Extended Project Dissertation The Concept of Designer Babies is no different to Hitler creating an Aryan Race Word count: 7380 Candidate Number: 0282 Centre Number: 64906 1 Contents Abstract 3 Introduction 4 Main Body 7 Conclusion 24 Evaluation 26 Bibliography 28 2 Abstract The idea of designer babies has been around for centuries, but recent scientific technologies have begun to shed light on a path towards achieving the technology to create designer babies. This means it is imperative that the public understands the science and ideals behind their creation. Some types of designer baby can be seen as negative, but they are not all indisputably negative. There are some modern genetic engineering techniques that could lead to the creation of designer babies for the wrong reasons if they are developed further. However, many procedures allow for the removal of genetic disease to prevent suffering, so ruling out all types of designer babies would not be the best solution. There have been many events in history linked to eugenics and designing babies that would need to be studied in order to predict the future of genetic engineering and allow judgements to be made. Hitler’s Aryan race is not always associated with designer babies, but it is very closely linked due to mass extermination resulting in the limitation of the gene pool. 3 Introduction Throughout this essay I aim to explore the present and future prospects of genetic engineering in humans. This will include looking back at groups in history who have tried to create a ‘perfect humanity’, such as the Nazis and the American government. The general public do not have positive views of such a concept, as the media present extreme views of worsecase outcomes. Thus there is considerable objection to any step forward in human genetic engineering. A well-known view of eugenics comes from the implications of ‘negative eugenics’, which refers to the eradication of undesired characteristics, demonstrated by the eugenics movements in the US and Germany during the 20th Century. However, ‘positive eugenics’ is not necessarily all bad. It involves enabling the desired characteristics, such as encouraging healthy, intelligent people to breed together so that their genes can be passed onto the next generation. Although both types count as eugenics and are regarded as morally wrong by many people, the subtle differences between them can create the border between what is perceived to be right and wrong. I chose this title for my project because I want to discuss ethical issues associated with scientific developments. The concept of designer babies creates a moral argument involving scientists, philosophers and the rest of society. This means that I am able to incorporate many different people’s views into my essay, but can also talk about the effect that the media and governmental propaganda has on public opinion. By referring to Nazi Germany, I can explore the history of the eugenics movement and compare people’s present views to those of the past. I feel that my project is important because we can learn a lot by the mistakes that people have made in the past. The history of eugenics is riddled with what could be perceived to be mistakes, but without them we may not have the genetic technology that we have today. 4 The term ‘eugenics’ is derived from “eu” (the Greek word for good) and “genos” (meaning offspring), so it essentially means “good offspring” [Hix, 2009]. A good definition is “the study of methods of improving the quality of the human race” [The Free Dictionary, 2003]. This implies that everything that is described as ‘eugenics’ is done with the belief that it will benefit humanity. Herein lies the problem that people have faced throughout recent history; they believe they are doing the right thing. But what does ‘the right thing’ mean? As morals are subjective, people’s views are likely to differ. The International Congress on Eugenics (1921) defined eugenics as: “the self-direction of human evolution” [International Congress, 1921], which can be viewed as a positive view of eugenics, but it can also be seen as negative because some people believe that it is not our job or right to direct our own evolution. The term ‘designer baby’ has many different meanings. In 2010, the Oxford Dictionary defined it as “a baby whose genetic makeup has been artificially selected by genetic engineering... to ensure the presence or absence of particular genes or characteristics” [Oxford Dictionary, 2010]. I will discuss how my views on this definition change at the end of my essay, but originally I believed this to be a good definition because it encompasses many different techniques for genetic engineering. Generally, the reason why people object to the creation of designer babies is because it could result in people choosing to have their baby’s intelligence and physical attributes altered. However, many applications of genetic testing and engineering allow parents to ensure that their child will not inherit genetic disorders or be affected by chromosomal defects, such as Down’s syndrome. One could also say that the creation of many embryos by IVF (In Vitro Fertilisation), screening them and choosing the ‘best’ embryo(s) to be implanted (e.g. the ones without genetic defects) is effectively creating a designer baby because the embryo is being selected on the basis of desired characteristics, even though the actual 5 genetic makeup has not been changed, instead it has been chosen because it is ‘good’ in the first place. 