MEMBER'S COPY DECEMBER 1992 VOL 67 NO 12 ARCHIVES OF DISEASE IN CHILDHOOD The Journal of the British Paediatric Association Annotations Original articles 1417 The place of computed tomography and lumbar puncture in suspected bacterial meningitis David H Mellor 1420 Sleep problems Gregory Stores 1421 Routine discharge examination of babies-is it necessary? P H T Cartlidge 1423 Do maternal and intrauterine factors influence blood pressure in childhood? P H Whincup, D G Cook, 0 Papacosta 1430 Management and outcome of severe head injuries in the Trent region 1985-90 A C Elias-Jones, J A G Punt, A E Turnbull, et al 1436 Long term effects of periconceptional multivitamin supplements for prevention of neural tube defects: a seven to 10 year follow up MonicaHolmes-Siedle,3JenniferDennis, R H Lindenbaum, et al 1442 A randomised trial of low dose folic acid to prevent neural tube defects Peadar N Kirke, Leslie E Daly, J Harold Elwood for the Irish Vitamin Study Group 1447 Immunohistochemical features of the portal tract mononuclear cell infiltrate in chronic aggressive hepatitis Giorgio Senaldi, Bernard Portmann, Alex P Mowat, et al 1454 Bronchial responsiveness and lung function in infants with lower respiratory tract illness over the first six months of life Jane R Clarke, Amanda Reese, Michael Silvernan 1459 Association of perinatal events, epilepsy, and central nervous system trauma with juvenile delinquency Paula Rantakallio, Markku Koiranen, Jyrki Mottonen 1462 Urinary protein/creatinine index in follow up of patients with Wilms' tumour after nephrectomy C Mpofu, J R Mann 1467 Teachers' perceptions of epilepsy M J Bannon, C Wildig, P WJones 1472 Growth hormone deficiency during puberty reduces adult bone mineral density S L Hyer, D A Rodin,J H Tobias, et al 1475 Hazards of parenteral treatment: do particles count? J W L Puntis, K M Wilkins, P A Ball, et al 1478 Sinusitis-induced subdural empyema Ruth Skelton, Wirginia Maixner, David Isaacs 1481 Familial pancreatic enzyme insufficiency G Owen, P WBuss, H R Jenkins, et al 1483 Thrombolysis with low dose tissue plasminogen activator E Doyle, J Britto, J Freeman, et al 1484 Fatal encephalitis/encephalopathy in primary human herpesvirus-6 infection YAsano, T Yoshikawa, YKajita, et al 1486 Recovery of protein from urine specimens collected in cotton wool G C Smith, C M Taylor Types of psychiatric treatment Statistics from the inside Current topics Personal practice Referees and staff Letters to the editor Index Archivist 1488 (11) Drug treatment Michael Prendergast 1495 8. Size, power, and confidence MJ R Healy 1498 The ethics of cardiopulmonary resuscitation. I. Background to decision making J M Davies, B M Reynolds 1502 The ethics of cardiopulmonary resuscitation. II. Medical logistics and the potential for good response J M Davies, B M Reynolds 1506 Suitability of the paediatric setting for hospitalised adolescents M L Gillies, WLI Pary-Jones 1510 Factitious illness: recognition and management D M Eminson, RJ Postlethwaite 1517 1519 1521 1441, 1446 BMJ PUBLISHING GROUP VOLUME 67 * CONTENTS No 1 JANUARY 1992 1 10 12 15 20 25 31 36 41 44 48 53 57 62 63 65 69 72 74 FETAL AND NEONATAL EDITION Original articles Catabolic effect of dexamethasone in the preterm baby K G Brownlee, P C Ng, M Jf Henderson, et al Dexamethasone increases plasma amino acid concentrations in bronchopulmonary dysplasia A F Williams, MJones Dexamethasone treatment during ventilator dependency: possible life threatening gastrointestinal complications Elizabeth A O'Neil, WalterJ Chwals, Michael D O'Shea, et al Low dose intraventricular fibrinolytic treatment to prevent posthaemorrhagic hydrocephalus A Whitelaw, R P A Rivers, L Creighton, et al Symmetrical thalamic lesions in infants M Eicke,j Briner, U Willi, et al Evaluation of techniques for delivery of steroids to lungs to neonates using a rabbit model Christopher O'Callaghan, John Hardy,3Julie Stammers, et al Delivery of therapeutic aerosols to intubated babies Jonathan Grigg, Shmuel Arnon, Tracey Jones, et al Treatment of severe persistent pulmonary hypertension of the newborn with magnesium sulphate YousefK Abu-Osba, Omar Galal, Khader Manasra, et al Measurement of plasma volume in neonates M YAnthony, S R Goodall, M Papouli, et al IgG subclasses compared in maternal and cord serum and breast milk A Gasparoni, A Avanzini, F Ravagni Probiser, et al Reduced use of surface cultures for suspected neonatal sepsis and surveillance S R M Dobson, D Isaacs, A R Wilkinson, et al Candida strains from neonates in a special care baby unit A M Sharp, F C Odds, E G V Evans Enterobacteriaceae and neonatal necrotising enterocolitis M R Millar, P MacKay, M Levene, et al Gentamicin: influence of dosing on pharmacokinetics, nephrotoxicity, and antibacterial activity H Skopnik, R Wallraf, B Nies, et al Cyclical fluctuations in cerebral blood volume L N Livera, YA B D Wickramasinghe, S A Spencer, et a! Neonatal renal candidal bezoar V K Rehan, D C Davidson Obstetrics for paediatricians Rhesus haemolytic disease MartinJ7 Whittle Current practice Respiratory support using patient triggered ventilation in the neonatal period A Greenough, A D Milner Perinatal lessons from the past Dr William Cadogan (1711-1797) of Bristol and the management of infants PM Dunn Book reviews No 1 JANUARY 1992 Annotation 75 Psoriasis in childhood 3rulian Verbov Original articles 77 Co-morbidity associated with fabricated illness (Munchausen syndrome by proxy) C N Bools, B A Neale, S R Meadow 80 Comparison of BCG vaccination at birth and at third month of life Ibrahim Ildirim, Nihat