GBD PROFILE: LITHUANIA GLOBAL BURDEN OF DISEASES, INJURIES, AND RISK FACTORS STUDY 2010 The Global Burden of Disease Study 2010 (GBD 2010) is a collaborative project of nearly 500 researchers in 50 countries led by the Institute for Health Metrics and Evaluation (IHME) at the University of Washington. It is the largest systematic scientific effort in history to quantify levels and trends of health loss due to diseases, injuries, and risk factors. GBD serves as a global public good to inform evidence-based policymaking and health systems design. PROFILE OVERVIEW 15 + −7 9 80 −7 4 75 −6 9 70 −6 4 65 −5 9 60 −5 4 55 −4 9 50 −4 4 45 −3 9 40 −3 4 35 −2 9 30 −2 4 25 −1 9 20 15 9 0 −1 4 ● This chart shows the decline in mortality rate at every age range. The higher points on the chart indicate that declines in mortality rates were faster in those age groups between 1990 and 2010. The greatest reductions in all-cause mortality rate were experienced by males aged <1 year (62%). Males aged 55-59 years saw the smallest decrease in mortality rate (0%). 30 10 ● 45 4 ALL-CAUSE MORTALITY RATE 60 5− ● Percent decline in age-specific mortality rate by sex from 1990-2010 in Lithuania 1− ● In terms of the number of years of life lost (YLLs) due to premature death in Lithuania, ischemic heart disease, cerebrovascular disease, and self-harm were the highest ranking causes in 2010. Of the 25 most important causes of burden, as measured by disability-adjusted life years (DALYs), road injury showed the largest decrease, falling by 44% from 1990 to 2010. The leading risk factor in Lithuania is dietary risks. Percent decline in age−specific mortality rate ● Age group Males Females CAUSES OF PREMATURE DEATH Years of life lost (YLLs) quantify premature mortality by weighting younger deaths more than older deaths. Ranks for top 25 causes of YLLs 1990-2010, Lithuania # YLLs in thousands (% of total) Rank and disorder 1990 227 (25.9%) 1 Ischemic heart disease 76 (8.6%) 2 Stroke 49 (5.6%) 3 Road injury 52 (5.9%) 4 Self-harm 35 (4.0%) 5 Lung cancer 28 (3.2%) 6 Congenital anomalies 25 (2.8%) 7 Stomach cancer 25 (2.9%) 8 Alcohol use disorders 23 (2.6%) 9 Drowning 23 (2.6%) 10 COPD 14 (1.6%) 11 Falls 14 (1.6%) 12 Colorectal cancer 14 (1.6%) 13 Interpersonal violence 14 (1.5%) 14 Breast cancer 12 (1.4%) 15 Lower respiratory infections 11 (1.3%) 16 Cardiomyopathy 11 (1.3%) 17 Cirrhosis 10 (1.2%) 18 Preterm birth complications 10 (1.1%) 19 Rheumatic heart disease 9 (1.0%) 20 Tuberculosis 9 (1.0%) 21 Mechanical forces 9 (1.0%) 22 Poisonings 8 (1.0%) 23 Pancreatic cancer 8 (1.0%) 24 Leukemia 7 (0.8%) 25 Neonatal encephalopathy 27 Ovarian cancer 28 Brain cancer 31 Hypertensive heart disease 32 Kidney cancers 38 Other cardio & circulatory http://www.healthmetricsandevaluation.org Rank and disorder 2010 1 Ischemic heart disease 2 Stroke 3 Self-harm 4 Lung cancer 5 Cirrhosis 6 Road injury 7 Alcohol use disorders 8 Cardiomyopathy 9 Colorectal cancer 10 Drowning 11 Falls 12 Stomach cancer 13 Interpersonal violence 14 Lower