6 What is Perfection? There are probably few people who think that there is such a thing as ‘perfect’ humanity and fewer still who think it would be a good thing if it did exist. Much of today’s society encourages us to strive to be perfect, but what is perfection? The well-known phrase “beauty is in the eye of the beholder” [Hungerford, 1878] is, in essence, the only answer to this question; perfection is subjective, so there is no right answer to the question. Some people may also argue that there is no such thing as perfection, or at least that it would be impossible for humans to reach, but should this stop us from striving for it? Surely nearing perfection would be better than not even trying? For Christians at least, this is what they are taught to strive for. The Bible teaches that Christians should endeavour to be “Christ-like” [Philippians 2:5] and “perfect” like God is perfect [Matthew 5:48]. In this case, it is probably referring to leading a sin-free life, but could be interpreted in other ways. Similarly, Dr. Siddiqi (Director of the Islamic Society of Orange County) claimed that “A Muslim is not claiming that he is perfect, but he is striving to reach that goal” [Mystic World Fellowship, 2000]. These are examples of how people come to believe they should change themselves to achieve some kind of perfection. Another example is modern society’s obsession with being physically perfect, through the media promoting the virtues of being thin and having cosmetic surgery. These factors all add up to people believing humanity needs to be flawless and may have been the catalyst for events such as the American and German Eugenics Movements. Designer Babies Reasons for creating designer babies There are many reasons why people may wish to have a designer baby. Common reasons are cosmetic; parents may want their children to be perfect, whether that means having blue eyes and blond hair or being tall and athletic. These reasons can be very materialistic and lead to 7 discrimination against anyone who is not perceived to be ‘perfect’, but can also just be parental instinct in wanting the best for their child. Parents may also wish for their offspring to be intelligent, which may benefit the child, and the individual family, but may not be beneficial for society as a whole. This is because a society filled with intelligentsia may not function well as people may be reluctant to do the more mundane, but equally essential, jobs. Another reason for wanting a designer baby is that some people possess genetic diseases and disorders that are likely to be passed down to their children. By having their embryos screened, they can ensure that the baby is clear of the gene[s] linked to in that disease. We can or may be able to screen for disorders such as Alzheimer’s, many cancers and medical conditions such as diabetes and obesity. [Johnson, 2012]. Although this prevents the inheritance of diseases and could result in the complete removal of such diseases, it involves killing the excess embryos, which means that it has some moral and ethical implications that many people do not agree with. Origins of designer babies The first idea of eugenics came from around 400BC. It was the idea of Plato, an ancient Greek philosopher, who made the suggestion of coupling parents by class in order to make the human race better. He called for “provision to be made for men and women of the same natural capacities to mate” [Galton, 1998]. He thought ‘marriage festivals’ should be introduced, which were essentially mating rituals. They were to happen every year and would involve ‘suitable’ young people (men around the age of 25 and women around the age of 20) getting ‘married’ and cohabiting for one month. These young people would then remain celibate for the rest of the year and then would ‘marry’ another partner the next year. The number of marriages each year would be monitored closely in order to keep the population constant, meaning more marriages would 8 take place after wars and natural disasters and fewer would take place if there had been an increase in births. The purpose of these marriage festivals was to encourage the more ‘superior’ and suitable people to have children and would essentially prevent people from lower classes from reproducing. The ‘benefit’ of changing partners each year was that attachment would be prevented, meaning they wouldn’t be distracted from their duties in “governing, defending or extending the city state” [Galton, 1998]. For the same reason, new-born children were to be taken away and placed into nurseries, where they would be reared by nurses. This would also allow for any “defective” children to be “hidden away” [Galton, 1998]. These ideas were not accepted by ancient Greek society partly due to them being discredited by Aristotle because they did not take human desires into account; it would be impossible to prevent people from becoming emotionally attached to their children or partners [Brake, 2012]. These marriage festivals would not have been very successful in producing a fully functioning society. Although the most suitable young people would be chosen to procreate, no record of parenthood would be referred to before they were paired up, meaning that a brother and a sister could be paired up without anyone knowing. Plato would not have known the dangers arising from this, but we now know that incestuous relations increase the chances of genetic defect, and incestuous marriages are illegal in many countries as a result of this [Minkel, 2010]. Sir Francis Galton was an English eugenicist and proto-geneticist, among many other things. He coined the word ‘eugenics’ in 1865 and was the first person to publicly discuss eugenics since Plato in 400BC. He believed that eugenics would benefit the