Sapan, Bulent Cavusoglu 83 Conditions accounting for substantial time spent in hospital in children aged 1-14 years Jane Henderson, MichaelJ7 Goldacre, Jennie M Fairweather, et al 87 Congenital hypothyroidism detected by neonatal screening: relationship between biochemical severity and early clinical features D B Grant, I Smith, P W Fuggle, et al 91 Relationship between urinary and serum growth hormone and pubertal status E C Crowne, W H B Wallace, S M Shalet, et al 96 Limited joint mobility in subjects with insulin dependent diabetes mellitus: relationship with eye and kidney complications Satish K Garg, H Peter Chase, Guillermo Marshall, et al 100 Failure to prevent nicotine addiction in young people with diabetes E A Masson, I A MacFarlane, CJ Priestley, et al 103 Do doctors recognise eating disorders in children? RachelJ Bryant-Waugh, Bryan D Lask, Rosamund L Shafran, et al 106 Trial of intensive compared with weekly speech therapy in preschool children J7ean Barratt, Peter Littlejohns, J'ulie Thompson 109 Home parenteral nutrition in chronic intestinal failure W M Bisset, P Stapleford, S Long, et al 115 A biotinidase Km variant causing late onset bilateral oral neuropathy V Th Ramaekers, TM Suormala, M Brab, et al 120 Beta glucuronidase and hyperbilirubinaemia in breast fed infants of diabetic mothers L Sirota, M Ferrera, N Lerer, et al 122 Axillary and rectal temperature measurements in infants CJ Morley, P H Hewson, A J Thornton, et al 126 Streptococcus associated toxic shock C Torres-Martinez, D Mehta, A Butt, et al 131 Implantable intravenous access device L L Goldsworthv, H M Daly 132 Paediatric psychotherapy: a service in a general outpatient clinic Susan Vas Dias, Sheila A McKenzie 134 Coeliac disease and lymphangiectasia Vojislav N Perisic, George Kokai 136 Positive end expiratory pressure via a portable system in thoracic dystrophy S Edees, A Moulden, RJ Winter Current topic 138 HIV infection in children D Gibb, M L Newell Regular review 142 Medium chain acyl-CoA dehydrogenase deficiency E H Touma, C Charpentier Personal practice 146 Lower oesophageal pH monitoring-a useful clinical tool David M Tappin, Caroline King, James Y Paton Statistics from the inside 149 3. Estimation MJ7 R Healy 151 Letters to the editor 154 Book reviews 155 Meeting in 1992 156 Instructions to authors No 2 FEBRUARY 1992 Annotations 157 Antibiotic choices for meningitis beyond the neonatal period Nj Klein, R S Hevderman, M Levin 159 Fibreoptic bronchoscopy in infants de Blic, P Scheinmann Original articles 162 Fourteen cases of imposed upper airway obstruction M P Samuels, W McClaughlin, R RJacobson, et al 171 Combined effect of infection and heavy wrapping on the risk of sudden unexpected infant death Ruth Gilbert, Peter Rudd, PJeremy Berry, et al 178 A clinical study of Noonan syndrome M Sharland, M Burch, WM McKenna, et al 184 Desmopressin for bed wetting: length of treatment, vasopressin secretion, and response J H C Evans, S R Meadow 189 Twin peaks, extramarital conceptions, and virgin births: is there a connection? M Murphy, V Seagroatt 192 Controlled study of Pseudomonas cepacia and Pseudomonas maltophilia in cystic fibrosis G Gladman, PI Connor, R F Williams, et al 196 Prospective evaluation of the Paediatric Risk of Mortality (PRISM) score Ganapathy Balakrishnan, Tom Aitchison, David Hallworth, et al 201 Surgical treatment of hyperinsulinaemic hypoglycaemia L Spitz, R K Bhargava, D B Grant, et al 206 Consultation time, workload, and problems for audit in outpatient clinics James W Partridge 211 Clinical review of idiopathic versus hepatitis B surface antigen related forms of membranous glomerulonephritis Seza Ozen, Umit Saatci, Aysin Bakkaloglu, et al 214 Inhaled frusemide against cold air induced bronchoconstriction in asthmatic children J Seidenberg,J Dehning, H von der Hardt 218 Persistent gastrointestinal symptoms after correction of malrotation S P Devane, R Coombes, V V Smith, et al 222 Rehabilitation and outcome after severe head injury R Scott-Jupp, N Marlow, N Seddon, et al 227 Post-traumatic tremor in head injured children S L77ohnson, D MB Hall 229 Energy intake and basal metabolic rate during maintenance chemotherapy S A Bond, A M Han, S A Wootton, et al 233 Fever associated with teething LJ7aber, IJ Cohen, A Mor 234 Growth patterns after surgery for virilising adrenocortical adenoma A TSalt, M O Savage, D B Grant Types of psychiatric treatment 237 Types of psychiatric treatment: overview PhilipJ Graham Special report 240 Asthma: a follow up statement from an international paediatric asthma consensus group Statistics from the inside 249 4. Sampling distributions MJ R Healy Looking back 251 Decline and fall of the tubercle bacillus: the Newcastle story 1882-1988 FJ WMiller, Mary D Thompson 256 Letters to the editor No 3 MARCH 1992 Annotations 257 The urgency of immersions John Pearn 258 Reactive amyloidosis Joel David, Patricia Woo Original articles 262 Congenital retinal dystrophies: a study of early cognitive and visual development Marilyn M Black, Patricia M Sonksen 266 Memory after treatment for acute lymphoblastic leukaemia J Rodgers, P G Britton, R G Morris, et al 269 What consistency of food is best for children with cerebral palsy who cannot chew? R D Croft 272 Gut regulatory peptides and intestinal permeability in acute infantile gastroenteritis G R Lawson, R Nelson, M F Laker, et al 277 Increased plasma tumour necrosis factor-( concentration in atopic dermatitis S Sumimoto, M Kawai, Y Kasaiima, et al 280 Interleukin-2 production of lymphocytes in food sensitive atopic dermatitis