MEDI CA L I NDI CATI ON S K EY BENEFITS Multiple Indications for a Wide Range of Patients Healthy Weight Loss Satiety Support • Formulated with high insoluble fiber to add dietary bulk without calories to promote satiety or feeling of fullness Fiber responsive colitis • Formulated with low calorie content and a unique nutritional profile: with high % of calories coming from protein, stimulating metabolism, promoting fat loss and helping maintain lean body mass (Figure 1) Diabetes mellitus in overweight dogs • High total protein levels promote healthy weight loss Obesity (weight loss and weight maintenance) Constipation Weight Regain Management • Isoflavones from soybean germ meal help reduce the risk of weight regain and fat accumulation (Figure 3) Great Taste Hyperlipidemia in overweight dogs • Variety of kibble textures and complementary treat offering to help with long-term compliance and weight loss success HOW DOES PURINA COMPARE? WEIGHT MANAGEMENT CANINE DRY FORMULAS PPVD OM PPVD OM SELECT BLEND HILL’S W/D WITH CHICKEN HILL’S METABOLIC CHICKEN FLAVOR HILL’S R/D RC SATIETY SUPPORT Total calorie Kcal/cup 266 235 239 260 242 245 Total calorie Kcal/kg 2624 2710 2928 3157 2968 2880 Caloric profile on ME basis protein/fat/CHO (% of calories) 32.8/18.2/49.0 32.6/17.0/50.4 21/23/56 29/30/41 37/22/41 36/28/36 Protein content (g/100 Kcal) 10.50 9.96 5.8 8.2 10.6 11.03 Fat content (g/100 Kcal) 2.41 2.14 2.7 3.6 2.5 3.49 High insoluble fiber for increased dietary bulk without calories (g/100 Kcal) 7.85 7.20 8.8 Not published 7.2 Not published With guaranteed isoflavone level to help manage weight rebound Yes Yes No* No* No* No* Animal feeding test using AAFCO procedures Yes Yes Yes Yes Intermittent or Supplemental Feeding No *Isoflavones may be present but level is not guaranteed. PPVD Product Guide 2015 (Average Nutrient Content), Hill’s Key 2016 (Average Nutrient Contents), Royal Canin Product Guide 2016 (Typical Analysis) RESEARCH AND RESULTS THE SCIENCE THAT SETS US APART PURINA ® PRO PLAN ® VETERINARY DIETS OM CANINE INCREASED DIETARY PROTEIN STUDY INCREASED DIETARY PROTEIN = INCREASED FAT LOSS IN DOGS Figure 1 Hannah, S. & Laflamme, D. Increased dietary protein spares lean body mass during weight loss in dogs. J Vet Intern Med. 1998; 12:224. PERCENT OF WEIGHT LOSS LEAN In a clinical study, increased dietary protein spared lean body mass and facilitated greater fat loss in dogs during weight loss RESULTS OF MULTI-MONTH AT-HOME FEEDING TRIAL Figure 2 FAT Dogs eating OMover 3 months (n = 8 dogs) 100 85.3 78.5 80 Feeding portions were determined by using the proprietary Purina Veterinary Feeding Program. The study targeted 1.5 – 2.0% weight loss for canine participants. 65.7 60 40 33.5 20.8 20% 20 13.5 30% 16.2% AVERAGE PERCENTAGE OF WEIGHT LOSS: Project Pet Slim Down Trial Results: Canine Trials concluded in March 2010. 39% 0 PERCENTAGE OF WEIGHT LOSS RANGE: P≤ 0.05 11.5% - 21.8% DIETARY PROTEIN (% OF CALORIES) ISOFLAVONES IMPACT STUDY ISOFLAVONES SIGNIFICANTLY R EDUCED FAT ACCUMULATION IN SPAYED AND NEUTERED DOGS Pan, Y. Use of soy isoflavones for weight management in spayed/ neutered dogs: Nestlé Purina Research, the FASEB Journal. 2006; 20:A854-A855 Pan, Y. Effects of isoflavones on body fat accumulation in neutered male and female dogs: Nestlé Purina Research, the FASEB Journal. 2007; 21:551.20 CONTROL CHANGES IN % OF BODY FAT (%) Isoflavones in OM Canine dry help reduce the risk of weight rebound ISOFLAVONES SIGNIFICANTLY REDUCED WEIGHT GAIN IN SPAYED AND NEUTERED DOGS ISOFLAVONES CONTROL 20 12.75 11.45 9.08 2.75 15 5.14 1.76 4.03 * * * 10 5 0 -5 -2.31 3 6 9 MONTHS 12 -10 *P<0.05 CHANGES IN BODY WEIGHT (KG) Figure 3 ISOFLAVONES 5.54 7 4.99 6 3.64 2.16 * * 1.43 1.10 2.68 5 4 3 2 1 0 -1 -0.15 3 6 9 MONTHS 12 -2 *P<0.04 For more information, visit www.PurinaProPlanVets.com or call us at 1-800-222-VETS (8387), 8:00 a.m. - 4:30 p.m. CST, Monday-Friday. Purina trademarks are owned by Société des Produits Nestlé S.A. Any other marks are property of their respective owners. Printed in USA. VET5949A-0516
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