risk factors - Institute for Health Metrics and Evaluation

GBD PROFILE: LITHUANIA
GLOBAL BURDEN OF DISEASES, INJURIES, AND RISK FACTORS STUDY 2010
The Global Burden of Disease Study 2010 (GBD 2010) is a collaborative project of nearly 500 researchers in 50 countries led by the
Institute for Health Metrics and Evaluation (IHME) at the University of Washington. It is the largest systematic scientific effort in history to
quantify levels and trends of health loss due to diseases, injuries, and risk factors. GBD serves as a global public good to inform
evidence-based policymaking and health systems design.
PROFILE OVERVIEW
15
+
−7
9
80
−7
4
75
−6
9
70
−6
4
65
−5
9
60
−5
4
55
−4
9
50
−4
4
45
−3
9
40
−3
4
35
−2
9
30
−2
4
25
−1
9
20
15
9
0
−1
4
●
This chart shows the decline in mortality rate at every age range.
The higher points on the chart indicate that declines in mortality
rates were faster in those age groups between 1990 and 2010.
The greatest reductions in all-cause mortality rate were
experienced by males aged <1 year (62%). Males aged 55-59
years saw the smallest decrease in mortality rate (0%).
30
10
●
45
4
ALL-CAUSE MORTALITY RATE
60
5−
●
Percent decline in age-specific mortality rate by sex from 1990-2010 in Lithuania
1−
●
In terms of the number of years of life lost (YLLs) due to
premature death in Lithuania, ischemic heart disease,
cerebrovascular disease, and self-harm were the highest
ranking causes in 2010.
Of the 25 most important causes of burden, as measured by
disability-adjusted life years (DALYs), road injury showed the
largest decrease, falling by 44% from 1990 to 2010.
The leading risk factor in Lithuania is dietary risks.
Percent decline in age−specific mortality rate
●
Age group
Males
Females
CAUSES OF PREMATURE DEATH
Years of life lost (YLLs) quantify premature mortality by weighting younger deaths more than older deaths.
Ranks for top 25 causes of YLLs 1990-2010, Lithuania
# YLLs in thousands
(% of total)
Rank and disorder 1990
227 (25.9%)
1 Ischemic heart disease
76 (8.6%)
2 Stroke
49 (5.6%)
3 Road injury
52 (5.9%)
4 Self-harm
35 (4.0%)
5 Lung cancer
28 (3.2%)
6 Congenital anomalies
25 (2.8%)
7 Stomach cancer
25 (2.9%)
8 Alcohol use disorders
23 (2.6%)
9 Drowning
23 (2.6%)
10 COPD
14 (1.6%)
11 Falls
14 (1.6%)
12 Colorectal cancer
14 (1.6%)
13 Interpersonal violence
14 (1.5%)
14 Breast cancer
12 (1.4%)
15 Lower respiratory infections
11 (1.3%)
16 Cardiomyopathy
11 (1.3%)
17 Cirrhosis
10 (1.2%)
18 Preterm birth complications
10 (1.1%)
19 Rheumatic heart disease
9 (1.0%)
20 Tuberculosis
9 (1.0%)
21 Mechanical forces
9 (1.0%)
22 Poisonings
8 (1.0%)
23 Pancreatic cancer
8 (1.0%)
24 Leukemia
7 (0.8%)
25 Neonatal encephalopathy
27 Ovarian cancer
28 Brain cancer
31 Hypertensive heart disease
32 Kidney cancers
38 Other cardio & circulatory
http://www.healthmetricsandevaluation.org
Rank and disorder 2010
1 Ischemic heart disease
2 Stroke
3 Self-harm
4 Lung cancer
5 Cirrhosis
6 Road injury
7 Alcohol use disorders
8 Cardiomyopathy
9 Colorectal cancer
10 Drowning
11 Falls
12 Stomach cancer
13 Interpersonal violence
14 Lower respiratory infections
15 Breast cancer
16 COPD
17 Pancreatic cancer
18 Other cardio & circulatory
19 Tuberculosis
20 Congenital anomalies
21 Kidney cancers
22 Hypertensive heart disease
23 Brain cancer
24 Leukemia
25 Ovarian cancer
27 Poisonings
40 Mechanical forces
42 Rheumatic heart disease
43 Preterm birth complications
53 Neonatal encephalopathy
# YLLs in thousands
(% of total)
% change
195 (25.9%)
-15
71 (9.5%)
-2
48 (6.4%)
-6
28 (3.7%)
-24
28 (3.7%)
218
25 (3.4%)
-51
22 (2.9%)
-32
18 (2.3%)
65
17 (2.2%)
16
14 (1.9%)
-40
14 (1.8%)
-4
14 (1.8%)
-43
14 (1.8%)
-2
13 (1.7%)
25
12 (1.6%)
-13
12 (1.6%)
-49
9 (1.2%)
10
8 (1.1%)
136
8 (1.1%)
-7
7 (0.9%)
-76
7 (0.9%)
49
6 (0.8%)
49
6 (0.8%)
27
6 (0.8%)
-26
6 (0.8%)
-1
This chart shows the
change in the top 25
causes of YLLs due to
premature mortality
from 1990 to 2010.
