Department of Children’s Surgery BIENNIAL REPORT 2011-2013 Surgery cover v2.indd 1 1/23/14 1:30 PM Table of Contents INTRODUCTION 1 DIVISIONAL REPORTS: HEART INSTITUTE 2 MATERNAL FETAL MEDICINE 16 NEUROSURGERY 22 OPHTHALMOLOGY 30 ORTHOPEDICS & SCOLIOSIS 34 PEDIATRIC OTOLARYNGOLOGY 48 PATHOLOGY 64 SURGERY & TRAUMA 70 PEDIATRIC UROLOGY 74 Surgery cover final.indd 2 1/27/14 9:13 AM Dear Friends & Colleagues, We are excited to present the third biennial Rady Children’s Specialists of San Diego, A Medical Foundation, Department of Children’s Surgery 2011-2013 report. This report is a culmination of the accomplishments of our surgeons and surgeon-scientists following the inception of the medical foundation at Rady Children’s Hospital-San Diego (RCHSD) in September 2009. The Department of Surgery of the medical foundation includes clinically active members of the hospital divisions of: Cardiovascular Surgery Maternal and Fetal Medicine Neurosurgery Pediatric General Surgery Ophthalmology Orthopedics Otolaryngology and Urology Head and Neck Surgery The medical practice foundation has provided a structure for the surgical faculty to work collaboratively to improve surgical clinical care, education, and enhance research activities. Members of the department are faculty in the Departments of Surgery, Orthopedics, Reproductive Medicine and Neurosciences at the University of California, San Diego (UC San Diego). The foundation has fostered even greater synergy between surgical colleagues at UC San Diego and RCHSD. This partnership has allowed the department to continue to provide world class surgical care for the region’s patients and families. RCHSD has continued to grow its surgical volume, performing greater than 21,000 operative cases in the last year. We are also very close to performing our first cardiac transplant procedure after successfully attracting a world class pediatric cardiac transplant surgeon. Our new Cardiovascular Intensive Care Unit is providing the best of care to our Heart Institute patients. A new surgical academic fund has been created in partnership with RCHSD to help finance surgical research on campus and to leverage our electronic medical record. This complements the remarkable basic science achievements of the research faculty at UC San Diego. RCHSD is committed to providing the best of care for children through research and clinical expertise. Sincerely, surgery intro v1.indd 1 Donald B. Kearns, MD Kathleen A. Sellick Herbert C. Kimmons, MD Surgeon-In-Chief, Rady Children’s Specialists of San Diego, A Medical Foundation President and CEO Rady Children’s Hospital-San Diego Executive Director, Rady Children’s Specialists of San Diego, A Medical Foundation 1/23/14 1:31 PM Heart Institute CARDIOLOGY Rady Children’s Heart Institute was created to integrate and coordinate the clinical, research and educational programs of the Cardiology and Cardiovascular Surgery Divisions at Rady Children’s Hospital-San Diego (RCHSD). The Division of Cardiology currently includes 13 full time cardiologists. Recruitments since July 2012 include: Dr. Fagan, a general cardiologist who joined the Cardiology Division in January 2013, Dr. Sun, an expert in fetal echo and imaging who joined the Cardiology Division in August 2013, and Dr. Hedge, an expert in cardiac MRI and imaging who joined the Cardiology Division in August 2013. heart institute-surgery v5.indd 2 1/27/14 10:21 AM FACULTY John W. Moore, MD, MPH, Division Chief, Professor of Clinical Pediatrics; Medical Director of Division of Cardiology, RCHSD; Medical Director, Cardiac Catheterization Laboratory, RCHSD Christopher K. Davis, MD, PhD, Assistant Clinical Professor of Pediatrics; Medical Director of Exercise Laboratory, RCHSD Howaida G. EL-Said, MD, PhD, Associate Professor of Pediatrics Jeffrey R. Frazer, MD, Associate Clinical Professor of Pediatrics Raymond R. Fripp, MD, Clinical Professor of Pediatrics; Medical Director of Echocardiography Laboratory, RCHSD Paul D. Grossfeld, MD, Associate Clinical Professor of Pediatrics; Director of Pediatric Cardiology Fellowship Program Sanjeet Hegde, MD, HS Assistant Clinical Professor Stanley E. Kirkpatrick, MD, Associate Clinical Professor of Pediatrics, retired (volunteer faculty) Delaram Molkara, MD, Assistant Clinical Professor of Pediatrics Vishal Nigam, MD, Assistant Professor of Pediatrics in Residence James C. Perry, MD, Clinical Professor of Pediatrics; Medical Director of Electrophysiology, Pacing and Adult Congenital Heart Disease, RCHSD Beth Printz, MD, Associate Professor of Clinical Pediatrics; Medical Director of Non-Invasive Cardiac Imaging, RCHSD Heather Sun, MD, HS Assistant Clinical Professor POSTDOCTORAL FELLOWS Mohammad Ebrahim, MD 1st year, UCSD Serena Sah, MD, 2nd year, UCSD Gabrielle Vaughn, MD, 3rd year, UCSD Juliana Gomez-Arostegui, MD, 3rd year, UCSD Matthew Williams, MD, 3rd year, UCSD Kiran Mallula, MD, 4th year Interventional Clinical Fellow, UCSD Left to Right: Howaida El-Said, Jeffrey Frazer, Beth Printz, Sanjeet Hedge, James Perry Heart Institute heart institute-surgery v5.indd 3 3 1/27/14 10:43 AM CLINICAL ACTIVITIES INPATIENT/OUTPATIENT The Cardiology Division is the only comprehensive tertiary care provider of cardiovascular services in the region (San Diego, Imperial, and South Orange Counties), and it receives referrals from Balboa Naval Medical Center, as well as the San Diego Regional Kaiser Medical Center. In addition, the Division is the major off island referral center for the State of Hawaii. The Division’s clinical volumes for the academic year 2012-2013 were 12,085 total outpatient visits including 1397 patients seen in satellite offices. 697 catheterizations were performed, about 70% 4 of which were interventional catheterizations. The echocardiography laboratory performed 9511 echocardiograms. In the last five years there has been steady growth in all categories. The growth of the division clinical volumes has been related both to expanding the referral practice within Southern California and neighboring states, as well as to meeting previously unmet demand for services within the traditional referral regions. The Division’s clinical volumes place the program among the largest pediatric and congenital heart disease centers in the United States. Left to Right: Brian Fagan, Vishal Nigam, John Moore, Heather Sun, Paul Grossfeld, Delaram Molkara, Christopher Davis, Raymond Fripp Heart Institute heart institute-surgery v5.indd 4 1/27/14 10:44 AM RESEARCH ACTIVITIES The Division’s basic and translational research program is anchored by Dr. Paul Grossfeld and Dr. Vishal Nigam. Dr. Grossfeld investigates the genetic basis of congenital heart defects and Jacobsen’s Syndrome (11qdel). His additional projects include induced Pleuripotent Stem Cells to derive cardiac lineages from human Jacobsen syndrome patient fibroblasts (“Disease in a Dish”); defining gene regulatory pathways involving ETS-1 in cardiac neural crest cell development, and pathways that suppress the development of heart defects; and the genetic basis of cognitive and behavioral defects in Jacobsen syndrome. Dr. Nigam’s laboratory is focused on investigating the molecular and genetic mechanisms involved in aortic valve stenosis and in valve calcification. In addition, he is studying the role of biomechanical stretch on activation of calcification pathways and the role of biomechanical stressors on cardiac defects, and the mechanism of how stretch and shear stress stimulate ventricular growth in utero. The Division’s faculty and fellows have also been involved in a large number of clinical research projects. There are currently 31 active IRB approved clinical projects: Christopher Davis, MD, PhD Determining the Natural and “Unnatural” history of Anomalous Aortic Origin of a Coronary Artery with Interarterial or Intraconal or Intramural Course (AAOCA): Establishing a Multi-Institutional Registry The Hybrid Procedure as an Alternative to the Norwood Sano in High Risk Hypoplastic Left Heart (HLHS) Patients (Retrospective Chart Review) Howaida El-Said, MD, PhD ADO II Clinical Study Closure of Muscular Ventricular Septal Defects with the AMPLATZER Muscular VSD Occluder–Post Approval Study native to the Norwood Sano in High Risk Hypoplastic Left Heart (HLHS) Patients (Retrospective Chart Review) Use of the Melody Transcatheter Pulmonary Valve Ensemble (Melody TPV) as a Humanitarian Use Device (HUD) under a Humanitarian Device Exemption (HDE) HDE#: H080002 designated July 10, 2007 and approved January 25, 2010–HUD #07-0810 The Damus-Kaye Stansel (DKS) Surgical Procedure: Quality of Life After DKS Continued Access to Covered Cheatham Platinum Stent for Prevention or Treatment of Aortic Wall Injury Associated with Aortic Coarctation (COAST II CA) Coarctation of the Aorta Stent Trial (COAST ) Phase I Implantation of the Medtronic Melody Transcatheter Pulmonary Valve (TPV) in Patients with Dysfunctional Right Ventricular Outflow Tract (RVOT) Conduits: A Post Market Approval Study Covered Cheatham-Platinum Stent for Prevention or Treatment of Aortic Wall Injuries Associated with Aortic Coarctation (COAST II) The Damus-Kaye Stansel (DKS) Surgical Procedure: Long-term Follow-up of Survivors and Analysis of Possible Sequelae Congenital Cardiac Catheterization Outcomes Project (C3PO) Protocol Version 3–May 2009 Congenital Cardiac Catheterizations Project on Outcomes (C3PO) Quality Improvement Registry Congenital Cardiac Catheterizations Project on Outcomes (C3PO-QI) Quality Improvement–Radiation Project Transcatheter Closure of Atrial Septal Defect (ASD) using the Amplatzer Septal Occluder with Transthoracic Echocardiography or Transesophageal Echocardiography Pulmonary Artery Repair with Covered Stents (PARCS): The Use of Covered Cheatham Platinum Stents for Repair of RV to PA Conduits Disruption During Preparation for Implantation of the Melody Transcatheter Pulmonary Valve–Pending IRB Approval Jeffrey Frazer, MD Outcomes in Preterm and Low Birthweight Newborns Undergoing Cardiac Surgery Raymond Fripp, MD Trial of Beta Blocker Therapy (Atenolol) vs. Angiotensin II Receptor Blocker Therapy (Losartan) in Individuals with Marfan Syndrome. This study is sponsored by the National Heart, Lung & Blood Institute (NHLBI) of the National Institutes of Health (NIH), through the Pediatric Heart Network (PHN). New England Research Institutes serves as the Data Coordinating Center (DCC) for the PHN Network under grant No. U01 HL68270, CFDA # 93.837. IND#76,539 Paul Grossfeld, MD Trial of Beta Blocker Therapy (Atenolol) vs. Angiotensin II Receptor Blocker Therapy (Losartan) in Individuals with Marfan Syndrome. This study is sponsored by the National Heart, Lung & Blood Institute (NHLBI) of the National Institutes of Health (NIH), through the Pediatric Heart Network (PHN). New England Research Institutes serves as the Data Coordinating Center (DCC) for the PHN Network under grant No. U01 HL68270, CFDA # 93.837. IND#76,539 John W. Moore, MD, MPH Pulmonary Artery Repair with Covered Stents (PARCS): The Use of Covered Cheatham Platinum Stents for Repair of RV to PA Conduits Disruption During Preparation for Implantation of the Melody Transcatheter Pulmonary Valve–Pending Approval Continued Access to Covered Cheatham Platinum Stent for Prevention or Treatment of Aortic Wall Injury Associated with Aortic Coarctation (COAST II CA) Coarctation of the Aorta Stent Trial (COAST ) Phase I Implantation of the Medtronic Melody Transcatheter Pulmonary Valve (TPV) in Patients with Dysfunctional Right Ventricular Outflow Tract (RVOT) Conduits: A Post Market Approval Study Covered Cheatham–Platinum Stent for Prevention or Treatment of Aortic Wall Injuries Associated with Aortic Coarctation (COAST II) Congenital Cardiac Catheterization Outcomes Project (C3PO) Protocol Version 3–May 2009 Use of the Melody Transcatheter Pulmonary Valve Ensemble (Melody TPV) as a Humanitarian Use Device Heart Institute heart institute-surgery v5.indd 5 5 1/23/14 4:37 PM (HUD) under a Humanitarian Device Exemption (HDE) HDE#: H080002 designated July 10, 2007 and approved January 25, 2010–HUD #07-0810 ADO II Clinical Study Closure of Muscular Ventricular Septal Defects with the AMPLATZER Muscular VSD Occluder–Post Approval Study Transcatheter Closure of Atrial Septal Defect (ASD) using the Amplatzer Septal Occluder with Transthoracic Echocardiography or Transesophageal Echocardiography Congenital Cardiac Catheterization Outcomes Project (C3PO) Protocol Version 3–May 2009 Congenital Cardiac Catheterizations Project on Outcomes (C3PO-QI) Quality Improvement Registry Congenital Cardiac Catheterizations Project on Outcomes (C3PO-QI) Quality Improvement–Radiation Project The Hybrid Procedure as an Alternative to the Norwood Sano in High Risk Hypoplastic Left Heart (HLHS) Patients (Retrospective Chart Review) Vishal Nigam, MD MicroRNA Profiling in Neonates Undergoing Cardiopulmonary Bypass Profiling of Tissues from Patients with Congenital Heart Defects Modeling Hemodynamic Stresses in Congenital Heart Disease Retrospective Profiling of Hypoplastic Left Heart Ventricular Tissue The Damus-Kaye Stansel (DKS) Surgical Procedure: Quality of Life After DKS The Damus-Kaye Stansel (DKS) Surgical Procedure: Long-term Follow-up of Survivors and Analysis of Possible Sequelae James Perry, MD Transmural Atrial Leads in Adult Congenital heart patients: Lead Performance in Long-Term Follow-Up (Retrospective Chart Review) SPKLS002: Echocardiographic Assessment of Cardiac Left Ventricular Strain, Torsion and Blood Flow Analysis in Subjects with Congenital and Acquired Heart Disease 6 A Retrospective Study of Children Presenting with Tachycardia-Mediated Cardiomyopathy The Damus-Kaye Stansel (DKS) Surgical Procedure: Quality of Life After DKS Outcomes in Preterm and Low Birthweight Newborns Undergoing Cardiac Surgery Beth Printz, MD, PhD SPKLS002: Echocardiographic Assessment of Cardiac Left Ventricular Strain, Torsion and Blood Flow Analysis in Subjects with Congenital and Acquired Heart Disease Implantation of the Medtronic Melody Transcatheter Pulmonary Valve (TPV) in Patients with Dysfunctional Right Ventricular Outflow Tract (RVOT) Conduits: A Post Market Approval Study Use of the Melody Transcatheter Pulmonary Valve Ensemble (Melody TPV) as a Humanitarian Use Device (HUD) under a Humanitarian Device Exemption (HDE) HDE#: H080002 designated July 10, 2007 and approved January 25, 2010–HUD #07-0810 TEACHING ACTIVITIES The Division provides a comprehensive accredited educational program for fellowship training in pediatric cardiology. Dr. Grossfeld is the Fellowship Program Director. Fellows are offered clinical teaching and mentoring in all aspects of clinical cardiology: Outpatient care and evaluation, Inpatient and ICU care Echocardiography, CT and MRI, Diagnostic and Interventional Cardiac Catheterization, Electro-physiology and Pacing, Exercise Physiology and Clinical Research. A broad schedule of lectures and presentations are offered including: Weekly Surgery Conference, Weekly Catheterization Conference, Weekly Core Lecture, and Monthly Journal Club and Research Meeting. The three-year program has full ACGME accreditation. The Division offers a fourth year position for an Advanced Fellow in interventional congenital cardiology. This position includes training and experience as operator or first assistant in approximately 200 procedures, teaching conferences, and training in clinical research. Faculty/staff cardiologists are also active in training of pediatric residents and medical students. Rotation in pediatric cardiology is not mandatory for residents, but many selected the one month Pediatric Cardiology elective designed by Dr. Perry. This elective provides both inpatient and outpatient experiences. Dr. Davis participates as an Instructor in the “Clinics” course required for second year medical students. AWARDS, HONORS, AND MAJOR PRESENTATIONS Christopher Davis, MD, PhD Angadi SS, Weltman NT, Patrie JT, Barrett EJ, Weltman A, Brock DW, Irving B, Davis CK, Rodriguez J, Gaesser GA. Effects of a low-carbohydrate vs. high-carbohydrate, high-fiber diet on soluble cell adhesion molecules and endothelial function in adults with metabolic syndrome. Experimental Biology Conference, April 2012 Howaida EL-Said, MD, PhD Randomized trial of transthoracic echocardiography versus transesophageal echocardiography for definitive assement and guidance of transcatheter closure of ASDs in children using the Ampaltzer Septal Occluder. Pediatric Interventional Cardiac Symposium (PICS), Boston, MA, July 2011 A risk stratified algorithm for eclectic use of hybrid palliation in high risk neonates. PICS, Boston, MA, July 2011 Use of TPA for femoral artery obstruction post catheterization. PICS, Boston, MA, July 2011 First report of atretic coronary sinus stenting resulting in dramatic improvement of ventricular function in functional single ventricle. PICS, Boston, MA, July 2011 Fetal Echocardiography from the Sonographer to the Interventionalist. Genetic Ultrasound, Basic Sonography and Hands-On Patient Scanning. Schaetzel Center, San Diego, CA, March 2012 Heart Institute heart institute-surgery v5.indd 6 1/23/14 4:37 PM Breaking the Limits-Extensibility of Medium and Large Stents. Presented in PICS, April 2012 Walking on Ice with the GUCH. Interventions for Adults with Congenital Heart Disease. Invited speaker. Maui Cardiovascular Symposium, September 2012 Prospective Randomized Trial of Trans-thoracic Echocardiography (TTE) vs. Trans-esophageal Echocardiography (TEE) for Definitive Assessment and Guidance of Transcatheter Closure of Atrial Septal Defects (ASD) in Children using the Amplatzer Septal Occluder (ASO). Oral presentation PICS, Miami, FL, January 2013 Paul D. Grossfeld, MD Oral presentation, New basic and genetic insights into HLHS. American Heart Association, Orlando, FL, November 2011 Update on genes causing cognitive and behavioral disorders in 11q. Seventh European 11q Research and Resource Group meeting, Pforzheim, Germany, November 2011 The role of ETS-1 in causing human congenital heart defects. Department of Cardiology, University of Arizona School of Medicine, March 2012 John W. Moore, MD, MPH Invited Speaker, PICS–AICS, Stenting Coarctation of the Aorta. Boston, MA, July 23, 2011 Invited Speaker, Controversies in Pediatric Cardiology for the Primary Care Professional. Small PDA’s & ASD’s: Do They Need to be Closed? Orange, CA, March 3, 2012 Invited Speaker, PDA in Children and Adults. ACC.12, Chicago, IL, March 2012 Invited Speaker, IMPACT Registry. Children’s Hospital Association Meeting, San Diego, CA, April 19, 2012 Invited Speaker, IMPACT Registry. Treatment of Coarctation in Adults. SCAI, Las Vegas, NV, May 11, 2012 Invited Testimony before FDA Panel investigating ASD device safety representing American College of Cardiology, Gaithersburg, MD, May 24, 2012 Invited Speaker, Coarctation: The Case for Angioplasty and Stenting. North American Society for Cardiovascular Imaging, Pasadena, CA, October 15, 2012 Invited Speaker, Embolization Therapy in Congenital Heart Disease. ACC 13, March 9, 2013, San Francisco, CA Moderated Abstract, IMPACT Registry: First Review of Community Practice with Respect to Device Closure of ASD and PDA. ACC 13, San Francisco, CA, March 12, 2013 Invited Speaker, WSOPC, Melody Valve. Monterey, CA, June 8, 2013 James Perry, MD Device therapy in adult congenital heart patients: saving lives? Prague Symposium on Congenital Heart Disease, Prague, Czech Republic, December 2011 Adults with Congenital Heart Disease: What Does Transition Look Like? UCSD/Rady Children’s Grand Rounds, San Diego, CA, December 2011 When is Primary Prevention ICD Therapy an Appropriate Consideration in Adult CHD? Evolving Concepts in CV Management Symposium, San Diego, CA, January 2012 Pacemaker implantation in children and adults with congenital heart disease. Pacemaker and ICD therapy in complex congenital heart disease, State of the Art Pediatric and CHD Electrophysiology. 4th Asia-Pacific Pediatric Cardiology Society Symposium, Taipei, Taiwan, April 2012 Good Old Antiarrhythmic Therapy. Heart Rhythm Society Annual Sessions, Boston, MA, May 2012 Beth Printz, MD, PhD Invited Speaker, Conference on Sudden Cardiac Arrest in Children, Anaheim, CA (Non-invasive Imaging), 2011 MRI assessment of cardiac tumors. International Society for Cardiac MR, January 2013 Friday AM Core Cardiology Lecture– Pediatric Heart Network Review, January 2013 Pediatric Residency Noon Conference Lecture–Cardiac MRI and CT. April 2013 San Diego Society for Cardiac MRI Lecture–Case Presentation, June 2013 Heather Sun, MD Sun HY, Punn R, Selamet Tierney ES, Tacy TA. Stroke Volume is a More Precise Measurement Than Cardiac Output in the Assessment of Fetal Ventricular Function. American Society of Echocardiography Scientific Sessions, Poster Session. National Harbor, MD, 2012 Sun HY, Behzadian F, Punn R, Tacy TA. Progressive Deterioration in Left Ventricular Deformation After Pulmonary Artery Band Training and Subsequent Repair in Ventriculoarterial Discordance. American Heart Association Scientific Sessions, Poster Session, Orlando, FL, 2011 Pediatric Resident Board Review, Cyanotic Congenital Heart Disease. Lucile Packard Children’s Hospital, August, 2012 Echocardiography Laboratory Teaching Conference, Single Ventricle Reconstruction Trial Highlights, Fetal Cardiac Interventions, Measures of RV Function, Neurodevelopmental Outcomes in Congenital Heart Disease. Lucile Packard Children’s Hospital, 2012/2013 PUBLICATIONS Bergersen L, Gauvreau K, Marshall A, Kreutzer J, Beekman R, Hirsch R, Foerster S, Balzer D, Vincent J, Hellenbrand W, Holzer R, Cheatham J, Moore J, Lock J, Jenkins K. Procedure–Type Risk Categories for Pediatric and Congenital Cardiac Catheterization. Circ Cardiovasc Interv, 4:188-94, 2011. Davis CK, Pastuszko P, Lamberti J, Moore J, Hanley F, El Said H. The hybrid procedure for the border line left ventricle. Cardiol Young, 21:26-30, 2011. EL-Said H, Hamzeh R, Lamberti J, Moore JW. Catheter Balloon Adjustment of the Pulmonary Artery Band: Feasibility and Safety. Pediatr Cardiol, 32:8-13, 2011. Margossian R, Lu M, Minich LL, Bradley TJ, Cohen MS, Li JS, Printz BF, Shirali GS, Sleeper LA, Newburger JW, Colan SD. Predictors of coronary artery Heart Institute heart institute-surgery v5.indd 7 7 1/23/14 4:37 PM visualization in Kawasaki disease. J Am Soc Echocardiogr, 24:53-9, 2011. Molkara D, Tejman-Yarden S, EL-Said H, Moore JW. Pericardiocentesis of Noncircumferential Effusions Using Nonstandard catheter Entry Sites guided by Echocardiography and Fluoroscopy. Congenit Heart Dis, 6:461-465, 2011. Sheperd S, S Tejman-Yarden, S Khanna, CK Davis, A Batra. Dexmedetomidine-related atrial standstill and loss of capture in a pediatric patient after congenital heart surgery. Critical Care Medicine, 39(1):187-9, 2011. Sleeper LA, Minich LL, McCrindle BM, Li JS, Mason W, Colan SD, Atz AM, Printz BF, Baker A, Vetter VL, Newburger JW; Pediatric Heart Network Investigators. Evaluation of Kawasaki Disease Risk-Scoring Systems for Intravenous Immunoglobulin Resistance. Sleeper LA, Minich LL, McCrindle BM, Li JS, Mason W, Colan SD, Atz AM, Printz BF, Baker A, Vetter VL, Newburger JW; Pediatric Heart Network Investigators. J Pediatr, 158(5):831-835.e3, 2011. Moore J. Chest pain. In: Textbook of Clinical Pediatrics, Edited by Springer-Verlag, Berlin, 2011. Moore JW. Transcatheter valve technology: A game changer! J Am College Cardiol, 58:123-4, 2011. Pierce J, Sharma S, Hunter C, Bhombal S, Fagan B, Corchado Y, Grikscheit T, Bushman G. Intraoperative Hypercyanosis in a Patient with Pulmonary Artery Band: Case Report and Review of the Literature. Children’s Hospital Los Angeles. Anesthesia & Analgesia. (accepted for publication – June 2011). Molkara D, Tejman-Yarden S, El-Said H, Moore JW. Pericardiocentesis of noncircumferential effusions using nonstandard catheter entry sites guided by echocardiography and fluoroscopy. Congenit Heart Dis, 6(5):461-5, 2011. Backes CH, Cua C, Kreutzer J, Armsby L, EL-Said, H, Moore JW, Gauvreau K, Bergersen L, Holzer R. Low weight as an independent risk factor for adverse 8 events during cardiac catheterization of infants. Catheter Cardiovasc Interv, 2012, epublished. Davis CK, P Pastuszko, J Lamberti, J Moore, F Hanley, H El Said. The Hybrid Procedure for the Borderline Left Ventricle. Cardiology in the Young, 21(1):26-30, 2011. Bashore T, Balter S, Barac A, Byrne J, Cavendish J, Chambers C, Laskey W, Miller J, Moliterno D, Moore J, Oliver-McNeil S, Popma J, Tommaso C. American College of Cardiology Foundation/Society for Cardiovascular Angiography and Interventions Clinical Expert Consensus Document on Cardiac Catheterization Laboratory Standards Update. J Am College Cardiol, 2012; 59:2221-2305 and Catheter Cardiovasc Interv, 2012; 80:E37-49. Bratincsak A, EL-Said HG, Moore JW. Low Dose Tissue Plasminogen Activator Treatment for Vascular Thrombosis following Cardiac Catheterization in Children: A Single Center Experience. Catheter Cardiovasc Interv, 2012; epublished. Bratincsak A, Salkini A, EL-Said H, Moore JW. Percutaneous stent implantation into coronary arteries in infants. Catheter Cardiovasc Interven, 79:303-11, 2012. EL-Said HG, Bratinshak A, Gordon, BM Moore JW. Closure of Perimembranous Ventricular Septal Defects with Aneurysmal Tissue Using the Amplatzer Duct Occluder I: Lessons Learned and Medium Term Follow Up. Catheter Cardiovasc Interven, 80:895903, 2012. Perry JC, Landzberg M, Franklin W, Webb G, Chang AC. Cardiac intensive care of the adult with congenital heart disease: basic principles in the management of common problems. Pediatr Cardiol, 33:484-90, 2012. Cohen, MI, Triedman JK, Cannon BC, Davis AM, Drago F, Janousek, J, Klein GJ, Law IH, Morady FJ, Paul T, Perry JC, Sanatani, S, Tanel RE. A PACES/HRS Expert Consensus Statement on the Management of the Asymptomatic Young Patient with a Wolff-Parkinson-White (WPW) Electrocardiographic Pattern. Heart Rhythm, 6:1006-24, 2012. El-Said HG, BratincsГЎk A, Salkini, Moore JW. Percutaneous stent implantation into coronary arteries in infants. Catheter Cardiovasc Interv, 79(2):30311, 2012. Rao RP, Connolly D, Lamberti JJ, Fripp R, El Said H. Transverse aortic arch to descending aorta ratio: a new echocardiographic parameter for management of coarctation of the aorta in the infant. Congenit Heart Dis, 7(2):160-9, 2012. BratincsГЎk A, El-Said HG, Moore JW. Low dose tissue plasminogen activator treatment for vascular thrombosis