human race and thought it was “religious duty” to allow eugenics [Galton, 1905]. He, like Plato, believed in ‘eugenic marriage’ but also had ideas about issues such as whether we should give money for disadvantaged people’s higher education. He argued that the reason for the child being disadvantaged in the first place was their 9 unintelligent family, and thus the children were unlikely to be intelligent either, and would be “intellectually unable to profit by it” [Galton, 1905]. He believed that all of his ideas were the only way forward and that “no worthier object exists for man than the improvement of his own race” [Galton, 1905], which is similar to the opinions of both those who were in charge of the American Eugenics Movement and Hitler. This makes it hard for people to judge what is right and wrong because everyone is entitled to their own opinion. It is when extreme opinions are put into practice and affect the whole of society that problems arise. If Plato and Galton’s ideas had been accepted and used by the governments of their time, the world would be a completely different place from what it is now. However, it is impossible to know if that world would be ‘better’ than ours. What does current technology allow? One current method of screening for genetic diseases is Pre-implantation Genetic Diagnosis (PGD). This technique involves the use of IVF and allows scientists to find out information about the “genetic constitution” of an embryo at an early stage [Mayor, 2003]. This is done by removing a single cell from an embryo and determining the presence/absence of selected chromosomes. PGD can be used to test for sex-linked genetic diseases (such as haemophilia), as well as single-gene disorders (such as Huntington’s disease). The test for haemophilia simply involves ensuring that any embryo that is implanted is female, because the diseases is carried on the X-chromosome, so females can be carriers of the disease but are not affected due to only having one unhealthy X-chromosome and the other one normal. Based on the information found, the healthy embryos are selected and either implanted or cryogenically stored (frozen) for future use. Any unwanted embryos are destroyed or used for research [The Reproductive Sciences Center, n.d.]. This is an extremely valuable technique because it enables couples to have healthy children when there is a low possibility of this happening naturally. However, there is still the debate over whether it is immoral to kill the unwanted embryos 10 simply because they have a disease. Is it our place to decide that their lives would not be worth living if they have a genetic disease? In recent years, sperm banks have become more widely used and now allow “couples to shop for sperm donors like an online dating service” [Chang, 2007]. It is now possible to choose your sperm donor from online catalogues, which rank the donors by religion, eye colour, occupation and many more characteristics. The London Sperm Bank catalogue even includes the donors’ dress sense [Periscope, 2011]. This means couples can effectively design their children by selecting the sperm. Many of these traits aren’t fully genetic, for example religion isn’t genetic and intelligence is only partially inherited, so selecting sperm for these reasons may not be worthwhile. Surrogacy can be a perfectly acceptable way of creating a child, but recently this simple method has been taken into the realm of designer babies. An example of this is a ‘Surrogacy Consultancy’ in India, which is “nothing less than a baby factory” [Daily Mail, 2012]. Couples (normally from the Western world) either send their sperm to fertilise the surrogate’s egg or select their ideal sperm and egg combination from various countries around the world. These are then fertilised and shipped to India, where they are implanted into the surrogate. These surrogate mothers typically make the equivalent of 10 years’ salary per baby they ‘produce’, so it is becoming a popular ‘job’. This obviously raises moral questions about selling your body, as well as those about choosing your baby’s characteristics. This is a method that could be used to prevent the inheritance of a disease, but could also be used for cosmetic reasons; donors could be chosen based on their physical attributes. One of the problems with current technology is that traits such as height and personality cannot be reliably altered and many diseases cannot be prevented because they “are the result of a complex interaction between multiple genetic and environmental factors” [Hudson, 2005]. We cannot 11 remove/change the disease or trait without affecting a significant number of genes and our current understanding and technologies do not allow us to do this with the confidence that detrimental mistakes won’t be made. Another problem is that many traits have no known cause, so nothing can be done to remove the disease because there is no target for treatment/replacement. For many diseases, it isn’t clear which genes are involved. For example, in Alzheimer’s, four genes have been identified so far that are linked to the disease, but these only account for one in a thousand Alzheimer’s cases [Alzheimer’s Society, 2012]. Nevertheless, screening for these genes may help to identify some of the people who are at risk of later development of the disease. Much more research needs to be done to understand the causes of such diseases in order for embryo screening to be useful. The complication of DNA was discussed in an article in Scientific American, which said “genes predict certain welldefined physiological diseases... but when it comes to complex human behaviours ... the link is tenuous at best” [Charney, 2012]. This was used in relation to whether voting decisions are genetic, but also could be said for other traits. This means that changing the genetic makeup of a person may not affect multifarious traits; the development of such traits may be partly or completely due to the upbringing of said person. A very recent application of designer babies is in the case of three-way IVF treatment [Roberts, 2012]. This method uses three parents to create a child and aims to prevent the inheritance of mitochondrial diseases. Much of the DNA in the gametes is contained within the nucleus of the cells and it is this that is passed onto the embryo. However, the mitochondria also contain their own DNA, so when an embryo is created, its mitochondrial DNA will be a replica of the mother’s due to only the nucleus of the sperm being used. This means that any mitochondrial disorders that the mother possesses will be passed on to the child, many of which can cause muscle failure, heart failure and blindness. In the past, women with mitochondrial diseases were only given the option of 12 using a donor egg in order to prevent their child inheriting the disease, but now there is another choice. This treatment involves using the nucleus of the mother’s egg and implanting it into the ‘shell’ of an egg from a donor with healthy mitochondria. This is then fertilised with the father’s sperm and implanted into the mother’s uterus. This method creates a child with purely the mother and fathers’ nuclear DNA, but with a donor’s healthy mitochondrial DNA. This method has currently only been used in humans up to just before implantation into the mother, but has the potential to be used in the future to help couples produce healthy children. This obviously raises many moral arguments based around who is the rightful mother. Biologically, the woman whose nuclear DNA has been used is the mother, but the donor of the ‘shell’ also helped to create the child, so it may be reasonable to say that they would have some kind of ‘ownership’ of the child. Benefits of designer babies The benefits that arise from being able to reduce suffering are indisputable. There are some arguments against removing genetic disorders from the gene pool based on whether we have the right to do so, is that ‘playing God’? [Holley, 2009]. However, there are a great many advantages of removing such diseases due to reducing the suffering of a child and creating a ‘better’ life for them. There are many genetic disorders that doctors can recognise in an embryo, but currently they can only be eradicated by killing the embryo, which is where the issues lie. A solution to all these problems could be to replace or fix the ‘faulty’ gene. An experimental method known as gene therapy is currently being researched. This will allow scientists to replace a faulty gene with a healthy one, make a faulty gene inactive or introduce a new gene into the body. Gene therapy is a promising treatment, but it is still being studied to ensure its safety and effectiveness. It is hoped that in the future it will be used to treat some cancer types and also some genetic disorders [National Institutes of Health, 2012]. If there were no more children born 13 with the genes that control certain genetic disorders, those disorders could be eradicated completely from the gene pool, meaning that it would no longer be possible for anyone to inherit that disease. It would be a huge success if this were possible, because disorders such as cystic fibrosis could be completely removed, thus saving anyone else from suffering the immense pain that comes with these diseases. It would take a long time to achieve this because, although gene therapy may be available soon, the genes would not be eradicated until every person with or carrying that disease had used gene therapy to remove it from their child. This means that it would take years to completely eradicate the disease. A saviour sibling is: “a child selected as a result of genetic screening to have some innate characteristic that will help save the life of an existing brother or sister” [World Wide Words, 2007]; their parents use a treatment such as IVF in order to make sure that the child will be a genetic match. The common reasons for wanting to produce a ‘saviour sibling’ are in the cases of genetic blood disorders and leukaemia. The saviour sibling donates stem cells, either through the use of the umbilical cord or through bone marrow donations. Firstly, embryos are fertilised in the lab and then are checked for a genetic match. Any that are a match are implanted into the mother. The main problems with this method of treatment arise when the parents treat the saviour sibling as almost a stem cell dispenser; they do not value the child as much as they would if it was born naturally. Another objection is that the child is then born without any choice over whether they want to help their sibling or not; there is no sense of free will. This is illustrated in Jodi Picoult’s novel, My Sister’s Keeper, where Anna (the saviour sibling) resents not being treated like a real person by her parents and refuses to help save her sister’s life [Picoult, 2004]. Walsh (2010) argues that the saviour sibling “owes his life to his capacity to be of therapeutic use”. This is partially true because, had his genetic make-up been slightly different, he wouldn’t 14 have been chosen and the embryo would just have been discarded. The method of using the umbilical cord is generally more ethical than that of using the bone marrow because once the child has been born and the umbilical cord has been cut, no further