Solid lines indicate a
cause has moved up in
rank or stayed the
same. Broken lines
indicate a cause has
moved down in rank.
The causes are color
coded by blue for
non-communicable
diseases, green for
injuries, and red for
communicable,
maternal, neonatal, and
nutritional causes of
death.
Lithuania | GBD | page 1
YEARS LIVED WITH DISABILITY (YLDs)
Years lived with disability (YLDs) are estimated by weighting the prevalence of different conditions based on severity. The top five leading
causes of YLDs in Lithuania are low back pain, major depressive disorder, other musculoskeletal disorders, neck pain, and diabetes
mellitus.
Lithuania YLDs by cause and age 2010
40,000
War & disaster
Intentional injuries
Unintentional injuries
Transport injuries
30,000
Other non−communicable
Musculoskeletal disorders
Diabetes/urogen/blood/endo
Mental & behavioral disorders
Neurological disorders
YLDs
The size of the colored
portion in each bar
represents the number of
YLDs attributable to each
cause. The height of each bar
shows which age groups had
the most YLDs in 2010. The
causes are aggregated. For
example, musculoskeletal
disorders include low back
pain and neck pain.
Digestive diseases
Cirrhosis
20,000
Chronic respiratory diseases
Cardio & circulatory diseases
Cancer
Other communicable
Nutritional deficiencies
Neonatal disorders
10,000
Maternal disorders
NTD & malaria
Diarrhea/LRI/other infectious
HIV/AIDS & tuberculosis
0−
6
7− da
28 27 ys
−3 da
64 ys
1− da
4 ys
5− yea
10 9 y rs
−1 ea
15 4 y rs
−1 ea
20 9 y rs
−2 ea
25 4 y rs
−2 ea
30 9 y rs
−3 ea
35 4 y rs
−3 ea
40 9 y rs
−4 ea
45 4 y rs
−4 ea
50 9 y rs
−5 ea
55 4 y rs
−5 ea
60 9 y rs
−6 ea
65 4 y rs
−6 ea
70 9 y rs
−7 ea
75 4 y rs
−7 ea
9 rs
80 yea
+ rs
ye
ar
s
0
DISABILITY-ADJUSTED LIFE YEARS (DALYs)
Disability-adjusted life years (DALYs) quantify both premature mortality (YLLs) and disability (YLDs) within a population. In Lithuania, the
top three causes of DALYs in 2010 were ischemic heart disease, cerebrovascular disease, and low back pain. Two causes that appeared in
the 10 leading causes of DALYs in 2010 and not 1990 were cirrhosis of the liver and falls.