following cardiac catheterization in children -a single center experience. Catheter Cardiovasc Interv, 2012 Jun. Perry JC. Pediatric and Adult Congenital Heart Disease Standards. HRS Expert Consensus Statement: EP Lab Standards: Ergonomics, Equipment, Personnel, Policy and Safety; Heart Rhythm, 2012; epub August 2012. Takao CM, El Said H, Connolly D, Hamzeh RK, Ing FF. Impact of stent implantation on pulmonary artery growth. Catheter Cardiovasc Interv, 2012 Oct 16. El Said HG, Bratincsak A, Gordon BM, Moore JW. Closure of perimembranous ventricular septal defects with aneurysmal tissue using the Amplazter Duct Occluder I: lessons learned and medium term follow up. Catheter Cardiovasc Interv, 2012 Nov. Hollander SA, Bernstein D, Yeh J, Dao D, Sun HY, Rosenthal D. Outcomes of Children Following a First Hospitalization for Dilated Cardiomyopathy. Circ Heart Failure, 5(4): 437-43, 2012. Zhang Y, Liang X, Ma J, Jing Y, Gonzales MJ, Villongco C, Krishnamurthy A, Frank LR, Nigam V, Stark P, Narayan SM, McCulloch AD. (2012) An Atlasbased Geometry Pipeline for Cardiac Hermite Model Construction and Diffusion Tensor Reorientation. Medical Image Analysis, 2012; PMID 22841777. Heart Institute heart institute-surgery v5.indd 8 1/23/14 4:37 PM Moore J, Hegde S, EL-Said H. et al. Transcatheter Device Closure of Atrial Septal Defects: A Safety Review. J Am Coll Cardiol Intv, 6:433-4442, 2013. Lin C, Hegde S, Marshall A, Porras D, Gauvreau K, Balzer D, Beekman R, Torres A, Vincent J, Moore, J, Holzer R, Armsby L, Bergersen L. Incidence and Management of Life-Threatening Adverse Events During Cardiac Catheterization for Congenital Heart Disease. Pediatr Cardiol, 2013; epublished. Holzer RJ, Geuvreau K, Kreutzer J, Moore JW,McElhinney DB, Bergersen L. Relationship between procedural adverse events associated with cardiac catheterization for congenital heart disease and operator factors: Results of a multi- institutional registry (C3PO). Catheter Cardiovasc Interv, 2013; epublished. Learn CP, Holzer RJ, Daniels CJ, Torres AJ, Vincent JA, Moore JW, Armsby LB, Landzberg MJ, Bergersen L. Adverse events rates and risk factors in adults undergoing cardiac catheterization at pediatric hospitals—results from the C3PO. Catheter Cardiovasc Interv, 81:997-1005, 2013. Truong UT, Sun HY, Tacy TA. Myocardial Deformation in the Fetal Single Ventricle. J Am Soc Echocardiogr, 26(1): 57-63, 2013. Backes CH, Cua C, Kreutzer J, Armsby L, El-Said H, Moore JW, Gauvreau K,Bergersen L, Holzer RJ. Low weight as an independent risk factor for adverse events during cardiac catheterization of infants. Catheter Cardiovasc Interv, 2013 Feb 22. Kunder R, Kunder C, Sun HY, Berry G, Messner AH, Frankovich J, Roth S, Mark J. Pediatric Plastic Bronchitis: Case Report and Retrospective Comparative Analysis of Epidemiology and Pathology. Case Reports in Pulmonology, Epub 2013 Apr 11. Sun HY, Buccola KJ, Punn R, Silverman NH, Peng L, Perry SB, Balasubramanian S. Transcatheter Device Closure of a Congenital Aortic-Left Atrial Tunnel. Congenital Heart Dis, 2013 Apr 22. Epub ahead of print. EL-Said H, Hegde S, Moore J. First report of atretic coronary sinus stenting in a 5-Kg infant resulting in dramatic improvement of ventricular function in functional single ventricle. Congenit Heart Dis, 2013; epublished. Selamet Tierney ES, Levine JC, Chen S, Bradley TJ, Pearson GD, Colan SD, Sleeper LA, Campbell MJ, Cohen MS, De Backer J, Guey LT, Heydarian H, Lai WW, Lewin MB, Marcus E, Mart CR, Pignatelli RH, Printz BF, Sharkey AM, Shirali GS, Srivastava S, Lacro RV; Pediatric Heart Network Investigators. Echocardiographic methods, quality review, and measurement accuracy in a randomized multicenter clinical trial of marfan syndrome. J Am Soc Echocardiogr, 26(6):657-66, 2013. Molkara D, Tejman-Yarden S, EL-Said H, Moore J. Periocardiocentesis of non-circumferential effusions using non-standard catheter entry sites guided by echocardiography and fluoroscopy. Congenit Heart Dis (in press). EL-Said H, Hegde S, Moore JW. First report of atretic coronary sinus stenting resulting in dramatic improvement of ventricular function in functional single ventricle. Submitted to Congenital heart disease. Congenital Heart Disease April 2013 (accepted). Peng DM, Sun HY, Hanley FL, Olson I, Punn R. Coronary Sinus Obstruction After Atrioventricular Canal Defect Repair. Congenital Heart Dis, 2013 May 20. Epub ahead of print. Sun HY, Boe J, Barth R, Tacy TA. Fetal MRI Correlates with Postnatal CT Angiogram Assessment of Pulmonary Anatomy in Prenatally Diagnosed Tetralogy of Fallot with Absent Pulmonary Valve. Congenital Heart Dis, 2013 May 22. Epub ahead of print. Sun HY, Behzadian F, Punn R, Tacy TA. Decremental left ventricular deformation after pulmonary artery band training and subsequent repair in ventriculoarterial discordance. J Am Soc Echocardiogr, 26(7):765-74, 2013. Longmuir P, Brothers J, de Ferranti S, Hayman L, Van Hare G, Matherne P, Davis C, Joy E, McCrindle B. Promo- tion of Physical Activity for Children and Adults with Congenital Heart Disease: A Scientific Statement from the Atherosclerosis, Hypertension, and Obesity in Youth Committee, Council on Cardiovascular Diseases in the Young, American Heart Association. Circulation, 2013, 217. Tedjasaputra V, Carlos SГЎ R, Arai TJ, Holverda S, Theilmann RJ, Chen WT, Wagner PD, Davis CK, Prisk GK, Hopkins SR. The heterogeneity of regional specific ventilation is unchanged following heavy exercise in athletes. Journal of Applied Physiology, July 2013, 115(1). Nigam V, Srivastava D. Notch 1 represses a default osteogenic pathway in aortic valve mesenchymal cells. JMCC (in press). Szeto K, Pastuszko P, del Alamo JC, Lasheras JC, Nigam V. Bicuspid Aortic Valves Experience Increased Strain As Compared To Tricuspid Aortic Valves. World Journal for Pediatric and Congenital Heart Surgery, 2013. In press, DOI: 10.1177/2150135113501901. Heart Institute heart institute-surgery v5.indd 9 9 1/23/14 4:37 PM CARDIOTHORACIC SURGERY The Pediatric Cardiac Surgery Division of the Division of Cardiothoracic Surgery at the UC San Diego (UCSD) School of Medicine is based at Rady Children’s Hospital-San Diego (RCHSD). The Division, in conjunction with the Division of Pediatric Cardiology, provides cardiovascular surgery services for infants, children and adults with congenital and acquired heart disease. The Division serves the San Diego metropolitan area (population: 3.2 million) and it is a major referral center for Imperial and Orange Counties, Hawaii, New Mexico, Mexico, and the Pacific Rim Islands. Dr. John J. Lamberti is the Joyce and Eugene Klein Director of the Heart Institute at RCHSD and he is Division Chief of Cardiovascular Surgery at RCHSD. Dr. Eric Devaney joined the division on April 1, 2012. Dr. Devaney is an Associate Professor of Surgery at UCSD and he is the Director of Cardiac Transplantation and Cardiac Assist Devices at RCHSD. Dr. Devaney has also assumed the role of Medical Director of Pediatric Cardiac Surgery Critical Care at RCHSD. The Division’s clinical volume for the academic years 20112013 remained steady when compared to previous academic years. The complexity of the caseload has increased due to increasing referrals from outlying areas in Southern California and the State of Hawaii. RCHSD is a “high volume” pediatric cardiac surgical program according to the Society of Thoracic Surgeons (STS) Congenital Heart Surgery Database. The Division’s outcomes are comparable with other leading high volume centers. The STS analysis is based upon risk-adjusted data. The complexity score for RCHSD is slightly higher than the national average reflecting our role as a major referral center. FACULTY John J. Lamberti, MD, Professor of Surgery, Chief of Cardiac Surgery at RCHSD Eugene and Joyce Klein Director of the RCHSD Heart Institute Eric J. Devaney, MD, Associate Professor of Surgery Director of Cardiac Transplantation and Assist Devices at RCHSDDirector of Pediatric Cardiac Surgical Critical Care at RCHSD Peter Pastuszko, MD, Associate Clinical Professor of Surgery (resigned eff. 4/8/2013) heart institute-surgery v5.indd 10 1/23/14 4:37 PM POSTDOCTORAL FELLOWS CLINICAL ACTIVITIES INPATIENT/OUTPATIENT Seemal Mumtaz, MD 2011-2013 The Division of Cardiothoracic Surgery receives referrals from San Diego, Orange and Imperial counties; the Naval Medical Center, San Diego; the San Diego Regional Kaiser Medical Center; Tripler Army Medical Center, Honolulu, Hawaii; Kapiolani Medical Center for Women and Children, Honolulu, Hawaii; Straub Clinic, Honolulu, Hawaii and the Kaiser Permanente Medical Group, Honolulu, Hawaii. The Division’s clinical volume for the academic years 2011-2013 included 514 open-heart, 137 closed-heart and 229 miscellaneous cardiovascular surgical procedures. The faculty provides consultative services at UCSD Medical Center, RCHSD, Sharp Mary Birch Hospital and at all referral sites in Hawaii. In addition, faculty members provide varying levels of support for adult patients with congenital heart disease undergoing treatment at all of the adult hospitals in San Diego County. Dr. John Lamberti and Dr. John Moore organized and coordinated a three day symposium in January 2012. The symposium was entitled “Evolving Concepts in the Management of Complex Congenital Heart Disease III”. The symposium represented the third in a series of biennial meetings designed to address the management of the most complex forms of congenital heart disease. The faculty consisted of multiple experts in surgery and cardiology drawn from the finest programs in North America. RESEARCH ACTIVITIES John J. Lamberti, MD: The Division par- ticipates in multiple longitudinal studies of congenital heart disease sponsored by the Congenital Heart Surgeon’s Society. Dr. Lamberti is the principal investigator on multiple clinical protocols involving complex congenital heart defects. The studies are designed to evaluate the natural history, including before and after surgical therapy, of relatively rare congenital heart defects in a multi-center collaborative effort. Left to Right: John Lamberti, Eric Devaney Heart Institute heart institute-surgery v5.indd 11 11 1/27/14 10:45 AM MAJOR GOALS & PLANS The RCHSD and UCSD Pediatric Cardiology and Cardiovascular Surgery programs are committed to fulfilling our mission to provide optimal care for infants, children and adults born with Congenital Heart Defects and to advance our knowledge and understanding of Congenital Heart Disease. To implement our strategic plan for Cardiac Services we have: 1. successfully completed the recruitment of a third pediatric cardiothoracic surgeon, who is expected to begin operating on site in November 2013. We have recently added additional cardiology faculty with strong expertise in fetal echo and cardiac MRI. 2. funding for and are in the process of physician recruitment for leadership positions in Cardiac Transplantation and Cardiac Critical Care. heart institute-surgery v5.indd 12 3. completed the installation of and are currently actively using a dedicated pediatric Cardiac MRI Scanner and a new state of the art dedicated Pediatric Cardiac Catheterization Laboratory. We are also working in our new cardiac operating room. We have opened a dedicated Cardiovascular Intensive Care Unit (CVICU), and we are on the verge of moving into an expanded, new Heart Center. 4. administrative and Board of Directors approval in place to establish an in-house pediatric heart transplant program associated with the UCSD adult program. We are in process of submitting our UNOS application for cardiac transplantation with the long range goal of adding a program in lung transplantation. 1/23/14 4:37 PM Eric J. Devaney, MD: Dr. Devaney has a strong interest in basic science, clinical research and cardiac transplantation. Dr. Devaney has been instrumental in the creation of a cardiovascular ICU (CVICU) at RCHSD. Dr. Devaney is responsible for the recruitment of personnel and the creation of the infrastructure that will permit RCHSD to begin cardiac transplantation in 2014. Dr. Devaney is a member of the RCHSD Research Council. Basic Science Focus: 1. Sarcomeric basis of contractile dysfunction in heart failure and cardiomyopathy 2. Genetic modification of motor proteins in normal and failing myocytes 3. Analysis of thin filament maintenance in cardiac myocytes Clinical Focus: 1. Clinical applications of assist devices in pediatric heart failure 2. Clinical outcomes in pediatric cardiac surgery Dr. Peter Pastuszko: Dr. Pastuszko is the primary cardiac surgeon involved in an ongoing series of research projects at the University of Pennsylvania in Philadelphia, PA. Dr. Pastuszko travels to Philadelphia five times a year for an intense schedule of experiments designed to evaluate the effects of cardiopulmonary bypass on brain structure and function in a neonatal piglet model. In addition, Dr. Pastuszko collaborated with Dr. Vishal Nigam from the Division of Cardiology on several projects (see publications). DIVISIONAL FACULTY TEACHING ACTIVITIES The cardiac surgeons participate in the following teaching activities: • Dailymorningandafternoonrounds at RCHSD with cardiac surgery fellows, cardiology fellows, ICU fellows, nurses, nurse practitioners, nurses in training, medical students, pediatric residents and cardiology attendings • Biweekly teaching rounds with the PICU team and monthly teaching conferences with the NICU team • Conferences at RCHSD and UCSD Medical Centers including the transplantation conference, adult cardiolo- gy/cardiothoracic surgery conference, pediatric cardiology/cardiothoracic surgery conference and cardiothoracic surgery resident teaching conference • Cardiothoracicsurgeryoutpatientand the Transplant clinics at UCSD and RCHSD • Medical student rotations in CT surgery and Clinical Anatomy. Dr. Lamberti is the mentor, consultant and advisor to the congenital heart surgery program at Kapiolani Medical Center for Women and Children (KMCWC) in Honolulu, Hawaii. KMCWC is the primary pediatric teaching hospital of the John A. Burns School of Medicine Department of Pediatrics at The University of Hawaii/Manoa. Since 1994, Dr. Lamberti has spent five weeks each year at KMCWC assisting in surgery, participating in pre and postoperative care and overseeing quality assurance aspects of the cardiac surgery program. Dr. Lamberti makes teaching rounds every morning during Hawaii Heart Week. He also chairs the peer review committee meeting at KMCWC, and participates in the case review conferences. • Dr. Devaney leads a surgical team on an annual humanitarian teaching mission to Arturo Grullon Children’s Hospital, Santiago, Dominican Republic and Bloom Hospital, San Salvador, El Salvador. AWARDS, HONORS, AND MAJOR PRESENTATIONS John J. Lamberti, MD Castle Connolly, America’s Top Doctors, 2009-2013 San Diego Union Tribune: san Diego Super Doctors 2011-2012 Keynote Speaker, Pediatric cardiac surgery in 2012. Scripps Ranch Auxiliary Event; “Raising the Bar,” Poway, CA, October 12, 2011 Invited Lecture, RCHSD Foundation “The WPO Experience,” two lectures on heart surgery to community leaders. RCHSD ACP Conf. Rm, November 8, 2011 Co-Director of Evolving Concepts in the Management of Complex Congenital Heart Disease III. A Sympsium sponsored by RCHSD, January 19-21, 2012 Invited Presentation, Dilatation of the Aortic Root after Repair of Conotruncal Defects Invited Presentation, Heart Surgery in 2012 at RCHSD. RCHSD Auxiliary Annual Educational Meeting, January 2, 2012 Invited Speaker, Pediatric Cardiac Transplantation. Senior Jurassic Medical Society Meeting at RCHSD, March 1, 2012 Lecturer, RCHSD Cardiac Clinical Nursing Council. Protein Losing Enteropathy, April 13, 2012 Lecturer, Cardiology Core Lecture series (Fellows Conference) at RCHSD. Management of Single Ventricles, May 25, 2012 Invited Debater, Con- The Ross Operation is Better than a Mechanical Valve. Western Society of Pediatric Cardiology, Skamania Lodge, Stevenson, WA, June 8-10, 2012 Keynote Speaker, Pediatric cardiac surgery in 2012. 2nd Annual New Way Golf tournament, the Crosby at Rancho Santa Fe, July 24, 2012 Invited Speaker, North American Society for Cardiovascular Imaging, Pasadena, CA, October 15, 2012 Keynote Address, Surgical Management of Left Ventricular Outflow tract Obstructions Mini debate, Coarctation: The Case for Surgery Visiting Professor, Division of Pediatric Cardiovascular Surgery at The Cardinal Glennon Hospital of St. Louis University, St. Louis, MO. The George Kaiser Lecturer, Pediatric cardiac surgery in 2013, December 4-5, 2012 Participant, Bridgepoint Holiday Bowl Halftime show Celebrating Rady Children’s Hospital, December 27, 2012 Visiting Professor, Divisions of Pediatric Cardiology and Pediatric Cardiac Surgery at the University of Rochester, Rochester, NY, May 29-30, 2013 Invited Lecturer, Future Treatment of Complex Congenital Heart Disease, National Meeting of the Mended Little Hearts Group, Marriott Hotel, Mission Valley, San Diego, CA, June 8, 2013 Keynote Speaker, Pediatric Cardiac Surgery Update. Miracle Mile of Quarters- Kiwanis Club, San Diego, CA, June 12, 2013 Heart Institute heart institute-surgery v5.indd 13 13 1/23/14 4:37 PM Research Support Grant/Contract Grant/Contract # # Annual Budget Paul David Grossfeld, MD Marfan Trial NHBLI/National Marfan Foundation $50,000 per year Feb. 2009-Feb. 2014 Children’s Heart Foundation $75,000 per year Jan. 2011-Dec. 2013 Identification of Genes for Cognition in Distal 11q: Further Genotyping 2009-PEDGENO $75,000 June 2009-Dec. 2009 Vishal Nigam, MD Mechanisms Of Notch1 In Aortic Valve Calcification Nih/Nhlbi/7 K08hl086775-03 $85,000 Oct. 2009-Apr. 2012 AGA Medical Corporation ADO II Clinical Study $432,567 Dec. 2008-Indefinite John Moore, MD STARFlex in Atrial Septal Defect- Long term Status Assessment of Patients Following Closure of ASD with the STARFlex Septal Occlusion System in IDE Study G-960098 (SALSA)/NMT MEDICAL, INC. $2,900 Aug. 2007-Indefinite Coarctation of the Aorta Trail (COAST) Johns Hopkins University $198,865 Sept. 2007-Indefinite Closure of Muscular Ventricular Septal Defects with the Amplatzer Muscular VSD Occluder-Post Approval Study (Muscular VPA) AGA Medical Corporation $26,600 Sept. 2008-Indefinite Eric Devaney, MD NIH K08 Mentored Scientist Award $620,000 2009-2014 Invited Discussant, Western Thoracic Surgical Association 39th Annual meeting, Coeur d’Alene, ID, June 26-29, 2013. Oral presentation #12: Transposition of the Great Arteries and Intact Ventricular Septum-Outcomes and Time Interval of Early Repair. Authors: Woods RK, Trapp K, Simpson PM, Cao Y, Ghanayem NS, Twedell JS, from Milwaukee Children’s Hospital Invited Speaker, The CVICU. 2014 Charity Ball Committee Meeting, RCHSD, MOB 113, September 18, 2013 14 Total DirectTotal Dollars/ Direct Dollars Duration ofDuration Grant of Grant Eric J. Devaney, MD Results of Second Stage Palliation of Single Ventricle Heart Disease. 39th Annual ODICH Society Conference, Cleveland, OH, May 13-14, 2011 Cardiac Surgical Management of the LowBirth Weight Infant. Evolving Concepts in the Management of Complex Congenital Heart Disease, San Diego, CA, January 19-21, 2012 PUBLICATIONS Dr. Lamberti’s Publications Colasacco C, Peterson BP, Worthen M, Lamberti JJ and Spear R. Near infrared spectroscopy (NIRS) to predict post-operative renal insufficiency following repair of congenital heart disease. World Journal for Pediatric and Congenital Heart Surgery, 2(4): 536-540, 2011. Davis CD, Pastuszko PP, Lamberti JJ, Moore JM, Hanley FL and EL-Said H. The hybrid procedure for the borderline left ventricle. Cardiol Young, 21:2630, 2011. Heart Institute heart institute-surgery v5.indd 14 1/23/14 4:37 PM ars t EL-Said H, Hamzeh R, Lamberti J, Moore J. Catheter balloon adjustment of the pulmonary artery band: Feasibility and safety. Pediatr Cardiol, 32:8-16, 2011. Punn R, Lamberti JJ, Balise RR and Seslar SP. QTc prolongation in pediatric patients following congenital heart disease surgery. Cardiol Young, 21:400410, 2011. Tabbutt S, Jacobs M, Ohye RG, Goldberg C, Morell VO, Hanley FL, Lamberti JJ and Jacobs JP. Can randomized clinical trials impact the surgical approach for hypoplastic left heart syndrome? World Journal for Pediatric and Congenital Heart Surgery, July 2011 vol. 2, no. 3, 445-456. Hannan EL, Cozzens KS, Samadashvili JN, Morley JN, Williams RG, Kulik TJ, Bierman FZ, Ruiz CE, Alfieris GM, Lamberti JJ Jr., Gold JP. Regulatory efforts to assess and improve the quality of pediatric cardiac surgery in New York State. Progress in Pediatric Cardiology, 32;(2): 111-119, 2011. Rao RP, Connolly D, Lamberti JJ, Fripp R, El Said H. Transverse Aortic Arch to Descending Aorta Ratio: A New Echocardiographic Parameter for Management of Coarctation of the Aorta in the Newborn. Congenital Heart Disease, 7(2): 160-169, 2012. Book Chapters Pastuszko P, Lamberti J. Coarctation. In: Cardiothoracic Surgery Review. Kenneth L. Franco and Vinod H Thourani, Editors. 2011 Lippincott Williams and Wilkins, pp. 1588-1592. Mainwaring RD, Lamberti JJ. Congenital anomalies of the Mitral Valve. Pediatric Cardiac Surgery, Fourth Edition (Editors: C.E. Mavroudis and C. Backer) 2013 John Wiley &Sons/Blackwell, Hoboken, NJ, pp. 640-658. Brief Publications Lamberti JJ. Invited Editorial. In: J. Am. Coll. Card. Aortic arch obstruction after the Norwood procedure for hypoplastic left heart syndrome: Is is inevitable? Is it preventable? JACC, 58:877-879, 2011. Dr. Pastuszko’s Publications Mammen A, Kubin J, Greeley WJ, Schears GJ, Pastuszko P, Wilson DF and Pastuszko A. Effect of hypoxia on expression of selected proteins involved in regulation of apoptotic activity in sriatum of newborn piglets. Neurochem Res, 36:746-53, 2011. Pirzadeh A, Schears G, Pastuszko P, Liu H, Kubin J, Reade E, Mendoza-Paredes A, Greeley W, Nadkarni V, Wilson DF, Pastuszko A. Effect of deep hypothermic circulatory arrest followed by cardiopulmonary bypass on brain metabolism in newborn piglets: Comparison of pH-stat and Alpha-stat management. Pediatr Crit Care Med, 12(2):e79-86, 2011. Davis CK, Pastuszko P, Lamberti JJ, Moore J, Hanley F, El Said H. The hybrid procedure for the borderline left ventricle. Cardiology in the Young, 21, pp. 26-30, 2011. Pastuszko P, Schears GJ, Pirzadeh A, Kubin J, Greeley WJ, Wilson DF, Pastuszko A. Effect of Granulocyte-Colony Stimulating Factor on Expression of Selected Proteins Involved in Regulation of Apoptosis in the Brain of Newborn Piglets after Cardiopulmonary Bypass and Deep Hypothermic Circulatory Arrest. J Thorac Cardiovasc Surg, 143, pp. 1436-1442, 2012. Dr. Devaney’s Publications Morales DL, Almond CS, Jaquiss RD, Rosenthal DN, Naftel DC, Massicotte MP, Humpl T, Turrentine MW, Tweddell JS, Cohen GA, Kroslowitz R, Devaney EJ, Canter CE, Fynn-Thompson F, Reinhartz O, Imamura M, Ghanayem NS, Buchholz H, Furness S, Mazor R, Gandhi SK, Fraser CD, Jr. Bridging children of all sizes to cardiac transplantation: the initial multicenter North American experience with the Berlin Heart EXCOR ventricular assist device. J Heart Lung Transplant. 30(1):1-8, 2011. Hoashi T, Bove EL, Devaney EJ, Hirsch JC, Ohye RG. Outcomes of 1(1/2)or 2-ventricle conversion for patients initially treated with single-ventricle palliation. J Thorac Cardiovasc Surg. 141(2):419-424, 2011. Hoashi T, Bove EL, Devaney EJ, Hirsch JC, Ohye RG. Intermediate-term clinical outcomes of primary biventricular repair for left ventricular outflow tract obstruction and ventricular septal defect. J Thorac Cardiovasc Surg. 141(1):200-206, 2011. Dinh, DC, Gurney, JG, Donohue, JE, Bove, EL, Hirsch, JC, Devaney, EJ, Ohye, RG. Tricuspid valve repair in hypoplastic left heart syndrome. Pediatr Cardiol, 32(5):599-606, 2011. Lee TM, Aiyagari R, Hirsch JC, Ohye RG, Bove EL, Devaney EJ. Risk factor analysis for second stage palliation of single ventricle anatomy. Ann Thorac Surg, 93(2):614-9, 2012. Fraser CS, Jaquiss RD, Rosenthal DN, Humpl T, Canter CE, Blackstone EH, Naftel DC, Ichord RN, Bomgaars L, Twedell JS, Massicotte MP, Turrentine MW, Cohen GA, Devaney EJ, Pearce FB, Carberry KE, Kroslowitz, R, Almond CS. Prospective trial of a pediatric ventricular assist device. N Engl J Med, 367(6):532-41, 2012. Kavarana MN, Riley M, Sood V, Ohye RG, Devaney EJ, Bove EL, Hirsch JC. Extended single-patch repair of supravalvar aortic stenosis: a simple and effective technique. Ann Thorac Surg. 93(4):1274-8, 2012. Book Chapters Devaney EJ, Bove EL. Congenitally Corrected Transposition of the Great Arteries. In: Mavroudis C and Backer CL, eds. Pediatric Cardiac Surgery, 4th edition. West Sussex, Wiley Blackwell, 2013: 530-541. Hirsch JC, Devaney EJ, Ohye RG, Bove EL: Hypoplastic Left Heart Syndrome. In: Mavroudis C and Backer CL, eds. Pediatric Cardiac Surgery, 4th edition. West Sussex, Wiley Blackwell, 2013: 619-635. Heart Institute heart institute-surgery v5.indd 15 15 1/23/14 4:37 PM Maternal Fetal Medicine Physicians of the Maternal-Fetal Medicine Division of Rady Children’s Specialists of San Diego (RCSSD) have been providing prenatal diagnosis, ultrasound imaging, consultation, and pregnancy care to families and physicians in San Diego, Imperial, and Riverside Counties since 1990. The Division continues to focus on: 1. Expanding clinical activities. 