Australian Indigenous HealthPlain Language From the Australian Indigenous HealthInfoNet Background information of kidney disease among Indigenous people What are kidneys? Contents Kidneys are important organs that get rid of waste from our blood and keep the water in our body balanced [1]. This waste leaves the body as urine (also known as wee). What are kidneys?�������������������������������������������������������������������������������������� 1 Most people have two kidneys, which are located on the right and left side at the back of the abdomen (the middle part of the body) just below the chest and rib cage. Each kidney is about 11.5 centimetres long, 5-7.5 centimetres broad and 5 centimetres thick, and weighs about 150 grams [1, 2]. Why do kidneys stop working?������������������������������������������������������������ 2 What do kidneys do?��������������������������������������������������������������������������������� 1 How do kidneys work?����������������������������������������������������������������������������� 1 How can we keep kidneys healthy?��������������������������������������������������� 2 What type of kidney health problems are there?������������������������ 2 Renal Disorders�������������������������������������������������������������������������������������������� 2 Urinary tract problems������������������������������������������������������������������������������� 2 References����������������������������������������������������������������������������������������������������� 3 What do kidneys do? The kidneys do many things to keep us alive and healthy [1]. • They carry away waste from the blood and get rid of it in urine. • They adjust the amount of fluid in our bodies. • They help control blood pressure by making a chemical called renin (which raises blood pressure) [1]. • They send out other chemicals to help keep the body balanced. How do kidneys work? The kidneys clean all blood in the body every two minutes. They do this by filtering the blood with small groups of blood vessels (known as a glomerulus - which is from the Greek word for filter - the plural is glomeruli) [1]. There are about 1 million glomeruli in each kidney. Blood is filtered in the glomerulus, and water and wastes are passed out as urine. Urine collects in the middle of each kidney (an area called the renal pelvis) [3]. The kidneys make more urine when there is too much fluid in the body, and less urine when CORE FUNDING More detailed information about kidney disease in Indigenous people can be found at: http://www.healthinfonet.ecu.edu.au/kidney_review and (b) glomerulonephritis. the body needs fluids (for example when you are dehydrated) [1]. The water passing from the body as urine passes through the ureters (two thin-walled tubes of around 30 centimetres in length) into the bladder (a muscular container with a capacity of around 500 millilitres) [2]. This urine is stored in the bladder and then leaves the body through the urethra (a small passage from the bladder to the outside of the body) [3]. Why do kidneys stop working? Our kidneys may stop working for a number of reasons [1]; • high blood pressure (also known as hypertension), which causes blood vessels in the kidneys to get skinny and hard so the kidneys don’t get enough blood, • infections, which spread through the blood and make the kidneys sick, • having diabetes (see diabetes section) for many years, and • genetics - some people are more likely to have problems with their kidneys because of something that’s inherited (other people in their family may have similar problems). How can we keep kidneys healthy? Things we can do to keep our kidneys healthy [4]; • keep our homes clean and free from germs, • keep our stress levels low (try to be calm, not get too excited or angry), • have regular exercise, • eat plenty of fresh, healthy food and limit the amount of fatty and take-away food we eat, • limit the amount of alcohol and tobacco we use, and • drink lots of clean water. What type of kidney health problems are there? As you know, there are two main parts of the body involved in filtering blood and waste and in the passing of urine - the kidneys and the urinary tract (ureters). These parts make up what is known as the urinary system. 