CC Non-communicable
17
19
OTHER CARDIO & CIRCULATORY
22
21
24
25
BREAST CANCER
20
18
16
LOWER RESPIRATORY INFECTIONS
DRUG USE DISORDERS
COLORECTAL CANCER
15
14
MIGRAINE
13
23
STOMACH CANCER
COPD
12
OSTEOARTHRITIS
DIABETES
11
DROWNING
LUNG CANCER
ROAD INJURY
MAJOR DEPRESSIVE DISORDER
ALCOHOL USE DISORDERS
SELF-HARM
STROKE
ISCHEMIC HEART DISEASE
-50
10
INTERPERSONAL VIOLENCE
9
8
CARDIOMYOPATHY
7
NECK PAIN
6
OTHER MUSCULOSKELETAL
LOW BACK PAIN
5
FALLS
CIRRHOSIS
150
50
100
4
3
-150
CC Communicable, maternal, neonatal, and nutritional
2
0
1
-100
Percent change 1990-2010
The top 25 causes of DALYs
are ranked from left to right
in order of the number of
DALYs they contributed in
2010. Bars going up show the
percent by which DALYs have
increased since 1990. Bars
going down show the percent
by which DALYs have
decreased. Globally,
non-communicable diseases
and injuries are generally on
the rise, while communicable,
maternal, neonatal, and
nutritional causes of DALYs
are generally on the decline.
200
Leading causes of DALYs and percent change 1990 to 2010 for Lithuania
-200
CC Injuries
http://www.healthmetricsandevaluation.org
Lithuania | GBD | page 2
RISK FACTORS
Overall, the three risk factors that account for the most disease burden in Lithuania are dietary risks, high blood pressure, and alcohol
use. The leading risk factors for children under 5 and adults aged 15-49 years were iron deficiency and alcohol use, respectively, in 2010.
Burden of disease attributable to 15 leading risk factors in 2010, expressed as a percentage of Lithuania DALYs
Dietary risks
High blood pressure
War & disaster
Alcohol use
The graph shows the top 15
risk factors for Lithuania. The
colored portion of each bar
represents the specific
diseases attributable to that
risk factor while bar size
represents the percentage of
DALYs linked to specific risk
factors.
Intentional injuries
Unintentional injuries
High body−mass index
Transport injuries
Other non−communicable
Smoking
Musculoskeletal disorders
Diabetes/urogen/blood/endo
Physical inactivity
Mental & behavioral disorders
Neurological disorders
High total cholesterol
Digestive diseases
High fasting plasma glucose
Cirrhosis
Chronic respiratory diseases
Ambient PM pollution
Cardio & circulatory diseases
Cancer
Occupational risks
Other communicable
Nutritional deficiencies
Household air pollution
Neonatal disorders
Maternal disorders
Drug use
NTD & malaria
Diarrhea/LRI/other infectious
Iron deficiency
HIV/AIDS & tuberculosis
Intimate partner violence
Lead
0
5
10
15
% DALYs attributable to risk factors
20
COUNTRY BENCHMARKING OF BURDEN OF DISEASE
Understanding the relative performance of Lithuania against other comparator countries provides key insight into public health
successes and areas where Lithuania might be falling behind. The table identifies Lithuania's rank across 14 other comparator countries,
selected and ordered by income per capita, for five metrics of interest, with 1 indicating the best rank and 15 indicating the worst rank.
● Age-standardized rates are used to make meaningful comparisons across time by adjusting for changes in population size and age
structure.
● Life expectancy incorporates mortality, and health-adjusted life expectancy further incorporates years lived in less than ideal health.
● In 2010, Lithuania ranked 7th for age-standardized YLD rate and 12th for age-standardized YLL rate.