2. Recruiting, and 3. Increasing our CME outreach. Clinical Activities. Our inpatient service is at Sharp Mary Birch Hospital for Women, and the outpatient offices are in the Frost Street complex adjacent to the Sharp/Rady Children’s Campus, as well as in Encinitas, Murrieta, San Ysidro, and Grossmont Hospital. The group’s consultation and outpatient volume continues to increase; we project that we will perform over 15000 ultrasound examinations, over 700 fetal echocardiogram, and nearly consultations this year. The group continues to limit our delivery volume to 500-700 deliveries per year. Recruiting. The Division of Maternal Fetal Medicine welcomed Dr. Tevy Tith in August, 2013. Dr. Neha Trivedi, who joined us in September 2011, will be leaving us for Kaiser this year, and we are in the process of recruiting a replacement for her. CME. The Division continues to sponsor a yearly High Risk Obstetrics course each fall, and a Prenatal Diagnosis course each spring or early summer. Registration numbers have risen each year. Our 2013 Prenatal Diagnosis Course, at Scripps Schaetzel Center on May 31/June 1, attracted over 200 participants, and we are in the final planning stages for our High Risk OB course, which will be on November 2 at the TriCity Hospital. mfm v5.indd 16 1/27/14 1:57 PM FACULTY Val Catanzarite, MD, PhD, Division Chief Joanna Adamczak, MD Holly Casele, MD Larry Cousins, MD Sean Daneshmand, MD Wade Schwendemann, MD Tevy Tith, MD Neha Trivedi, MD Tevy Tith, MD, joined the Division in Au- gust, 2013. She received her undergraduate education at University of California, Berkeley, and then completed Medical School at UCSD, Residency in Obstetrics and Gynecology at UCLA, and Fellowship in Maternal Fetal Medicine at UC Irvine in July of 2013. Dr. Tith’s major clinical interests include prenatal diagnosis, especially prenatal diagnosis of congenital heart defects, and diagnosis and medical/surgical management of acute maternal morbidities. Academic honors include Charles Kimball Award for Best Poster at the 2009 Pacific Coast Obstetric and Gynecologic Society. Research projects during fellowship included: • Maternal serum cytokine levels and angiogenic factor levels in singleton pregnancies conceived with assisted reproductive technology versus spontaneously conceived pregnancies. • Post-Cesarean hyperglycemic control in Diabetic pregnancies and subsequent maternal complications • Differential VEGF splicing in normal pregnancies and pregnancies complicated by adverse outcomes LEFT TO RIGHT: Val Catanzarite, Holly Casele, Wade Schwendemann, Joanna Adamczak, Larry Cousins, Tevy Tith, Sean Daneshmand Maternal Fetal Medicine mfm v5.indd 17 17 1/27/14 10:48 AM Dr. Tith is a member of the American Congress of Obstetrics & Gynecology, Society for Maternal Fetal Medicine, and Society for Gynecologic Investigation. She serves as a reviewer for the American Journal of Obstetrics and Gynecology. Dr. Tith speaks Cambodian and Spanish fluently. Joanna Adamczak, MD, received her undergraduate training at the University of California, Santa Barbara, followed by medical school at St. Georges University and Obstetrics and Gynecology Residency at St. Barnabus Medical Center in Livingston, New Jersey. Her fellowship training was at Robert Wood Johnson Medical Center and the University of Pennsylvania. Academic honors include Dean’s Honor Roll in medical school, and election as a resident representative to the Committee on Resident Education in Obstetrics in Gynecology/Association of Professors of Gynecology and Obstetrics (CREOG/APGO). She has bee active in the Crudem Foundation for Haiti Medical /Surgical Relief. During her fellowship Dr. Adamczak achieved certification in Fundamental Critical Care by the Society of Critical Care Medicine. Clinical interests include prenatal care for women with complex medical complications including maternal cardiac disease, organ transplants and cancer, and Dr. Adamczak also has a strong interest in prenatal diagnosis. She is the fourth memberofourDivisiontoprovideCVS. Dr. Adamczak is fluent in Polish and speaks Spanish as well. Holly Casele, MD received her undergraduate degree magna cum laude from Brown University, followed by medical school and residency at Northwestern University, where she was elected into the Alpha Omega Alpha Honor Medical society. She then completed a fellowship at the University of Pittsburgh, Magee-Women’s Hospital. She was an Assistant Professor at Northwestern University Medical School and a senior attending at the Evanston Hospital in Evanston, Illinois from 1997-2005, before joining our group. She has been elected as one of 18 mfm v5.indd 18 America’s Best Doctors every year from 2007 to 2010 and again in 2013. Dr. Casele’s clinical interests include thrombophilias and thromboembolic disorders in pregnancy, a topic upon which she has written and lectured widely; recurrent pregnancy loss, and noninvasive screening for fetal aneuploidy. Dr. Casele is certified for chorionic villus sampling. Dr. Casele is currently a co-principal investigator for a study assessing the accuracy of a noninvasive screening tool for Down syndrome and other aneuploidy detections. She was instrumental in bringing our ultrasound image storage/ reporting system online, and has been involved in the implementation of our Epic electronic medical record system as well. Larry Cousins, MD was a founding member of the Maternal-Fetal Medicine Division. His undergraduate education was at UCLA, followed by medical school and residency at Creighton University, and fellowship at the Harbor/UCLA Program. Subsequently, Dr. Cousins taught at the University of California, San Diego (UCSD) and Loma Linda University, and is a founding member of the Maternal Fetal Medicine group here. Clinical interests include medical complications of pregnancy, particularly diabetes, and preterm birth prevention. He has been very active at Sharp Mary Birch Hospital for Women, where is currently a member of the ObGyn supervisory committee. He served as Director of Maternal-Fetal Medicine at Sharp and Co-Chair of the Women and Infants Research Forum since 1991, Co-Chair of the Perinatal Morbidity and Mortality Committee since 2004, and Chief of Staff at Sharp Mary Birch in 2008-2009. Dr. Cousins was honored with the Sharp HealthCare Core Award for Quality Pillar for his work with the Cerner Design Team in 2009, and received a commendation from Sharp Mary Birch for Perinatal Special Care Unit Teaching in 2009 as well. He has been selected as one of America’s Top Doctors again in 2013. Sean Daneshmand, MD received his undergraduate degree from the UCSD, completed medical school at New York Medical College in Valhalla, New York, residency at UCLA, and fellowship at UCSD, before joining the Maternal-Fetal Medicine Division in 2002. Dr. Daneshmand has basic science interests in the underlying triggers for preterm labor, preterm rupture of the membranes, and preeclampsia. Major clinical interests include surgical complications of pregnancy and in particular management of invasive placentation. Dr. Daneshmand has also been very active in fundraising for families with premature babies through Miracle Babies, a nonprofit organization which he founded in2008.MiracleBabies’activitiesin2013 included numerous charity events and a run/walk that attracted >1500 participants. Under Dr. Daneshmand’s guidance, the Miracle Babies foundation recently received a substantial grant award for study of obesity in pregnancy. He has also been selected by the San Diego County Medical Society for Top Doctors honors. Dr. Daneshmand speaks Farsi and conversational Spanish. Wade Schwendemann, MD joined the Maternal-Fetal Medicine Division in 2009. Dr. Schwendemann was a cum laude graduate of Albion College in Michigan, then completed medical school at the Medical College of Ohio in Toledo, Ohio, residency at the University of Kentucky, and fellowship at the Mayo Clinic in Rochester, Minnesota. Dr. Schwendemann has particular interests in simulation tools for teaching in maternal-fetal medicine, and in the clinical arenas of prenatal diagnosis and management of multiple gestations. Dr. Schwendemann provides chorionic villus sampling services for early prenatal diagnosis. Dr. Schwendermann as involved with development of the residency curriculum while at Mayo Clinic, including modules for preeclampsia/eclampsia/HELLP syndrome, and teaching of amniocentesis. He is currently working with the blood bank and American Red Cross to augment blood banking services in San Diego, with particular interest in the potential for public cord blood banking, and is a member of the Board of Directors for the blood bank. Maternal Fetal Medicine 1/23/14 4:40 PM Neha Trivedi, MD, received her under- graduate training at the University of California, Los Angeles, and medical education at the University Of Pittsburg School Of Medicine, and then completed both Obstetrics and Gynecology Residency and Maternal Fetal Medicine Fellowship training at the University of California, San Diego. Academic honors include Magna Cum Laude and Neurosciences Departmental Honors while at UCLA, Alpha-Omega-Alpha honors, the University of Pittsburg Humanism award in 2004, and an HIV/AIDS Education Leadership Award while in medical school, Dr. Trivedi also received the Berlex Resident Teaching Award during residency. Dr. Trivedi has basic science interests in microRNAs in early mammalian development. Her clinical interests include diabetes in pregnancy, biochemical markers in prediction of pregnancy outcomes, trauma in pregnancy, and prenatal diagnosis. Dr. Trivedi speaks Spanish and conversational Gujarti and Hindi. Val Catanzarite, MD, PhD received his undergraduate education at the California Institute of Technology, medical school at UCSD and a PhD in Biophysics at UC Berkeley, with thesis research in the field of medical artificial intelligence. He went on to residency at Stanford University Medical Center and fellowship at the University of New Mexico. He taught at UNM and the University of Arkansas before returning to San Diego in 1989. Dr. Catanzarite is a founding member of the Maternal-Fetal Medicine Division. Dr. Catanzarite has a longstanding interest in continuing medical education, including computer based instruction. Clinical interests include critical care in obstetrics, prenatal diagnosis, diagnosis and management of cardiac abnormalities of the fetus, identification and management of vasa previa, surgical and medical prevention of preterm birth, and emergency response teams in obstetrics. Dr. Catanzarite has served as Codirector of the Sharp/Rady Children’s Prenatal Diagnostic Center since 1991, and chairs the Sharp Mary Birch Pharmacy, Nutrition and Therapeutics Committee. mfm v5.indd 19 MAJOR GOALS & PLANS Clinical Activities. • Frost Street Site. We moved into new office space at 7910 Frost Street, and increased the capacity of our prenatal diagnostic center on the central campus by 20%. • North County Coastal. In 2012, we moved our North County Coastal office to the Sanford Clinic in Vista. We will soon offer inpatient consultations at TriCity Medical Center. • Grossmont Hospital. We increased capacity at our Grossmont site by 33% this year, and anticipate expanding availability of fetal echocardiography at Grossmont during the fourth quarter of 2013. • South Bay. We are developing an additional site on the Sharp Chula Vista campus and increasing capacity at our San Ysidro site. Research. We anticipate wrapping up ongoing projects (outlined above), and will soon submit a research protocol for a retrospective series of cases of prenatal diagnosis, obstetric and surgical management and maternal/fetal outcomes of invasive placentas. Education: Rady and Arrowhead Medical Center are finalizing an agreement that will bring Maternal Fetal Medicine fellows to our centers for training starting in 2013 or early 2014. Our major CME events for 2013-14 will be a fall High Risk OB Course, which will be presented on the TriCity Hospital campus, and a spring Prenatal Diagnosis course. This year, we will update our website (sandiegoperinatal.com) and improve/revise our library of patient information and resources on that site. 1/27/14 9:53 AM Dr. Catanzarite organizes the Division’s monthly ultrasound and prenatal diagnosis conferences, and, has been course coordinator for our High Risk OB and Prenatal Diagnosis courses. He has also been selected by the San Diego County Medical Society for Top Doctors honors. Dr. Catanzarite ran his 44th marathon in 2011, and recently published a book, Train Insane: Developing a lifelong plan for ultimate fitness. Dr. Catanzarite speaks conversational Spanish and Russian, and reads German and French. Since 2011, he has been working on TORFL certification in Russian, and hopes to establish international CME courses in collaboration with colleagues in Kiev, Ukraine. RESEARCHACTIVITIES Joanna Adamczak, MD • (WithothersintheDivision):Prenatal diagnosis, obstetric management, and neonatal outcomes in vasa previa) Holly Casele, MD • (WithothersintheDivision):Prenatal diagnosis, obstetric management, and neonatal outcomes in vasa previa) Val Catanzarite, MD, PhD • (WithothersintheDivision):Prenatal diagnosis, obstetric management, and neonatal outcomes in vasa previa • (With others in the Division): Fetal anemia:Acomprehensivereview. • (With others in the Division): OB Team Stat at Sharp Mary Birch: the first five years. • (WithothersfromOBAnesthesiaand PediatricSurgery):VACTERLinpregnancy:Areviewofmanagementissues Larry Cousins, MD • Intra-amniotic infection assessment tools • (WithothersintheDivision):Prenatal diagnosis, obstetric management, and neonatal outcomes in vasa previa. Sean Daneshmand, MD • (WithothersintheDivision):Prenatal diagnosis, obstetric management, and neonatal outcomes in vasa previa. 20 mfm v5.indd 20 Wade Schwendemann, MD • (With others in the Division): Fetal anemia:Acomprehensivereview. • (WithothersintheDivision):Prenatal diagnosis, obstetric management, and neonatal outcomes in vasa previa. MAJORPRESENTATIONS Bird LM, Catanzarite V, Shea TJ, Willert JR. The Association Of Alpha-Thalassemia With Congenital Anomalies. David W. Smith Workshop on Malformations and Morphogenesis, Philadelphia, PA, August 2009 Cousins L. Natural progesterone administration and the risk of medical complications of pregnancy: secondary analysis from a multinational, randomized, double blind, placebo controlled trial. Society for Maternal-Fetal Medicine Annual Meeting, San Diego, CA, 2009 Schwendemann W. A Simulation Model for Fetoscopic Laser Photocoagulation; Society for Maternal-Fetal Medicine Annual Meeting, San Diego, CA, 2009 Schwendemann W. VitaminCdoesnot prevent ROS-mediated Syncytin expression or trophoblast differentiation. Society for Maternal-Fetal Medicine Annual Meeting, San Diego, CA, 2009 Schwendemann W. (1) Cervical models to teach interns accurate dilatationandeffacementassessmentskills during pregnancy; (2) Improvement in Breast Exam Skills During an Intern Training Program; (3) Changes to the PRIMER (Procedural Centered Repetition Involving Montessori-type Experience and Rehearsal) Program. CREOG/ APGO Annual Meeting, San Diego, CA, 2009 Trivedi N, Phan, J Woelkers D. Urine Sample Characteristics Do Not Affect Measurement of Urinary sFlt-1 or PlGF. Society of Maternal Fetal Medicine, 2009 Annual Meeting, San Diego, CA, January 2009 Trivedi N, Valencia M, Basu T, Fortlage D, Bansal V, Ramos G, Kelly T, Coimbra R. Radiation Exposure in the PregnantTraumaPatient:Implications for Fetal Risk Counseling. Society of Maternal Fetal Medicine, 2009 Annual Meeting, San Diego, CA, January 2009 Adamczak J, Critical Care Symposium: case presentation, Society of Maternal Fetal Medicine, 2009 Annual Meeting, San Diego, CA, January 2009 Trivedi N, Valencia M, Bansal V, Kelly T, Coimbra R, Moore T. The Predictive ValueofInjurySeverityScoreonOutcomes of Pregnant Trauma Patients. American College of Obstetrics & Gynecology, 2009 Annual Meeting, Chicago, IL, May 2009 Trivedi N, Tarsa M, Hartney C, Levy D, Anton T, Pretorius D. Congenital Cardiac Lesions: Prenatal Reading vs Outcomes. American Institute of Ultrasound in Medicine, New York, NY, April 2009 Trivedi N, Guo G, Robson P, Laurent L. Do MicroRNAs play a role in early embryogenesis in Dicer 1-null mice? Society for Maternal Fetal Medicine Annual Meeting, Chicago, IL February 2010 Trivedi N, Wen E, Aguayo J, Tolen J, Agent S, Ramos G, Moore TR. Impact of Diagnostic Intervals in Gestational Diabetes on Glycemic Control and Pregnancy Outcomes. Society of Gynecologic Investigation Annual Meeting, Orlando, FL, March 2010 Trivedi N, LaCoursiere Y, Wen E, Aguayo J, Tolen J, Ramos G. The Impact of Depressed Mood on Glycemic Control and Pregnancy Outcomes in Women with Diabetes. Society for Gynecologic Investigation Annual Meeting, Orlando, FL, March 2010 Trivedi N, Liao X, Guo G, Robson P, Liao X, Laurent L. The role of microRNAs in early mammalian development. International Society for Stem Cell Research Annual Meeting, San Francisco, CA, June 2010 Adamczak J. Maternal Height is independently associated with Cesarean delivery. Poster presented at 2010 American College of Obstetrics and Gynecology Annual Meeting Gambling DR, Catanzarite VA, Partridge BA. Obstetric and Anesthetic Management of a Parturient with VACTERL Syndrome. Poster presentation, 2013 SOAP 45th Annual Meeting, San Juan, PuertoRico,April24-28,2013 Maternal Fetal Medicine 1/23/14 4:40 PM Tith T. Diabetes, Pregnancy, and the Heart. The Orange County Diabetes Collaborative Conference. 7th Annual Event, Children’s Hospital of Orange County. April 2013 Tith T. Thromboprophylaxis in the Post-Cesarean Patient. Current Controversies in Maternal Fetal Medicine. Welsches, OR, August 2012 Tith T. Thromboprophylaxis in the Morbidly Obese Patient. Current Issues in Perinatal Medicine. Palm Springs, CA, September 2012 Tith T, Rastegar I, Holschneider HH, Axtell A. Peak Postoperative Glucose Is A Predictor of Postoperative Complications in Patients Undergoing Major Gynecologic Surgery. October 2009 Tith T, Rastegar I, Holschneider HH, Axtell A. Postoperative Glucose Is A Predictor of Postoperative Complications in Patients Undergoing Major Gynecologic Surgery. Poster presented at ACOG, San Francisco, CA, May 2009 Zhang HH, Wang YP, Tith T, Chen DB. Analysis of Nitroso-Proteomes In Normotensive and Severe Preeclamptic Placentas. Poster presented at Society for Gynecologic Investigation, Miami, FL, March 2012 Tith T, Wang W, Hachey S, Hodges JK, Chen DB. Differential VEGF mRNA Splicing In Preeclampsia And Normal Human Placentae. Poster presented at Society for Gynecologic Investigation, San Diego, CA, March 2012 Tith, T, Wen Wang, Deborah A. Wing, John Kingdom, Dongbao Chen. DifferentialVEGFmRNASplicingin Preeclampsia and Normotensive Human Placentas. Poster submitted for Society for Gynecologic Investigation, Orlando, FL, March 2013 Bastek JA, Langmuir H, Kondapalli LA, ParГ© E, Adamczak JE, Srinivas SK. Is the administration of corticosteroids costeffectiveforlatepreterminfants? A decisioanalytic and economic analysis. Oral presentation at SGI 2012 Adamczak JE. Direct Measurements of Cervical Remodeling for Predicting Preterm Birth. The Cervix Study, poster presentation at SMFM 2012 PUBLICATIONS Casele HL. The use of unfractionated heparin and low molecular weight heparins in pregnancy. Clinical Obstetrics and Gynecology, 49(4):895905, 2006. Casele HL, Grobman W. Cost Effectiveness of thromboprophylaxis with intermittent pneumatic compression at cesarean delivery. Obstet Gynecol, 108(3):535-40,2006. Duhl AJ, Ural SH, Branch W, Casele HL, Cox-Gill J, de Veciana M, Hamersley, SL, Hyers TM, Katz V, Kuhlman R, Nutescu EA, Paidas M, Thorp JA, Zehnder JA, for the Pregnancy and Thrombosis Working Group. Am J Obstet Gynecol,197(5):457,2007. Catanzarite V, Hilfiker M, Daneshmand S, Willert J. Prenatal diagnosis of fetal hepatoblastoma: Case report and review of the literature. J Ultrasound Med,27(7):1095-8,2008. Schwendemann WD, O’Brien JM, Barton JR, Milligan DA, Istwan N. Modifiable risk factors for growth restriction in twin pregnancies. Am J Obstet Gynecol.192(5):1440-2,2005. Schwendemann WD, Contag SA, Wax JR, Miller RC, Polzin WJ, Koty PP, Watson WJ. Sonographic findings in trisomy 9. J Ultrasound Med, 28(1):3942, 2009. Nitsche JF, McWeeney DT, Schwendemann WD, Rose CH, Davies NP, Watson W, Brost BC. In-utero stenting: Development of a low-cost high-fidelity task trainer. Ultrasound Obstet Gynecol, 34(6):720-3,2009. Schwendemann WD, Contag SA, Koty PP, Miller RC, Devers P, Watson WJ. Ultrasound findings in trisomy 22. Am J Perinatol,26(2):135-7,2009. Nitsche JF, McWeeney DT, Schwendemann WD, Rose CH, Davies NP, Watson W, Brost BC. In-utero stenting: development of a low-cost high-fidelity task trainer.Ultrasound Obstet Gynecol, 34(6):720-3,2009. Trivedi N, Ylagan M, Moore TR, Bansal V,WolfsonT,FortlageD,CoimbraR, Kelly T. Predicting Major Outcomes Following Trauma in Pregnancy. Submitted to British Journal of Obstetrics & Gynaecology. Trivedi N, Tarsa M, Hartney C, Levy D, Anton T, Pretorius D. Congenital Cardiac Lesions: Prenatal Reading vs Outcomes. Journal of Ultrasound Medicine, in press 2011. Ludmir J, Adamczak J, Schwartz N. In: Gabbe:Obstetrics: Normal and Problem Pregnancies, 6th ed Book chapter, Surgical Procedures in Pregnancy, 2010. Adamczak J. Oyelese Y, Tobon L, Burton A, Ashkinadze E, Canterino J, Smulian J. The significance of a positive second trimester serum screen for Trisomy 18. The Journal of Maternal-Fetal & Neonatal Medicine, in press 2011. Gambling DR, Catanzarite V, Fisher J, Harms L: Anesthetic management of a pregnant woman with GorhamStout disease. Int J Obstet Anesth, 20:85-8,2011. Munden A, Butschek R, Poeltler D, Krohne S, Tom W, AliГі A. Ritter M, Catanzarite, VA, Mendoza, A, Smith, D, Friedlander, M, Friedlander, S: A prospective longitudinal study documenting the incidence of infantile hemangiomas and their association with placental anomalies. Submitted for publication 2011. Cousins LM, Poeltler DM, Faron S, Catanzarite V, Daneshmand S, Casele H. Nonstress testing at ≤ 32.0 weeks’ gestation:arandomizedtrialcomparingdifferentassessmentcriteria.Am J Obstet Gynecol, 207(4):311.e1-7,2012. Tith T, Rapkin A. Chronic Pelvic Pain of EnterocolicOrigin.In:Chronic Pelvic Pain. Oxford: Wiley-Blackwell Publishing, 2011. In Submission: Chen DB, Zhang HH, Feng L, Wang W, Satohisa S, Tith T. S-nitrosylation of cofilin-1 via eNOS derived NO is a novel pathway for estradiol-17-induced endothelial cell cytoskeleton remodeling. Hypertension, 2013. Maternal Fetal Medicine mfm v5.indd 21 21 1/23/14 4:40 PM Neurosurgery Rady Children’s Specialists San Diego’s (RCSSD) Neurosurgery Division has had a tremendously successful year, expanding its clinical activities and research, training the next generation of pediatric neurosurgeons, and continuing to broaden its national and international impact on neurosurgical care. Thanks to philanthropy and to the commitment of RCHSD physicians, nurses, staff and volunteers, we are able to provide the best neurosurgical care available to all children. The Division of Neurosurgery is among the most respected centers in the United States. The Division provides pediatric surgical evaluation, surgery and pre-operative and post-operative care for disorders of the brain, spine and peripheral nerves. Among the conditions treated are cerebrovascular malformations, surgical treatment for epilepsy, peripheral nerve disorders or injuries, brain and spinal cord tumors, cerebrospinal fluid diversion, and craniofacial diseases. From July 2011 to June 2012, RCSSD’s Pediatric Neurosurgeons performed over 600 surgeries, including procedures for Brain Tumors (15%) including 17 skull base and 8 transsphenoidal approaches, Spinal Cord Tumors (3%), and CSF Diversion or shunting procedures (10%) consisting of Revisions (6%), Insertions (6%), Lumbar to Peritoneal Shunts (0.2%), and Reservoir Placement (0.5%). Our current infection rate for CSF diversion is < 2.0%. Other approaches included, Craniofacial Procedures (15%: 80% Open and 20% Endoscopic), Epilepsy Surgery 6% (25% resective surgery and 75% VNS), Congenital Anomalies (Chiari Malformations 3%, Closed Neural Tube Defects 3%, Open Neural Tube Defects 1%, and Encephaloceles 1%), Intracranial Cysts (5%), Brachial Plexopathies (0.7%), and Vascular Anomalies (5%). Other cases included Skull Tumors (5%), Endoscopic Third Ventriculostomy (5%), and Trauma Related Cases (5%) with 42 Intracranial Monitor Placements. The overall infection rate was < 2%. Operative Case Duration was mean 1.9 + 1.2 hours (Range 17 minutes to 8.05 hours) with a MODE of 2 hours. 