donations are necessary and they are able to live their life as a normal child. However, in the case of using bone marrow, the saviour child has to undergo painful extraction of their bone marrow in order to donate it to their sibling. This results in moral questions over whether it is right to put a second child through pain in order to save the life of the first. Disadvantages of designer babies It is popularly believed that even allowing the most common forms of designer babies, for example IVF and saviour siblings, creates a slippery slope and thus not a good idea. This view is normally based on what has happened in the past, through Nazi Germany and the American eugenics movement for example. New technologies are likely to encourage “a consumerist attitude towards children” [Tizzard, 2002, p.41]. This would have a detrimental effect on people’s views of their children, resulting in children being “less likely to be offered unconditional love by their parents” [Lee, 2002, p.78]. Through this, the parent-child relationship may change, becoming unnatural and superficial. Parents would have unreasonable hopes for their child; they would expect them to be perfect in ways that are not humanly possible. If this was to happen, much of society would change because many morals are based around love for one another, so in removing that, society may become entirely egocentric. This is an outcome that would be unlikely to benefit society; it would probably have unfavourable effects on the way society operates. Some treatments such as IVF can involve the ‘disposal’ of unwanted embryos, which can be regarded as murder. Anything involving potential deaths results in huge moral arguments. The main arguments against designer babies are based around the moral stance on murder and mercy 15 killing, “one should no more destroy an embryo...than one should destroy a child” [Warnock, 2002, p.32]. In George Bush’s famous speech regarding stem cells, he said “like a snowflake, each of these embryos is unique, with the unique genetic potential of an individual human being” [American Rhetoric, 2001]. It is interesting that he didn’t describe the embryo as being an “individual human being”, just that they have the potential to be. This is a widely accepted argument for the killing of embryos as a result of treatments such as IVF. Some people argue that if it is decided that killing an embryo for the sake of creating a more ‘perfect’ life is a morally acceptable thing to do, then that leaves the opportunity for a slippery slope towards accepting human experimentation and towards the ideals of people such as Hitler. The main disagreements in the case of IVF treatment are associated with the point at which life actually begins; this is imperative to the morals because it affects at what stage people believe it becomes killing a child, rather than simply disposing of a group of cells. Different groups of people have different ideas about when life begins, based on social, environmental and religious reasoning. Some people believe life begins at conception because a fertilised egg has all the characteristics of a living thing; one example of this is the Association of Pro-Life Physicians [Association of Pro-Life Physicians, n.d.]. Others believe life begins at birth or at some point during pregnancy. For many of these people, disposing of an embryo is no different to losing blood from a cut because both cases just involve cells, not actual lives. These conflicting views obviously have a huge effect on the public view of IVF treatments. In essence, there is no way of knowing for definite when life begins, it is something that people decide for themselves based on religion and morals, rather than biological fact. This means that there aren’t very many balanced arguments on this issue; most of the resources are very subjective, so cannot be used as reliable scientific evidence. 16 Designer Babies in Science Fiction Many views of designer babies are based on historical events or science fiction. Many of these portray a dystopian society once some aspect of designer babies has been allowed to flourish. For example, in many science fiction novels/films, the world becomes a place where ‘perfect’ humans are normal and natural, imperfect humans become outcasts. This is demonstrated in the popular sci-fi film Gattaca [1997], where genetically engineered people control the whole world, while ‘God Children’ (those born without modification) are predestined to have a menial job and have no hope of climbing the social/career ladder due to their genetic makeup. This idea of discrimination is something that scares many people enough to make them think that designer babies shouldn’t be allowed at all. This view is reasonable in some respects because it is discrimination such as this that was the main focus of Hitler’s eradication of the Jews; he thought they were inferior beings because of their ancestry, so took measures to rid the world of them. This was a very extreme response, but in theory it could happen if people were able to make ‘perfect’ children. Because some people would believe it wasn’t right (much like the main character’s parents in Gattaca), they would have their child naturally, resulting in them being different to everyone else, thus being outcast and discriminated against. However there is no real way of knowing what would happen to society, this is all just overexaggerated speculation and cannot be used as evidence because it was created by the writer’s imagination. On the other hand, history can provide some clues as to what society would become. Historical Examples How did Hitler aim to achieve a perfect