Hiroatsu Agata, Naomi Kondo, Osamu Fukutomi, et al 285 Inhaled budesonide for chronic wheezing under 18 months of age V Noble, N R Ruggins, M L Everard, et al 289 Bronchodilators for treatment of mild bronchiolitis: a factorial randomised trial Elaine E L Wang, Ruth Milner, Upton Allen, et al 294 The intensive care unit in paediatric oncology D Heney, IJ Lewis, L Lockwood, et al 299 Pulse oximetry reference values at high altitude Juan Manuel Lozano, Olga Rebeca Duque, Tatiana Buitrago, et al 302 Narcolepsy M R Allsopp, Z Zaiwalla 307 Postnatal encephaloclastic porencephaly-a new lesion? J H Cross, CJI Harrison, P R Preston, et al 312 Effect of positioning on the breathing pattern of preterm infants Ruth Heimler,3Jeanne Langlois,.DanielJ Hodel, et al 315 An indirect calorimetry system for ventilator dependent very low birthweight infants J S Forsyth, Anna Crighton 320 Positive end expiratory pressure in acute and chronic respiratory distress A Greenough, V Chan, M F Hird 324 Randomised trial of nutrition for preterm infants after discharge A Lucas, NJ Bishop, FJ King, et al 328 Varicella zoster virus DNA in throat swabs of vaccines T Ozaki, H Miwata, Y Asano, et al 330 Advantages of working in the developing world CJ C Williams Commentary-DavidMorley 332 Measuring compliance with inhaled medication in asthma J A P Coutts, N A Gibson, J Y Paton Contemporary history 334 A girl in my arms: a story of a paediatrician from Vukovar Branka Sipek Types of psychiatric treatment 336 (2) Individual psychotherapy J7udith Trowell Personal practice 340 Management of chronic constipation Graham S Clavden Current topic 345 The provision of safe surgery for children John D Atwell, Paul M Spargo 350 Letters to the editor 353 Spring books FETAL AND NEONATAL EDITION No 4 APRIL 1992 Original articles 357 Patterns of metabolic adaptation for preterm and term infants in the first neonatal week 7 M Hawdon, M P Ward Platt, A Avnsley-Green 366 Pulmonary and systemic arterial pressure in hyaline membrane disease Jonathan R Skinner, RichardJ7 Boys, Stewart Hunter, et al 374 Central venous pressure in the ventilated neonate 7onathan R Skinner, David WA Milligan, Stewart Hunter, et al 378 Phosphatidylcholine composition of endotracheal tube aspirates M R Ashton, A D Postle, M A Hall, et al 383 Turnover of exogenous artificial surfactant M R Ashton, A D Postle, M A Hall, et al 388 Plasma hypoxanthine: a marker for hypoxic-ischaemic induced periventricular leucomalacia? G A B Russell, GJeffers, R W I Cooke 393 Somatosensory evoked potentials and outcome in perinatal asphyxia N A Gibson, M Graham, M I Levene 399 Blood leucocyte count in the human fetus N P Davies, A G S Buggins, RJ M Snijders, et al 404 Fetal leucocyte count in rhesus disease N P Davies, A G S Buggins, R M Snijders, et al 407 Plethysmographic validation of near infrared spectroscopic monitoring of cerebral blood volume YA B D Wickramasinghe, L N Livera, S A Spencer, et al 412 Postnatal evolution of slow variability in cerebral blood flow velocity Heather Coughtrey, 7anet M Rennie, David H Evans 416 Intravenous aminophylline and cerebral blood flow in preterm infants Maura McDonnell, N K Ives, P L Hope 419 Upper airway patency during apnoea of prematurity CJ Upton, A D Milner, G M Stokes 425 Caffeine or theophylline for neonatal apnoea? J E M Scanlon, K C Chin, M E I Morgan, et al 429 Randomised trial of continuous nasogastric, bolus nasogastric, and transpyloric feeding in infants of birth weight under 1400 g P D Macdonald, C H Skeoch, H Carse, et al 432 Risk factors for necrotising enterocolitis: the influence of gestational age PhilipJ Beeby, Heather3Jeffery 436 Capillary plasma elastase (xi-proteinase inhibitor in infected and non-infected neonates R L Rodwell, KM Taylor, D I Tudehope, et al 440 Breathing pattern abnormalities in full term asphyxiated newborn infants P Sasidharan 443 Intracardiac thrombus formation with rapidly progressive heart failure in the neonate: treatment with tissue type plasminogen activator B Van Overmeire, PJ Van Reempts, KJ Van Acker 446 Respiratory timing in intubated neonates with respiratory distress syndrome M South, CJ Morley 448 Intraventricular haemorrhage after aspiration of ventricular reservoirs N E Moghal, M W Quinn, M I Levene, et al Perinatal biology 450 Prenatal treatment with thyrotrophin releasing hormone to prevent neonatal respiratory distress Francis de Zegher, Bernard Spitz, Hugh Devlieger Regular review 455 On the horizon: neonatal lung transplantation N ScottAdzick Current topics 458 Neonatal nurse practitioners-a view from perfidious Albion? M A Hall, S L Smith,J EJackson, et al Commentary-L O'Hagan 463 Vascular compromise in newborn infants D T Gault Commentary-M L Chiswick Perinatal lessons from the past 468 Scevole de Ste Marthe of France (1536-1623) and The Paedotrophia PM Dunn 470 Letters to the editor No 4 APRIL 1992 Annotation 473 Neonatal BCG immunisation Antonia Clarke, Peter Rudd Original articles 475 Immunogenicity and safety of PRP-T conjugate vaccine given according to the British accelerated immunisation schedule R Booy, S A Taylor, S R M Dobson, et al 479 Raised serum soluble interleukin-2 receptor concentrations in cystic fibrosis patients with and without evidence of lung disease ElifDagli,'illA Warner, CR Besley, et al 482 Respiratory status and allergy after bronchiolitis M Murray, M S C Webb, C O'Callaghan, et al 488 Bronchial responsiveness in an area of air pollution resulting from wire reclamation J Y Wang, T R Hsiue, H I Chen 491 Atopy, bronchial responsiveness, and symptoms in wheezy 