65% of the procedures were graded as significant intracranial or spinal interventions. We continue to offer tertiary care services for some of the county’s most complex cases, including cerebrovascular disease, skull base surgery, and minimally invasive endoscopic approaches. We continue to have one of the largest practices for tumors in the United States. Combined craniofacial and neurological surgery cases continue to increase from 2003 to the present. A number of patients present from National and International Referrals. There has been significant growth in the Spasticity and Epilepsy Programs to date. The Pediatric Vascular Service remains one of, if not the, busiest in the world. neurosurgery v4.indd 22 1/23/14 4:42 PM FACULTY Michael L. Levy, MD, PhD, FACS, FAANS Professor and Head, UCSD RCHSD Division of Pediatric Neurosurgery Hal S. Meltzer, MD Professor, UCSD RCHSD Division of Pediatric Neurosurgery John R. Crawford, MD Professor, UCSD RCHSD Division of Pediatric Neurology Director of NeuroOncology Program Justin M. Brown, MD Assistant Professor and Head of Brachial Plexus and Peripheral Nerve Surgery, UCSD RCHSD Division of Pediatric Neurosurgery Alexander A. Khalessi, MD, MS Assistant Professor and Head of Pediatric Vascular and Endovascular Surgery, UCSD RCHSD Division of Pediatric Neurosurgery Melissa A. Griffin RN, MSN, PNP Pediatric Neurosurgical Nurse Practitioner Neurosurgical Teams To maximize our ability to care for our patients, multispecialty approaches to complex neurosurgical issues have been developed. To date these include: Neural Tube Defects Team The Neural Tube Defects Clinic at RCHSD provides a comprehensive management approach to children and young adults with Neural Tube Defects, both open and closed. The Clinic Team includes Medical Directors Hal S. Meltzer, MD and Andrew Skalsky, MD (Director of Physiatry and the Pediatric Rehabilitation Program). It is composed of the specialties of Neurosurgery, Orthopedics, Urology, Pediatric Surgery, Physiatry, Nursing, Enterostomal Therapy, Physical Therapy, Occupational Therapy, Genetic Counseling, and Social Work. The clinic ensures that all patients can be seen by multiple subspecialties and makes available diagnostic and evaluative services, telephone consultation for families and professionals, patient/ family education in Spina Bifida, patient/ family training in specific areas, such as bladder and bowel management, skin and wound care, genetic counseling, limited psychosocial counseling, and linkage to other clinical and community services. CNS Oncology Team The Brain Tumor Service at RCHSD is one of the largest pediatric care facilities for children with brain tumors in the western United States. It consists of physicians, nurses, social workers, LEFT TO RIGHT: Hal Meltzer, Melissa Griffin, Michael Levy, Ashley Wagner Neurosurgery neurosurgery v4.indd 23 23 1/27/14 10:49 AM child life specialists, parent liaisons and chaplains who help each family through the initial surgery and subsequent radiation and/or chemotherapy regimens. Services involved include Hematology/ Oncology, Neurosurgery, Neurology, Radiology, Pathology, Ophthalmology, Craniofacial, Head and Neck Surgery, and Rehabilitation. Children are treated with state-of-the-art medical and surgical programs. The center specializes in the treatment of complex tumors in children involving the midline, posterior fossa, Cerebellopontine angle, and skull base. John R. Crawford, MD directs the neuro-oncology program. He is the co-director of the multidisciplinary neuro-oncology clinic and leads the Monthly CNS Tumor Conferences. He has also developed close relationships on an international level allowing for the inpatient surgery and care for children with complex brain tumor from both Hospital Infantil de las Californias in Tijuana and throughout the world. Complex radiation therapies are provided by Kevin Murphy, MD, who serves as the Chief of the Pediatric Radiation Oncology Service, and is an active member of the Children’s Oncology Group (COG,) and Hal S. Meltzer, MD. Dr. Murphy also serves as a regional resource and primary radiation oncologist for RCHSD. Dr. Murphy has used and fostered the development of a number of emerging techniques in the treatment of brain tumors in children including Stereotactic Radiosurgery (SRS), Stereotactic Radiotherapy (SRT), Intensity Modulated Stereotactic Radiosurgery/Therapy (IMRS/ IMRT), Hypo-fractionated Stereotactic Radiotherapy and Gliasite Iotrex brachytherapy. Dr. Meltzer continues to direct and develop the Gamma Knife and Proton Beam Stereotactic Programs. The Division has developed a tissue bank at RCHSD (IRB 091542) and has developed close relationships with laboratories at the Scripps Institute, UCSD, and Burnham Institute over the past years. Brachial Plexus Team Justin M. Brown, MD continued to direct a multidisciplinary team for 24 children with brachial plexus palsy, facial nerve injury, and peripheral nerve injury consisting of orthopedics, neurosurgery, occupational therapy/hand therapy, and physician assistants and nurse clinic coordinators. He bring manys years of expertise dealing with the complex issues that can arise, and has evaluated hundreds of children with brachial plexus injuries. The team provides comprehensive evaluations and follow-up services as needed. Brachial plexus and other peripheral nerve surgeries currently represent a strength at RCHSD that we continue to address in conjunction with the UCSD Department of Neurosurgery. Neurosurgery and Pediatric Dysmorphology Craniofacial Services and Plastic Surgical Services and the Neurocraniofacial Team at RCHSD are among the most respected centers in the United States. The Division’s surgeons and physicians have achieved international reputations in craniofacial surgery, genetics and dysmorphology, neurological surgery, bone biology and basic bone research, and information technology. Presently, the Division offers tertiary care services for some of the county’s most complex cases, including major skull base surgery, endoscopic cranial reconstruction, distraction osteogenesis for midface and mandibular advancement, apnea and airway problems in newborns and children, orbital tumors, facial nerve paralysis, microsurgery and pediatric burn care. From 2011 to 2012, we performed 90 Craniofacial Procedures (80% Open and 20% Endoscopic). The Neurosurgical and Craniofacial Services are seeing clinic patients primarily in the Fresh Start Children’s Hospital Clinic and involved directly with the patient populations brought to RCHSD from other countries for charitable surgical interventions. Neurovascular A specific Vascular Clinic Program is held at RCHSD with participation from institutions throughout the San Diego area including UCSD, Sharp, San Diego Naval Medical Center and Kaiser Permanente Medical Center. The clinic is dedicated to a multidisciplinary approach toward the management of children and adults with complex or deforming vascular lesions. Dr. Lawrence F. Eichenfield is director of the vascular lesion clinic and is an internationally recognized expert in the area of pediatric and adolescent dermatology. The multidisciplinary team includes renowned specialists in plastic and craniofacial surgery, dermatology, diagnostic imaging and interventional radiology, laser surgery, genetics, orthopedics, otolaryngology and ophthalmology. The Division initiated a novel Cerebrovascular Multidisciplinary Clinic in 2009 including Neurosurgery, Neurology, Radiation Oncology, and Neuro-interventional Radiology. We now perform Pediatric Neuro-Interventional procedures at RCHSD with the addition of Alexander A. Khalessi, MD, MS. He performs both diagnostic and therapeutic interventions for cerebral vascular malformations and tumors in children. Membership in Professional Societies Participation in professional societies has occurred at the regional, national, and international levels with a diffuse focus on numerous aspects of medicine. At the local level, Dr. Levy has been involved with the Los Angeles County Medical Association, Salerni Collegium-University of Southern California School of Medicine, California House Officer Medical Society, and Los Angeles Academy of Medicine. At the regional level, Dr. Levy has been involved with the California Medical Association, California Neurosurgical Association for Pediatrics, the American College of Surgeons in Los Angeles and San Diego, the Western Neurosurgical Society, and the San Diego Medical Society. At the national level, Dr. Levy has been involved with Alpha Omega Alpha, the American Association of Neurological Surgeons, the American Medical Association, the Congress of Neurological Surgeons, the Joint Section of Cerebrovascular Neurosurgery, the Joint Section of Pediatric Neurosurgery, the American Society of Pediatric Neurosurgery neurosurgery v4.indd 24 1/23/14 4:42 PM Neurosurgery, the American College of Surgeons, and the American Academy of Neurological Surgery. At the international level, Dr. Levy has been involved with the Society of University Neurosurgeons and the Italian Congress of Neurosurgery. Dr. Levy is a member of the Physicians Advisory Committee on Healthcare (2009–Current) and an Honorary Chairman for the State of California by the National Republican Congressional Committee (Chairman Pete Sessions. He was a member of the Member Benefit Development Committee (2007–2011) for the AANS, a member of the Executive (2005–Current) and Future Meetings (2006–Current) Committees for the Society of University Neurosurgeons and President Elect for 2015. Additionally, he is a Surgical Consultant for the NFL and NFL Players Association (NFLPA) (2010–Current). Reviewing Grants and Manuscripts With regard to peer-review, Michael Levy is a member of the Editorial Advisory Board for the journal Neurosurgery (elected in 2009), the Journal of Health Communications (1995–Current), and World Neurosurgery (2009–current). Michael Levy is currently an Ad hoc reviewer for the Journal of Biomechanical Engineering, M Sacks (ed.) (2008–Current), the Journal of Expert Review of Dermatology (2007–Current), the Journal of Neuropsychiatry and Clinical Neurosciences, S Yudofsky (ed.) 2007–Current, and the Journal of Clinical Neurology and Neurosurgery, E De Deyn (ed.) (2007– Current). Michael Levy has additionally served as a reviewer for AAAS Grant Reviews (2010–Current) and previously for the Wireless Augmented Reality Prototype (WARP) In-Progress Review for NASA Headquarters, Life Sciences Division (NASA Code UL). Michael Levy is currently on the Medical Advisory Boards for the National Hydrocephalus Association (1998 –Current), Arachnoid Cyst Foundation (2004–Current), Board of Directors for the Autism Tree Project Foundation (2002–Current), the Medical Board of Directors for Stemedica Inc. neurosurgery v4.indd 25 (2007–Current), and an Executive Member of the Medical Board of Directors for the Holy Innocents Hospital, Mbarara, Uganda (2010–Current). Michael Levy is additionally a member for the Board of Directors for the charitable organizations INCA and OMNI. TEACHING The Division was certified by the American Board of Pediatric Neurological Surgery to have a Board Certified Fellowship in pediatric neurosurgery with inclusion in the Match beginning in 2009. Our current fellow, Alexa Reeves, MD started the program in 2013. We also continue to train International Fellows throughout the world. Our first Fellow in pediatric neurosurgery graduated in 2010 and is currently working at the Barrow Institute in Phoenix, Arizona. Only 22 such Fellowships exist in the US and only 40% of those match a Fellow each year. We review and participate in the clinical in-service education programs and assure the delivery of quality pediatric clinical services, as appropriate and feasible. This results in our providing bi-monthly conferences to the ICU Fellows, semi-annual trauma conferences, and bi-annual lectures to the ancillary and nursing personnel in the IMU and ICU, lectures to the Residents in pediatrics, and frequent presentations at Grand Rounds and Morbidity and Mortality Conference. We also participate in undergraduate, graduate and post-graduate education programs. We have been responsible for educational conferences including Pediatrics, the Trauma Division, and the Pediatric ICU Team. Michael Levy continues our yearly International Outreach Program with visits to pediatric facilities in Managua, Nicaragua, Lima, Peru, Kiev, Ukraine, and Mbarara, Uganda, in the past years. Over the past two years, Michael Levy has worked as an Executive Board Member (and current Medical Director) on the development, and construction, and current medical management of Holy Innocents Children’s Hospital in Mbarara, Uganda. He travels there every January to assess medical care and institutional needs. • • • • MAJOR GOALS & PLANS Continue to develop what will be regarding as one of the largest centers for the care of children with tumors of the brain and spinal cord in the United States. Develop personalized therapies for the management of children with malignant brain tumors which will direct targeted therapies developed based upon analysis of the tumor type. Complete the integration of CT imaging, endoscopy, Pathology Telemedicine, and three-dimensional imagingthe in the Liam’s Neurosurgical Operative Suite. Promote and further develop our clinical relationships in Africa, Eastern Europe, South, and Central America. 1/27/14 9:56 AM We have assisted in developing an Educational Skull Base Dissection Laboratory for resident education in surgical anatomy and approaches. We have helped to develop a 3D video display system which maximizes the information available to residents and medical students during surgery. We have had significant involvement in the education of pre-medical students, medical students, residents, and fellows over the past 15 years. At the national and international level, Michael Levy has been involved in the creation of numerous educational opportunities including being a member of the CNS Publications Committee (Current), and AANS Member Benefit Development Committee (Current) which is a program that facilitates member education. For the Society of University Neurosurgeons, he was Program Director of the Annual Meeting in San Diego (2006), on the Executive Committee (2006–Current), and President Elect in 2015. He currently serves as a mentor for pre-medical students clinical rotations (2003–Present) and as a mentor for UCSD pre-medical student and resident international charity programs including INCA, OMNI, Fresh Start, and UCSD Project Nicaragua (2003–Present). He was awarded the UCSD Division of Neurosurgery Resident Teaching Award in 2007. AWARDS,HONORSAND PRESENTATIONS Divisional Publications Peer Reviewed: Hayden MG, Hughes S, Hahn EJ, Aryan HE, Levy ML, Jandial R. Maria Auxiliadora Hospital in Lima, Peru as a model for neurosurgical outreach to international charity hospitals. Childs Nerv Syst, 27:145-148, 2011. Jandial R, Levy ML. Cellular Alchemy: Induced Pluripotent Stem Cells Retain Epigenetic Memory. World Neurosurgery, 75:5-6, 2011. Newman CB, Park MS, Kerber CW, Levy ML, Barr JD, Pakbaz RS. Over-the-catheter retrieval of a retained microcatheter following Onyx embolization: a technical report. J Neurointerv Surg, 10:1136, 2011. 26 Baird LC, Gonda D, Cohen SR, Evers LH, Lefloch N, Meltzer HS, Levy ML. Craniofacial reconstruction as a treatment for elevated intracranial pressure. Childs Nerv Syst, 28:411-418, 2012. Jandial R, Anderson A, Choy C, Levy ML. Bidirectional microevnironmental cues between neoplastic and stromal cells drive metastasis formation and efficiency. Neurosurgery, 70N12-13, 2012. Levy ML, Kasasbeh AS, Baird LC, Amene C, Skeen J, Marshall L. Concussions in Soccer: A Current Understanding. World Neurosurg 78(5):535-44, 2012 Smith RD, Reeves A, Azeez A, Levy ML. Human Oocytes Reprogram Somatic Cells to a Pluripotent State. World Neurosurg, 77:9-11, 2012. Huang M, Nichols S, Robb A, Angeles A, Drake A, Holland M, Asmussen S, D’Andrea J, Chun W, Levy ML, Cui L, Song T, Baker DG, Hammer P, McLay R, Theilmann RJ, Coimbra R, Diwakar M, Boyd C, Neff J, Liu TT, Webb-Murphy J, Farinpour R, Cheung C, Harrington DL, Heister D, Lee RR. An Automatic MEG Low-Frequency Source Imaging Approach for Detecting Injuries in Mild and Moderate TBI Patients with Blast and Non-Blast Causes: NeuroImage, 61:1067-1082, 2012. Harbert MJ, Yeh-Nayre L, O’Halloran H, Levy ML, Crawford J. Unrecognized visual field deficits in children with primary central nervous system brain tumors. Journal of Neuro-Oncology 107(3):545-549 2012. Duenas VJ, Hahn EJ, Aryan HE, Levy ML, Jandial R. Targeted neurosurgical outreach: 5-year follow-up of operative skill transfer and sustainable care in Lima, Peru. Childs Nerv Syst, 28:1227–1231 2012. Levy ML, Duenas VJ, Hambrecht AC, Hahn EJ, Aryan HE, Jandial R. Pediatric Neurosurgery Outreach: Sustainability Appraisal of a Targeted Teaching Model in Kiev, Ukraine. Journal of Surgical Education, 69(5):612–616 2012. Wong RK, Emelin JK, Meltzer HS, Levy ML, Cohen SR. Nonsyndromic Craniosynostosis: The Rady Children’s Hospital Approach. J Craniofac Surg, 23(7 Suppl 1):S119-123 2012. Northcott PA, DJH Shih, Peacock J, Garzia L, Morrissy S, StГјtz AM, Zichner T, Korshunov A, et. al Levy ML. Subgroup specific somatic copy number aberrations in the medulloblastoma genome. Nature, 488:49–56, 2012. Udaka YT, Lanipua AY, Amene CS, VandenBerg SR, Levy ML, Crawford JR. Recurrent Pediatric Central Nervous System Low-Grade Gliomas: The Role of Surveillance Neuroimaging in Asymptomatic Children. J Neurosurg Pediatr, 11(2):119-126, 2012. Kharazi A, Lin CM, Visperas MC, Levy ML. Chicken Embryonic Brain: An In Vivo Model for Verifying Neural Stem Cell Potency. JNS, 118:1-8, 2013. Hambrecht A, Duenas MJ, Hahn EJ, Aryan HE, Hughes SA, Waters D, Levy ML, Jandial R. Strategic design for pediatric neurosurgery missions across the Western Hemisphere. Surgical Neurology International, 4:62:1-3 2013. Gold J, Levy ML, Crawford J. Giant Plexiform Neurofibroma Causing Asymptomatic Cervical Spinal Cord Compression in a Child with Neurofibromatosis Type 1. BMJ, 1–3 2013. Keshavarzi S, MacDougall M, Lulic D, Kasasbeh A, Levy ML. Experience with the SURGICELВ® Family of Absorbable Hemostats (Oxidized Regenerated Cellulose) in Neurosurgical Applications: A Review WOUNDS W-12-00086 2013. Markant SL, Esparza LA, Sun J, Barton KL, McCoig LM, Grant GA, Crawford JR, Levy ML, Northcott PA, Shih D, Remke M, Taylor MD, Wechsler-Reya1 RJ. Targeting Sonic Hedgehog-Associated Medulloblastoma Through Inhibition of Aurora and Polo-Like Kinases. Cancer, 12-4258R-A, 2013. Crawford J, Shayan K, Levy, M. Delayed Presentation of Diencephalic Syndrome Associated with Leptomeningeal Dissemination in a Child. BMJ Case Reports, doi:10.1136, 2013. Crawford J, Newbury R, Levy ML. An Unusual Posterior Fossa Tumour in a Young Child. BMJ Case Reports, doi:10.1136, 2013. Gonda DD, Meltzer HS, Crawford JR, Hilfiker ML, Shellington DK, Peter- Neurosurgery neurosurgery v4.indd 26 1/23/14 4:43 PM son BM, Levy ML. Complications associated with prolonged hypertonic saline therapy in children with elevated intracranial pressure. Pediatr Crit Care Med, 14(6):610-620, 2013. Ceponiene R, Levy ML, Crawford J: Lobar haemorrhagic mass in a young girl with neurofibromatosis type 1. BMJ Case Reports, doi:10.1136, 2013. Jankowski P, Levy ML, Crawford J: Post Traumatic Basal Ganglia Haemorrhage in Child with Primary Central Nervous System Lymphoma. BMJ Case Reports, doi:10.1136, 2013. Markant SL, Esparza LA, Sun J, Barton KL, McCoig LM, Grant GA, Crawford JR, Levy ML, Northcott PA, Shih D, Remke M, Taylor MD, Wechsler Reya RJ. Targeting Sonic Hedgehog-associated medulloblastoma through inhibition of Aurora and Polo-Like Kinases. Cancer Res, 2013 (in press). Udaka T, Shayan K, Yeh-Nayre L, Levy ML, Chuang N Atypical Presentation of Atypical Teratoid Rhabdoid Tumor in a Child Case. Rep Oncol Med, 2013 (in press). Gold JJ, Dory CE, Levy ML, Crawford JR Simultaneous Moyamoya Disease and Cervical Spinal Cord Low Grade Astrocytoma in a Child with Neurofibromatosis Type 1. BMJ Case Rep, 2013 (in press). Crawford J, O’Halloran H, Levy ML: New Presentation of Diabetic Embryopathy in an Infant with Femoral Facial Syndrome, Holoprosencephaly, and Resulting Hydrocephalus. Pediatrics, 2013 (In review). Breithaupt A, Cohen SR, Meltzer H, Broder K, Levy M. Endoscopic repair of craniosynostosis: The role of minimally invasive techniques in the treatment of single suture craniosynostosis (in press). Hambrecht A, Jandial R, Levy ML. Strategic Design for Targeted Pediatric Neurosurgery Teaching Missions across the Western Hemisphere (GHP-12-0071). Global Health Promotion, 2013 (in press). Huang M, Huang C, Robb A, Angeles A, Nichols S, Baker D, Song T, Harrington DL, Theilmann RJ, Srinivasan R, Heister D, Diwakar M, Canive JM, Edgar C, Chen YH, Zhengwei J, Shen M, El-Gabalawy F, Levy ML, McLay R, Webb-Murphy J, Liu TT, Drake A, Lee RR. MEG Source Imaging using Fast L1 Minimum-norm and its Application to Human Resting-state Signals. NeuroImage, 2013 (in press). Abstract/Poster Presentations Peer Reviewed: Levy ML, Baird L. Combined Approaches for the Treatment of Craniopharyngioma. Presented at the Annual American Society for Pediatric Neurosurgery, Lanai, Hawaii, 2011 Crawford JR. Predicting Recurrence in Pediatric Central Nervous System (CNS) Low Grade Gliomas: The Role of MRI Surveillance in Asymptomatic Children. Presented at the Annual American Association of Neurology Meeting, Honolulu, Lanai, Hawaii, 2011 Levy ML, Baird L, Toney J. Punch Drunk. Repetitive injury in boxing. Joe Louis. Presented at the Annual Society for University Neurosurgeons meeting, Athens Greece and Istanbul Turkey, 2011 Levy ML Concussion in young athletes. Presented at the Annual RCHSD When Youth Sports Get Dangerous Symposium, San Diego, CA, 2011 Levy ML, Baird L. Complex Combined Approaches for the Treatment of Craniopharyngioma in Children. Presented at the Annual American Academy of Neurological Surgery, Scottsdale, AZ, 2011 Gonda D, Meltzer HS, Levy ML. Hematologic Abnormalities Observed in Pediatric Patients Treated with Prolonged Continuous Hypertonic Saline for Elevated Intracranial Pressure. Presented at the 61st Annual CNS Meeting, Washington D.C., 2011 Gonda D, Meltzer HS, Levy ML. Incidence of Renal Injury and Failure Measured by the RIFLE Scale in Pediatric Patients Treated with Prolonged Continuous Hypertonic Saline for Elevated Intracranial Pressure. Presented at the 61st Annual CNS Meeting, Washington DC, 2011 Menon J, Meltzer HS, Levy ML. The use of flexible CO2 laser for albumin solder-assisted dural tissue welding. Presented at the 39th Annual ISPN Meeting, Goa, India, 2011 Newman CB, Levy ML. Fatalities in Boxing and Proposal for Future Studies in Combative Sports. Presented at the 12th Annual University of California Neurotrauma Symposium, Santa Barbara, CA, 2011 Kim T, Gonda D, Meltzer HS, Levy ML. Importance of Neurologic Exam in Determining Management of Posterior Fossa Epidural Hematomas. Presented at the 40th Annual Meeting of the AANS/CNS Section on Pediatric Neurological Surgery, Austin, TX, 2011 Levy ML. Surgical intervention for hydrocephalus in Uganda. Presented at the 4th Annual Meeting of the ASAP Building Sustainable Surgical Systems Conference. San Diego, CA, 2011 Freestone L, Levy ML. Building a Children’s Hospital in Southern Uganda, From Conception to Patient Care. Presented at the 4th Annual Meeting of the ASAP Building Sustainable Surgical Systems Conference. San Diego, CA, 2011 Jandial R, Levy ML. INCA: Five-Year Follow-up of neurosurgical Missions to South and Central America. Presented at the 4th Annual Meeting of the ASAP Building Sustainable Surgical Systems Conference. San Diego, CA, 2011 Amene CS, Levy ML. Combined Approaches in the Treatment of Craniopharyngioma. Presented at the 22nd NASBS 2012 Annual Meeting. New Orleans, LA, 2012 Levy ML. Management of Pediatric Intracranial Gunshot Wounds: Predictors of Favorable Outcome and a Proposed Treatment Paradigm: Discussion. Presented at the 2012 Annual AANS Meeting, Miami, FL, 2012. Yeh-Hauer L, Crawford J, Levy ML, Lefloch N, Fagan M. Optimizing Care of the Brain Tumor Patient Through the Development of a Neuro-Oncology Primary Nursing Team. Presented at the 36th Annual Meeting, Pittsburgh, PA, 2012 Levy ML. Learning from failure: Professional and personal resilience. Neurosurgery neurosurgery v4.indd 27 27 1/23/14 4:43 PM Research Support 28 Grant/Contract # Total Direct Dollars Duration of Grant Developmentofneuropathologycoretelemetryfortheintra-operativereview of tissue harvested from children and adolescents with brain tumors BioImagene $280,000.00 2010-Current PhaseI/II,multi-center,open-labelstudytoassessthesafety,tolerability,and preliminary efficacy of a single intravenous dose of allogeneic mesenchymal bone marrow cells to subjects with ischemic stroke IRB#100325R/Stemedica(IND14328) $812,736.00 2011-Current AnexploratoryPhase2studyevaluatingtheefficacyandsafetyoffibrinsealant. Vaporheated,solvent/detergenttreated(FSVSS/D)500S-APRforthesealing of dura defect sutures in posterior fossa surgery IRB# 12121/Baxter $73,730.18 2010-2011 DiagnosingmildTBIinadolescentsandadultsusingMEGandDTI. NFL $99,741.00 2012-Current Using Discarded CSF and Tissue to establish a neurosurgical tissue bank RCHSDIRB#091542 Unfunded 2011-Current Neurosurgical Database at RCHSD for prospective and Retrospective review of neurosurgical cases RCHSD IRB# 12120 Unfunded 2011-Current PerformingAffymetrixSNP6.0arrayson>1200ofMAGICbankmedulloblastomasand using nanostring to subgroup medulloblastomas. RCHSDIRB#091542/UniversityofToronto Unfunded 2011-Current An Integrated MEG and DTI Study for Differential Diagnosis of Mild TBI and PTSD. Huang(PI),Levy(Co-I) 1R01NS072601-01 Funded 2012-Current Diagnosing Mild TBI in VA and Active Duty Military Patients using MEG and DTI. Huang(PI)Levy,(Co-I) 1R01CX000499-01 Funded 2012-Current Humanlysophosphatidicacid(LPAlevels)andgeneticmutationsinCNSbirthdefects.; Yung(PI)ScrippsResearchInstitute,Levy(PI) RCHSDIRB#091542 Funded 2011-Current Developing an in vivo model for verifying neural stem cell potency in chicken embryonic brain.Levy(Co-PI) Stemedica/Department of Research and Development Funded 2012-Current UtilizationofintraoperativeCTangiographyandcomparisontostandardangiographyin childrenwithvascularmalformations.Levy(PI) RCHSD IRB# 12120/Ceretom Technologies Funded 2011-Current Targeting Sonic Hedgehog-associated medulloblastoma through inhibition of Aurora and Polo-Like Kinases RCHSDIRB#091542 Funded 2012-Current Neurosurgery neurosurgery v4.indd 28 1/23/14 4:43 PM Presented at the Senior Society of Neurosurgeons resident Boot-Camp Annual Meeting, San Diego, CA 2013 RCHSD, Brain Trauma Research Focus Group RCHSD, Liam’s Fund Charity Books Edited: Berta S, Nader R, Levy ML (eds). Neurosurgery Tricks of the Trade Volumes 1 and 2, Thieme, New York 2013. Establishment of New Teaching Venues The Division has developed Educational Skull Base Dissection Laboratories for Resident Education in surgical anatomy and approaches. We have worked with Johnson and Johnson Medical to develop educational materials regarding the use of hemostatic agents during neurosurgical procedures. RESEARCH AND FUNDING Revolutionary surgical techniques and technologically advanced approaches remain a primary pursuit of the Neurosurgical Team. New technology in neurosurgery includes the continued development of novel Robotic and three-dimensional endoscopes, High Definition 3D monitors for intra-operative use, and the potential uses of intra-operative CT imaging in 2013. We continue to work with our partner companies to advance closer to the reality of true stereoscopic endoscopes (Hans Hoag, PhD–Endactive technologies; Wei Su, PhD-IntraVista Medical Systems Inc., and Kaiser Medical). We have assisted in the development of a 3D displays which is utilized in our operative setting as a front projection 3D image. The primary purpose is for education and allowing the nursing and anesthesia teams to be consistently aware of the course of the surgical intervention. Current avenues of research also include the evaluation of cGMP in novel neuronal stem cell lines, MEG imaging and neuropsychiatric testing for mild closed head trauma in adolescents, and the potential benefits of Neuronal and Mesenchymal based stem cells for treatment of stroke. UNIVERSITY AND PUBLIC SERVICE MichaelL.Levy,MD,PhD RCHSD, Advertising and Public Relations Committee RCHSD, Innovation and Technology Committee RCHSD, HIPAC RCHSD, U.S. News & World Report Subcommittee RCHSD, Academic Council Philanthropy Team neurosurgery v4.indd 29 PATENTS AND INVENTIONS Pluronic Surfactant Based Bone Wax (CHLA #99-09 Bonewax) which allows for the use of bone wax in all scenarios without risk of infection or non-union EndActive Robotic Omnidirectional Neuroendscope (Hans Hoag–California Institute of Technology–Inventor). Development and Construction of the HICH Children’s Hospital in Mbarara, Uganda. Project Nicaragua, INCA and Open Mind Neurosurgical International (OMNI), which are nonprofit organizations providing charitable medical services in the form of neurosurgical procedures and the provision of complex neurosurgical equipment to the underserved and needy around the world. In combination with the Variety Children’s Lifeline, neurosurgeons from RCHSD