Episode Two Debriefing: Teacher Guide ACTIVITY 1 TRUTH AND CONSEQUENCES Why do some people get high from a couple of drinks while others need more alcohol to become intoxicated? In this activity, students will learn how differences in body type affect reaction to alcohol. Background Alcohol is a drug that can affect a person’s ability to perform. However, how quickly performance is affected depends on many factors, including a person’s size and body composition. The Path of Alcohol After alcohol is ingested, it travels from the esophagus to the stomach. In the stomach, a little alcohol may enter the bloodstream (20%), but most of it moves to the small intestines. In the small intestines, most of the alcohol is absorbed into the body’s bloodstream (80%), and from there it is carried to the heart, the brain, and the liver. In the liver, alcohol is converted to energy. However, the liver can only process about half an ounce of alcohol an hour, which means that the rest of the alcohol continues to affect the other parts of the body, such as the brain. The brain is where alcohol causes the familiar effects associated with alcohol consumption, including physiologic sedation, relaxation, memory gaps, delirium, slower reaction time, and confusion. Alcohol Concentration and the Body A person’s body type can influence the effect that alcohol produces. When alcohol is consumed, it is distributed throughout the water-containing parts of the body. In the liver, alcohol is metabolized into acetaldehyde and then into water and carbon dioxide. The carbon dioxide is excreted from the body. However, the liver can only work so fast. Intoxication occurs when the amount of alcohol consumed is greater than the amount of alcohol broken down. Furthermore, alcohol is miscible (mixable) in water but not in fat. A person with more body fat has less body water and thus a higher concentration of alcohol in their body when they drink. The amount of body fat is influenced by gender, weight, and body type. For instance, women have more body fat than men and as a consequence are more greatly affected by alcohol. Additionally, body type also includes the genetic makeup of a person. Alcohol dehydrogenase is the enzyme involved in metabolizing alcohol. The presence of a normal enzyme is genetically defined. If a person has a mutated form of this enzyme, alcohol is not metabolized correctly, causing a rise in the breakdown products of alcohol. This activity was adapted from Understanding Alcohol: Investigations into Biology and Behavior from the National Institute on Alcohol Abuse and Alcoholism. The Reconstructors® 9 Nothing To Rave About: Episode 2 Episode Two Debriefing: Teacher Guide Learning Objectives The student will: 1. describe which parts of the body are affected when alcohol is ingested. 2. learn about the miscibility of alcohol. 3. compare the dilution of alcohol in water and in oil. 4. participate in a demonstration of how body size and type influence the concentration of alcohol in the body. 5. test their ability to perform under the influence of alcohol. Materials 1. 2. 3. 4. 5. 6. 7. 8. 9. Truth and Consequence Student Activity Sheet two clear drinking glasses (per group) that hold at least 8 oz. of liquid spoons two containers (per group) that hold at least 2 oz. of liquid two ounces of isopropyl alcohol (per group) water mineral oil red food coloring computer with Internet access Procedure Part One In this activity, students will learn about the miscibility of alcohol in water and how this can alter the effect of the drug on the body. 1. Before class, set up the different body models and the alcohol sample for each group. A. The body models differ by the amount of oil (fat) in each glass. Fill the clear drinking glasses as follows: oil water B. The alcohol sample is red food coloring added to an ounce of isopropyl alcohol (The students need one ounce per body model). 2. At the beginning of class, introduce the topic of alcohol and how it affects a person. Specifically, discuss how alcohol is distributed in the body by the bloodstream. 3. Use the picture of the body to trace the path that alcohol takes upon ingestion. 4. Tell the students that they are going to use a model of two different body types to visualize the distribution of alcohol in the body. 5. Distribute a set of body type models to each group. Tell the students what each layer is, and ask the class to guess what they think each layer represents in the body. A. Oil = fat B. Water = water The Reconstructors® 10 Nothing To Rave About: Episode 2 Episode Two Debriefing: Teacher Guide 6. Distribute the alcohol samples to each group. The alcohol represents a drink. Ask the students to hypothesize what they think will happen when alcohol is added to each body type. 7. Each group can write its hypothesis down on the Truth and Consequences Student Activity Sheet. 