3 year olds Nicola M Wilson, Stephen B Phagoo, MichaelSilverman 496 Enhanced allergic sensitisation related to parental smoking R Ronchetti, E Bonci, R Cutrera, et at 501 Middle aortic syndrome: clinical and radiological findings A Sumboonnanonda, B L Robinson, WM W Gedroyc, et al 506 Vesicoureteric reflux and renal scars in asymptomatic siblings of children with reflux Rajko B Kenda, Jurij F Fettich 509 Vulvovaginitis: causes and management A M Pierce, C A Hart 513 Growth in patients with isolated gonadotrophin deficiency Z Dickerman, A Cohen, Z Laron 517 Fetal haemoglobin and early manifestations of homozygous sickle cell disease K Bailey,J S Morris, P Thomas, et al 521 Sinus histiocytosis with massive lymphadenopathy David K Stones, Charmaine Havenga 524 T cell immunodeficiency in dyskeratosis congenita B W Lee, H K Yap, T C Quah, et al 527 Anal abnormalities in childhood myotonic dystrophy-a possible source of confusion in child sexual abuse W Reardon, H E Hughes, S H Green, et al 529 Sonographic detection of the lead point in intussusception M D Stringer, S NJ Capps, S M Pablot 530 Tuberculin skin reactivity four years after neonatal BCG vaccination L P Ormerod,J M Garnett 531 Association of high fever and short bacterial excretion after salmonellosis A Sahib El-Radhi, Timo Rostila, Timo Vesikari Statistics from the inside 533 5. Data structures MJ R Healy Types of psychiatric treatment 536 (3) Counselling parents in child behaviour therapy R McAuley Practice abroad 543 Paediatric illness in Hong Kong and Britain D P Davies Personal practices 550 Chronic fatigue syndrome: a joint paediatric-psychiatric approach Margaret I Vereker 556 Human milk banking at Sorrento Maternity Hospital, Birmingham S E Balmer, B A Wharton Current topic 560 Paediatrics in the accident and emergency department B M Phillips, Controversy-a review of a report 565 Physical signs of sexual abuse in children Margaret A Lvnch 567 Letters to the editor No 5 MAY 1992 Annotations 569 Diabetes in puberty D B Dunger 571 'Personal child health records' held by parents 572 Medulloblastoma Clifford C Bailev Aidan Macfarlane WJ Robson 574 580 586 592 595 600 603 608 613 618 622 625 628 632 636 640 641 643 649 654 657 662 No 6 JUNE 1992 Original articles Profile of bronchial responsiveness in children with respiratory symptoms J B Clough,3t D Williams, S T Holgate Drug delivery from holding chambers with attached facemask Mark L Everard, Andrew R Clark, Anthony D Milner Drug delivery from jet nebulisers Mark L Everard, Andrew R Clark, Anthony D Milner Role of infection in the middle lobe syndrome in asthma Chaim Springer, Avraham Avital, Natan Noviski, et al HIV-I infection and perinatal mortality in Zimbabwe C GA Aiken Deaths at home and in hospital in Zimbabwe B H M Wolf, M O Ikeogu Intensive enteral feeding in advanced cirrhosis: reversal of malnutrition without precipitation of hepatic encephalopathy C PJ Charlton, E Buchanan, C E Holden, et al Using steatocrit to determine optimal fat content in modular feeds M 0 Rawashdeh, D R Lloyd, J W L Puntis, et al Electrogastrography in non-ulcer dyspepsia S Cucchiara, G Riezzo, R Minella, et al Gaviscon and Carobel compared with cisapride in gastro-oesophageal reflux P Greally, FJ Hampton, UM MacFadyen, et al Should audio recordings of outpatient consultations be presented to patients? George Rylance Chloroquine in idiopathic pulmonary haemosiderosis Andrew Bush, Mary N Sheppard,J7 0 Warner Abnormal serum IgG subclass pattern in Down's syndrome G Anneren, C G M Magnusson, G Lilja, et al Height and body proportions in child abuse J K H Wales, S M Herber, L S Taitz Home blood pressure monitoring in diabetes Caroline Gompels, Denis Savage Incidence of normal micturition in myelomeningocele patients I Reiner, MJones, S Donnell, et al Treatment of refractory ulcerative oesophagitis with omeprazole A M Dalzell, J WSearle, M K Patrick Types of psychiatric treatment (4) Change the family, change the child? Christopher Dare Current topics Intravenous volume replacement: which fluid and why? Lucinda Huskisson The autonomic nervous system-a role in sudden infant death syndrome T G Matthews Regular review Biological role of lactoferrin Lourdes Sanchez, Miguel Calvo, Jeremy H Brock Letters to the editor Annotations 669 Paediatric cochlear implantation Kevin P Gibbin 671 Detection of minimal residual disease in leukaemia Fay E Katz 673 Stressful life events and childhood illness Ian M Goodyer Original articles 675 The Scottish low birthweight study: I. Survival, growth, neuromotor and sensory impairment The Scottish Low Birthweight Study Group 682 The Scottish low birthweight study: II. Language attainment, cognitive status, and behavioural problems The Scottish Low Birthweight Study Group 687 Impaired motor function (clumsiness) in 5 year old children: correlation with neonatal ultrasound scans Makolm Levene, Sheila Dowling, Margaret Graham, et al 691 Postdischarge formula consumption in infants born preterm A Lucas, F King, N B Bishop 693 Computed tomography findings in partial seizures A M B Minford, W I Forsythe 697 Difficult and unlikeable parents Roy Meadow 703 Asthma, inhaled corticosteroid treatment, and growth Titus K Ninan, George Russell 706 Mononuclear cells subsets and coronary artery lesions in Kawasaki disease Susumu Furukawa, Tomoyo Matsubara, Keijiro Yabuta 709 Tartrazine in atopic eczema J Devlin, TJ David 712 Dysmorphic features in offspring of alcoholic mothers I Autti-Ramo, E Gaily, M-L Granstrom 717 Frontoethmoidal meningoencephalocele: a common and severe congenital abnormality