Country
Age-standardized death rates, YLL rates, YLD rates, and life expectancy at birth and health-adjusted life expectancy at birth for 1990 and 2010, both sexes combined
Age-standardized death rate
Age-standardized YLL rate
Age-standardized YLD rate
Health-adjusted life
Life expectancy at birth
(per 100,000)
(per 100,000)
(per 100,000)
expectancy at birth
1990
2010
1990
2010
1990
2010
1990
2010
1990
2010
Rate
Rank
Rate
Rank
Rate
Rank
Rate
Rank
Rate
Rank
Rate
Rank
LE
Rank
LE
Rank
HALE
Rank
HALE
Slovakia
893
10
652
9
20,667
7
13,779
4
11,905
9
11,042
4
71
9
75.4
8
61.2
10
65.4
7
Hungary
970
14
694
11
23,806
13
15,271
8
11,665
7
11,589
10
69.4
13
74.5
10
60.2
13
64.2
10
Estonia
910
11
603
6
23,443
11
13,954
6
11,129
2
11,165
5
69.8
11
75.9
6
61
11
65.7
6
Antigua and Barbuda
728
2
593
4
19,168
2
13,919
5
12,425
13
13,535
14
73.1
1
76.5
3
62.7
4
63.3
12
Croatia
830
7
585
2
19,273
3
11,918
2
12,083
12
11,620
11
71.9
5
76.7
2
61.8
6
66
5
Libya
693
1
645
8
19,723
5
15,897
10
13,033
14
13,106
13
72.7
3
74.7
9
61.3
9
62.9
13
Poland
872
9
589
3
21,136
9
13,059
3
11,652
6
11,401
8
70.9
10
76.3
4
61.5
8
66.1
4
Lithuania
833
8
678
10
21,127
8
16,608
12
11,684
8
11,302
7
71.3
8
74.1
11
61.7
7
64.3
9
Latvia
914
12
703
12
23,599
12
16,613
13
11,911
10
11,751
12
69.8
12
73.9
12
60.4
12
63.8
11
Russia
953
13
952
14
25,715
14
25,387
14
11,536
5
11,444
9
68.7
14
68.9
14
59.7
14
59.9
14
Mexico
740
4
604
7
22,775
10
15,658
9
10,092
1
9,364
1
71.5
7
75.5
7
63
3
66.9
2
Chile
760
5
490
1
18,210
1
11,136
1
11,185
4
10,407
2
72.9
2
78.5
1
63.4
1
68.6
1
1,312
15
1,432
15
46,033
15
49,393
15
14,356
15
14,462
15
60
15
58.7
15
50.8
15
49.8
15
Gabon
Rank
Malaysia
825
6
726
13
19,850
6
16,000
11
11,926
11
11,186
6
71.6
6
73.7
13
62.1
5
64.4
8
Argentina
731
3
597
5
19,400
4
14,343
7
11,154
3
10,843
3
72.5
4
76
5
63.2
2
66.1
3
http://www.healthmetricsandevaluation.org
Lithuania | GBD | page 3
COUNTRY BENCHMARKING OF BURDEN OF DISEASE, CONTINUED
This figure shows the rank of Lithuania relative to the same comparator countries for the leading causes of DALYs in 1990 (top) and 2010
(bottom).
● The columns are ordered by the absolute number of DALYs in Lithuania for that particular year, with greatest burden on the left.
● The numbers indicate the rank across countries for each cause in terms of age-standardized DALY rates, with 1 as the best
performance and 15 as the worst.
Latvia
Russia
Mexico
Chile
Gabon
Malaysia
Preterm birth complications
Rheumatic heart disease
Lower respiratory infections
Colorectal cancer
Interpersonal violence
Iron-deficiency anemia
Other musculoskeletal
Stomach cancer
Congenital anomalies
Alcohol use disorders
Major depressive disorder
Low back pain
7
3
13
4
14
9
6
3
6
8
3
3
14
8
10
15
13
2
6
1
11
9
14
13
2
15
10
5
12
15
8
8
13
4
13
7
13
10
12
9
3
2
9
5
13
15
11
14
12
3
6
14
11
9
4
6
9
12
3
3
7
8
10
1
10
3
12
2
10
6
14
12
4