have traveled to five countries over the past two years. In addition to the surgeries performed in San Diego in 2010, members of the Neurosurgery Division performed surgeries in Lima, Peru, Managua, Nicaragua, and Kiev, Ukraine through these Pediatric Neurosurgical Outreach Programs. PUBLIC SERVICE AND OUTREACH PROGRAMS The Autism Tree Project Foundation which was founded in 2003 to promote autism education and provide early intervention programs in the California community. Our main programs are a Preschool Screening Program, A quarterly Mentor program that pairs families new to the autism diagnosis with a “Mentor” to support and guide the family as well as assist in identifying autism related resources in the community, and a Preschool Teacher Training Program. Liam’s Fund, which assists in procuring sophisticated equipment for use in the neurosurgical operating room in hopes of reducing the number of surgeries performed and significantly increasing the number of successful procedures for children requiring neurosurgical interventions. Over the past year Liam’s Fund has assisted in the funding of the Neurosurgical Operating room at RCHSD, now called the Liam’s Fund Neurosurgical Suite. Holy Innocents Children’s Hospital Board of Directors. assisted with the 1/23/14 4:43 PM Ophthalmology The Division of Ophthalmology has seven physicians, each of whom is board certified by The American Academy of Ophthalmology (AAO) and is a Member of the American Association for Pediatric Ophthalmology and Strabismus (AAPOS). The Division is one of the largest pediatric ophthalmology groups in the United States. Ophthalmology v6.indd 30 1/23/14 4:44 PM FACULTY Preeti Bansal, MD, Acting Director Colin A. Scher, MD Yvette M. Jockin, MD Henry O’Halloran, MD Angela M. Moll, MD Edward W. Brown, MD Chantal Boisvert, MD Sandra Kohler, C.O., C.O.M.T. Mona Adams, OD Dr. Preeti Bansal is board certified in Ophthalmology. She earned her medical degree from the University of Kentucky and completed her residency at the same institution where she was awarded the Tschafter Resident Teaching Award and served as chief resident. She completed a fellowship in Pediatric Ophthalmology and Strabismus at Duke University. She has been with RCSSD since 2005. She is currently the acting director of the Division. She also developed and runs Retinopathy of Prematurity screening and treatment program. Her special interests include Retinopathy of Prematurity and Pediatric Cataracts. Dr. Colin Scher has practiced pediatric ophthalmology at Rady Children’s Hospital-San Diego (RCHSD) for over 20 years. He earned his medical degree from the University of Cape Town in South Africa. While completing his ophthalmology residency at the University of Pennsylvania, he was honored as the senior resident who most exemplified the ideal university resident. Dr. Scher has received awards from the American Academy of Pediatrics and San Diego City schools for outstanding care for underprivileged and uninsured children. In addition to treating pediatric patients, Dr. Scher is a specialist in adult strabismus. Dr. Yvette Jockin specializes in pediatric ophthalmology. She has practiced at RCHSD since 1997. A summa cum laude graduate, she earned her medical degree from the State University of New York at Buffalo, School of Medicine & Biomedical Sciences where she was named class valedictorian. She completed a residency in ophthalmology at Case Western Reserve University Hospitals in Cleveland. Her postgraduate training also included a fellowship in pediatric ophthalmology at Children’s Hospital of Philadelphia. While attending medical school, she was elected to the Alpha Omega Alpha Medical Honor Society and received the Dr. Janet M. Glasgow Award and the Dr. Thomas J. Guttuso Ophthalmology Award. LEFT TO RIGHT: Henry O’Halloran, Jane Kelly, Chantel Boisvert, Edward Brown Ophthalmology Ophthalmology v6.indd 31 31 1/27/14 10:51 AM Dr. Henry O’Halloran is European and American board certified in ophthalmology. He joined Rady Children’s Specialists of San Diego (RCSSD) Division of Ophthalmology in November 2000. He earned his medical degree from Trinity College Medical School in Dublin, Ireland. His postgraduate training included a residency in ophthalmology in Ireland and at the University of Kentucky in Lexington, where he served as chief resident. Dr. O’Halloran also completed a fellowship in neuro-ophthalmology at the University of Kentucky, where he was also an assistant professor. Dr. O’Halloran’s clinical interests are in neuro-ophthalmology, specifically in optic nerve disorders and the management of head injury patients. He is an active volunteer with the Mercy Outreach Surgical Team and has acted as director and treasurer of the team. He is a director of the Scripps Mercy Foundation and a board member of the American Ireland Fund. in Montreal Canada. She completed her Ophthalmology residency at the University of Montreal School of Medicine where she also served as Chief Resident. Dr. Chantal is fellowship trained in Pediatric Ophthalmology as well as Neuro-Ophthalmology. Dr. Angela Moll is a graduate of Wayne Dr. Mona Adams is a licensed Optom- State University School of Medicine and completed a residency at the Kresge Eye Institute at Wayne State where she won the Barsky Research Award. She served as fellow in pediatric ophthalmology and strabismus at Children’s Hospital of Michigan. She has been with RCSSD since 2008. Dr. Edward Brown has 28 years of experience in pediatric ophthalmology providing routine and specialized eye care for infants, children, and adolescents. He graduated from Temple University Medical School and spent his residency in ophthalmology at the Oakland Naval Hospital and the University of California, San Francisco. He finished his training in pediatric ophthalmology after completing a fellowship at the Children’s Hospital of Los Angeles in affilliation with USC. He recently joined RCSSD’s ophthalmology team after 25 years of private practice here in San Diego. Dr. Chantal Boisvert is the newest member of the Division having joined in July 2013. She attained both a Medical Doctorate as well as a Doctorate of Optometry 32 Sandy Kohler, CO has over 20 years of experience in pediatric ophthalmology in the U.S. and on numerous mission trips to Mexico and Honduras. She received her training at a consortium program involving Eastern Virginia Medical School and Old Dominion University. As an Orthoptist, Sandy is uniquely skilled in the evaluation and treatment of children and adults with eye movement difficulties. Her specialty is strabismus, amblyopia and double vision for both adults and children. Sandy has been with Rady’s for over 13 years and is an active volunteer on mission trips with Mercy Outreach Surgical Team. etrist who joined the group in 2012. She completed her training at the Southern California School of Optometry in Fullerton, California where she received several scholarships and was the 1st place recipient at Southern California College of Optometry Student Research Symposium. Dr. Adams specializes in contact lens fitting and training for children and teens. CLINICAL ACTIVITIES INPATIENT/OUTPATIENT All aspects of pediatric ophthalmology are covered by the physicians. Subspecialty interests include oculoplastics, neuro-ophthalmology, lens implants in children, pediatric glaucoma and adult strabismus. The Division also offers eyeglasses for all ages starting at birth, as well as contact lens training and fitting, with special expertise in aphakic babies. A full time orthoptist is a member of the group and provides management of the non-surgical aspects of strabismus, as well as amblyopia and refraction. She is also responsible for keeping technical support up-to-date with the latest techniques and equipment to maximize patient care. RCSSD Ophthalmology is based on the RCHSD campus. The satellite clinics that are served include Encinitas, Escondido, and Murrieta. The Division is especially proud of our devotion to premature babies. We are the only group of ophthalmologists servicing thirteen neonatal units ranging from Chula Vista in the South, Oceanside in the North and Rancho Springs in Riverside County. The Division is also the only ophthalmology group that covers RCHSD for inpatient consultations, emergency room consultations, urgent care and trauma call. All pediatric ophthalmology surgery provided by the group is done at RCHSD. RESEARCH ACTIVITIES The Ophthalmology Division focuses its research efforts on Pediatric Intraocular Lens implantation, pediatric refractive surgery, pediatric glaucoma and eye trauma. Recent Clinical Trials: • Clinical Study C-10-004 Durezol Pediatric Cataract Study • ClinicalEvaluationofMyopiaControl Spectacles • A multicenter Double-masked Randomized, Active Controlled Parallel Study of the Safety and Efficacy of Once daily Bimatoprost Preservative free Ophthalmic Solution in Pediatric Patients with Glaucoma TEACHING ACTIVITIES The Division of Ophthalmology offers clinical training for medical students, pediatric and family practice residents and pediatric specialty fellows. The Division is actively involved in clinical research and provides opportunities for trainees to contribute to the fields of Ophthalmology and Pediatrics. PUBLICATIONS O’Halloran HS. HIV-Neuroophthalmology. In: Continuum of Neurology, J.R. Berger (ed), American Academy of Neurology, in press. Ophthalmology Ophthalmology v6.indd 32 1/23/14 4:44 PM MAJOR GOALS & PLANS • • • • • • • Ophthalmology v6.indd 33 Cement amalgamation with UCSD Department of Ophthalmology Develop a clinical research program when the joint Rady Children’s Hospital-UCSD Ph.D. comes to fruition Increase clinical presence in Murrieta and Encinitas Rapid response to in-house consultations Develop appropriately reimbursed contractual arrangements with regional and local NICUs Clinic and OR teaching of ophthalmology residents Increased teaching of residents in the hospital setting 1/27/14 10:05 AM Orthopedics & Scoliosis The Pediatric Orthopedic and Scoliosis Division addresses the unique musculoskeletal needs of growing children and adolescents. Childhood injuries or disease may alter or impede growth; Rady Children’s Specialists of Diego (RCSSD) orthopedists work to ensure optimal lifetime function for every child. In 2011, the Pediatric Orthopedic and Scoliosis Division was ranked 4th in the nation by the U.S. News & World Report. ortho surg v5.indd 34 1/27/14 10:34 AM FACULTY Scott J. Mubarak, MD, Professor of Clinical Orthopedic Surgery, Department of Orthopedic Surgery, UCSD; Vice Chief of Division of Orthopedic Surgery, Rady Children’s Hospital Medical Practice Foundation Dennis Wenger, MD, Voluntary Clinical Professor of Orthopedic Surgery, UCSD; Director of Orthopedic Training Program, RCHSD Henry Chambers, MD, Professor of Clinical Orthopedic Surgery, UCSD; Director of Motion Analysis Laboratory, RCHSD; Director of Southern California Cerebral Palsy Center; Co-Director of Pediatric and Adolescent Sports Medicine Peter Newton, MD, Voluntary Clinical Professor of Orthopedic Surgery, UCSD; Chief of Division of Orthopedic Surgery, Rady Children’s Hospital Medical Practice Foundation, Director of Orthopedic Research and the Scoliosis Service, RCHSD C. Douglas Wallace, MD, Associate Clinical Professor of Orthopedic Surgery, UCSD; Director of Orthopedic Trauma, RCHSD Maya Pring, MD, Associate Clinical Professor of Orthopedic Surgery, UCSD Burt Yaszay, MD, Voluntary Assistant Clinical Professor of Orthopedic Surgery, UCSD Eric Edmonds, MD, Assistant Clinical Professor of Orthopedic Surgery, UCSD Co-Director of Pediatric and Adolescent Sports Medicine Andrew T. Pennock, MD, Assistant Clinical Professor of Orthopedic Surgery, UCSD POSTDOCTORAL FELLOWS (2012-2013) Avrum Joffe, MD John Kempainen, MD Brian Scannell, MD Chris Souder, MD (2013-2014) Matt Hollenbeck, MD Jonathan Peterson, MD Lee Phillips, MD Lissette Salgueiro-Canetti, MD LEFT TO RIGHT: Maya Pring, Dennis Wegner, Salil Upasani, Eric Edmonds, Henry Chambers, Doug Wallace, Peter Newton, Burt Yaszay, Scott Mubarak, Andrew Pennock Orthopedics & Scoliosis ortho surg v5.indd 35 35 1/27/14 10:52 AM NURSE PRACTITIONERS/ PHYSICIAN ASSISTANTS Chrissy Paik, PA-C Amanda Asaro, PA-C Linh Darnell, PA-C Allison Dickinson, PA-C Kathryn Fowle, CPNP Lynn Manheim, CPNP Sunny Park, CPNP Kelly Pretorius CPNP Raquel Sanchez, PA-C Mary Lou Scott, CPNP Phil Stearns, CPNP Chris Orr, PAC CLINICAL ACTIVITIES INPATIENT/OUTPATIENT The Division is the only comprehensive orthopedic group in San Diego and Imperial counties with specialists who practice full time pediatric orthopedics. By devoting their entire careers to the care of children, these specialists can provide individualized assessment, early diagnosis, and appropriate treatment for all pediatric and adolescent orthopedic problems, including: fracture care (casting and/or operative fixation); spine abnormalities (scoliosis, kyphosis and spondylolisthesis); foot deformities (Ponseti casting, tarsal coalition, toeing in, clubfoot, flatfeet); hip disorders (hip dysplasia and dislocation, Legg-CalvePerthes disease); sports medicine (knee and shoulder arthroscopy) brachial plexus palsy; and cerebral palsy (gait enhancement). The Division also works with RCHSD to provide advanced biomechanical analysis through the Motion Analysis Laboratory and low dose pediatric imaging services. RESEARCH ACTIVITIES The orthopedic research program at RCHSD is designed to keep the Division at the forefront of advances in orthopedic treatment in order to share best practices and new discoveries within the field. The program has attracted external grants from industry, professional organizations and federal sources, as well as philanthropic funding. In 2012, the department members contributed to 51 scientific presentations at national and international meetings (Annual Meetings of the 36 American Academy of Orthopedic Surgeons, Pediatric Orthopedic Society of North America, Scoliosis Research Society, Orthopedic Research Society, and the International Meeting on Advanced Spinal Techniques). In addition to the Division’s ten attending orthopedic surgeons, orthopedic research at RCHSD is conducted and carried out by many other physicians, research support staff, and trainees. Pediatric orthopedic fellows are actively involved in research during their fellowship training year. International fellows as well as residents from UCSD, the U.S. Navy and U.S. Air Force regularly participate in one or more research projects during their rotations. Each year, the Division hosts a resident from the UCSD orthopedic residency program for training in orthopedic research. The Orthopedic Division also has internal resources for conducting sophisticated statistical analyses, which lends enhanced scientific validity and detailed data analysis to its research studies. The Division employs administrative support for budgeting, contracting and project management. To further its research goals in clinical, biomechanical, and in vivo research methodologies, the Orthopedic Division has established specific synergistic centers of research: • The Center for Spinal Deformities Research • TheCenterforPediatricandAdolescent Sports Medicine Research • TheCenterforHipResearch • The Orthopedic Biomechanics Research Center • The Motion Analysis Laboratory/ Center for Human Performance The Center for Spinal Deformities works with a very active clinical spine service under the supervision of Dr. Peter Newton. With the help of industry grants and participation in the multi-center international spinal deformity Harms Study Group, the center has added three full-time research staff and one research nurse. The center’s research has primarily focused on identifying the optimal treatment for adolescent idiopathic scoliosis (AIS) patients. Currently, all patients undergoing surgical correction of AIS are consented to participate in research and followed for a minimum of five years. The center collects pre-operative and post-operative clinical and radiographic data, and performs pulmonary function tests on each patient. A secure web-based database allows all sites to enter and query de-identified patient data, which includes digital x-rays and clinical photos. This system has proven to be successful in advancing knowledge of scoliosis treatment and help disseminate treatment information at international and national meetings, and in peer reviewed journals. The center has also launched similar prospective research studies for Scheuermann’s kyphosis and scoliosis in patients with Cerebral Palsy, and plans to continue in vivo research and its work with the Orthopedic Biomechanics Research Center. It also serves as a site for a multi-center, NIH funded study investigating the efficacy of bracing in patients with adolescent idiopathic scoliosis. All patients who visit the orthopedic department for clinical evaluation of spinal deformity undergo radiographic examination in the EOSВ® Imaging booth, which allows for a fast, biplanar, lowdose, standing x-ray acquisition. These images are also capable of undergoing 3D reconstruction for research purposes. The Center for Pediatric and Adolescent Sports Medicine Research is our youngest center, established to support the efforts of the surgeons within the 360 Sports Medicine program at RCHSD. The research within this center focuses on specific sports related injuries, as well as general orthopedic trauma treatment – which quite often are a result of sporting activity. Projects within this center have examined the outcome of varying treatment approaches for skeletal injuries and predictors of treatment failures. The surgeons in this center are currently participating in prospective multi-center studies to develop registries for clavicle fractures and treatment of osteochondritis dissecans of the knee. Extensive study into shoulder injuries in children and adolescents is also a major focus and efforts are currently underway to validate a subjective shoulder outcome tool specific to this age group. Efforts to better understand Orthopedics & Scoliosis ortho surg v5.indd 36 1/23/14 4:45 PM MAJOR GOALS & PLANS ortho surg v5.indd 37 The Pediatric Orthopedic Division at RCHSD and UCSD is recognized as one of the best in the world for its clinical care, innovative teaching and advanced research. The Division plans to: • Be the top children’s clinical and research orthopedic center in the United States, drawing patients from throughout the western United States, as well as Europe, Central and South America, and Asia. The quality of the Division’s clinical work and outstanding research will ensure state-of-the-art methods for treating children’s conditions. • Continue its widely recognized fellowship training program in children’s orthopedics while supplementing the international fellowship division to ensure that there are always two or three international fellows conducting research with the North American fellows. • Actively raise funds for additional research and establish at least three funded, named eponymous professorships in children’s orthopedics. • Expand research and clinical assessment of 3-dimensional spinal and limb alignment with new EOS x-ray machine, which allows for up-right weight bearing exams. 1/27/14 10:12 AM Research Support Grant/Contract # Total Direct Dollars Duration of Grant Insall vs. MPFL Reconstructive Surgery for Recurrent Patella Instability (Edmonds) UCSD (sub-award)/OREF $141,865 Jan. 2011-Dec. 2013 St.GilesYoungInvestigatorAward:BarFormationinPhysealFractures:TheUtilityof Interpositional Fat Graft Using Laprine Model Pediatric Orthopedic Society of North America (POSNA) $7,635 July 2010-June 2012 10 year follow ups: Prospective Study of Motion Preservation Evaluation below Fusions of the Spine in Adolescent Idiopathic Scoliosis (Newton) SSSF/SRS $9,586 Apr. 2010-Sept. 2012 Three-Dimensional Analysis of the Deformation and Corrective Forces in the Spinal Rods for Scoliosis Correction (Newton) Pediatric Orthopaedic Society of North America (POSNA) $25,000 Mar. 2010-May 2011 BracinginAdolescentIdiopathicScoliosis(BrAIST)(Newton) University of Iowa (NIH SubAward) $19,278 Sept. 2010-Aug. 2013 BrAISTII:Minimum2-YearFollow-upofBrAISTCohort(Newton) University of Iowa $4,338 Jan. 2013-June 2014 3DVisualizationofVertebralGrowthCartilageandDisc;theEffectsofGrowthModulation $9,987 (Newton) Mar. 2011-Mar. 2012 Scoliosis Research Society (SRS) 38 FOX Pediatric Spinal Deformity Study (Newton) WashingtonUniversity(JohnandMarcellaFoxFundSubaward) [ $ missing ] Oct.2010-Dec.2015 ProspectiveStudyofScheuermann’sKyphosis(Newton/Yaszay) SSSF/DePuy Synthes Spine $18,300 Nov. 2010-Dec. 2013 ScoliosisSurgeryOutcomesDatabaseRegistry:AProspective,Multi-centerDatabase Registry of the Harms Study Group (AIS) (Newton/Yaszay) SSSF/ DePuy Synthes Spine $345,967 Nov. 2010-Dec. 2016 Prospective Study of Cerebral Palsy Scoliosis (Newton/Yaszay) SSSF/ DePuy Synthes Spine $126,840 Nov. 2010-Dec. 2016 ProspectiveStudyofMotionPreservationEvaluationbelowFusionsoftheSpinein Adolescent Idiopathic Scoliosis (Newton/Yaszay) Setting Scoliosis Straight Foundation(SSSF)/ DePuy Synthes Spine $59,875 Apr. 2009-Dec. 2013 InVitro,BiomechanicalAnalysisofUpperFoundationSpineandRibAnchors(Glaser) San Diego Spine Foundation (SDSF) $4,051 Oct. 2010-Oct. 2011 Validation of the EOS 3D Reconstruction Accuracy against CT (Glaser) EOS Imaging $20,839 Jan. 2011-June 2011 Orthopedics & Scoliosis ortho surg v5.indd 38 1/23/14 4:45 PM Research Support Grant/Contract # Total Direct Dollars Duration of Grant Real-TimeAnalysisoftheBiomechanicsandtheEffectivenessofFusionlessSpinal Growth Modulation Devices (Glaser) Scoliosis Research Society (SRS) $25,000 Mar. 2011-Mar. 2013 Foot Drop Device (Glaser) US Navy Medical Center $146,625 Sept. 2012-Sept. 2013 Three Dimensional Analysis of the Growth Plate and Intervertebral Cellular Responses to Spinal Growth Modulation in the fusionless Treatment of Scoliosis: A Pilot Study in an Immature Porcine Model Orthopedic Education and Research Foundation (OREF) $5,000 July 2013-June 2014 sports injuries radiographically have also been undertaken, in collaboration with pediatric radiologists at this institution. The efforts of the Center for Hip Research revolve around the four major diagnoses encountered by pediatric hip surgeons; developmental dysplasia of the hip (DDH), Legg-Calve-Perthes disease (Perthes), slipped capital femoral epiphysis (SCFE), and femoroacetabular impingement (FAI). Research into these four conditions attempts to better understand the evolution of the conditions, stages of disease, and the ideal treatment outcomes. Our department is participating in a multi-center prospective study evaluating the treatment outcomes for patients with DDH, as part of the International Hip Dysplasia Institute (IHDI). A prospective registry to gather extensive data on patients with FAI was recently established and it is anticipated a similar approach to SCFE patients will be undertaken with the next year. This research center has also taken advantage of the opportunity created by the EOSВ® Imaging booth, which allows for standing radiographic image of the pelvis. Recent studies have evaluated pelvic parameters in this natural standing state in scoliosis patients with no hip disease as well as patients with symptomatic hip disease. Future work will explore the capabilities of the system for creating 3D reconstructions of the pelvis and femur. TheOrthopedicBiomechanicsResearch Center(OBRC),foundedin1998andled by Dr. Peter Newton under the direction of Diana Glaser, PhD, applies advanced engineering tools and methods to evaluate techniques and instrumentation used to correct orthopedic problems and deformities. The lab has received several grants to evaluate current spinal devices and a new technique for fusionless scoliosis surgery. These studies, along with research presentations and publications, have made the lab a world-recognized facility in this area of orthopedic research. The lab has also made significant progress toward understanding the biomechanical effects of various surgical techniques for stabilizing adolescent fractures of the humerus, femur and tibia, and in exploring the biomechanical effects of pediatric hip deformity. These cumulative research efforts have been accomplished by pairing orthopedic surgeons and biomedical engineers with orthopedic residents and fellows. Engineering interns and medical students are also recruited to help with each project. This multi-layered approach has yielded significant success with prolific publications appearing in Spine, the Journal of Pediatric Orthopaedics, Clinical Orthopaedics and Related Research, the American Journal of Sports Medicine, the Journal of Shoulder and Elbow Surgery, Medicine and Science in Sports and Exercise, the Journal of Foot and Ankle Surgery, Arthroscopy and the Journal of AppliedBiomechanics. The Motion Analysis Laboratory (MAL) has been utilizing and developing technological resources for the advanced diagnosis and treatment of orthopedic problems since 1974. Led by Dr. Henry Chambers, the internationally recognized MAL specializes in the diagnosis and treatment of orthopedic dysfunction in cerebral palsy. The MAL uses modern computer technology and high-speed digital cameras to obtain detailed reports of how patients move while walking compared to age-related data of normal walkingpatterns.Bystudyingthedifferences, an orthopedic surgeon can develop an individualized treatment plan, with recommendations for orthoses, physical therapy or surgery, if necessary. The Center for Human Performance (CHP) was established by Arnel Aguinaldo, MA in 2001. Utilizing MAL technology, the center’s main objectives are studying and providing feedback on athletic performance and injury prevention in such areas as pitching, golf swing, running, and archery for children, adults and athletes of all ages and levels of competition. The MAL and CHP continue to be at the forefront in the field of human motion study. AWARDS, HONORS AND MAJOR PRESENTATIONS ScottJ.Mubarak,MD • SeniorAchievementAward,AAOS2013 • ElectedtoUCSDAcademyofClinician Scholars 2011 • SteroidInjectionForUnicameralBone Cysts Of The Proximal Humerus In Orthopedics & Scoliosis ortho surg v5.indd 39 39 1/23/14 4:45 PM • • • • 40 The Skeletally Immature. (Bray, Moor, Mubarak). Pediatric Orthopedic Society of North America (POSNA) Annual Meeting, Toronto, CA, May 2013 IPOTT Annual