in South East Asia Christopher G M Richards 720 Early diagnosis and management of 5 (x-reductase deficiency I Odame, M D C Donaldson, A M Wallace, et al 724 Salivary IgA antigliadin antibody as a marker for coeliac disease V Hakeem, R Fifield, H F Al-Bayaty, et al 728 Late diagnosis of cryptorchidism: a failure of medical screening? A Sarmah 731 Family characteristics and insulin dependent diabetes M Alison Metcalfe, J David Baum 737 IgG antibodies in early Pseudomonas aeruginosa infection in cystic fibrosis S M Cordon,3t S Elborn, RJ Rayner, et al Controversy 741 The value of proximal small intestinal biopsy in the differential diagnosis of chronic diarrhoea A G Thomas, A D Phillips,JI A Walker-Smith Commentary-R A F Bell, H Marcovitch Types of psychiatric treatment 745 (5) Dealing with the courts and parenting breakdown Claire Sturge Chalienges 751 Child health and paediatric care in Spain: where are we going? Angel Ballabriga Statistics from the inside 757 6. Data structures (continued) M R Healy 760 Letters to the editor 761 Book reviews 763 Instructions to authors Archivist 723, 740, 759, 764 No 7 JULY 1992 765 767 770 775 779 FETAL AND NEONATAL EDITION Annotations Do we need an Apgar score? Neil Marlow Metabolic acidosis in newborn infants J HI Walter Original articles Fetal abnormality: an audit of its recognition and management-Northern Regional Survey Steering Group Potential impact of population screening for prenatal diagnosis of congenital heart disease Seamus Cullen, Gurleen K Sharland, Lindsey D Allan, et al Cytomegalovirus prevalence in pregnant women: the influence of parity Pat A Tookey, Anthony E Ades, Catherine S Peckham 784 Skin temperature and heart rate rhythms in infants of extreme prematurity S W D'Souza, S Tenreiro, D Minors, et al 789 Prediction of impaired metabolic adaptation by antenatal Doppler studies in small for gestational age fetuses J M Hawdon, M P Ward Platt, S McPhail, et al 793 Superior mesenteric artery blood flow velocity in necrotising enterocolitis S T Kempley, H R Gamsu 797 Development of cutaneous microflora in premature neonates N Keyworth, M R Millar, K T Holland 802 Complement activation in neonatal infection M Peakman, G Senaldi, G Liossis, et al 808 Receiver operating characteristic curves for comparison of serial neutrophil band forms and C reactive protein in neonates at risk of infection G A B Russell, A Smyth, R W I Cooke 813 Neutrophil chemotaxis and adhesion in preterm babies R Carr, D Pumford, J M Davies 818 Serum erythropoietin concentrations of symptomatic infants during the anaemia of prematurity Jill Meyer, Alan Sive, PeterJacobs 822 UK experience in neonatal extracorporeal membrane oxygenation GA Pearson, DJ Field, R K Firmin, et al 826 New aerosol delivery system for neonatal ventilator circuits Mark L Everard, Julie Stammers, John G Hardy, et al 831 Episodic bradycardia in preterm infants C J Upton, A D Milner, G M Stokes 835 Cerebrovascular carbon dioxide reactivity and failure of autoregulation in preterm infants Alan C Fenton, Kent L Woods, David H Evans, et al 840 Traumatic neonatal intracranial bleeding and stroke Paul Govaert, Piet Vanhaesabrouck, Claudine de Praeter 846 Athetoid cerebral palsy with cysts in the putamen after hypoxic-ischaemic encephalopathy M A Rutherford, J M Pennock, D M Murdoch-Eaton, et al 851 Regional cerebral blood blow velocity changes after indomethacin infusion in preterm infants N C Austin, P W Pairaudeau, TK Hames, et al 855 Randomised trial of umbilical arterial catheter position: Doppler ultrasound findings S TKempley, HR Gamsu Special reports 860 Screening for retinopathy of prematurity Alistair R Fielder, Malcolm I Levene 868 Report of working group of the British Association of Perinatal Medicine and Neonatal Nurses Association in categories of babies requiring neonatal care Personal practice 870 Use of sedatives and muscle relaxants in newborn babies receiving mechanical ventilation Malcolm I Levene, Michael W Quinn Current topic 874 Mineral transport across the placenta S M Husain, M Z Mughal Personal view 879 Putting the clock back 30 years: neonatal care since the 1991 NHS reforms Catherine Pope, David Wild Perinatal lessons from the past 882 Dr Thomas Denman of London (1733-1815): rupture of the membranes and management of the cord PM Dunn 885 Letters to the editor 887 Book reviews No 7 JULY 1992 Annotations 889 Angelman's syndrome Jill Clayton-Smith 891 Psychological treatments for childhood asthma Bryan Lask Original articles 892 Cryptorchidism: a prospective study of 7500 consecutive male births, 1984-8 John Radcliffe Hospital Cryptorchidism Study Group 900 Birth weight and hospital admission before the age of 2 years Lesley Mutch, Hazel Ashurst, Alison Macfarlane 905 Suspected child abuse: cost in medical time and finance C L Summers, E M Molyneux Commentary-CJ Hobbs Response from the authors 911 Screening of hearing impairment in the newborn using the auditory response cradle S M Tucker,J Bhattacharya 920 Growth of infants with neonatal growth hormone deficiency J M Wit, H van Unen 925 Sleep related upper airway obstruction and hypoxaemia in sickle cell disease Martin P Samuels, Valerie A Stebbens, Sally C Davies, et al 930 Sequelae of haemolytic uraemic syndrome A Schlieper, P C Rowe, E Orrbine, et al 935 Randomised trial of a ready-to-feed compared with powdered formula A Lucas, S Lockton, Peter S W Davies 940 Management and response to treatment of Helicobacterpylori gastritis MJ Mahony,J I Wyatt,J M Littlewood 944 Transient hypothyroxinaemia associated with developmental delay in