respiratory infections 15 Breast cancer 16 COPD 17 Pancreatic cancer 18 Other cardio & circulatory 19 Tuberculosis 20 Congenital anomalies 21 Kidney cancers 22 Hypertensive heart disease 23 Brain cancer 24 Leukemia 25 Ovarian cancer 27 Poisonings 40 Mechanical forces 42 Rheumatic heart disease 43 Preterm birth complications 53 Neonatal encephalopathy # YLLs in thousands (% of total) % change 195 (25.9%) -15 71 (9.5%) -2 48 (6.4%) -6 28 (3.7%) -24 28 (3.7%) 218 25 (3.4%) -51 22 (2.9%) -32 18 (2.3%) 65 17 (2.2%) 16 14 (1.9%) -40 14 (1.8%) -4 14 (1.8%) -43 14 (1.8%) -2 13 (1.7%) 25 12 (1.6%) -13 12 (1.6%) -49 9 (1.2%) 10 8 (1.1%) 136 8 (1.1%) -7 7 (0.9%) -76 7 (0.9%) 49 6 (0.8%) 49 6 (0.8%) 27 6 (0.8%) -26 6 (0.8%) -1 This chart shows the change in the top 25 causes of YLLs due to premature mortality from 1990 to 2010. Solid lines indicate a cause has moved up in rank or stayed the same. Broken lines indicate a cause has moved down in rank. The causes are color coded by blue for non-communicable diseases, green for injuries, and red for communicable, maternal, neonatal, and nutritional causes of death. Lithuania | GBD | page 1 YEARS LIVED WITH DISABILITY (YLDs) Years lived with disability (YLDs) are estimated by weighting the prevalence of different conditions based on severity. The top five leading causes of YLDs in Lithuania are low back pain, major depressive disorder, other musculoskeletal disorders, neck pain, and diabetes mellitus. Lithuania YLDs by cause and age 2010 40,000 War & disaster Intentional injuries Unintentional injuries Transport injuries 30,000 Other non−communicable Musculoskeletal disorders Diabetes/urogen/blood/endo Mental & behavioral disorders Neurological disorders YLDs The size of the colored portion in each bar represents the number of YLDs attributable to each cause. The height of each bar shows which age groups had the most YLDs in 2010. The causes are aggregated. For example, musculoskeletal disorders include low back pain and neck pain. Digestive diseases Cirrhosis 20,000 Chronic respiratory diseases Cardio & circulatory diseases Cancer Other communicable Nutritional deficiencies Neonatal disorders 10,000 Maternal disorders NTD & malaria Diarrhea/LRI/other infectious HIV/AIDS & tuberculosis 0− 6 7− da 28 27 ys −3 da 64 ys 1− da 4 ys 5− yea 10 9 y rs −1 ea 15 4 y rs −1 ea 20 9 y rs −2 ea 25 4 y rs −2 ea 30 9 y rs −3 ea 35 4 y rs −3 ea 40 9 y rs −4 ea 45 4 y rs −4 ea 50 9 y rs −5 ea 55 4 y rs −5 ea 60 9 y rs −6 ea 65 4 y rs −6 ea 70 9 y rs −7 ea 75 4 y rs −7 ea 9 rs 80 yea + rs ye ar s 0 DISABILITY-ADJUSTED LIFE YEARS (DALYs) Disability-adjusted life years (DALYs) quantify both premature mortality (YLLs) and disability (YLDs) within a population. In Lithuania, the top three causes of DALYs in 2010 were ischemic heart disease, cerebrovascular disease, and low back pain. Two causes that appeared in the 10 leading causes of DALYs in 2010 and not 1990 were cirrhosis of the liver and falls. CC Non-communicable 17 19 OTHER CARDIO & CIRCULATORY 22 21 24 25 BREAST