Meeting, Sausalito, CA, October 21, 2011 - Classification and the Need for Intra-Articular Fracture in Children - Septic Arthritis Associated with Closed Intra-Articular Fracture in Children International Pediatric Orthopedic Symposium Annual Meeting, Orlando, FL, December 7-10, 2011 - The Pavlik Harness remains the standard for DDH - Case Discussion: Solving DDH before it Needs an Operation - Practice Management Seminar: ARS Electronic Record, Physician Extenders, Private Practice vs. the Center, When contracts Are Bad, Partnering With The Hospital, Fracture Care (Managing The Load, Intrusion From Non-Orthopedists), CompensationStrategies,Billing - Growth control strategies around the ankle - Case Discussion: Fibular deficiency, Deformity around the Ankle -BreakoutSession:Forefoot:LongitudinalEpiphysisBracket 4th Posi-Posna Workshop. Pune, India, January 13, 2012 - Management of the Knee and Crouch Gait in CP - Special Guest Lecturer. Acute Compartment Syndromes in Children: diagnosis and Treatment - Examination Under Anesthesia, Closed Reduction, Arthrography and Spica Application for DDH Curso Internacional Pe Infantil e do Adolescente Annual Meeting, Sao Paolo,Brazil,March16-17,2012 - Compartment syndrome - Management of CavoVarus Feet - Management of Tarsal Coalition - Management of the Foot in Cerebral Palsy - Management of Foot Deformities in Duchene Muscular Dystrophy -BracketEpiphysisoftheMetatarsal - Ankle Fractures: Prevention of Growth Plate Closures and Foot/ Ankle Deformity • • • • • • - Osteochondritis of the Foot - Tib-Fib Synostosis and effects on the Foot/Ankle Orthopedic Conference, Manaus, Brazil,March19-20,2012 - Compartment Syndromes - Tarsal Coalition ABJS Annual Meeting, Charleston, SC, May 3, 2012 - Contemporary Imaging for Tibial Tubercle Fracture Patterns in Adolescents: Need for Intra-articular Assessment POSNAAnnualMeeting,Denver,CO, May 17, 2012 - Risk Factors for Compartment Syndrome After Flexible Nailing of Pediatric Tibial Shaft Fractures -Lower Extremity/Neuromuscular Symposium - Flatfoot in Cerebral Palsy, the 3C Procedure - Salter-Harris II Fractures of the Distal Tibia: Does Surgical Management Reduce the Risk of Premature Physeal Closure? - Contemporary Imaging for Tibial Tubercle Fracture Patterns: Need for Intra-articular Assessment. e-Poster IPOTT Annual Meeting, Cannes, France, September 22, 2012 - Pathomechanics of Gowers’ Sign: A Video Analysis IPOS Annual Meeting, Orlando, FL, November 29, 2012 - My Pavlik Harness Protocol and What I do When it Fails - Resect a Tarsal Coalition - Tarsal Coalitions: Resect It & You’re Done: Leave it Flat. Adult vs. Ped. Smackdown: POV - Ponseti Casting: Initial Management.BreakoutSession -Ponseti Complex Problems. Breakout Session - Pediatric Foot: Surgery Management of Congenital and Acquired Conditions - Controversies – Is there an Answer. Moderator AAOS Annual Meeting, Chicago, IL, March 23, 2013 - Pavlik Harness Treatment: What to do and what not to do? - Infantile DDH: Screening, Safe-swaddling, Harness Application and Follow-up Protocol. Scientific Exhibit SE42 - Does Surgical Management Reduce the Risk of Premature Physeal Closure in Salter-Harris II Distal Tibia Fractures? Poster No. P492 • POSNA Annual Meeting, Toronto, Ontario, Canada, May 2, 2013 - Use of Mid-level Providers in Pediatric Orthopedics - Reliability of a New Radiographic Classification of Developmental Dysplasia of the Hip - Negotiation in Practice: How to Get BothWhatYouNeedandWhatYou Want - Steroid Injection for Unicameral BoneCystsoftheProximalHumerus in the Skeletally Immature - Does Portable Intraoperative CT Scan Improve the Quality of Talocalcaneal Coalitions? Paper Poster #20 Dennis R. Wenger, MD • 2011 MacLaggan Award for International Service to Children • Downtown San Diego Rotary Club, San Diego, CA • Teton Valley Pediatric Orthopedic Society Meeting, Driggs, ID, September 23-24, 2011 - The Osteochondroma Count in MHE: New Thoughts on Glycobiology, Spine Surgery and Ear Reconstruction–StrangeBedfellows • 19th Annual Meeting of the Iranian Orthopedic Association, Tehran, Iran, October 17-21, 2011 - Modern Management of LCPD: Advanced Containment Method-Triple Innominate Osteotomy - Management of SCFE In The Impingement Era - Management of Neuromuscular Hip - Approach To Re-Dislocation After DDH Treatment - Modern Management of LCPD - Surgical Management of Flat Foot Disorders & Tarsal Coalition • International Pediatric Orthopedic Think Tank, Sausalito, CA, October 20-22, 2011 - The Osteochondroma Count in MHE: New Thoughts on Glycobiology - Spine Surgery and Ear Reconstruc- Orthopedics & Scoliosis ortho surg v5.indd 40 1/23/14 4:45 PM tion–StrangeBedfellows • 8th Annual International Pediatric Orthopaedic Symposium, Orlando, FL, December 7-10, 2011 - Legg-Calve Perthes, ICL Instructor - Treating Severe Acetabular Dysplasia with the Triradiate Open, Invited Lecture - Case Discussion: Mature Perthes with Hip Pain, ICL Moderator - Pelvic Osteotomies – Hands On: Basic(Salter,Dega,Pemberton),ICL Instructor - Pelvic Osteotomies – Hands On: Advanced (Ganz, Triple, Others), ICL Instructor • American Academy of Orthopedic Surgeons Annual Meeting, San Francisco, February 7-11, 2012 - Managing Hip Dysplasia after Triradiate Closure – Treatment for the Adolescent and Young Adult, Instructional Course Lecture - Surgical Management of Hip Dislocation, Instructional Course Lecture • AAOS – TOTBID Lectures, Antalya, Turkey,April18-20,2012 - ESIN Method for Treating Childhood Femur Fractures - Forearm Fractures in Children - Principles in the Treatment of Perthes Sequelae • Pediatric Orthopedic Surgeons of North America (POSNA), Annual Meeting – Hip Course, Denver, CO, May 16, 2012 - Is There a Role for Acetabular Dysplasia Correction in an Asymptomatic Patient? • 5th Annual Kenneth G. Burton MD Visiting Professorship, University of Rochester, New York, October 16-18, 2012 - Will Your Child Live to be 100? Orthopedic Thoughts on the Demand for Musculoskeletal Perfection - Understanding and Treating Tarsal Coalition in Childhood – from R.I. Harris and the Canadian Army to Advanced 3D CT Imaging • International Pediatric Orthopedic Symposium (IPOS), Orlando, FL, November28-December1,2012 - Perthes – When to Operate? (Paper) - Challenging Decisions in Pediatric Hip Surgery (Panel Moderator) - Pelvic Osteotomies – Hands-on: Basic,PanelMember - How to Perform a Triple Innominate Osteotomy, Paper - Pelvic Osteotomies – Hands on: Advanced, Panel Member - Treating Complex Hip Disorders, Moderator - Pelvic Osteotomies – Hands on: Advanced, Panel Member • AmericanAcademyofOrthopedicSurgeons, Chicago, IL, March 20-22, 2013 - ICL 365: Current Perspectives on the Diagnosis and Management of DDH through Early Adulthood, Co-Moderator • POSNA Specialty Day – Chicago, IL, March 23, 2013 - Surgical Management of Hip Dislocation (DDH), Lecturer -Dysplasia Symposium - Case-Based Discussion (DDH), Moderator Henry G. Chambers, MD • Excellence in Philanthropy Award: Rady Children’s Hospital • BestDoctorsinSanDiego • BestDoctorsinAmerica • U.S.News&WorldReportTopDoctors • AmericanAcademyforCerebralPalsy and Developmental Medicine, Las Vegas, NV, October 2011 - Transcriptional Profile of Spastic Hamstring Muscles in Children with Cerebral Palsy • ASAP(AllianceforSurgeryandAnesthesia Presence) Global Surgery Conference, San Diego, CA, November 2011 - Orthopedic Surgery: Lessons learned from Haiti • AAOS/ POSNA International Pediatric Orthopedic Symposium, Orlando, FL, December 2011 - Cerebral Palsy and Gait Analysis - Prevention of Infections in Pediatric Orthopedic Surgery - Orthopediatrics Distal Femoral Extension Osteotomy Workshop - Orthopediatrics Proximal Femoral Blade Plate and Femoral Locking Plate Workshop - Orthopediatrics Miserable Malalignment Workshop - Cerebral Palsy Session: Hip and Foot - Treatment of Tibial Eminence Fractures - Sports Injuries in Children: Panel - Treatment of Spasticity in Children with Cerebral Palsy - Treatment of Rectus Femoris Spasticity: Transfer vs Release • Society of Military Orthopedic Surgeons (SOMOS) Annual Meeting, San Diego, CA, December 2011 - Pediatric Knee Problems - Moderator of Pediatric Papers • Rocky Mountain Hospital for Children: Pediatric Sports Medicine and TraumaSymposium,BeavrCreek,CO, January 2012 - Tibial Tubercle Fractures • American Academy of Orthopedic Surgeons Annual Meeting, San Francisco, CA, February 2012 - Sports Medicine Problems in Children and Adolescent - Osteochondritis Dissecans of the Knee • POSNA/AOSSM Specialty Day, San Francisco, CA , February 2012 - Treatment of Anterior Knee Pain in Children and Adolescents • PediatricandAdolescentSportsMedicine, San Diego, CA, March 2012 , Course Co-Director, Moderator of Orthopedic Section - The Knee in Pediatric and Adolescent Sports - Developmental and Psychological Aspects of Pediatric Sports Medicine • Southern California Conference for Adults with Cerebral Palsy, Rancho Los Amigos National Rehabilitation Hospital, Downey, CA, March 2012 -BonesandGroans:AgingwithCerebral Palsy •SportsSymposium,PediatricOrthopedic Society of North America, Denver, CO, May 2012 - The Future of Pediatric Sports Medicine: Panel Member - Update on Patellofemoral Disorders in Children • GCMAS Symposium: Clinical Applications and Impact of Comprehensive Motion AnalysisAmerican Academy for Cerebral Palsy and Developmental Medicine, Toronto, Ontario, Canada, September 2012 Orthopedics & Scoliosis ortho surg v5.indd 41 41 1/23/14 4:45 PM - The Impact of Motion Analysis on the Treatment of Movement Disorders: The Last 30 Years • American Academy for Cerebral Palsy and Developmental Medicine, Toronto, Ontario, Canada, September 2012 - Orthopedic Surgery for Adults with Cerebral Palsy -KneeandFoot/AnkleSurgery • American Academy of Orthopedic Surgery West Coast Maintenance of Certification (MOC) Review Course, San Francisco, CA, November 2012 - Pediatric Lower Extremity Problems - Neuromuscular Diseases - Growth Disturbances - Panel on Pediatric Topics • AAOS/ POSNA International Pediatric Orthopedic Symposium, Orlando, FL, December 2012 - Orthopediatrics Distal Femoral Extension Osteotomy Workshop - Orthopediatrics Proximal Femoral Blade Plate and Femoral Locking Plate Workshop - Orthopediatrics Miserable Malalignment Workshop - Imaging and Classification of OCD - Sports Injuries in Children: Panel -BracingandSpasticityManagement in Children with CP: Moderator - Treatment of Rectus Femoris Spasticity: Transfer vs Release • 1stCerebralPalsyConference,Rizzoli Institute,Bologna,Italy,Feb2013 - Cerebral Palsy - Treatment of Hip Disorders in Cerebral Palsy - Workshop on Femoral Osteotomies in Cerebral Palsy • AucklandPediatricOrthopedicSurgery Symposium, Auckland, NZ, April 2013 - Update on Advances in Cerebral Palsy and Sports Medicine • Sydney Pediatric Orthopedic Review, Sydney, NSW, Australia, April 2013 - Gait Analysis for Dummies - Aetiology and Classification of Cerebral Palsy - Case reviews of patients with Cerebral Palsy • PediatricOrthopedicSocietyofNorth America, Toronto, Ontario, Canada, May 2013 42 - Treatment of Patellofemoral Instability in Adolescents - Section Director of Neuromuscular and Lower Extremity Specialty Day - Treatment of GMFCS III Cerebral Palsy Peter O. Newton, MD • President of the Pediatric Orthopedic Society of North America (POSNA); May 2012-May 2013 • Basic Science Award Paper, 3D Visualization Of The Vertebral Growth Plate: The Effects Of Growth Modulation. Newton, Doan, Glaser, Farnsworth. Pediatric Orthopedic Society of North America (POSNA) Annual Meeting, Toronto, CA, May 2013 • International Pediatric Orthopedic Symposium, Orlando, FL, December 8-10,2011 - Surgical Treatment of High Grade Spondylolisthesis - Surgical Site Infection Project at Rady Children’s Hospital San Diego • PediatricOrthopaedicSocietyofNorth America Specialty Day. AAOS Meeting, San Francisco, CA, February 11, 2012 - Technique Update: Vertebral Column Resection • 19th Annual Meeting of the Iranian Orthopedic Association, Tehran, Iran, October 17-21,2011 - Early Onset Scoliosis • 25th Annual Meeting of Association of Spinal Surgeons in India, February 24, 2012 - Early Onset Scoliosis: Surgical Treatment - Preventing Neurologic Complication in Spondylolisthesis Surgery • PeertoPeerDeformity:StrategyofEOS, Beijing,China,April22,2012 - Key Note lecture, Challenges in EOS BurtYaszay,MD • SRS outcome scores are sensitive to both the occurrence and resolution of a complication in the surgical treatment of AIS. SRS, September 2012 (Poster, Goldstein Award Nominee) • Lenke 1C and 5C spinal deformities fused selectively: A natural history of uninstrumented compensatory curves. POSNA, May 2012 (Oral, Clinical Award Nominee) • Determining optimal post-operative • • • • coronal parameters for selective thoracic fusion. POSNA, May 2013 Better understanding postoperative changes in adolescent idiopathic scoliosis using 3D reconstructions. AAOS, March 2013 - What do coronal flexibility films really tell us about the treatment of idiopatic early onset scoliosis patients using growing rods? ICEOS, November 2012 - EOS-Imaging is available for early-onset scoliosis patients and can reduce their ionizing radiation exposure -Biomechanical evaluation of 4 different foundation constructs commonly used in growing spine surgery: are rib anchors comparable to spine anchors - Limited anterior spinal fusion: an effective strategy in controlling progressive early onset scoliosis - Recommendations for patients and families after growing rod surgery: surgeon agreement on post-operative care Selective thoracic fusion in adolescent idiopathic scoliosis curves with a c lumbar modifier: which rules can be broken? SRS, September 2012 - The prevalence of postoperative pain in adolescent idiopathic scoliosis and the association with preoperative pain - Wound infections after spine deformity correction cerebral palsy: risk factors - Surgical Outcomes in Adolescent Idiopathic Scoliosis with or without spondylolisthesis Analyzing the relationship between apical vertebral rotation and truncal rotation in AIS using 3D reconstructions. IMAST, July 2012 -Better understanding postoperative changes in adolescent idiopathic scoliosis using 3D reconstructions of 2D radiographs - Longitudinal analysis of radiation exposure during the course of growing rod treatment for early onset scoliosis Lenke 1C and 5C spinal deformities fused selectively: A natural history Orthopedics & Scoliosis ortho surg v5.indd 42 1/23/14 4:45 PM of uninstrumented compensatory curves. POSNA, May 2012 • Should shoulder balance determine proximal fusion levels in patients with Lenke 5 curves? AAOS February 2012 - Are thoracic curves with a low apex (T11orT11/12)reallythoraciccurves? - Restoring thoracic kyphosis during posterior instrumentation for adolescent idiopathic scoliosis Eric W. Edmonds, MD • HonoraryMember,ASociedadeBra- sileira de Ortopedia PediГЎtrica, 2013 South America Traveling Fellowship, Pediatric Orthopaedic Society of North America, 2011 POSNA Biomet South American Traveling Fellowship, 2011 HonoraryMember,ASociedadeBrasileira de Ortopedia PediГЎtrica, 2013 Fellow, South America Traveling Fellowship, Pediatric Orthopaedic Society of North America, 2011 POSNA Biomet South American Traveling Fellowship 2011 2013 Annual Meeting of the American Orthopedic Society of Sports Medicine, Chicago, IL - Normal Parameters of Skeletally Immature Knees: Developmental Changes on Magnetic Resonance Imaging 2013AnnualMeetingofthePediatric Orthopaedic Society of North America, Toronto, Canada - Results Of Displaced Tibial Spine Fractures: A Comparison Between Open, Arthroscopic, And Closed Management 2012AmericanAcademyofPediatrics National Conference and Exhibition in New Orleans, LA - Elbow Fractures in Childhood Obesity: Lateral Condyle vs Supracondylar Humerus Fractures 2012 Annual Meeting of the Association of Bone and Joint Surgeons, Charleston, SC - Contemporary imaging for tibial tubercle fracture patterns in adolescents: Need for intra-articular assessment 2012AnnualMeetingofthePediatric Orthopaedic Society of North America, Denver, CO • Fellow, • • • • • • • • • - Management Of Rotator Cuff Tears In Adolescents: Factors Affecting Patient Outcomes - Risk Factors for Compartment Syndrome After Flexible Nailing of Pediatric Tibial Shaft Fractures • 2012AnnualMeetingoftheAmerican Academy of Orthopaedic Surgeons, San Francisco, CA - Adolescent rotator cuff tears - Immediate Intramedullary Flexible Nailing of Open Pediatric Tibial Shaft Fractures. Determining Displacement in Medial Epicondyle Humerus Fractures. - Effects Of Surgical Treatment for Recurrent Patella Instability in Adolescent Patients On Knee Extensor Mechanics • 2011AnnualMeetingofthePediatric Orthopaedic Society of North America, Montreal, Quebec, Canada - Children With Anterior Shoulder Instability: Do Not Underestimate the Extent of Labral Pathology • AndrewT.Pennock,MD • Pediatric Orthopedic Society of North America (POSNA) Annual Meeting, Winner of the James Kasser, MD Outstanding ePoster Award – Spectrum of Hip Impingement Morphology in Adolescents:AnEOSBasedDouble-Cohort Study, Clinical Award Paper Nominee: Salter-Harris II Fractures of the Distal Tibia: Does Surgical Management Reduce the Risk of Premature Physeal Closure? Toronto, CA, May 2013 • American Academy of Pediatrics (AAP) National Conference, Orlando, FL, October 26-29, 2013 - The Spectrum Of Hip Impingement Morphology in Adolescents and Young Adults • InternationalCartilageRepairSociety (ICRS) Annual Meeting Izmir, Turkey, September16-18,2013 - Osteochondral Allograft Transplantation of the Knee in the Pediatric and Adolescent Population • American Orthopaedic Society for Sports Medicine (AOSSM) 2013 Annual Meeting, Chicago, IL, July 11-14, 2013 - Osteochondral Allografts For Knee Lesions In The Pediatric And Adoles- • • • • cent Population. Does one size fit all: Variation in tibial tubercle trochlear groove (TTTG) measuements as a function of age, size, and patella instability? PediatricOrthopaedicSocietyofNorth America (POSNA) 2013 Annual Meeting, Toronto, Ontario, May 1-4, 2013 - Does Portable Intraoperative Ct Scan Improve The Quality Of Talocalcaneal Coalition Resection - Previously Described Radiographic Parameters Of Femoroacetabular Impingement Are Common In Asymptomatic Patients - At What Age Do Cam and Pincer Morphology Become Apparent: An Analysis of 225 Pediatric And Adolescent CT Scans? - Potential Causes of Loss of Reduction in Supracondylar Humerus Fractures. Arthroscopic Evaluation Of Meniscus Tear Patterns In Pediatric And Adolescent Patients - Functional And Radiographic Outcomes 1 After Non-Operative Treatment Of Displaced Adolescent Clavicle Fractures - Results Of Displaced Tibial Spine Fractures: A Comparison Between Open, Arthroscopic, And Closed Management 54thAnnualSocietyofMilitaryOrthopaedic Surgeons (SOMOS) Meeting. Naples, FL. December 10-14, 2012 - The Hips Antero-Superior Labral Tear with Avulsion of the Rectus Femoris (HALTAR) Lesion: Does the SLAP Equivalent in the Hip Exist? American Academy of Orthopaedic Surgeons (AAOS) 2013 Annual Meeting, Chicago, IL, March 19-23, 2013 - Does Surgical Management Reduce the Risk of Premature Physeal Closure in Salter-Harris II Distal Tibia Fractures? International Society for Hip Arthroscopy (ISHA) Annual Scientific Meeting. Boston,MA,September24-26,2012 - Cam pathology in pediatric patients InternationalCartilageRepairSociety (ICRS) Annual Meeting. Montreal, Canada, May 12-15, 2012 - Comprehensive Arthroscopic Management (CAM) Survivorship: Alternative to Arthroplasty in Active Patients with Advanced Shoulder Osteoarthritis Orthopedics & Scoliosis ortho surg v5.indd 43 43 1/23/14 4:45 PM PUBLICATIONS Chambers H, Shea K, Carey J. AAOS Clinical Practice Guideline: Diagnosis and treatment of osteochondritis dissecans. J Am Acad Orthop Surg, 19(5):307-9, 2011. Clements D, Marks M, Newton P, Betz R, Lenke L, Shufflebarger H, Harms Study Group. Did the Lenke classification change scoliosis treatment? Spine (Phila Pa 1976), 36(14):1142-5, 2011. Newton P, Farnsworth C, Upasani V, Chambers R, Varley E, Tsutsui S. Effects of intraoperative tensioning of an anterolateral spinal tether on spinal growth modulation in a porcine model. Spine (Phila Pa 1976), 36(2):109-17, 2011. Edmonds E. No difference in improvement in physical function between splint and cast at 6 weeks in children with minimally angulated fractures of the distal radius. Evid Based Med, 16(2):49-50, 2011. Hosalkar H, Wenger D. Nonaccidental trauma in children: editorial comment. Clin Orthop Relat Res, 469(3):751-2, 2011. DalalA,UpasaniV,BastromT,YaszayB, Shah S, Shufflebarger H, Newton P. Apical vertebral rotation in adolescent idiopathic scoliosis: comparison of uniplanar and polyaxial pedicle screws. J Spinal Disord Tech, 24(4):251-7, 2011. Chambers H, Shea K, Anderson A, BrunelleT,CareyJ,GanleyT,Paterno M, Weiss J, Sanders J, Watters W 3rd, Goldberg M, Keith M, Turkelson C, WiesJ,RaymondL,BoyerK,Hitchcock K,AndersonS,SlukaP,BooneC,Patel N, American Academy of Orthopedic Surgeons. Diagnosis and treatment of osteochondritis dissecans. J Am Acad Orthop Surg, 19(5):297-306, 2011. Mubarak S, Dimeglio A. Navicular excision and cuboid closing wedge for severe cavovarus foot deformities: a salvage procedure. J Pediatr Orthop, 31(5):551-6, 2011. Newton P, Farnsworth C, Upasani V, Chambers R, Yoon S, Firkins P. Dual and single memory rod construct comparison in an animal study. Spine (Phila Pa 1976), 36(14):E904-13, 2011. Moraleda L, Mubarak S. Flexible flatfoot: Differences in the relative alignment of 44 each segment of the foot between symptomatic and asymptomatic patients. J Pediatr Orthop,31(4):421-8,2011. PandyaN,BaldwinK,KamathA,Wenger D, Hosalkar H. Unexplained fractures: Child abuse or bone disease? A systematic review. Clin Orthop Relat Res, 469(3):805-12,2011. Price C, Thompson G, Wenger D. Containment methods for treatment of Legg-CalvГ©-Perthes disease. Orthop Clin North Am, 42(3):329-40, 2011. Gannotti ME, Minter CL, Chambers HG, Smith PA, Tylkowski C. Self-concept of adults with cerebral palsy. Disabil Rehabil, 33(10):855-61,2011. Smith L, Lee K, Ward S, Chambers H, Lieber R. Hamstring contractures in children with spastic cerebral palsy result from a stiffer extracellular matrix and increased in vivo sarcomere length. J Physiol,589(Pt10):2625-39,2011. Takahashi J, Newton P, Ugrinow V, Bastrom T. Selective thoracic fusion in adolescent idiopathic scoliosis: Factors influencing the selection of the optimal lowest instrumented vertebra. Spine (Phila Pa 1976), 36(14):1131-41, 2011. Mubarak SJ, Dimeglio A. Navicular excision and cuboid closing wedge for severe cavovarus foot deformities: a salvage procedure. J Pediatr Orthop. 31(5):551-6, 2011. Price CT, Thompson GH, Wenger DR. Containment methods for treatment of Legg-CalvГ©-Perthes disease. Orthop Clin North Am. 42(3):329-40, 2011, vi. Review. Tsutsui S, Pawelek JB, Bastrom TP, Shah SA, Newton PO. Do discs “open” anteriorly with posterior-only correction of Scheuermann’s kyphosis? Spine (Phila Pa1976).36(16):E1086-92,2011. Upasani VV, Farnsworth CL, Chambers RC, Bastrom TP, Williams GM, Sah RL, Masuda K, Newton PO. Intervertebral disc health preservation after six months of spinal growth modulation.JBoneJointSurgAm.2011Aug 3;93(15):1408-16. Yaszay B, O’Brien M, Shufflebarger HL, Betz RR, Lonner B, Shah SA, Boachie-AdjeiO,CrawfordA,LetkoL, Harms PJ, Gupta MC, Sponseller PD, Abel MF, Flynn J, Macagno A, Newton PO. Efficacy of Hemivertebra Resec- tion for Congenital Scoliosis (CS): A Multicenter Retrospective Comparison of Three Surgical Techniques. Spine (Phila Pa 1976). 2011 Sep 8. [Epub ahead of print]. Wenger DR, Pandya NK. A brief history of Legg-CalvГ©-Perthes disease. J Pediatr Orthop. 31(2 Suppl):S130-6, 2011. Review. Wenger DR, Pandya NK. Advanced containment methods for the treatment of Perthes disease: Salter plus varus osteotomy and triple pelvic osteotomy. J Pediatr Orthop, 31(2 Suppl):S198-205, 2011. Review. Cidambi KR, Glaser DA, Bastrom TP, Nunn TN, Ono T, Newton PO. Postoperative changes in spinal rod contour in adolescent idiopathic scoliosis: an in vivo deformation study. Spine (Phila Pa 1976),15;37(18):1566-72,2012. Glaser DA, Doan J, Newton PO. Comparison of 3-dimensional spinal reconstruction accuracy: biplanar radiographs with EOS versus computed tomography. Spine (Phila Pa 1976), 37(16):1391-7, 2012. Franko OI, Bray C, Newton PO. Validation of a scoliometer smartphone app to assess scoliosis. J Pediatr Orthop. 2(8):e72-5,2012. Sanders JO, Newton PO, Browne RH, HerringAJ:Bracinginadolescentidiopathic scoliosis, surrogate outcomes, and the number needed to treat. J Pediatr Orthop, 32 Suppl 2:S153-7, 2012. OnoT,BastromTP,NewtonPO.Defining 2 components of shoulder imbalance: clavicle tilt and trapezial prominence. Spine (Phila Pa 1976), 37(24) E1511-6, 2012. NewtonPO,BastromTP,EmansJB,Shah SA, Shufflebarger HL, Sponseller PD, Sucato DJ, Lenke LG. Antifibrinolytic agents reduce blood loss during pediatric vertebral column resection procedures. Spine (Phila Pa 1976). 37(23) E1459-63, 2012. MiyanjiF,SlobogeanGP,SamdaniAF,Betz RR,ReillyCW,SlobogeanBL,Newton PO. Is larger scoliosis curve magnitude associated with increased perioperative health-care resource utilization?: a multicenter analysis of 325 adolescent idiopathic scoliosis curves. J Bone Joint Surg Am,94(9):809-13,2012. Orthopedics & Scoliosis ortho surg v5.indd 44 1/23/14 4:45 PM LiuRW,YaszayB,GlaserD,BastromTP, Newton PO. A method for assessing axial vertebral rotation based on differential rod curvature on the lateral radiograph. Spine (Phila Pa 1976), 37(18)E1120-5,2012. 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Vertebral column resection in children with neuromuscular spine deformity. Spine (Phila Pa 1976), 37(11) E655-61, 2012. Sponseller PD, Flynn JM, Newton PO, MarksMC,BastromTP,Petcharaporn M, McElroy MJ, Lonner BS, Betz RR. Harms Study Group: The association of patient characteristics and spinal curve parameters with Lenke classification types. Spine (Phila Pa 1976), 37(13)1138-41,2012. Dhawale AA, Shah SA, Sponseller PD, BastromT,NeissG,YorgovaP,Newton PO, Yaszay B, Abel MF, Shufflebarger H, Gabos PG, Dabney KW, Miller F. Are antifibrinolytics helpful in decreasing blood loss and transfusions during spinal fusion surgery in children with cerebral palsy scoliosis? Spine (Phila Pa 1976), 37(9)ES49-55, 2012. Marks M, Newton PO, Petcharaporn M, Bastrom TP, Shah S, Betz R, Lonner B, Miyanji F. Postoperative segmental motion of the unfused spine distal to the fusion in 100 patients with adolescent idiopathic scoliosis. Spine (Phila Pa1976),37(10)826-32,2012. 