very preterm infants WouterJf Meijer, S Pauline Verloove-Vanhorick, Ronald Brand, et al 948 Positive rolandic sharp waves in the EEG of the premature newborn: a five year prospective study Stephane Marret, Dominique Parain, EmmanuelJeannot, et al 952 Occurrence of suppurative lymphadenitis after a change of BCG vaccine Paul Hengster,J_org Schnapka, Manfred Fille, et al 956 JC virus associated meningoencephalitis in an immunocompetent girl Kim Blake, Deenan Pillay, Wendy Knowles, et al 958 Necrobacillosis with pancytopenia M Epstein, A DJ Pearson, SJ Hudson, et al 960 Protein S deficiency: early presentation and pulmonary hypertension J O'Sullivan, R Chatuverdi, M K Bennett, et al Current topics 962 Myelodysplastic syndromes Ian M Hann 967 Children of parents in prison Dora Black Types of psychiatric treatment 971 (6) Psychiatric treatment for children-the organisation of services Fiona Subotsky Regular review 976 Recent progress in intestinal transplantation Celia Ingham Clark 980 Letters to the editor Archivist 899, 904, 910, 919, 924, 934, 975 No 8 AUGUST 1992 Annotations 981 Current status of definitive surgery for congenital heart disease B Sethia 983 The molecular basis of nephrogenesis and congenital kidney disease J'onathan Bard Original articles 985 Haemorrhagic shock encephalopathy syndrome in the British Isles CJ7 Bacon, S M Hall 994 Optimum method for administration of biosynthetic human growth hormone R Stanhope, A Albanese, L Moyle, et al 998 Plasma and cerebrospinal fluid arginine vasopressin in patients with and without fever PM Sharples, J R Seckl, D Human, et al 1003 Cord blood lymphocyte responses to food antigens for the prediction of allergic disorders Naomi Kondo, Yuki Kobayashi, Shinji Shinoda, et al 1008 Risk of developing atopic disease after early feeding with cows' milk based formula D Gustafssom, TLowhagen, K Andersson 1011 Newly diagnosed diabetes: a study of parental satisfaction D N Lessing, P G F Swift, M A Metcalfe, et al 1014 Prevention of exercise induced asthma by inhaled salmeterol xinafoate C P Green,3J F Price 1018 Genetic risk for asthma, allergic rhinitis, and atopic dermatitis Sigrid Dold, Matthias Wjst, Erika von Mutius, et al 1023 Early immune responses to Dermatophagoides pteronyssinus and atopic predisposition R G G Ruiz, D M Kemeny, F Mariani, et al 1027 Breast feeding and oral rehydration at home during diarrhoea to prevent dehydration A S G Faruque, D Mahalanabis, A Islam, et al 1030 Reversible cerebral shrinkage in kwashiorkor: an MRI study Geney D Gunston, Dawn Burkimsher, HesterMalan, et al 1033 Reversible mitochondrial myopathy with cytochrome c oxidase deficiency Matti K Salo, Juhani Rapola, Hannu Somer, et al 1036 Recurrent parotitis Herman A Cohen, Samuel Gross, Moshe Nussinovitch, et al 1038 Solitary mastocytoma causing recurrent blistering in infancy Colin S Munro, Peter M Farr 1039 Pituitary gigantism P W Lu, M Silink, I Johnston, et al Challenges 1042 Paediatric care in Hungary Dezso Schuler Types of psychiatric treatment 1046 (7) Paediatric liaison Shirley A Leslie Current topics 1050 Cerebral palsy-an increasing contributor to severe mental retardation Amanda Nicholson, Eva Alberman 1056 Guidelines for management of idiopathic thrombocytopenic purpura O B Eden, J S Lilleyman on behalfofthe British Paediatric Haematology Group 1059 Letters to the editor 1060 Book reviews Archivist 997, 1002, 1045 No 9 SEPTEMBER 1992 1061 James Spence Medallist 1992 Annotations 1063 The radiological dating of injuries S Chapman 1065 Fungal skin infections R 7Hay Original articles 1068 Paediatric outpatient utilisation in a district general hospital R MacFaul, R Long 1073 Audit of screening for congenital hypothyroidism P O D Pharoah, M P Madden 1077 How much nebulised budesonide reaches infants and toddlers? K C Lodrup Carlsen, K Nikander, K-H Carlsen 1080 What do parents know about vitamins? ML B Ko, N Ramsell,J A Wilson 1082 Effect of taurine supplementation on fat and energy absorption in cystic fibrosis M De Curtis, F Santamaria, P Ercolini, et al 1086 The value of serum IgG titres against Pseudomonas aeruginosa in the management of early pseudomonal infection in cystic fibrosis M M Brett, Ej Simmonds, A TM Ghoneim, et al 1089 Management of hypertensive emergencies J E Deal, TM Barratt, MJ Dillon 1093 Early thrombocytopenia in HIV infection R M Beattie,7 Q Trounce, E G Hermione, et al 1095 Thymopentin treatment in severe atopic dermatitis-clinical and immunological evaluations Kue-Hsiung Hsieh, Men-Fang Shaio, Tung-Nan Liao 1103 Policies for control of communicable disease in day care centres A Chouillet, H Maguire, Z Kurtz 1107 Endocrine deficit after fractionated total body irradiation A L Ogilvy-Stuart, DJ Clark, W H B Wallace, et al 1111 Is hearing assessed after bacterial meningitis? H M Fortnum, D Hull 1112 Toxic shock-like syndrome caused by adenovirus infection K Bojang, M D S Walters 1114 Accidental ingestion of 'Ecstasy' (3,4-methylenedioxymethylamphetamine) A R Bedford Russell, R H Schwartz, S Dawling Controversy 1116 Avoiding chemotherapy related late effects in children with curable tumours C Ross Pinkerton Types of psychiatric treatment 1120 (8) Inpatient psychiatry units Jonathan Green Current topics 1124 Liver transplantation Judith Chiyende, Alex P Mowat 1128 Hearing impairment after bacterial meningitis: a review H M Fortnum 1134 Letters to the editor 1136 Book reviews Archivist 1072, 1102, 1119, 1127, 1133 No 10 OCTOBER 1992 1137 1139 1140 1146 1154 1162 1166 1169 1174 FETAL AND NEONATAL EDITION Annotations Herpes simplex virus infection