CANCER 20 18 16 LOWER RESPIRATORY INFECTIONS DRUG USE DISORDERS COLORECTAL CANCER 15 14 MIGRAINE 13 23 STOMACH CANCER COPD 12 OSTEOARTHRITIS DIABETES 11 DROWNING LUNG CANCER ROAD INJURY MAJOR DEPRESSIVE DISORDER ALCOHOL USE DISORDERS SELF-HARM STROKE ISCHEMIC HEART DISEASE -50 10 INTERPERSONAL VIOLENCE 9 8 CARDIOMYOPATHY 7 NECK PAIN 6 OTHER MUSCULOSKELETAL LOW BACK PAIN 5 FALLS CIRRHOSIS 150 50 100 4 3 -150 CC Communicable, maternal, neonatal, and nutritional 2 0 1 -100 Percent change 1990-2010 The top 25 causes of DALYs are ranked from left to right in order of the number of DALYs they contributed in 2010. Bars going up show the percent by which DALYs have increased since 1990. Bars going down show the percent by which DALYs have decreased. Globally, non-communicable diseases and injuries are generally on the rise, while communicable, maternal, neonatal, and nutritional causes of DALYs are generally on the decline. 200 Leading causes of DALYs and percent change 1990 to 2010 for Lithuania -200 CC Injuries http://www.healthmetricsandevaluation.org Lithuania | GBD | page 2 RISK FACTORS Overall, the three risk factors that account for the most disease burden in Lithuania are dietary risks, high blood pressure, and alcohol use. The leading risk factors for children under 5 and adults aged 15-49 years were iron deficiency and alcohol use, respectively, in 2010. Burden of disease attributable to 15 leading risk factors in 2010, expressed as a percentage of Lithuania DALYs Dietary risks High blood pressure War & disaster Alcohol use The graph shows the top 15 risk factors for Lithuania. The colored portion of each bar represents the specific diseases attributable to that risk factor while bar size represents the percentage of DALYs linked to specific risk factors. Intentional injuries Unintentional injuries High body−mass index Transport injuries Other non−communicable Smoking Musculoskeletal disorders Diabetes/urogen/blood/endo Physical inactivity Mental & behavioral disorders Neurological disorders High total cholesterol Digestive diseases High fasting plasma glucose Cirrhosis Chronic respiratory diseases Ambient PM pollution Cardio & circulatory diseases Cancer Occupational risks Other communicable Nutritional deficiencies Household air pollution Neonatal disorders Maternal disorders Drug use NTD & malaria Diarrhea/LRI/other infectious Iron deficiency HIV/AIDS & tuberculosis Intimate partner violence Lead 0 5 10 15 % DALYs attributable to risk factors 20 COUNTRY BENCHMARKING OF BURDEN OF DISEASE Understanding the relative performance of Lithuania against other comparator countries provides key insight into public health successes and areas where Lithuania might be falling behind. The table identifies Lithuania's rank across 14 other comparator countries, selected and ordered by income per capita, for five metrics of interest, with 1 indicating the best rank and 15 indicating the worst rank. ● Age-standardized rates are used to make meaningful comparisons across time by adjusting for