8. Have each group add one sample of alcohol (one ounce) to each model and gently stir the mixture. 9. Wait a few minutes, and then look at the models and see if the hypothesis was correct. Were there any surprises? 10. Students should record their observations on their Truth and Consequences Student Activity Sheet. 11. As a class, answer the discussion questions. Part 2 This activity requires Internet access. The students will research the effects of alcohol on the different organs of the body, and they can play a game that simulates the effects of alcohol on the brain. 1. Before performing Part 2 of Truth and Consequences, make copies of the image of the human body. 2. Discuss with the class the path that alcohol takes once ingested (if you have not already done so in Part One). 3. Ask the students to use the Internet to research the different organs of the body and how they are negatively affected by alcohol. The suggested web sites are listed on page 14. 4. As a class, discuss what the students find. 5. Elaborate on how alcohol affects the brain and how this can affect a person’s ability to operate a vehicle. 6. Students are also invited to play a game that simulates what it would be like to drive under the influence of alcohol. Game: LifeBytes: Drinking and Driving (works best on a PC) http://www.lifebytes.gov.uk/alcohol/ alc_menu.html The Reconstructors® 11 Nothing To Rave About: Episode 2 Episode Two Debriefing: Teacher Guide Truth and Consequences In the first part of this activity, you will use models of the human body to see how alcohol is distributed in the body. 1. Hypothesis: Where do you think the alcohol will end up after the drink is added to the models of the human body? The alcohol should move into the water layer in both models. Bubbles may appear in the oil layer, but the majority should be in the water layer. 2. Observations: What happened to the alcohol when you added it to the different models? The alcohol mixed with all of the layers, but it moved to the water layer. Alcohol is not miscible in oil. The oil levels stayed the same in both models, and all of the alcohol was mixed into the water layers (with a few bubbles in the oil). 3. Was your hypothesis correct or incorrect and why? Discussion Questions 1. Which model had a higher concentration of alcohol? The one with more oil or more water? The one with more oil had a higher concentration of alcohol. This is why a person with more body fat is affected by alcohol to a greater extent. The other model had more water to mix with the alcohol, thereby diluting the alcohol. 2. Can you tell how alcohol will affect a person based solely on their body type? No. Two people that are the same size may have different amounts of body fat. Body fat content cannot be determined by appearance alone. It is not possible to predict the effects of alcohol on an individual solely by looking at them. 3. If two individuals have the same amount of body fat but one individual is larger than the other, who would be more affected by drinking alcohol? In general, a larger person will be less influenced by a given alcohol dose than a smaller person because a larger body size means a greater blood volume for alcohol distribution. However, other factors, such as genetic makeup, can influence the effect of alcohol. 4. Since the brain is sensitive to the effects of alcohol, what can you conclude about the composition of the brain? Remember that alcohol is distributed in water-containing organs, which leads us to believe that the brain contains a significant amount of water. The Reconstructors® 12 Nothing To Rave About: Episode 2 Episode Two Debriefing: Teacher Guide The Effects of Alcohol on the Body Brain Alcohol is a depressant and can inhibit certain functions of the brain. For instance, alcohol can cause respiratory depression by inhibiting the nerves that control breathing. This can be fatal. Teacher Version Sample Answers Heart Although scientists have found that moderate amounts of alcohol can benefit the heart, heavy drinking of alcohol can increase blood pressure, which can lead to a heart attack or stroke. Esophagus and Stomach When alcohol is ingested it can irritate the esophagus. In the stomach, alcohol increases the amount of digestive juices, which can damage the stomach lining. Liver Alcohol prevents the breakdown of fats in the liver. The fats accumulate in liver cells and can rupture or grow into cysts. The cysts replace normal cells and can lead to fibrous scar tissue or cirrhosis of the liver. The Reconstructors® Kidney Alcohol can damage the kidneys and lead to kidney swelling and a significant reduction in kidney function. Small Intestines Alcohol can damage the small intestines and decrease nutrient absorption. Additionally, damage to the muscles of the intestinal wall can occur, causing severe diarrhea. 