humanity? Hitler is a good example of the possible escalation involved in wanting humanity to be ‘perfect’. He tried to eradicate anyone who he deemed to be imperfect, through making an Aryan Race. Hitler thought that the 17 perfect human (meaning an Aryan) was tall and athletic, with blond hair and blue eyes; the exact opposite of the stereotypical Jew [Hitler, 1925]. He also thought they should be free of imperfections such as disabilities. He went to extremes in the case of height; any Nazi soldier over six and a half feet was awarded a special medal and an instant promotion and applicants for any part of the Nazi program had to be at least six feet tall. Hitler believed that he was benefiting humanity and “acting in the sense of the Almighty Creator” [Burleigh and Wippermann, 1991, p.40], which shows that many events like the Holocaust that we now deem to be horrific were done with good intentions. It is only with hindsight that we can say that they were morally wrong, but at the time many people were swept up in the propaganda and believed it was the only way forward. This emphasises the subjectivity of morals and how a situation cannot fully be judged without having an outsider’s view. This is a worry for society even now. No matter how morally wrong it might be, if someone as persuasive and powerful as Hitler tried to convince our society of their mission, they would probably succeed. Once a few people are swayed, others will follow and eventually most people will be helping to aid the ‘mission’. Hitler believed that, in order to please God, he had to eradicate anyone who didn’t fit the ‘perfect human’ criteria [Joseph, 2003]. The most infamous example is the eradication of the Jewish community, but Hitler also removed anyone with physical or mental disabilities and anyone who had ‘bad blood’ (such as gypsies). In order to eliminate the Jews, Hitler started by rounding them up and putting them into concentration camps, where they were used for human experimentation and eventually shot, gassed or starved to death. He implemented laws that discriminated against the Jews; they were unable to attend school or run businesses, causing them to be uneducated and making them live in poverty, eventually resulting in their eradication because many would die of starvation due to having no money to buy food. Another method of 18 eradication was a compulsory ancestry test for all members of the public. They were given a certificate allowing marriage if the State believed that any offspring produced would be beneficial to society. Those who didn’t pass the test were deemed to be of “lesser hereditary value”, usually because of “hereditary illness” or some kind of contagious disease [Burleigh and Wippermann, 1991, p.49]. This is based around similar ideas to Plato’s ‘marriage festivals’ and possibly originated there. Anyone who didn’t ‘pass’ the test was subjected to compulsory sterilisation and isolation from the community. This ensured that any ‘negative’ characteristics, such as being Jewish, were not passed on to the next generation of Germans. In 1880, Nietzsche wrote “the tendency must be towards the rendering extinct of the wretched, the deformed, the degenerate” [Goldberg, 2007]. This reflects the general view of powerful Germans during Hitler’s dictatorship. One of the ways that disability was to be wiped out was through killing anyone who had a disability, such as children who had a deformity, who were “transferred to special ‘paediatric clinics’ where they were either starved to death or given lethal injections” [Burleigh and Wippermann, 1991, p.144]. In the majority of these cases, the parents were under the false illusion that their child would have a chance at a better life if they were sent to one of these clinics. Over the course of this ‘child euthanasia’ programme, more than 5000 children were killed who would be deemed healthy in today’s society. An alternative to actively killing ‘unwanted’ people was that “inferior persons should be sent to the front” during the war [Burleigh and Wippermann, 1991]. This was effectively killing them, but not in such an active sense as the euthanasia programmes. It also meant that fewer ‘more valuable’ Germans would be killed as a result of the war. 19 American eugenics movement The American eugenics movement was the start of ‘popular’ eugenics; it arose many years before the Nazi eugenics movement and probably was the origin of Hitler’s ideas. The main reason why the eugenics movement was able to grow so much during the early 1900s was due to propaganda. The American government used propaganda to convince the whole population of the differences between races and intelligence levels in society and that there were ‘better’ people who should be allowed to repress the ‘less valuable’ members of society. The people behind the eugenics movement thought they were introducing eugenics “as pertain to humanity’s betterment” [H. Fairchild, n.d.]