2problems that damage the urinary tract (for example; urinary tract infection). Renal Disorders End-stage renal disease (ESRD) Chronic renal failure is the slow loss of kidney function that gradually gets worse over several years until the kidneys stop working for good. This is also known as end-stage renal disease (ESRD) [2]. People with ESRD need dialysis (a medical procedure that does the work of the kidneys) or a transplant (a new healthy kidney put into the body). If left untreated, ESRD leads to death. Glomerulonephritis Glomerulonephritis is a sickness that causes damage to the glomerulus [5, 6]. Damaged glomeruli let protein and red blood cells leak into the urine, and may stop waste from being properly filtered out of the body [1]. This can lead to fluid build-up in the body causing swelling in parts of the body (for example, face, hands, ankles and feet). Sicknesses related to glomerulonephritis include; acute post-streptococcal glomerulonephritis ( APSGN) (an inflammation of the glomeruli following an infection, such as one in the throat). Urinary tract problems Urinary tract infection (UTI) A urinary tract infection (UTI) is an infection or sickness in the upper or lower part of the urinary tract [1]. Usually, a UTI is caused by bacteria (tiny germs that can be killed with antibiotic medicine). Bacteria can enter the urethra and travel to the bladder, but they usually get flushed out with urine without causing an infection. Sometimes, however, the bacteria multiply and cause an infection. Women are more likely to get this infection than men, and older people are more likely than younger people. Some people with a UTI do not show signs of having it. The signs for lower UTI are; • frequent urination, • painful urination, and • tenderness in the lower pelvic area [6]. The signs for an upper UTI infection are; There are two types of problems (or disorders) of the urinary system; • fever, • back or loin pain, and 1 problems that damage the kidneys (known as renal disorders for example; (a) renal failure or end-stage renal disease (ESRD) • chills [5, 6]. 2 Copyright © 2008 Australian Indigenous HealthInfoNet Having a UTI is not always a serious problem, but having it often, having it for a long period of time and/or having it at the same time as other sicknesses (such as diabetes) can lead to more serious kidney damage. References 1. National Kidney and Urologic Diseases Information Clearinghouse (2009) The kidneys and how they work. Retrieved 2009 from http:// kidney.niddk.nih.gov/kudiseases/pubs/pdf/yourkidneys.pdf 2. Thomas CL, ed. (1997) Taber’s cyclopedic medical dictionary. Philadelphia, PA: FA Davis 3. Dictionarycom (2007) Dictionary.com. Retrieved from http:// dictionary.reference.com/ 4. Centre for Disease Control (2010) Northern Territory guidelines for acute post-streptococcal glomerulonephritis. Casuarina: Department of Health and Community Services, Northern Territory Government 5. Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL, eds. (2001) Harrison’s principles of internal medicine. New York: McGraw-Hill 6. Kumar PJ, Clark ML, eds. (1994) Clinical medicine: a textbook for medical students and doctors. London: Bailliere Tindall 3 Australian Indigenous HealthInfoNet The Australian Indigenous HealthInfoNet is an innovative Internet resource that contributes to ‘closing the gap’ in health between Indigenous and other Australians by informing practice and policy in Indigenous health. Two concepts underpin the HealthInfoNet’s work. The first is evidence-informed decision-making, whereby practitioners and policy-makers have access to the best available research and other information. This concept is linked with that of translational research (TR), which involves making research and other information available in a form that has immediate, practical utility. Implementation of these two concepts involves synthesis, exchange and ethical application of knowledge through ongoing interaction with key stakeholders. The HealthInfoNet’s work in TR at a population-health level, in which it is at the forefront internationally, addresses the knowledge needs of a wide range of potential users, including policy-makers, health service providers, program managers, clinicians, Indigenous health workers, and other health professionals. The HealthInfoNet also provides easyto-read and summarised material for students and the general community. 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Director Professor Neil Thomson Address Australian Indigenous HealthInfoNet Edith Cowan University 2 Bradford Street Mount Lawley, WA 6050 Telephone (08) 9370 6336 Facsimile (08) 9370 6022 [email protected] Web www.healthinfonet.ecu.edu.au F e at u r e d A rt wo r k Alup by Billy Missi © Australian Indigenous HealthInfoNet 2013 This product, excluding the Australian Indigenous HealthInfoNet logo, artwork, and any material owned by a third party or protected by a trademark, has been released under a Creative Commons BY-NC-ND 3.0 (CC BY-NC-ND 3.0) licence. Excluded material owned by third parties may include, for example, design and layout, images obtained under licence from third parties and signatures. CORE FUNDING
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