changes in population size and age structure. ● Life expectancy incorporates mortality, and health-adjusted life expectancy further incorporates years lived in less than ideal health. ● In 2010, Lithuania ranked 7th for age-standardized YLD rate and 12th for age-standardized YLL rate. Country Age-standardized death rates, YLL rates, YLD rates, and life expectancy at birth and health-adjusted life expectancy at birth for 1990 and 2010, both sexes combined Age-standardized death rate Age-standardized YLL rate Age-standardized YLD rate Health-adjusted life Life expectancy at birth (per 100,000) (per 100,000) (per 100,000) expectancy at birth 1990 2010 1990 2010 1990 2010 1990 2010 1990 2010 Rate Rank Rate Rank Rate Rank Rate Rank Rate Rank Rate Rank LE Rank LE Rank HALE Rank HALE Slovakia 893 10 652 9 20,667 7 13,779 4 11,905 9 11,042 4 71 9 75.4 8 61.2 10 65.4 7 Hungary 970 14 694 11 23,806 13 15,271 8 11,665 7 11,589 10 69.4 13 74.5 10 60.2 13 64.2 10 Estonia 910 11 603 6 23,443 11 13,954 6 11,129 2 11,165 5 69.8 11 75.9 6 61 11 65.7 6 Antigua and Barbuda 728 2 593 4 19,168 2 13,919 5 12,425 13 13,535 14 73.1 1 76.5 3 62.7 4 63.3 12 Croatia 830 7 585 2 19,273 3 11,918 2 12,083 12 11,620 11 71.9 5 76.7 2 61.8 6 66 5 Libya 693 1 645 8 19,723 5 15,897 10 13,033 14 13,106 13 72.7 3 74.7 9 61.3 9 62.9 13 Poland 872 9 589 3 21,136 9 13,059 3 11,652 6 11,401 8 70.9 10 76.3 4 61.5 8 66.1 4 Lithuania 833 8 678 10 21,127 8 16,608 12 11,684 8 11,302 7 71.3 8 74.1 11 61.7 7 64.3 9 Latvia 914 12 703 12 23,599 12 16,613 13 11,911 10 11,751 12 69.8 12 73.9 12 60.4 12 63.8 11 Russia 953 13 952 14 25,715 14 25,387 14 11,536 5 11,444 9 68.7 14 68.9 14 59.7 14 59.9 14 Mexico 740 4 604 7 22,775 10 15,658 9 10,092 1 9,364 1 71.5 7 75.5 7 63 3 66.9 2 Chile 760 5 490 1 18,210 1 11,136 1 11,185 4 10,407 2 72.9 2 78.5 1 63.4 1 68.6 1 1,312 15 1,432 15 46,033 15 49,393 15 14,356 15 14,462 15 60 15 58.7 15 50.8 15 49.8 15 Gabon Rank Malaysia 825 6 726 13 19,850 6 16,000 11 11,926 11 11,186 6 71.6 6 73.7 13 62.1 5 64.4 8 Argentina 731 3 597 5 19,400 4 14,343 7 11,154 3 10,843 3 72.5 4 76 5 63.2 2 66.1 3 http://www.healthmetricsandevaluation.org Lithuania | GBD | page 3 COUNTRY BENCHMARKING OF BURDEN OF DISEASE, CONTINUED This figure shows the rank of Lithuania relative to the same comparator countries for the leading causes of DALYs in 1990 (top) and 2010 (bottom). ● The columns are ordered by the absolute number of DALYs in Lithuania for that particular year, with greatest burden on the left. ● The numbers indicate the rank across countries for each cause in terms of age-standardized DALY rates, with 1 as the best performance and 15 as the worst. Latvia Russia Mexico Chile Gabon Malaysia Preterm birth complications Rheumatic heart disease Lower respiratory infections Colorectal cancer Interpersonal violence Iron-deficiency anemia Other musculoskeletal Stomach cancer Congenital anomalies Alcohol use disorders Major depressive disorder Low back pain 7 3 13 4 14 9 6 3 6 8 3 3 14 8 10 15 13 2 6 1 11 9 14 13 2 15 10 