. This quote is from an actual letter sent to a company by the American Eugenics Society, so it reliably shows either the actual view of the society or the message they want to give to the public. The American government claimed that the eugenics movement would improve society and supported “the forcible sterilization of the poor, disabled and ‘immoral’” [Ordover, 2003]. They tried to encourage the most ‘fit’ of society to produce many children and discouraged ‘unfit’ people from reproducing. By this they aimed to solve problems facing American society, such as crime and alcoholism. The American Eugenics Society was set up in 1922 to try to control the direction of human evolution in America and never officially ended [PBS, 1998]. The state sterilization laws were gradually removed, but all of the propaganda and hatred was never undone. One method of encouraging eugenics was incorporating it into school curricula and offering degrees in it. This meant that Americans grew up knowing that there were different classes of people, so there would be no opposition to the eugenic laws later in life [Laughlin, 1919]. The government also used a wide range of propaganda, such as posters advertising the amount of money that was being ‘wasted’ on caring for 20 ‘unfit’ people. This encouraged mass discrimination. Other methods included “Fitter Family” competitions, where families received medals and prizes for having children who were ‘free from defects’ [Pernick, 2002]. This made it worthwhile having a family that was genetically ‘pure’. A method of ‘bettering’ society was through compulsory sterilisation of anyone who was deemed to be ‘unfit’. This originated in 1927 with the sterilisation of all patients in mental hospitals. Under this regulation, over 64,000 patients were forcibly sterilised. After this, the sterilisation spread to others, including the lower classes and foreign immigrants [Reilly, 1987]. If ‘unfit’ people managed to avoid sterilisation, there were other methods of preventing reproduction, such as limiting marriage for ‘unfit’ persons. This meant that anyone who wasn’t deemed 'good' enough wasn’t allowed to reproduce, thus limiting the gene pool and essentially designing the next generation of Americans. There is no doubt that the American eugenics movement influenced the Nazi eugenic movement in some way. This is evident from the comment of a superintendent of Virginia’s Western State Hospital on the rise of Nazi compulsory sterilisations, where he said “the Germans are beating us at our own game” [Krell, 2011]. This shows that the Americans acknowledged themselves as the originators of the eugenics movement. Not only did the ideas for eugenics transfer from the US to Germany, but the American government actually funded Germany’s eugenic institutions; they paid almost $4 million to German researchers, one of whom wrote the book that gave Hitler the idea for the Aryan race [Black, 2003]. It could then be said that the Americans were partly to blame for the Holocaust because, although their ideas were slightly less extreme than Hitler’s, if it was not for them Hitler may never have come up with the idea for his mass exterminations. 21 Future Possibilities One future possibility for designer babies is the idea that whole armies could be created using genetic engineering, much like Saruman’s orcs in Lord of the Rings [2003], who are created for the sole purpose of fighting. They have no families, so there would be no necessary protocol in the event of their death and it would probably go unnoticed. In the same way, we could use genetic engineering to create an army of soldiers, all of whom are specifically designed to be skilled and agile in a fight, but also would not be ‘tied’ to anyone back home. The US Army has apparently been researching this possibility and, according to Simon Conway (a novelist who had access to the Pentagon’s defence research plans), these soldiers would not need to eat or sleep and would be able to “re-grow limbs that were destroyed by enemy fire” [Gucciardi, 2012]. This information, having come from a novelist who may be prone to exaggeration, may not be reliable, but there is the possibility that such research may happen in the future, even if it hasn’t been conducted so far. These “Super Soldiers” [Gayle, 2012] sound like a good idea, because it would prevent our friends and family having to give up their lives to save our country, but many people have reservations about this concept. Some people fear (perhaps not irrationally) that these soldiers could turn against us and end up destroying the whole of humanity. Another argument is that, no matter how they were created, they (unlike Saruman’s orcs) are still human beings and do not deserve to be sent off to war with no choice. A problem that may be encountered in the future is parents choosing attributes that may hinder their child, or at least not benefit them. Currently, parents can name their child almost anything, but that is the only ‘damage’ they can do and names can easily be changed. What would happen to society if the kinds of people who name their child “Blanket” were allowed to choose what their child looks like? Surely that wouldn’t be fair to the child? 22 Currently, the stereotypical designer baby (which has its eye colour, hair colour, height and attributes such as athleticism chosen for it by its parents) cannot be made by altering the genetic makeup. This is because these characteristics are hard to change as they are affected by many genes and manipulating all of these genes is beyond our current scientific capabilities [D. Simmons, 2008]. However, considering recent scientific advancements, there is every possibility that this may happen in the future; people may be able to choose their baby’s appearance. But there are huge moral implications that go along with this; is it right to choose? Surely you should love your child regardless of their appearance or attributes? But if you decide to leave everything to chance, your child will be ‘normal’, while most of the people around them will be what their parents perceive to be ‘perfect’, so they may feel left out. 23 Conclusion According to the Oxford Dictionary, a designer baby is “a baby whose genetic makeup has been artificially selected by genetic engineering... to ensure the presence or absence of particular genes or