processes. (HS-LS1-1) WHST.9-12.9 Draw evidence from informational texts to support analysis, reflection, and research. (HS-LS1-1) Suggested Field Trips Liberty Science Center, St. Joseph’s Hospital 37
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