Integrative human cardiovascular control
Ph.D. course
The Panum Institute, University of Copenhagen
May 4 – 9, 2015
Here is the program for the course. Please feel free to change titles of your presentations and eventually
also the day if any other day is better and come forward with any other suggestions
Monday
Panum
Institute
42.0.01
9:30 - 10.25
10.30 - 12
12 - 13
13 - 16
Evening
Tuesday
Panum
Institute
42.0.01
8:30 - 9:30
9:45 - 10.30
Speaker and topic
Welcome and introduction to the program –
presentation of participants and speakers
Integrative cardiovascular physiology. A primer to
hypothesis-driven research - Regulation of skin blood
flow - Craig Crandall PhD, University of Texas
Southwestern Medical Center, Dallas, Texas, USA
Lunch
Workshop: Hypothesis-driven research in
cardiovascular physiology: Presenting and discussion
of participants own projects. Introduction by Lars
Nybo (15 min) followed by group work: 3-4 students
(each with a speaker as “supervisor”): Students give
their presentations in a group, the projects and
techniques of presentation are discussed (approx 45
min for each presentation) – Carsten Lundby, Lars
Nybo, Johannes Van Lieshout, Peter Raven, James
Fisher
Social dinner Bagsværd
Speaker - topic: central circulation
Determination of cardiac output at rest and during
exercise - Carsten Lundby PhD, Zürich and Johannes
Van Lieshout MD, DMSc , University of Amsterdam,
Holland
MRI Evaluation of Cardiac function and the coronary
Background literature assignments
Formulation of questions/issues
central to participants research.
Plan for groups – and schedule
for presentations
Background literature assignments
10.45 - 11.30
11.30 - 12.15
12.15 - 13
13 - 15.30
15.45 - 16.30
Evening
circulation and metabolism – Per L Madsen MD,
DMSc, Copenhagen
Blood pressure and control - arterial baroreflex.
Peter Raven, PhD, University of North Texas, Fort
Worth, USA
Workshop: Cardiac output and blood pressure
regulation at rest and during exercise – baroreceptor
reflex -,Lars Nybo/Peter Raven/James Fisher
Lunch (RH)
ECHO Doppler evaluations of the heart and
assessment of peripheral circulation– Per L Madsen
and Kim Bredahl, MD, PhD
Discussion of the workshop and round-up of related
presentations
Social networking – time on your own
Wednesday
Panum Institute
42.0.01
8:30 - 9:30
9:45 - 10.30
10.45 - 11.30
11.30 - 12.30
12.30 - 13.30
13.30 –-14.15
14.15 - 16.30
Thursday
Panum
Institute
42.0.11
8:30 - 9:30
Participants design of
experiments - description of
methods and set-up
Speaker - topic: special circulations – focus on
cerebral blood flow and skin circulation
Background literature assignments
Peripheral resistance, sympathetic activity and
methods to assess sympathetic nerve activity –
Paul Fadel PhD, University of Missouri, USA
Orthostatic intolerance – Woulter Wieling MD,
DMSc, Amsterdam, The Netherlands
Cerebral blood flow and oxygenation – static and
dynamic autoregulation – orthostatic stress.
Johannes Van Lieshout
Cardiovascular regulation during heat stress –
changes in skin and cerebral perfusion, orthostatic
tolerance and cardiac output Lars Nybo and Craig
Crandall,
Lunch
Do free oxygen radical influence CBF? Damian
Bailey, University of South Wales
Workshop: Cerebral blood flow and orthostatic
Participants design of experiments
tolerance – Lars Nybo, Johannes van Lieshout and - description of methods and setCraig Crandall and discussion and round-up of
up
workshop
Speaker - topic: special circulation – muscle
perfusion, oxygenation and metabolism
Regulation of muscle blood flow and methods of
importance for evaluating leg blood flow – Stefan
Background literature assignments
9:30 - 10.15
10.30 - 11.30
11.30 - 12.30
12.30 - 13.30
13.30 - 16.00
16.00 - 16.30
Friday
Panum
Institute
42.0.11
8:30 - 9:30
9:45 - 10.30
10.45 - 11.30
11.30 - 12.30
12.30 - 13.30
13.30 - 16.30
Evening
Saturday
Panum
Institute
42.0.01
9:00 - 10.00
10.15 - 12.00
12.00 - 13.00
Mortensen, University of Southern Denmark
Substances of importance for endothelial function,
vasodilation, sympatolysis at rest and during
exercise – Ylva Hellsten PhD, Copenhagen
The exercise pressor reflex – interaction between
cardiac output and muscle metabolism and blood
flow – James Fisher, University of Birmingham, UK
Leg blood flow during exercise – influence of
dehydration and heat stress. - Jose GonzalezAlonso PhD, Brunel University, UK
Lunch
Workshop: Muscle blood flow – at rest and during
exercise - young vs. elderly – Lars Nybo, Stefan
Mortensen
Perspectives of the workshop
Speaker - topic: pathophysiological responses and
special issues
Background literature assignments
Endothelia function in health and disease - Sisse
Ostrowski MD, PhD, DMSc, Copenhagen
Genetic influence on the circulation – Niels V Olsen
MD, DMSc, Copenhagen
Central blood volume and maintenance of cardiac
output, pressure and organ perfusion during surgery.
Niels H. Secher, MD, DMSc
Organ blood flow and metabolism – Gerrit van Hall
PhD, Copenhagen
Lunch
Social event
Dinner: Regattapavillonen, Bagsværd
Agenda
Integrative cardiovascular aspects – Lars Nybo
(questions. and discussion of topics from the week)
Group examination – Lars Nybo
Lunch and evaluation
Background literature assignments