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J Pediatr Orthop, 32 Suppl2:S187-92,2012. Smith LR, Chambers HG, Subramaniam S, Lieber RL. Transcriptional abnormalities of hamstring muscle contractures in children with cerebral palsy. PLoS One, 7(8):e40686,2012.doi:10.1371/journal. pone.0040686.Epub2012Aug16. Chambers HG, Shea KG, Anderson AF, JojoBrunelleTJ,CareyJL,GanleyTJ, Paterno M, Weiss JM, Sanders JO, Watters WC 3rd, Goldberg MJ, Keith MW, Turkelson CM, Wies JL, Raymond L, Boyer KM, Hitchcock K, Sluka P, BooneC,PatelN,AmericanAcademy of Orthopaedic Surgeons. American Academy of Orthopaedic Surgeons clinical practice guideline on: the diagnosis and treatment of osteochondritis dissecans. J Bone Joint Surg Am, 18;94(14):1322-4,2012. TisJE,EdmondsEW,BastromT,Chambers HG. Short-term results of arthroscopic treatment of osteochondritis dissecans in skeletally immature patients. J Pediatr Orthop, 32(3):22631, 2012. ChambersHG, BeckerRE,HoffmanMT, Hartley-McAndrew M, Stein MT. 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Orthopedics & Scoliosis ortho surg v5.indd 47 47 1/23/14 4:45 PM Pediatric Otolaryngology The Division of Pediatric Otolaryngology at Rady Childrens Specialists of Diego (RCSSD) manages complex tertiary care otolaryngologic disorders, including: congenital and acquired hearing loss in children; airway problems ranging from obstructive sleep apnea to complicated diseases of the laryngeal and tracheal airway requiring cutting edge surgical intervention and reconstruction; complications of acute sinusitis that involve the eye and brain; chronic sinusitis problems in children including those with cystic fibrosis; congenital abnormalities of the face and neck, including complex vascular malformations; congenital and acquired thyroid disease; and a host of communication, speech and voice disorders. The Division also leads a variety of interdisciplinary teams, including the Pediatric Airway and Aerodigestive Team, Cochlear Evaluation and Implementation Team, and Voice Disorders in Children and Thyroid Tumor Board. All of the physicians in the Division are fellowship trained in pediatric otolaryngology, which requires completion of an otolaryngology residency, plus a minimum of one additional year of specialty training. This advanced training is focused completely on the unique diagnostic and treatment issues in children from birth to 19 years of age. The Division of Pediatric Otolaryngology has been a source of leadership and innovation for over 30 years. With its commitment to ongoing patient care, physician education and research at the highest of levels, the Division will continue to enhance its expertise and devotion to state-of-the-art therapy for children with hearing and speech impairment, infectious diseases of the head and neck, and complex airway and head and neck abnormalities. otolaryngology v5.indd 48 1/23/14 4:46 PM FACULTY Seth M. Pransky, MD, Director, Division of Pediatric Otolaryngology; Director, Satellite Services RCHSD; Clinical Professor of Surgery, UCSD Marcella Bothwell, MD, Director, Pediatric Airway and Aerodigestive Team, RCHSD; Clinical Professor of Surgery, UCSD Daniela S. Carvalho, MD, Section Chief, Otolaryngology-RCHSD; Director, Hearing Program; Director, Pediatric Otolaryngology Fellowship Program; Clinical Professor of Surgery, UCSD Wen Jiang, MD, Director, Pediatric Thyroid Clinic; Co-Director Speech and Voice Clinic; Assistant Clinical Professor of Surgery, UCSD Donald B. Kearns, MD, Chief Medical Officer-RCHSD; Clinical Professor of Surgery, UCSD Shelby Leuin, MD, Director, ENT Resident Training Program; Co-Director Speech and Voice Clinic; Assistant Clinical Professor of Surgery, UCSD Anthony Magit, MD, Director, Inpatient Surgical Services, RCHSD; Director, Institutional Review Board-RCHSD; Clinical Professor of Surgery, UCSD Denise Lago, PAC Pam Salgado, PAC CLINICAL ACTIVITIES The Division’s physicians are responsible for covering the Emergency Department at RCHSD and running the Consultation Service for patients admitted to the hospital with ear, nose, throat, airway and neck abnormalities. The bulk of clinical practice is carried out on the campus of RCHSD combined with daily patient activity at satellite locations in Encinitas, Escondido Murrieta, and Oceanside. In addition, consultative services are provided to multiple regional Neonatal Intensive Care facilities including Sharp Mary Birch, Scripps La Jolla, Scripps Encinitas and UCSD Medical Center. Patients requiring operative intervention or specialized testing are brought to RCHSD. From 2011-2013 the Division conducted over 45,000 patient visits and carried out approximately 9000 operative procedures. Procedures included: • Placing ear tubes, removing tonsils and adenoids, restoring hearing with ossicular reconstruction, and the state of the art cochlear implant and Bone Anchored Hearing Aid program • Diagnostic and therapeutic endoscopic airway procedures from neonates to adolescents and open surgical management of complex airway diseases • Endoscopic sinus surgery for children with chronic sinusitis and complications of acute sinusitis; management of various intranasal abnormalities including turbinate malformations, septal deviations, bony nasal deformities, and open rhinoplasty for complex nasal obstruction and nasal tumors; management of the nasal and sinus manifestations of cystic fibrosis LEFT TO RIGHT: Daniela Carvalho, Wen Jiang, Seth Pransky, Marcella Bothwell, Anthony Magit, Shelby Leuin Pediatric Otolaryngology otolaryngology v5.indd 49 49 1/27/14 10:54 AM • Surgicalcorrectionofavarietyofcongenital head and neck malformations and management of both benign and malignant head and neck neoplasms with a focus on thyroid abnormalities and lymphatic malformations The Divisionrrection of a variety of congenital head and neck malformations and management of both benign and malignant head and neck neoplasms with a focus on thyroid abnormalities and lymphatic malpapillomatosis attracts patients from California, Nevada, Arizona, Mexico and the Pacific Rim countries for specialized pediatric ENT care. Marcella Bothwell, MD Marcella joined our department in 2007. She comes from the University of Missouri, where she was there for 6 years. She is now a Clinical Professor, Department of Surgery UCSD and a student at the Rady School of Management. Biomedical research is an avid interest for Dr. Bothwell and she has collaborated with the La Jolla Allergy and Immunology Institute for research on the etiology of recurrent tonsillitis and the body’s follicular T helper cell response in hopes of vaccine development. Because of this partnership, she became very interested in the ethics of human tissue research and in 2012 wrote an article for the Rady Business Journal with her coauthor and Rady School of Management Professor Erez Yoeli, PhD, Biotechnology consult: What does economics teach us about how to assign property rights for human tissue?. At RCHSD she developed and directs the Pediatric Airway and Aero digestive Team (PAAT), a multidisciplinary group that sees about 50 new patients each year with complex airway, swallowing and feeding problems. Dr. Bothwell is also quite active in the regional and national ENT community where she is Immediate Past President of the San Diego Academy of Otolaryngology. She is also the Immediate Past Chair for the ENTPAC and travels to Washington DC at least 2 times per year to lobby Congress about concerns in patient care. Finally Marcella has made three trips to Vietnam with REI International for a medical/surgical mission trip. 50 Daniela Carvalho, MD Daniela joined our department in 2003, having completed a two-year fellowship with our group from 1999-2001. She has worked as the Section Chief for Otolaryngology at RCHSD since 2009. Daniela’s clinical focus and area of interest is hearing in children including sensorineural, conductive and genetic hearing loss. As the director of the Hearing Program and lead surgeon for the RCHSD Cochlear Implant team, Daniela assesses hearing loss patients and guides the Team in management of more than 300 cochlear implant patients. This past year she successfully performed about 40 cochlear implants, including the most state of the art implants from three different implant brands. She continues to bring to our pediatric hearing-impaired patients state-of-the-art innovations in the area of implantable hearing devices, including the BAHA, Ponto-pro and Sophono devices (she performed the first pediatric Sophono implant in Southern California). Daniela has been the co-director of our Pediatric Otolaryngology Fellowship program and was responsible for successfully having our program accredited by the ACGME. She is involved in multiple international endeavors including ongoing lectures in her native Brazil through the Brazilian National ENT Association and her role as international liaison for SENTAC. She is the only female physician who is a member of the International Working Group on Endoscopic Ear Surgery. She is also very active in the American Society of Pediatric Otolaryngology as the chairperson for the Long Range Strategic Planning Committee.. Wen Jiang, MD Wen joined our department in 2007 and was accepted this year as a member to the American Society of Pediatric Otolaryngology. She continues her head and neck oncology practice with a special interest in thyroid neoplasms in children. Together with the department of Endocrinology, she has created a multi-disciplinary thyroid tumor board to discuss the management of patients with thyroid pathology. She has been twice awarded the RCHMF physician development grant to attend the inter- national American Thyroid Association meeting and was recently accepted as a member to the American Thyroid Association. Her listing on the ATA website for patient referral has put Rady Children’s hospital on the national map for thyroid disorders. Currently Wen is finishing an IRB approved retrospective review of our institutional experience in thyroidectomy patients over the last 10 years. A second specialized focus for Dr. Jiang is in voice disorders in children. She currently co-directs the Speech and Voice Endoscopy Clinic, a multi-disciplinary voice and speech team working closely with the Speech Pathology department at RCHSD. This team continues to provide comprehensive service to children with speech related disorders such as hypernasality and/or velopharyngeal incompetence, and other voice disorders. Wen has partnered with the emergency department to prospectively study the accuracy of metal detectors in detection and localization of metallic esophageal foreign bodies. The goal is to utilize metal detectors to minimize radiation exposure and to expedite the triage of these patients in the emergency room. Dr. Jiang is the our Division’s medical informatics champion and is currently heading the effort for our EPIC optimization process to make the overall physician workflow more efficient while maximizing the utility of our electronic medical records. Donald B. Kearns, MD Donald has practiced Pediatric Otolaryngology at RCHSD for 25 years. He completed the Master of Medical Management program at the Marshall School of Business at the University of Southern California in 2008. His primary interest is in administrative medicine. He currently serves as the Interim Surgeon in Chief for RCSSD and is the Chief Medical Officer and Senior Vice President for Health Affairs for Rady Children’s Hospital San Diego. Shelby Leuin, MD Shelby is the newest addition to the Pediatric Otolaryngology group at RCHSD, joining the practice in January 2011. She did her residency training at the Harvard Combined Otolaryngology Program and Pediatric Otolaryngology otolaryngology v5.indd 50 1/23/14 4:46 PM otolaryngology v5.indd 51 1/23/14 4:46 PM her pediatric otolaryngology fellowship training at the University of Colorado, Denver Children’s Hospital. Her clinical interests focus on midfacial abnormalities including congenital and acquired nasal deformities, cleft palate and velopharyngeal insufficiency, as well as airway anomalies and reconstruction. She adds a unique skill set to our group with her training and interest in functional rhinoplasty. She has been awarded two Physician Development Grants to attend courses and symposia on rhinoplasty and has been actively building her practice in this area. Shelby is co–director of the Speech and Voice Endoscopy Clinic and participates actively in the Cleft Palate and Craniofacial clinics. In this capacity, she provides the unique ability to provide continuity of care for these patients by both performing the office nasal endoscopy in collaboration with the speech language pathologists as well as performing the speech surgery for velopharyngeal insufficiency. On a national level Dr. Leuin has been selected to be a member of the American Academy of Otolaryngology Pediatric Otolaryngology Education Committee and as such has published education materials on pediatric sinusitis. Locally, she is collaborating with Jane Burns, M.D. on a study evaluating the laryngeal findings associated with hoarseness in children with Kawasaki disease. The findings have been presented at both national and international meetings and have also recently been published. Dr. Leuin is also the Director of the Pediatric Otolaryngology residency-training program. She has presented at Grand Rounds and multiple CME courses, as well as at morning conference for the otolaryngology residents. She actively mentors the group’s Physician Assistant in publishing and presenting at several national meetings. Anthony E. Magit, MD Anthony has been a part of our group for 19 years. He is currently serving as the immediate past chief of staff of RCHSD and is the Chairman of the RCHSD Institutional Review Board. Anthony’s ongoing areas of clinical and research interests include lymphatic malforma52 tions, cystic fibrosis and obstructive sleep disorders in infants and children. He continues to collaborate with the Pulmonary Division and has been involved in investigating a novel approach for treating patients with lymphatic malformations as well has having treated more than 160 patients with lymphatic malformations from the Southwestern region of the United States and Northern Mexico. Superimposed on a full clinical practice and his administrative duties, Anthony is President of the Society for Ear, Nose and Throat Advances in Children and earned his Masters in Public Health from the Johns Hopkins Bloomberg School of Public Health in May, 2012. Anthony’s involvement with representing RCHSD and pediatric medicine include membership on the Board of the San Diego County Medical Society and the Children’s Specialty Care Coalition. Seth M. Pransky, MD Seth began practice at RCHSD in 1985 and became the Division Director for Pediatric Otolaryngology in 1997. At RCHSD he is the Director of Satellite Services and chairs the Clinical Practice Committee and is the CME Director for the Regional Practical Pediatrics courses. His ongoing areas of clinical interest include issues related to airway diseases and endoscopic management of these problems,, operative management of nasal and sinus disease in children and issues related to tympanostomy tube utilization. He lectures extensively throughout the United States and internationally on these and other topics. In 2008 Seth received the Gabriel F. Tucker Award from the American Laryngological Association for outstanding contributions to Pediatric Laryngology. In 2011 he was awarded the prestigious Ray Skoglund Excellence in Teaching Award from RCHSD. In 2013 he received the Chevalier Jackson award from the American Bronchesophagologic Association for Outstanding Achievement and Accomplishment in Bronchoesophagology, In addition to his local responsibilities, Seth has been involved nationally with board positions in the American Society of Pediatric Otolaryngology and the American Academy of Pediatrics ENT Section and was recently the President of the Soci- ety of Ear, Nose and Throat Advances in Children. RESEARCH ACTIVITIES For the past 28 years, the Division has been recognized around the world for innovative research and advancements in managing a variety of pediatric airway abnormalities. Procedures include corrective open laryngotracheal reconstruction and therapeutic endoscopic management of airway abnormalities using innovative lasers, debriders and injectable medications. Current research projects involve all aspects of pediatric otolaryngology including cochlear implant issues, head trauma, head and neck tumor management in children, lymphatic malformations treatment, acute and chronic sinusitis research and outcomes of sinus surgery, and more unusual problems such as lack of sense of smell in children, hoarseness in patients with Kawasaki’s Disease and resolution of recurrent fever after tonsillectomy in patients with Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis (PFAPA) Syndrome. The active research projects are: • OralLanguageCapabilitiesofMonolingual and Bilingual Spanish and English Speaking Children with Cochlear Implants • Epidemiology of skull base fractures in San Diego County • Managementoflymphaticmalformations: A database protocol • Multi-Institutional study of Picibanil for Lymphatic Malformations • SystematicReviewofsinussurgeryin patients with Cystic Fibrosis • Anosmiainthepediatricpopulation • Salivaryglandtumorsinthepediatric populations • HoarsenessinKawasakiPatients • Cellular Immunity in Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis (PFAPA) Syndrome • Ten year retrospective review of orbital complications of acute sinusitis at RCHSD • Pharyngeal probe for Extra esophageal reflux • Prospective assessment of Ankyloglossia and response to Frenulotomy • Comparison of non-verbal cognitive function in patients with hearing loss of various etiologies Pediatric Otolaryngology otolaryngology v5.indd 52 1/23/14 4:46 PM • The Respective Contributions of Computed Tomography and Magnetic Resonance Imaging in Cochlear Implant Pre-Operative Planning in Academic Institutions • Ten year retrospective review of thyroid neoplasms in the pediatric population • TheroleofmetaldetectorsintheED for esophageal foreign bodies detection and expedited management TEACHING ACTIVITIES Superimposed on clinical care is the Division of acute sinusitis at RCHSDFAPA) S two fellows in our clinical Pediatric Otolaryngology fellowship program. Since 1990, we have graduated 29 fully-trained pediatric otolaryngologists who have gone on to productive careers in academic institutions throughout the United States. In addition, the Division is responsible for educating ENT residents from the UCSD and the Naval Medical Center San Diego programs in pediatric otolaryngology. Pediatric residents, family medicine residents and medical students and nurse practitioner students also rotate through the clinic and receive didactic lectures from our staff as part of their pediatric specialty education program. The Division actively participates in community outreach programs through involvement with the health professionals mentor program at UCSD and through its involvement with the otology and hearing clinic for San Diego City Schools. Physicians from around the world enjoy the opportunity for observational preceptorships with physicians from Brazil, Peru, Mexico, Chile, Venezuela, Vietnam and Iraq having spent time at RCHSD in recent years. Throughout the year, members of the Division give Grand Rounds lectures and CME programs to community-based physicians in multiple specialties to ensure state-of-the-art practice for primary care physicians. On a national level, the Division provides extensive update meetings drawing primary care physicians from around the country to review management issues for a wide range of pediatric ENT problems. In addition, members of the department give Instructional Courses each year at the American Academy of Otolaryngology Annual and at the American Academy of Pediatrics national meetings. In 1992, the Division created International Endoscopy Days at RCHSD, a world class meeting for pediatric otolaryngologists from around the world. The otolaryngologists participate in a day of live operative endoscopy followed by lectures, panels and open discussion on cutting-edge management of pediatric airway abnormalities. In April 2012 over 125 physicians from around the world attended the 15th International Endoscopy day at RCHSD. Four very challenging live airway endoscopy cases were performed by our group, observed by the attendees and spirited discussion, debate and audience interaction followed. Once again comments from the attendees such as “The best conference all yearernational Endoscopy day at RCHSD. Four The Cochlear Implant Program at RCHSD The Cochlear Implant (CI) team at RCHSD began in 2004 under the directorship of Daniela Carvalho, MD. This program has been critical in providing hearing restoration for children with profound hearing loss that do not benefit from hearing aids. This mode of hearing rehabilitation permits these children to enter into the mainstream community and achieve their full educational and communicative potential. Our multidisciplinary team includes hearing and speech specialists, an auditory verbal therapist, developmental psychologists and social workers from RCHSD. The program has grown steadily and there are more than 450 CI patients followed by our group and has been a dramatic success as shown by the growth and accomplishment of the team listed below. CI Tean Accomplishments/CI Growth • 2004: 10 CI surgeries year 2010: 52 CI surgeries/year FY2012: 30 CI surgeries/ year • 2007:238CI’sprogrammed/year2011: 420 CI’s programmed/year FY2012: 440 CI’s programmed • 2004:<100patients • 2011:>300patients • FY2012:>400patients Aural Rehabilitation Services/Providers • 2004:2SpeechLanguagepathologists • 2005:3SpeechLanguagepathologists • 2008:4SpeechLanguagepathologists • 2010:7SpeechLanguagepathologists • 2011:9SpeechLanguagepathologists, including auditory verbal therapist FY2012: 9 Speech Language pathologists, including auditory verbal therapist Audiology Services/Providers • 2004:1CochlearImplantaudiologist • 2005:3CochlearImplantaudiologists • 2009:4CochlearImplantaudiologists • 2011:5CochlearImplantaudiologists, one of whom is bilingual and one who has a cochlear implant • FY2012: 4 Cochlear Implant audiologists, one who has bilateral cochlear implants PRESENTATIONS/ RESEARCH • Poster–Unresponsiveness to bilateral cochlear implantation on an otherwise healthy deaf child. SENTAC 2005 • Poster–Possiblehormonal-inducedauditory symptoms in pediatric cochlear implant patients. ASPO 2007 • Poster–Howdoelectricalstapedialreflexes compare with neural response telemetry? International Pediatric Cochlear Implant Meeting 2007 • Poster–Comparisonofpediatriccochlear implant patients from a developed and a developing country. International Pediatric Cochlear Implant Meeting 2007 • Poster–Routine assessment indicates appropriate hearing aid benefit: Can we do better? International Pediatric Cochlear Implant Meeting 2008 • Poster–Bimodal-ism: Does frequency transposition technology have a role? International Pediatric Cochlear Implant Meeting 2009 • Poster–The fine line for indication of hearing aids versus cochlear implants: Can we do better? ASPO 2009 • Poster–Distortionsinpubescentcochlear implant patients: Real or phenomenon? AAA 2010 • NeedlemanA,RoseH.CochlearImplant Candidacy: What are the Determinants? Paper presented at the American Speech-Language-Hearing Association annual meeting. San Diego, CA, 2011 Pediatric Otolaryngology otolaryngology v5.indd 53 53 1/23/14 4:46 PM • IRB approval: Oral Language Capabilities of Monolingual and Bilingual Spanish and English Speaking Children with Cochlear Implants (Carvalho D. principal investigator), 2011 • Needleman A, Rose H. Candidacy Determinants for Pediatric Cochlear Implantation. Paper presented at the American Academy of Audiology annual AudiologyNOW! Conference. Boston, MA, 2012 • Rose H, Hu M, Mellish A. It Takes a Village. Paper presented at the Alexander Graham Bell Biennial Meeting. Denver, CO, 2012 • Carvalho D, Needleman A, Rose H. Pediatric Cochlear Implant Candidacy: What are the Best Evaluation Tools? Paper presented at the Society for Ear, Nose and Throat Advances in Children (SENTAC) Annual Meeting. Charleston, SC, 2012 • ListeningandSpokenLanguageTechniques: From Birth to High School. Full day conference put on by RCHSD focusing on listening and spoken language techniques for working with children with cochlear implants. San Diego, CA, 2013 Community/Family Outreach • Joyofsound • Parentworkshops 2009: 4 parent workshops 2010: 3 parent workshops • Teengroup • Spanishtoddlergroup • 2009: Cochlear implant team logo created • 2009: cochlear implant program brochure • 2010:Cochlearimplantvideocreated • 2012: Development of Audiologist & Speech Pathologist sessions for co-treating children who are not progressing as expected with their cochlear implants. The collaboration between speech pathologists and audiologists is resulting in more accurate program maps in the speech processors, leading to better functional hearing, and ultimately improved speech and language development • 2012: Trained the Cajon Valley early intervention, pre-school and elementary public school teachers of the deaf, 54 and speech pathologists, in the Auditory Verbal approach to intervention. • 2013:Music&LiteracyRoomcreated Community Education and Training • Speech Language Pathology Mentor Program: 3-4x/year • Educationalsitevisits,2x/year:Deafand hard of hearing center based programs - Lafayette Elementary - Whitman Elementary - Reidy Creek Elementary - Davila Day School - Magnolia Elementary • February2008:EducatorsWorkshop– Connecting care for children with cochlear implants: From the clinic to the classroom • 2009: RCHSD Workshop–Improving early identification of hearing loss • May 2011: El Centro Workshop– Cochlear implants and outcomes • August 2011: El Centro Outreach– Best practices in cochlear implants • 2012: Began parent education series that Heather Rose (AVT) presents monthly at the Ora Lingua School for children with hearing impairments Community Philanthropic Support • 2010: Auxiliary–Fuerte Hills Unit Sweet Charity Event: $36,395 to support comprehensive developmental evaluations, multidisciplinary case conferences, post implant therapies (AVT), and speech and language evaluations • June 2010: $500,000.00 gift pledge from Shirley and Sam Richter to support the Cochlear Implant Program AWARDS, HONORS AND MAJOR PRESENTATIONS Marcella Bothwell, MD • The International Women’s Leadership Association Woman of Outstanding Leadership Award 2013 • Rady School of Management Fellowship Award • NationalPractitionerExcellenceAward from Board of Governors American Academy of Otolaryngology 2011 • Consumer’sResearchCouncil,America’s Top Physicians 2009, 2010, 2011, 2012, and 2013 • Physician Development Award, Rady Children’s Foundation, 2010 National/Regional Society Activities • San Diego Academy of Otolaryngology HNS– Immediate Past President • California Otolaryngology Society– Board of Directors • AmericanAcademyofOtolaryngology– ENTPAC Board of Directors • Public Relations committee of the American Academy of Otolaryngology Head and Neck Surgery • AmericanAcademyofOtolaryngology/ Head and Neck Surgery (AAO.HNS) Millennium Society Life Member • RadySchoolofManagementWireless Health Club Chief Operating Officer 2013 – present Rady Childrens ENTPAC Committee • Pediatric Airway and Aerodigestive Team, Chair, RCHSD • IndicationsandTechniquesforPediatric Tracheostomy. Tracheostomy Day, RCHSD, San Diego, CA, August 2009 Television, Radio and Newspaper • Hearingloss/NoiseExposure,Women’s Health July, 2013 • Ear Wax is nature’s Defense against Objects and Infections, Union Tribune, May 15, 2012 • San Diego Union Tribune UTTV Internet Addiction Fact or Fiction? September 3, 2013 • San Diego Union Tribune UTTV Autism the Real Story August 27, 2013 • SanDiegoUnionTribuneUTTVVaccines Save Lives August 20, 2013 • SanDiegoUnionTribuneUTTVSummer Sunscreen Advice July 2, 2013 • San Diego Union Tribune UTTV Hearing 2013 June 25, 2013 • San Diego Union Tribune UTTV HPV Vaccine June 20,2013 • SanDiegoUnionTribuneUTTVKids Access to Marijuana, June 4, 2013 • SanDiegoUnionTribuneUTTVOral Cancer HPV Risks Parts One and Two, June 3, 2013 • San Diego Union Tribune UTTV Sports Fractures, April 9, 2013 • San Diego Union Tribune UTTV Scary Food Additives, March 5, 2013 • San Diego Union Tribune UTTV Pediatric Otolaryngology otolaryngology v5.indd 54 1/23/14 4:46 PM • • • • • • • • • • • • • • • • Women Versus Men in Sports, February 26, 2013 SanDiegoUnionTribuneUTTVProbing вЂ�Roid’ Rage, February 19, 2013 San Diego Union Tribune UTTV Obesity Myth February 5, 2013 San Diego Union Tribune UTTV Essence of Anti Oxidants January 29, 2013 San Diego Union Tribune UTTV Doctor weighs in on Lance Armstrong, January 17, 2013 SanDiegoChannel6,“Beforeandafter you have the flu” what are the best tips to getting better?, January 15, 2013 SanDiegoUnionTribuneUTTVDanger of Energy Drinks, January 8, 2013 SanDiegoUnionTribuneUTTVTruth About Blood Clots, January 1, 2013 San Diego Union Tribune UTTV Chronic Traumatic Encephalopathy in Football players December 4, 2012 SanDiegoUnionTribuneUTTV2012 Influenza Season, December 2, 2012 Dangerous Toys of Store Shelves Press Conference at Rady Childrens’ Hospital Multiple Local stations and Interview Channel 10, November 26, 2012 San Diego CW, Personal Music Players and Hearing Loss San Diego New 7 NBC, Personal Music Players and Hearing Loss ChokingandLocalChild’sDeath,San Diego NBC News, August, 2011 Choking and Children, San Diego KIUS News, February 22-23, 2010 Bucky Balls and Ingestion Risk, San Diego CW News, Spring 2011 Button Battery Ingestion Risk, San Diego Telemundo News, 2010 Daniela Carvalho, MD • • • • • America’sTopPhysicians2013 BestDoctorsinAmerica2009,2011 RCHSDBesttoListenToAward2009 SanDiegoSuperDoctors,2011 Second place, Clinical category, for the Poster: Survey of thyroglossal duct cyst in a subspecialty referral practice. 