1
6
1
12
1
3
2
10
6
10
9
5
5
6
4
7
14
6
15
4
7
6
3
12
6
9
8
2
8
12
12
10
1
4
14
4
8
9
5
14
9
8
8
14
1
8
15
3
1
10
9
11
4
14
15
9
5
13
1
7
2
7
1
4
1
5
13
11
6
5
2
4
2
9
1
10
11
5
3
13
15
11
14
11
11
9
12
15
3
13
13
14
10
11
15
11
7
9
15
13
10
4
8
9
10
11
11
12
11
12
14
15
9
12
9
8
1
4
8
7
9
12
8
10
13
11
1
4
9
10
6
5
13
15
1
5
11
1
15
1
12
5
9
1
13
3
12
2
11
6
12
7
11
3
13
7
4
1
15
4
12
10
8
11
11
3
2
15
10
11
14
15
13
1
7
2
9
14
7
5
7
14
12
3
8
10
2
4
2
9
3
15
4
6
9
5
4
13
8
2
5
15
5
2
6
14
6
9
14
3
1
11
14
10
15
13
5
12
1
14
10
11
5
4
5
3
13
15
1
4
2
8
5
8
7
15
12
7
6
2
1
3
7
10
2
13
Breast cancer
10
Drowning
7
14
12
Falls
13
15
7
Lung cancer
6
7
11
COPD
7
12
11
Self-harm
13
10
14
Road injury
Osteoarthritis
Poland
Lithuania
Migraine
Croatia
Libya
Diabetes
Estonia
Antigua and Barbuda
Neck pain
Slovakia
Hungary
Stroke
Country
Ischemic heart disease
Ranking of leading age-standardized rates of disability-adjusted life years (DALYs) relative to comparator countries in 1990
Alcohol use disorders
Major depressive disorder
Road injury
Cirrhosis
Lung cancer
Falls
COPD
Diabetes
Cardiomyopathy
Neck pain
Colorectal cancer
Osteoarthritis
Interpersonal violence
Drug use disorders
Drowning
Lower respiratory infections
Stomach cancer
Other cardio & circulatory
Migraine
Breast cancer
13
15
6
13
7
6
3
2
5
4
10
13
11
15
13
15
6
13
4
10
3
9
5
10
12
9
14
15
11
13
6
2
1
2
3
2
9
1
7
10
10
9
15
13
8
14
8
3
5
4
7
3
10
1
13
10
11
12
2
1
4
3
8
1
7
5
1
2
5
14
10
8
12
4
10
3
7
6
7
9
9
7
15
14
10
8
3
7
11
2
5
14
11
8
7
6
6
11
8
12
12
8
8
2
4
1
13
15
9
14
8
2
13
4
12
4
8
12
8
15
5
1
6
7
8
1
13
2
10
15
1
4
6
7
1
5
2
10
9
3
6
15
12
3
10
5
7
13
10
7
14
11
11
15
11
15
4
6
10
12
7
12
14
9
14
11
9
4
7
2
4
7
8
14
11
5
11
8
12
4
3
12
5
12
6
15
4
6
8
12
7
8
14
9
9
12
Russia
14
15
13
15
10
9
12
14
12
14
9
10
7
13
5
11
10
12
9
8
3
11
6
3
6
11
15
13
7
6
9
12
6
5
10
14
9
13
12
13
5
12
13
15
4
1
10
7
11
13
Mexico
Chile
2
1
1
2
1
5
4
9
5
9
1
5
11
3
14
9
2
5
1
3
7
5
13
1
12
14
1
2
4
14
1
4
14
2
15
8
4
8
9
4
11
8
5
14
2
3
5
1
1
2
Gabon
Malaysia
5
9
14
11
6
2
7
3
2
3
14
8
15
8
15
1
3
6
10
6
15
14
12
11
13
2
11
3
13
2
3
5
8
1
13
5
11
3
14
11
15
14
4
1
13
11
4
6
4
3
Argentina
4
3
4
5
8
7
6
6
7
2
10
9
15
9
15
10
3
11
10
7
13
6
12
2
15
Hungary
Estonia
Antigua and Barbuda
Croatia
Libya
Poland
Lithuania
Latvia
Ranking Legend
1-3
Institute for Health Metrics and Evaluation
2301 Fifth Ave., Suite 600
Seattle, WA 98121 USA
4-7
8 - 11
Other musculoskeletal
Self-harm
6
9
Slovakia
Stroke
12
10
Country
Ischemic heart disease
Low back pain
6
6
4
2
4
8
3
14
6
2
7
2
8
2
2
10
13
1
6
4
5
4
2
5
6
5
5
8
7
8
3
5
3
15
14
7
12
8
7
15
Argentina
Ranking of leading age-standardized rates of disability-adjusted life years (DALYs) relative to comparator countries in 2010
12 - 15
Telephone: +1-206-897-2800
E-mail: [email protected]
www.healthmetricsandevaluation.org
Lithuania | GBD | page 4