in pregnancy David McIntosh, David Isaacs Kidney function in the very low birthweight infant j TBrocklebank Original articles Renal function in sick very low birthweight infants: 1. Glomerular filtration rate Barrv H Wilkins Renal function in sick very low birthweight infants: 2. Urea and creatinine excretion Barry H Wilkins Renal function in sick very low birthweight infants: 3. Sodium, potassium, and water excretion Barry H Wilkins Renal function in sick very low birthweight infants: 4. Glucose excretion Barry H Wilkins Simultaneous measurement of preductal and postductal oxygen saturation by pulse oximetry in hyaline membrane disease P D Macdonald, V Y H Yu Effect of patency of the ductus arteriosus on blood pressure in very preterm infants Nick Evans, james Moorcraft Annual audit of neonatal morbidity in preterm infants R W I Cooke 1177 Prediction of neurodevelopmental outcome in the preterm infant: short latency cortical somatosensory evoked potentials compared with cranial ultrasound L S de Vries, P Eken, V Pierrat, et al 1182 Membrane humidification-a new method for humidification of respiratory gases in ventilator treatment of neonates L Hanssler, W Tennhoff, C Roll 1185 Randomised controlled trial of colloid infusions in hypotensive preterm infants E F Emery, A Greenough, H R Gamsu 1189 Cardiac tumours in intrauterine life Alison M M Groves, Nuala L K Fagg, Andrew C Cook, et al 1193 Changes in the plasma aminogram of parenterally fed infants treated with dexamethasone for bronchopulmonary dysplasia P C Ng, K G Brownlee, EJ Kelly, et al 11% Coagulation screening tests in high risk neonates: a prospective cohort study B K Schmidt, P Vegh, M Andrew, et al 1198 Clinical application of urine antigen detection in early onset group B streptococcal disease E D G McIntosh, H E Ieffrey 1201 Recovery of intralipid from lumbar puncture after migration of saphenous vein catheter Felix Odaibo, Carlos A Fajardo, Catherine Cronin 1204 Meconium ileus in the absence of cystic fibrosis Khoulood Fakhoury, Peter R Durie, Henry Levison, et al 1207 Validation of a portable indirect calorimetry system for measurement of energy expenditure in sick preterm infants GJ Shortland, PJ Fleming,3t H Walter 1212 Fatal perinatal nephropathy with onset in intrauterine life RJ Scot, M Rochefort 1214 When will my baby go home? PeterJ Powell, Colin V E Powell, Sally Hollis, et al 1217 Intermittent ductal patency in healthy newborn infants: demonstration by colour Doppler flow mapping M K Lim, K Hanretty, A B Houston, et al 1219 Neonatal meningococcal conjunctivitis associated with meningococcal meningitis M Ellis, A M Weindling, D C Davidson, et al Special report 1221 Development of audit measures and guidelines for good practice in the management of neonatal respiratory distress syndrome-Report of a Joint Working Group of the British Association of Perinatal Medicine and the Research Unit of the Royal College of Physicians Controversy 1228 Surfactant replacement therapy-time for thought G McClure Commentary-ColinJ Morley Current topic 1231 Diagnosis and management of inborn errors of metabolism-an update J E Wraith Personal practices 1233 Initial experience of screening for retinopathy of prematurity D I Clark, C O'Brien, A M Weindling, et al 1237 The unreactive fetal heart rate 7 S Smoleniec, D KJames Perinatal lessons from the past 1242 Felix Wurtz of Basel (1518-75) and clubfeet PeterM Dunn 1244 Letters to the editor No 10 OCTOBER 1992 Annotations 1245 Drug abuse in children and adolescents: an update Harith Swadi 1247 Consent to treatment in childhood AlexanderMcCall Smith 1248 Molluscum contagiosum Allan S Highet Original articles 1250 Effects of oral and intramuscular vitamin K prophylaxis on vitamin K, PIVKA-II, and clotting factors in breast fed infants EA M Cornelissen, LA A Kollee, R A DeAbreu, etal 1255 Oscillations of body temperature at night PJBrown, R A Dove, CS Tuffnell, etal 1259 Factors affecting the development of night time temperature rhythms M R Lodemore, S A Petersen, M P Wailoo 1262 Paediatric cardiac transplantation with steroid-sparing maintenance immunosuppression J Au,J W Gregory, I W Colquhoun, et al 1267 Intravenous immunoglobulin in HIV-I infected haemophilic patients N Wagner, R Bialek, H Radinger, et al 1272 Gastrointestinal complications of gastrocystoplasty B D Gold, P S Bhoopalam, R M Reifen, et al 1277 Prepubertal height velocity references over a wide age range B Rikken,J M Wit Commentary-R Stanhope Bone age, social deprivation, and single parent families TJ Cole, A J L Cole Centiles for adult head circumference KM DBushby, TCole,J N S Matthews, eta! Immunisation status in inner London primary schools H E Bedford,3t I Masters, Z Kurtz An audit of preschool vision screening J3ohn WAllen, Bratati Bose Microfollicular thyroid adenoma and congenital goitrous hypothyroidism A J Alabbasy, L Delbridge, R Eckstein, et al 12% Oral hairy leukoplakia in vertically and horizontally acquired HIV infection D Nadal, B de Roche, M Buisson, et al 1281 1286 1288 1292 1294 Current topic 1298 Building a combined child health service Margaret R S Barker, RJ Purvis Types of psychiatric treatment 1302 (9) Consultative work in child and adolescent psychiatry Derek Steinberg Statistics from the inside 1306 7. Regression and correlation MJ R Healv Regular review 1310 Recent advances in understanding muscular dystrophy K M D Bushby Personal practice 1313 Investigation of metabolic disorders resembling Reye's syndrome Anne Green, Susan M Hall 1318 Letters to the editor 1320 Autumn books Archivist 1276, 1285 Correction 