5 12 15 8 8 13 4 13 7 13 10 12 9 3 2 9 5 13 15 11 14 12 3 6 14 11 9 4 6 9 12 3 3 7 8 10 1 10 3 12 2 10 6 14 12 4 1 6 1 12 1 3 2 10 6 10 9 5 5 6 4 7 14 6 15 4 7 6 3 12 6 9 8 2 8 12 12 10 1 4 14 4 8 9 5 14 9 8 8 14 1 8 15 3 1 10 9 11 4 14 15 9 5 13 1 7 2 7 1 4 1 5 13 11 6 5 2 4 2 9 1 10 11 5 3 13 15 11 14 11 11 9 12 15 3 13 13 14 10 11 15 11 7 9 15 13 10 4 8 9 10 11 11 12 11 12 14 15 9 12 9 8 1 4 8 7 9 12 8 10 13 11 1 4 9 10 6 5 13 15 1 5 11 1 15 1 12 5 9 1 13 3 12 2 11 6 12 7 11 3 13 7 4 1 15 4 12 10 8 11 11 3 2 15 10 11 14 15 13 1 7 2 9 14 7 5 7 14 12 3 8 10 2 4 2 9 3 15 4 6 9 5 4 13 8 2 5 15 5 2 6 14 6 9 14 3 1 11 14 10 15 13 5 12 1 14 10 11 5 4 5 3 13 15 1 4 2 8 5 8 7 15 12 7 6 2 1 3 7 10 2 13 Breast cancer 10 Drowning 7 14 12 Falls 13 15 7 Lung cancer 6 7 11 COPD 7 12 11 Self-harm 13 10 14 Road injury Osteoarthritis Poland Lithuania Migraine Croatia Libya Diabetes Estonia Antigua and Barbuda Neck pain Slovakia Hungary Stroke Country Ischemic heart disease Ranking of leading age-standardized rates of disability-adjusted life years (DALYs) relative to comparator countries in 1990 Alcohol use disorders Major depressive disorder Road injury Cirrhosis Lung cancer Falls COPD Diabetes Cardiomyopathy Neck pain Colorectal cancer Osteoarthritis Interpersonal violence Drug use disorders Drowning Lower respiratory infections Stomach cancer Other cardio & circulatory Migraine Breast cancer 13 15 6 13 7 6 3 2 5 4 10 13 11 15 13 15 6 13 4 10 3 9 5 10 12 9 14 15 11 13 6 2 1 2 3 2 9 1 7 10 10 9 15 13 8 14 8 3 5 4 7 3 10 1 13 10 11 12 2 1 4 3 8 1 7 5 1 2 5 14 10 8 12 4 10 3 7 6 7 9 9 7 15 14 10 8 3 7 11 2 5 14 11 8 7 6 6 11 8 12 12 8 8 2 4 1 13 15 9 14 8 2 13 4 12 4 8 12 8 15 5 1 6 7 8 1 13 2 10 15 1 4 6 7 1 5 2 10 9 3 6 15 12 3 10 5 7 13 10 7 14 11 11 15 11 15 4 6 10 12 7 12 14 9 14 11 9 4 7 2 4 7 8 14 11 5 11 8 12 4 3 12 5 12 6 15 4 6 8 12 7 8 14 9 9 12 Russia 14 15 13 15 10 9 12 14 12 14 9 10 7 13 5 11 10 12 9 8 3 11 6 3 6 11 15 13 7 6 9 12 6 5 10 14 9 13 12 13 5 12 13 15 4 1 10 7 11 13 Mexico Chile 2 1 1 2 1 5 4 9 5 9 1 5 11 3 14 9 2 5 1 3 7 5 13 1 12 14 1 2 4 14 1 4 14 2 15 8 4 8 9 4 11 8 5 14 2 3 5 1 1 2 Gabon Malaysia 5 9 14 11 6 2 7 3 2 3 14 8 15 8 15 1 3 6 10 6 15 14 12 11 13 2 11 3 13 2 3 5 8 1 13 5 11 3 14 11 15 14 4 1 13 11 4 6 4 3 Argentina 4 3 4 5 8 7 6 6 7 2 10 9 15 9 15 10 3 11 10 7 13 6 12 2 15 Hungary Estonia Antigua and Barbuda Croatia Libya Poland Lithuania Latvia Ranking Legend 1-3 Institute for Health Metrics and Evaluation 2301 Fifth Ave., Suite 600 Seattle, WA 98121 USA 4-7 8 - 11 Other musculoskeletal Self-harm 6 9 Slovakia Stroke 12 10 Country Ischemic heart disease Low back pain 6 6 4 2 4 8 3 14 6 2 7 2 8 2 2 10 13 1 6 4 5 4 2 5 6 5 5 8 7 8 3 5 3 15 14 7 12 8 7 15 Argentina Ranking of leading age-standardized rates of disability-adjusted life years (DALYs) relative to comparator countries in 2010 12 - 15 Telephone: +1-206-897-2800 E-mail: [email protected] www.healthmetricsandevaluation.org Lithuania | GBD | page 4
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