characteristics” [Oxford Dictionary, 2010]. While today’s technological advances did not exist during Hitler’s dictatorship or at the height of the American eugenics movement, one could still consider these events to have caused the creation of designer babies. No actual genes were altered, but the gene pool was limited by the sterilisation/deaths of certain groups in society, thus essentially designing a race through elimination of undesired characteristics. There are two different types of eugenics; positive and negative. Hitler’s aims mainly involved negative eugenics; he aimed to remove ‘bad’ genes from the gene pool. This is normally perceived to be inhumane, but positive eugenics could be seen in a good light because it includes simply encouraging well-bred families to produce more children; it does not have to involve killing anyone. For this reason, I do not think that eugenics is completely immoral; ‘improving’ society may be a good idea because it may help it to function better, but I personally do not believe that it could be achieved without escalation into other things due to the majority of humans not being able to possess power without abusing it. The ethical arguments surrounding current genetic engineering are completely different to those surrounding Hitler’s Aryan race, but should they be? The public were made to believe that the Nazis and the American government were implementing eugenic laws because it was in the best interest of the people and was a necessary step forward in science. It is mainly for these reasons that the public view them in a negative light, because we no longer perceive the ideas to be a benefit to society. This is a valid argument, but our current scientific advances may be viewed in exactly the same way in another 70 years. I do not believe that we can completely rule out genetic engineering, but equally we 24 should be cautious about advances that do not completely agree with public morals. It would be quite easy to change your morals based on what someone you trust says, but that would lead society to the problem that faced the German and American societies in the 20th Century. In my opinion, designer babies should be used to reduce suffering by removing genetic diseases. We use medical drugs to reduce suffering, which isn’t much different to removing disease before birth. Obviously changing someone’s genetic makeup is different to giving them treatment, but I think the same kind of arguments can be used for both. It would also save money due to not having to support people with disabilities through treatments. However, I don’t think that allowing parents to choose the appearance of their child is a good way forward for society because parents should love their child regardless of their appearance. It also introduces an unrealistic expectation of perfection, as well as a consumerist attitude towards children, which would completely change the dynamics of family life and possibly even the functionality of society. 25 Evaluation I thoroughly enjoyed writing this project because it allowed me to delve into a subject that was unrelated to my A-Level subjects, whilst developing my scientific knowledge and essay-writing skills. Writing this project has taught me skills in time management, organisation, referencing and researching. Time management was a skill that I quickly discovered I needed to improve because this was the first big project that I had a deadline for, so I had no previous experience of planning and managing my time. All of these skills will be useful later in life, especially for university. I have learnt about how important it is to have completed all of your research and put it into a logical order before thinking about writing the essay. I tried to start writing before I had ordered my information, which made it very difficult and meant that I had to go back and order it before continuing. If I was to do this project again, I would organise my sources as I found them and evaluate their reliability at that point, rather than having to go back and evaluate at the end. I would also make sure I had a complete understanding of everything before writing because I occasionally found myself writing about something that I didn’t fully understand and had to go back to the source to comprehend the process before being able to discuss it. My project could be extended by looking further into areas such as the effect of the popularisation of eugenics on the rest of the world. For example, I had discovered that there were archives for the British Eugenics Society in the Wellcome Centre, but did not have time or space to include anything about them. This information was also not completely important to the title and to Hitler’s actions. The impression on modern society as a result of Hitler and the eugenics movements could also be discussed, for example groups in society who currently have similar views to Hitler and the Nazis, such as the Danish People’s Party and the British 26 National Party. The political stance and laws in different countries surrounding genetic engineering and designer babies and their effect on public opinion could also be discussed. 27 Bibliography • • • • • • • • • • • • • Alzheimer’s Society (2012) Genetics and Dementia [Internet] London, Alzheimer’s Society. Available from: <http://www.alzheimers.org.uk/site/scripts/documents_info.php?documentID=168> [Accessed 5 November 2012]. American Philosophical Society (1930) Letter from Field Secretary, American Eugenics Association to Fair Associations asking education exhibit space [Internet], USA, Eugenics Archive. 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