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ADC Peptide Linkers

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 ADC Peptide Linkers
CAT#
Product Name
P d tN
Chemical Structure
Ch i l St t
L1001‐1
Val‐Cit‐PAB
98%
L1001‐2
Fmoc‐Val‐Cit‐PAB
98%
N3-PEG(3-6)
N
H
L1001‐3
N3‐PEG(3‐6)‐Val‐Cit‐PAB
O
H
N
Purity
P it
OH
N
H
O
95%
NH
O
NH2-PEG(3-6)
N
H
L1001‐4
NH2‐PEG(3‐6)‐Val‐Cit‐PAB
H
N
NH2
O
OH
N
H
O
95%
NH
O
Fmoc-NH-PEG(3-6)
N
H
L1001‐5
Fmoc‐NH‐PEG(3‐6)‐Val‐Cit‐PAB
H
N
NH2
O
OH
N
H
O
95%
NH
O
Boc-NH-PEG(3-6)
N
H
L1001‐6
Boc‐NH‐PEG(3‐6)‐Val‐Cit‐PAB
H
N
NH2
O
OH
N
H
O
95%
NH
O
NH2
Trt-NH-PEG(3-6)
N
H
L1001‐7
O
H
N
N
H
O
Trt‐NH‐PEG(3‐6)‐Val‐Cit‐PAB
OH
98%
NH
O
NH2
L1002‐1
Fmoc‐Val‐Cit‐PAB‐PNP
98%
L1002‐2
MC‐Val‐Cit‐PAB‐PNP
98%
NO2
O
O
N3-PEG(3-6)
L1002‐3
L1002
3
NH
NH
N3‐PEG(3‐6)‐Val‐Cit‐PAB‐PNP
N3
PEG(3 6) Val Cit PAB PNP
O
O
NH
98%
O
NH
O
NH2
NO2
O
O
NH2-PEG(3-6)
L1002‐4
NH2‐PEG(3‐6)‐Val‐Cit‐PAB‐PNP
NH
NH
O
O
NH
95%
O
NH
O
NH2
NO2
O
O
Fmoc-NH-PEG(3-6)
L1002‐5
NH
NH
Fmoc‐NH‐PEG(3‐6)‐Val‐Cit‐PAB‐PNP
O
O
NH
95%
O
NH
O
NH2
NO2
O
O
Boc-NH-PEG(3-6)
L1002‐6
Boc‐NH‐PEG(3‐6)‐Val‐Cit‐PAB‐PNP
NH
NH
O
NH
95%
O
NH
O
O
NH2
NO2
O
O
Trt-NH-PEG(3-6)
L1002‐7
NH
NH
Trt‐NH‐PEG(3‐6)‐Val‐Cit‐PAB‐PNP
O
O
NH
95%
O
NH
O
NH2
L1003
Phe‐Lys (Trt)‐ PAB
98%
L1004‐1
Fmoc‐Phe‐Lys (Trt)‐ PAB‐PNP
98%
L1004‐2
L1004
2
MC
MC‐Phe‐Lys (Trt)‐ PAB‐PNP
Phe Lys (Trt) PAB PNP
98%
NO2
O
L1004‐3
N3‐PEG(3‐6)‐Phe‐Lys (Trt)‐ PAB‐PNP
N
H
O
O
H
N
N3-PEG(3-6)
O
95%
N
H
O
HN
Trt
NO2
O
NH2-PEG(3-6)
L1004‐4
NH2‐PEG(3‐6)‐Phe‐Lys (Trt)‐ PAB‐PNP
N
H
O
O
H
N
O
N
H
O
95%
HN
Trt
NO2
O
Fmoc-NH-PEG(3-6)
L1004‐5
Fmoc‐NH‐PEG(3‐6)‐Phe‐Lys (Trt)‐ PAB‐PNP
N
H
H
N
O
O
O
N
H
O
95%
HN
Trt
NO2
O
L1004‐6
N
H
Boc‐NH‐PEG(3‐6)‐Phe‐Lys (Trt)‐ PAB‐PNP
O
O
H
N
Boc-NH-PEG(3-6)
O
N
H
O
95%
HN
Trt
NO2
O
L1004‐7
N
H
Trt‐NH‐PEG(3‐6)‐Phe‐Lys (Trt)‐ PAB‐PNP
O
O
H
N
Trt-NH-PEG(3-6)
O
N
H
O
95%
HN
Trt
L1005
Ala‐Ala‐Asn‐PAB
95%
L1006‐1
L1006
1
Fmoc
Fmoc‐Ala‐Ala‐Asn‐PAB‐PNP
Ala Ala Asn PAB PNP
95%
NO2
O
L1006‐2
N3‐PEG(3‐6)‐Ala‐Ala‐Asn‐PAB‐PNP
N3-PEG(3-6)
O
H
N
N
H
O
O
H
N
O
95%
N
H
O
O
NH2
NO2
O
L1006‐3
NH2‐PEG(3‐6)‐Ala‐Ala‐Asn‐PAB‐PNP
O
H
N
N
H
NH2-PEG(3-6)
O
O
H
N
O
95%
N
H
O
O
NH2
NO2
O
L1006‐4
H
N
Fmoc‐NH‐PEG(3‐6)‐Ala‐Ala‐Asn‐PAB‐PNP
Fmoc-NH-PEG(3-6)
O
N
H
H
N
O
O
O
O
95%
N
H
O
NH2
NO2
O
L1006‐5
Boc‐NH‐PEG(3‐6)‐Ala‐Ala‐Asn‐PAB‐PNP
Boc-NH-PEG(3-6)
H
N
O
N
H
H
N
O
O
O
95%
N
H
O
O
NH2
NO2
O
L1006‐6
Trt‐NH‐PEG(3‐6)‐Ala‐Ala‐Asn‐PAB‐PNP
Trt-NH-PEG(3-6)
H
N
O
N
H
H
N
O
O
O
N
H
O
NH2
O
95%
ADC Bi‐Functional Linker
CAT#
Product Name
Chemical Structure
Purity
L1010
Mal‐HA‐Osu
95%
L1011
Mal‐Di‐EG‐Osu
95%
L1012
Mal‐Tri‐EG‐Osu
95%
L1013
Mal‐Tetra‐EG‐Osu
95%
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