13 Nothing To Rave About: Episode 2 Episode Two Debriefing: Teacher Guide Extension Activities • • • Mathematics: Calculate the blood alcohol level of a person with 5% body fat, 10% body fat, and 15% body fat. Visual Arts: Make a model of the route that alcohol takes once it is ingested. History: Research the medical use of alcohol. Standards National Science Education Standards, Grades 5-8 • • • Science Content Standard A: All students should develop abilities necessary to do scientific inquiry. Science Content Standard F: All students should develop understanding of personal health. Science Content Standard F: All students should develop understanding of risks and benefits. Books • Margaret O. Hyde, 1999. Alcohol 101: An Overview for Teens. Brookfield, Conn.: Twenty-First Century Books. Web Sites • Lifebytes http://www.lifebytes.gov.uk/alcohol/alc_menu.html • National Institute on Alcohol Abuse and Alcoholism http://www.niaaa.nih.gov/ • The Cool Spot http://www.thecoolspot.gov/ • Substance Abuse and Mental Health Services Administration http://getfit.samhsa.gov/Alcohol/ The Reconstructors® 14 Nothing To Rave About: Episode 2 Episode Two Debriefing: Teacher Guide TRUTH AND CONSEQUENCES The truth is that your body type can affect your reaction to alcohol. In this activity, learn how alcohol gets distributed in the body and why the brain can be greatly affected by this drug. Materials 1. 2. 3. 4. 5. Truth and Consequences Student Activity Sheet two different body type models (glasses containing oil and water) spoons two sample drinks computer with Internet access Procedure Part I 1. Separate into groups. 2. Each group will need a set of body type models. What do you think the layers represent? 3. Next, each group should obtain two samples of alcohol. DO NOT DRINK the alcohol sample. It is rubbing alcohol. It only represents a drink of alcohol. 4. Formulate a hypothesis. You are going to add one “drink” of alcohol to each body type model. This will simulate the effect that drinking alcohol has on the body. Before you add the alcohol, generate a hypothesis on how you think the alcohol will be distributed in each model. Will the alcohol rise to the top, stay in the middle, or sink to the bottom? Write your hypothesis on the Truth and Consequences Student Activity Sheet. 5. Add one sample of alcohol to each glass and gently stir the mixture. 6. Wait a few minutes, and then look at the models. Write your group’s observations on what happened to the alcohol in the Truth and Consequences Student Activity Sheet. 7. Was your hypothesis was correct? Why do you think your hypothesis was correct or incorrect? 8. Answer the discussion questions and discuss them with class. The Reconstructors® 15 Nothing To Rave About: Episode 2 Episode Two Debriefing: Teacher Guide Part II 1. Use the Internet to research the different organs of the body listed in the Truth and Consequences Student Activity Sheet. Find out how these organs are negatively affected by the use of alcohol. 2. Participate with the class in a discussion of what you found. 3. After you have discussed the effects of alcohol on the body and brain, you can play a game that simulates what it would be like to drive under the influence of alcohol. Suggested Web Sites: • Substance Abuse and Mental Health Services Administration http://getfit.samhsa.gov/Alcohol/ • National Institute on Alcohol Abuse and Alcoholism (NIAAA) http://www.niaaa.nih.gov/ Game: • LifeBytes: Drinking and Driving (works best on a PC) http://www.lifebytes.gov.uk/alcohol/alc_menu.html The Reconstructors® 16 Nothing To Rave About: Episode 2 Episode Two Debriefing: Teacher Guide Name: ______________________________ Class: __________ Date Truth and Consequences In the first part of this activity, you will use models of the human body to see how alcohol gets distributed in the body. 1. Hypothesis: Where do you think the alcohol will end up after it is added to the models of the human body? 2. Observations: What happened to the alcohol when you added it to the different models? 3. Was your hypothesis correct or incorrect and why? Discussion Questions 1. Which model had a higher concentration of alcohol? The one with more oil or more water? 2. Can you tell how alcohol will affect a person based solely on their body type? 3. If two individuals have the same amount of body fat but one individual is larger than the other, who would be more affected by drinking beer? 4. Since the brain is sensitive to the effects of alcohol, what can you conclude about the composition of the brain? The Reconstructors® 17 Nothing To Rave About: Episode 2 Episode Two Debriefing: Teacher Guide Name: ______________________________ Class: __________ Date Truth and Consequences The effects of alcohol on the body Brain Heart Esophagus and Stomach Kidney Liver Small Intestines The Reconstructors® 18 Nothing To Rave About: Episode 2
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