1324 Early thrombocytopenia in HIV infection Beattie et al No 11 NOVEMBER 1992 Annotations 1325 Silent gastro-oesophageal reflux: how much do we miss? I WBooth 1327 Excitatory amino acid neurotoxicity-a broader horizon for cerebral protection? Robert C Tasker Original articles 1330 Psychological effects of sodium valproate and carbamazepine in epilepsy G Stores, P L Williams, E Styles, et al 1338 Diagnostic significance of "mTc-dimercaptosuccinic acid (DMSA) scintigraphy in urinary tract infection BJrakobsson, S Soderlundh, U Berg 1343 Foregut motor function in chronic renal failure A M Ravelli, S E Ledermnann, WM Bisset, et at 1348 Ultrasonographic assessment of the extent of hepatic steatosis in severe malnutrition J F Doherty, EJ3 Adam, G E Griffin, et al 1353 Delayed surgery for congenital diaphragmatic hernia: neurodevelopmental outcome in later childhood Mark Davenport, Elise Rivlin, S W D'Souza, et al 1357 Adult height in constitutionally tall stature: accuracy of five different height prediction methods E Ejloss, R Temperli, P E Mullis 1363 Incidence of hepatic hamartomas in tuberous sclerosis SJ3dzwiak, M Pedich, P Rajszys, et al 1366 Increased resting energy expenditure in childhood asthma: does this contribute towards growth failure? S R Zeitlin, S Bond, S Wootton, et al 1370 Defective alloantigen-presenting capacity of 'Langerhans cell histiocytosis cells' Raymond C H Yu,Jenny F Morris, Jon Pritchard, et al 1373 Interleukin-2 in relation to T cell subpopulations in rheumatic heart disease Magdy M Zedan, Farha A El-Shennauy, HelmyM Abou-Bakr, et al 1376 Bronchoscopy in lipoid pneumonia M Kameswaran, S HAnnobil, B Benjamin, etal 1378 Causes of death in children diagnosed with non-Hodgkin's lymphoma between 1974 and 1985 C M Robertson, C A Stiller,J E Kingston 1384 Antiphospholipid antibody associated thrombosis in juvenile chronic arthritis Roberto Caropali, Angelo Ravelli, Barbara Ramengli, et al 1385 Severe anaemia and ileocolic anastomotic ulceration A H Hamilton, J M Beck, G M Wilson, etal Personal practice 1387 Intercurrent illness in inborn errors of intermediary metabolism Marijorie A Dixon,J V Leonard Types of psychiatric treatment 1392 (10) Treatment of delinquents CarolSheldrick Current topics 1398 Should we use dexamethasone in meningitis? The Meningitis Working Party ofthe British Paediatric Immunology and Infectious Diseases Group 1402 African children in Britain Anne Nesbitt, Margaret A Lynch Chalienges 1406 Challenges for child health in Australia R Kim Oates 1410 Letters to the editor 1415 Book reviews Archivist 1337, 1352, 1401 No 12 DECEMBER 1992 Annotations 1417 The place of computed tomography and lumbar puncture in suspected bacterial meningitis David H Mellor 1420 Sleep problems Gregory Stores 1421 Routine discharge examination of babies-is it necessary? P H T Cartlidge Original articles 1423 Do maternal and intrauterine factors influence blood pressure in childhood? P H Whincup, D G Cook, 0 Papacosta 1430 Management and outcome of severe head injuries in the Trent region 1985-90 A C Elias-J3ones,J A G Punt, A E Turnbull, et al 1436 Long term effects of periconceptional multivitamin supplements for prevention of neural tube defects: a seven to 10 year follow up Monica Holmes-Siedle, Jennifer Dennis, R H Lindenbaum, eta! 1442 A randomised trial of low dose folic acid to prevent neural tube defects Peadar N Kirke, Leslie E Daly, J Harold Elwoodfor the Irish Vitamin Study Group 1447 Immunohistochemical features of the portal tract mononuclear cell infiltrate in chronic aggressive hepatitis Giorgio Senaldi, Bernard Portmann, Alex P Mowat, et al 1454 Bronchial responsiveness and lung function in infants with lower respiratory tract illness over the first six months of life Jane R Clarke, Amanda Reese, Michael Silverman 1459 Association of perinatal events, epilepsy, and central nervous system trauma with juvenile delinquency Paula Rantakallio, Markku Koiranen, Jyrki Mottonen 1462 Urinary protein/creatinine index in follow up of patients with Wilms' tumour after nephrectomy C Mpofu, J R Mann 1467 Teachers' perceptions of epilepsy M J Bannon, C Wildig, P WJones 1472 Growth hormone deficiency during puberty reduces adult bone mineral density S L Hyer, D A Rodin, J H Tobias, et al 1475 Hazards of parenteral treatment: do particles count? J W L Puntis, K M Wilkins, P A Ball, et al 1478 Sinusitis-induced subdural empyema Ruth Skelton, Wirginia Maixner, David Isaacs 1481 Familial pancreatic enzyme insufficiency G Owen, P WBuss, H RJenkins, etal 1483 Thrombolysis with low dose tissue plasminogen activator E Doyle, J Britto,J Freeman, etal 1484 Fatal encephalitis/encephalopathy in primary human herpesvirus-6 infection YAsano, T Yoshikawa, YKajita, et al 1486 Recovery of protein from urine specimens collected in cotton wool G C Smith, C M Taylor Types of psychiatric treatment 1488 (11) Drug treatment Michael Prendergast Statistics from the inside 1495 8. Size, power, and confidence MJ3 R Healv Current topics 1498 The ethics of cardiopulmonary resuscitation. I. Background to decision making J M Davies, B M Reynolds 1502 The ethics of cardiopulmonary resuscitation. II. Medical logistics and the potential for good response 7 M Davies, B M Reynolds 1506 Suitability of the paediatric setting for hospitalised adolescents M L Gillies, W Ll Parry-Jones Personal practice 1510 Factitious illness: recognition and management D M Eminson, RJ Postlethwaite 1517 Referees and staff 1519 Letters to the editor 1521 Index Archivist 1441, 1446
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