24th Annual ASPO (American Society of Pediatric Otolaryngology) Meeting, Seattle, WA, May 2009 • Third place for the poster “The Parental Perception Of Vestibular Impairments In Pediatric Cochlear Implant Patients”, SENTAC (Society for Ear, Nose and Throat Advances in Children) 39th Annual Meeting, Kansas City, MO, December, 2011 National/International Society Activities American Academy of Otolaryngology Head and Neck Surgery Implantable Hearing Aid Devices Committee, 2009-current American Society of Pediatric Otolaryngology Chairperson: Long Range/Strategic Planning Committee, 2012-2015 Society for Ear, Nose and Throat Advances in Children Member: Liaison Committee, 2009-2010; Chairperson, Liaison Committee, 2010-current • BrazilianAssociationofOtolaryngology, Head-Neck-Facial Surgery • Member, International Committee, 2009-2010 • Member, Educational Committee, 2009-2010 • International Working Group on Endoscopic Ear Surgery • Correspondingmember,2010 Rady Children’s Hospital-San Diego • Section Chief of Otolaryngology, 2009-current Rady Children’s Specialists of San Diego, A Medical Foundation • ContractsCommittee • PhysicianRetentionCommittee Community JCCNiermanPreschoolHealth&Safety Committee (2009-2010) Scientific Presentations Cellular Immunity in Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis (PFAPA) Syndrome. Broderick L, Page N, Carvalho D, Magit A, Jiang W, Simon L, Bothwell M, Kearns D, Pransky S, Hoffman H. The Federation of Clinical Immunology Societies, Boston, MA, June 2010 Pediatric caudal septal deviation and the Guillen suture technique: Does it provide better results? Pellman L, Carvalho D. Society of Ear, Nose and Throat Advances in Children 38th Annual Meeting, Cincinnati, OH, December 2010 Radiation exposure in pediatric cystic fibrosis patients with Chronic Sinonasal Disease: A 10-year review. Topp S, Donaldson C, Jiang W, Carvalho D. American Society of Pediatric Otolaryngology 26th Annual Meeting, Chicago, CA, May 2011 Hearing Loss in Newborns and Infants, Pediatric Update, Vol. 32, Moderator: Seth Pransky; Discussants: Daniela Carvalho and Natalie Loundon, March 1, 2012 Genetics Of PFAPA Syndrome, Broderick L, Carvalho D, Magit A, Jiang W, Leuin S, Bothwell M, Kearns D, Pransky S, Hoffman HM. 7th Congress of ISSAID (International Society of Systemic Auto-Inflammatory Diseases), Geneva, Switzerland, May 2013 Poster Presentations Cerebral magnetic resonance imaging and white matter changes in pediatric cochlear implant recipient. Society for Ear, Nose and Throat Advances in Children 37th Annual Meeting, Salt Lake City, UT, December 2009 Bilateral severe inner ear abnormalities in profoundly deaf non-twin siblings. Society for Ear, Nose and Throat Advances in Children 37th Annual Meeting, Salt Lake City, UT, December 2009 Distal renal tubular acidosis and sensorineural hearing loss: A case report. Society for Ear, Nose and Throat Advances in Children 37th Annual Meeting, Salt Lake City, UT, December 2009 Individualized treatment of lateral sinus thrombosis-Is mastoidectomy necessary? American Society of Pediatric Otolaryngology 25th Annual Meeting, Las Vegas, NV, May 2010 High-riding jugular bulb resulting in conductive hearing loss. Society for Ear, Nose and Throat Advances in Children 38th Annual Meeting, Cincinnati, OH, December, 2010 Invited Lectures International: Sinusitis en niГ±os: Cirugia endoscopica ВїSi o no? (Sinusitis in Children: Endoscopic surgery, yes or no?). XVI Congreso Estatal de Pediatria, XIX Pediatric Otolaryngology otolaryngology v5.indd 55 55 1/23/14 4:46 PM Jornadas Pediatricas del Colegio de Pediatras Capitulo Ensenada y Primer Encuentro Internacional de Pediatria, Ensenada, Mexico, June 27 2009 Atualização em otorinopediatria (Update on pediatric otolaryngology). International Grand Rounds of the Otolaryngology, Head and Neck Surgery department, UNICAMP (State University of Campinas), Campinas, Brazil, July 2, 2010 International Guest Faculty of the 40th Brazilian Congress of Otorhinolaryngology and Cervico-Facial Surgery, Natal, Brazil, November 23, 2010 - SГndrome de Down e otorrinolaringologia (Down Syndrome and otolaryngology) - SГndromes genГ©ticas em otorrinolaringologia (Genetic syndromes in otolaryngology) - Otologia pediГЎtrica (Pediatric otology) - AvanГ§os em estridor na infГўncia(Ad vances in stridor) International Guest Faculty of the I Pediatric Otolaryngology Meeting/ IV Pediatric Airway Meeting of the HCPA, Porto Alegre, RS, Brazil, June 24-26, 2011 - RuГdo respiratГіrio: DiagnГіstico diferencial (Differential diagnosis in upper respiratory sounds) - Hemangiomas em via aГ©rea (Airway hemangiomas) - Painel: Tratamento da surdez neurosensorial (Panel: Treatment of sensorineural), SГndromes genГ©ticas em otorrinolaringologia” (Genetic syndromes in otolaryngology - AvanГ§os em massas cervicais na infГўncia (Advances in pediatric neck masses) Imaging and Genetics in Auditory Neuropathy Spectrum Disorder: Is it just a wiring problem? San Diego Sound Wave Symposium, San Diego, CA, October 13, 2012 Update on Pediatric Hearing Loss, Practical Pediatrics, Escondido, CA, October 27, 2012 Lots of Snot and Cough: Is it a Sinus Infection? 15th Annual School Health Leadership Conference (AAP Chapter 3 CA), San Diego, CA, November 3, 2012 56 Management & Evaluation of a Child with Recurrent Croup, 2012 Ultimate Colorado Mid-Winter Meeting, Vail, CO, February 6, 2013 Hearing Loss in Children, Early Start Parent group meeting, Lafayette School, San Diego, CA, February 27, 2013 Television, Radio, Newspaper and Web Rady’s Celebrates Kids with Cochlear Implants, interview by Katie Orr, KPBS, June 15, 2009 Music for Her Ears, Kids News Day San Diego Union Tribune, October 20, 2009 Entrevista Dra. Carvalho, Ipod afecta jovenes (Interview with Dr. Carvalho: Ipod affects teenagers). Interview in Spanish for the TV channel Univision, August 23, 2010 Teens and hearing loss. Interview for Channel 6 San Diego, September 2, 2010 Aumentan casos de sordera en jГіvenes (Increase in the number of teenagers with hearing loss). DiГЎrio San Diego, September 9, 2010 “A crianГ§a ruidosa”(The noisy child), lecture given online for the Brazilian Academy of Otolaryngology (ABORLCCP) “Otoweb”, with live transmission to all Brazil, May 29, 2012 “Surge nueva condiciГіn mГ©dica conocida como вЂ�sordera del iPod’” (A new medical condition arises known as “iPod deafness”), interview for the program Primer Impacto, Channel Univision, September 5, 2012 “Rady Children’s Hospital Joy of Sound,” interview for the program Good Morning San Diego, TV Channel KUSI, June 20, 2013 Wen Jiang, MD • Physician Development Award, Rady Children’s Foundation, 2011 Rady Children’s Specialists of San Diego, A Medical Foundation • • • • ITCommittee–Member DivisionofPediatricOtolaryngology DirectorofThyroidDiseaseCenter Director of Speech Endoscopy Program • DirectorofIT • DirectorofInvitedLectureSeries Poster Presentations Is mastoidectomy necessary? Pellman L, Simon L, Jiang W, Carvalho D. Individualized treatment of lateral sinus thrombosis. American Society of Pediatric Otolaryngology 25th Annual Meeting, Las Vegas, NV, May 2010 Radiation exposure in pediatric cystic fibrosis patients with chronic sinonasal disease: a 10 year review. Topp SG, Donaldson C, Jiang W, Carvalho D. American Society of Pediatric Otolaryngology Annual meeting, Chicago, April 30, 2011 Temporary Tracheotomy for Removal of a Large Airway Foreign Body– When Bronchoscopy is not Enough. Nadaraja GS, Jiang W, Carvalho D. American Broncho-Esophagological Association’s 93rd Annual Meeting, Orlando, FL, April 10-11, 2013 Donald B. Kearns, MD Best Doctors in America 2009, 2010, 2011 San Diego Super Doctors, 2011 Super Doctors 2012, 2013 Founder’s Award Fresh Start Surgical Gifts, San Diego, CA 2011 U.S. News & World Report Top Doctor 2012-2013 Castle Connolly Top Doctors 2012-2013 Rady Children’s Hospital-San Diego • ChiefChiefMedicalOfficer • BoardofTrustees(ex-officio) Senior Vice president Health Affairs • Supply and Equipment Task Force, co-chairman • Co-Chairman, RCHSD Supply and Equipment Task Force 2011-current • SurgeoninChief Other Institutions • National Association of Children’s Hospitals and Related Institutions • Hospital De Las Californias Binational Committee • Organization of Children’s Hospitals Surgeons in Chiefs • MakeaWish,MedicalAdvisoryBoard University Committees University of California San Diego: Joint Risk Management Committee, Chairman Pediatric Otolaryngology otolaryngology v5.indd 56 1/23/14 4:46 PM Department of Surgery Credentials ad hoc Committee, Chairman Academic Advisory Committee Neonatology Search Committee, Chairman Skaggs School of Pharmacy Dean Search Committee Neonatology Chief Search Committee Pediatric Hepatology Search Committee Quality and Innovation Chief Search Committee Cardiac Surgery Search Committee Transplant Cardiology Search Committee Pediatric GI Chief Search Committee Surgeon in Chief Search Committee Department Of Surgery Chairman Search Committee Presentations Cellular immunity in periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome. Broderick L, Page N, Carvalho D, Magit A, JiangW, Simon L, Bothwell M, Kearns D, Pransky S, Hoffman H. The Federation of Clinical Immunology Societies, Boston, MA, June 2010 Medical Practice Foundation Update. UCSD Department of Surgery, La Jolla, CA, 2010 The Medical Practice Foundation: A new model for pediatric healthcare. Leadership Development Institute, RCHSD, San Diego, CA, 2010 Work environment and condition associated discomfort and injury. Cavanagh J, Hong P, Kearns D. Annual Resident Research Day, Dalhousie University, Halifax, Nova Scotia, Canada, April 2011 An ergonomics survey study of the American Society of Pediatric Otolaryngology Members. Cavanagh J, Hong P, Kearns D. Canadian Society of Otolaryngology, Victoria, British Columbia, Canada, May 2011 Work environment and condition associated discomfort and injury. Cavanagh J, Hong P, Kearns D. American Society of Pediatric Otolaryngology 26th Annual Meeting, Chicago, IL, May 2011 Discovery at RCHSD. Leadership Development Institute, RCHSD. San Diego, CA, 2011 Pediatric disaster surge training. San Diego County Healthcare Disaster Council, San Diego, CA, 2011 Business Domain Curriculum. UCSD Pediatric Hospital Medicine Fellowship Course, UCSD Department of Pediatrics, San Diego, CA, 2011 Immunoregulation at the Cellular Level in Periodic Fever, Aphthous Stomatitis, Pharyngitis Adenitis (PFAPA) Syndrome. Broderick L, Carvalho D, Magit A, Jiang W, Bothwell M, Kearns D, Pransky S, Hoffman H. Pediatric Translational Research Symposium, Rady Children’s Hospital, San Diego, CA, October, 2011 Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis (PFAPA) Syndrome: Evaluation of Patients. Broderick L, Magit A, Hoffman H, Carvalho D, Kearns D, Pransky S, Bothwell M, Jiang W. American Academy of Allergy, Asthma and Immunology, Orlando, FL, March, 2012 Evaluation of San Diego County Disaster Preparedness Best Practices. Hilfiker M, Abe C, Cox S, McDonough L, Rodriguez J, Kearns D. Trauma Center Association of America, Charleston, S.C., October 2012 Physician/Hospital Alignment in Pediatrics, Panelist for Webinar in Conjunction with ECG Management Consultants, 2012 Pediatric Airway Obstruction, Scripps Mercy Pediatric Grand Rounds, San Diego, CA, 2012 Stridor in Children, Scripps Mercy Pediatric Grand Rounds, San Diego, CA, 2012 Medical Practice Foundation Update. Leadership Development Institute. Rady Children’s Hospital and Health Center. San Diego, CA, 2012 Physician Hospital Relationships in Pediatrics. Children’s Hospital Association National Conference, Garden Grove, CA, March, 2013 Shelby Leuin, MD National Society Activities American Academy of Otolaryngology 10/2012-9/14 Member, Pediatric Otolaryngology Education Committee Posters Presentations Pediatric Salivary Gland Tumors. Lago D, Leuin SC, Pransky S. Poster presenta- tion at the Society of Ear, Nose, and Throat Advances in Children Annual Meeting Charleston, SC on November 30-December 2, 2012 Anosmia in the Pediatric Population. Lago D, Leuin SC, Pransky S. Poster presentation at the American Society of Pediatric Otolaryngology Annual Meeting San Diego, CA, April 20-22, 2012 Hoarseness as a Presenting Sign of Kawasaki Disease. Shanbhag S, Burns JC, Tremoulet AH, Sato YZ, Lago D, Leuin SC. Poster presentation at the 10th International Kawasaki Disease Symposium in Kyoto, Japan, February 7-10, 2012 Functional Rhinoplasty and Percutaneous Otoplasty. Poster presentation at the 2012 Annual Physician Meeting, Children’s Physicians Medical Group, San Diego, CA, May 10, 2012 Invited Lectures Pediatric Neck Masses. Presented at the Advances in the Practice of Pediatrics 27th Annual CME Conference in San Diego, CA, March 24, 2013 Pediatric Neck Masses. Presented at the Invited Speaker Conference at Rady Children’s Hospital, September 21, 2012 Pediatric Neck Masses: The good, the bad, and the ugly. Invited Lecture Pediatric Grand Rounds, Rady Children’s Hospital, August 24, 2012 Cleft Palate: An Otolaryngology Perspective. Presented at the Cleft Palate Care: A Team Approach Conference, San Diego, CA, March 3, 2012 Anthony Magit, MD • Best Doctors in America 2009, 2010, 2011, 2012, 2013 • Physician Development Award, Rady Children’s Foundation, 2010 • Received MPH from Johns Hopkins Bloomberg School of Public Health May, 2012. Master’s thesis: Basilar Skull Fractures in Infants and Children National/Regional Society Activities • President, Society of Ear, Nose and Throat Advances in Children • Co-Chairman, American Society of Pediatric Otolaryngology Ad Hoc Education Committee (2010) Pediatric Otolaryngology otolaryngology v5.indd 57 57 1/23/14 4:46 PM • American Society of Pediatric Otolaryngology: Member Vascular Malformations Task Force • AmericanAcademyofOtolaryngology-Head and Neck Surgery: Member Guideline Panel • American Academy of Otolaryngology-Head and Neck Surgery, Member Clinical Guideline Development Project Rady Children’s Hospital-San Diego • ImmediatepastChiefofStaff • MedicalStaffExecutiveBoard • Chairman, Credentials Committee (2010) • Chairman,InstitutionalReviewBoard • Co-Chairperson Quality, Safety and Medical Affairs Committee • Chairman,BylawsCommittee • Member,BoardofGovernorsMedical Practice Foundation • Member,VascularLesionsClinic Rady Children’s Specialists of San Diego, A Medical Foundation • Member, Clinical Research Advisory Committee • Vice-Chairman,AcademicAffairsand Research Committee University California San Diego • Member, UCSD Department of Surgery Research Advisory Committee • Member, UCSD Pediatric Human Subjects Protection Program • Co-director, UCSD medical school medical student mentor program • Member, UCSD pediatric Human Subjects Protection Program (IRB) committee • Mentor,UCSDHealthMentorsProgram San Diego County/Regional Service • Elected San Diego County Medical Society Board of Directors • Volunteer, San Diego City Schools Hearing Program • Volunteer,FreshStartSurgicalGifts State of California Service • Member, Board of Directors Children’s Specialty Care Coalition Scientific Presentations Chronic sinusitis in children. Instruc58 tional Course, American Academy of Otolaryngology-Head & Neck Surgery Annual Meeting, 2009, 2010, 2011, 2012 Stridor in infants and children. Instructional Course, American Academy of Otolaryngology-Head&NeckSurgery Annual Meeting, 2009, 2010, 2011 Invited lecture, Cystic Fibrosis Update. UC Davis Otolaryngology-Head & Neck Surgery Grand Rounds, Sacramento, CA, January 25, 2011 Poster Presentations Treatment of large lymphatic malformations of the head and neck in patients in early infancy. Society of Ear, Nose and Throat Advances in Children 37th Annual Meeting. Salt Lake City, UT, December 2009 Aspiration for management of large head and neck lymphatic malformations in early infancy. Society of Ear, Nose and Throat Advances in Children 37th Annual meeting. Salt Lake City, UT, December 2009 Invited lectures Panel Member, Management of Lymphatic Malformations American Society of Pediatric Otolaryngology 28th Annual Meeting. April 26, 2013 Alexandria, VA Seth Pransky, MD Best Doctors in America 2009, 2010, 2011, 2012, 2013 Best Doctors San Diego 2009, 2011, 2012, 2013 Castle Connolly Top Doctors 2012-2013 Ray Skoglund Excellence in Teaching Award RCHSD 2011 Chevalier Jackson Award, for Outstanding Achievement and accomplishment in Bronchoesophagology, from The American Broncho-Esophagological Association 2013 National/Regional Society Activities • Society of Ear, Nose and Throat Advances in Children, Member Program Committee for National Annual Meeting 2011 • Recurrent Respiratory Papillomatosis Task Force, Member, American Society Pediatric Otolaryngology Rady Children’s Hospital-San Diego • Director,SatelliteServices • RCHSDCMEDirectorPracticalPediatrics 2001-present • Member,MarketingCommittee • Member, Regional Task Force Committee • Member, Children Health Network Marketing Committee • Surgeon in Chief, Search Committee 2013• Network Governance Committee 2013• ServiceLineDevelopmentCommittee 2013Rady Children’s Specialists of San Diego, A Medical Foundation • Director, Pediatric Otolaryngology Department • Member,ExecutiveBoardofDirectors • Director,ClinicalPracticeCommittee • Director, Clinical Operations Committee • ViceChair,MarketingCommittee • PulmonaryDivisionPhysicianSearch committee 2012• SpacePlanningCommittee2013Scientific Presentations Simon LM, Tylor DA, Jiang W, Carvalho D, Bothwell MR, Kearns DB, Pransky SM, Magit AE. Survey of thyroglossal duct cyst in a subspecialty referral practice. 24th Annual American Society of Pediatric Otolaryngology Annual Meeting, Seattle, WA, May 2009 Intralesional cidofovir for the treatment of pediatric recurrent respiratory papillomatosis. American Society of Pediatric Otolaryngology. 24th Annual Meeting, Seattle, WA, May 22, 2009 Trying to understand PFAPA and its management: Preliminary results of a prospective clinicopathologic study. Society for Ear, Nose and Throat Advances in Children 37th Annual Meeting, Salt Lake City, UT December 6, 2009 Inferior Turbinate reduction using coblation in a pediatric population: A prospective clinical evaluation. American Society of Pediatric Otolaryngology 25th Annual Meeting, Las Vegas, NV, May 1, 2010 Pediatric Otolaryngology otolaryngology v5.indd 58 1/23/14 4:46 PM Prevalence of elevated IGE levels in a consecutive series of pediatric ENT patients. Society for Ear, Nose and Throat Advances in Children 38th Annual Meeting. Cincinnati, OH, Dec. 2, 2010 Poster Presentations Pediatric inferior turbinate reduction: Comparison of coblation and radiofrequency ablation techniques. American Society of Pediatric Otolaryngology 24th Annual Meeting, Seattle, WA, May 22, 2009 Button battery ingestion in the pediatric population. American Academy of Otolaryngology Annual Meeting, San Diego, CA, October 4-7, 2009 Management of ankyloglossia in infants with compromised feeding. Society for Ear, Nose and Throat Advances in Children 37th Annual Meeting, Salt Lake City, UT, December 3-6, 2009 Vocal cord paralysis in infants with tracheoesophageal fistulas. Society for Ear, Nose and Throat Advances in Children 38th Annual Meeting, Cincinnati, OH December 2, 2010 American Society of Pediatric Otolaryngology 27th Annual Meeting. Scientific Poster: Anosmia in the Pediatric Population, San Diego, CA, April 19-22, 2012 Invited Lectures International Visiting Professor, LIX Annual Mexican Congress of Otolaryngology. Veracruz, Mexico, July 22-25, 2009 - Rhinosinusitis in Children: Diagnosis and Management - The Draining Ear in Children - Round table: Management of Surgical Complications in Pediatric Otolaryngology - Human Papilloma Virus: Present and Future - Stridor in Infancy: Diagnosis and Management Invited Lecture, Human papilloma virus, present and future management issues. University of Montreal, Montreal, Canada, August 3, 2009 Invited Lecture, Otorrhea in children: Approach and management 2009. 3rd Annual McGill Auditory Sciences Laboratory Guest Lectureship, Montreal Children’s Hospital, Montreal, Canada, August 4, 2009 Invited Professor, X European Society of Pediatric Otolaryngology. Pamplona, Spain, June 5-8, 2010 Round table: Voice Disorders: Papillomatosis Invited Guest Professor, Department of Otolaryngology University Medical Center, Utrecht. Grand Rounds: Update of Otorrhea 2011. Utrecht, The Netherlands, March 15, 2011 Invited Lecture, Management of sinusitis in young children. Dialogues in Pediatric Otorhinolaryngology. Champery, Switzerland, June 26–29, 2011 Panel Instructor/Moderator, European Society of Pediatric Otolaryngology 11th International Congress. Handling the Patient Load in Different Societies. Amsterdam, Netherlands, May 20-23, 2012 Panel Chairman, European Society of Pediatric Otolaryngology 11th International Congress. Effective Teaching in Pediatric Otorhinolaryngology. Amsterdam, Netherlands, May 20-23, 2012 Guest Professor, LXIX Chilean Congress of Otorhinolaryngology, Concepcion, Chile November 7-10, 2012. Presentations: 1) Chronic Sinusitis in Children: Role of the Turbinates 2) Management of Nasal Obstruction of the Newborn 3) Update in Otitis Media 2012 4) Update in the Treatment of Subglottic Hemangiomas 2012 5) Alternatives in Management of Airway Endoscopy 6) State of the Art Treatment of Recurrent Respiratory Papillomatosis 2012 7) Round table: Glottic and Subglottic Stenosis in Children Guest Professor, Controversies in Pediatric Otolaryngology. Department of Otolaryngology Tel Aviv Sourasky Medical Center, Dana Children’s Hospital. January 18, 2013 1) Aerodigestive Tract Foreign Bodies: The New and the Old 2) Panel Moderator-presentation: The Legacy of Tympanostomy Tubes 3) Pediatric Airway Panel; Case Management Faculty, Invited Panel Lecturer, International Federation of Oto-Rhino-Laryngological Societies World Congress. Panel: Decision Making in the Treatment of Subglottic Stenosis in Children: Sharing the Airway with Anesthesia: Techniques for Subglottic Airway Abnormalities Seoul, Korea, June 3, 2013 National Director, International Endoscopy Days, San Diego, CA, 2009, 2012 Chronic sinusitis in children. Instructional Course American Academy of Otolaryngology-Head & Neck Surgery Annual Meeting, 2009, 2010, 2011, 2012 Stridor in infants and children. Instructional Course American Academy of Otolaryngology-Head&NeckSurgery Annual Meeting, 2009, 2010, 2011 Panel Moderator, Socioeconomic Panel: How to enhance your practice with clinical support. American Society of Pediatric Otolaryngology 24th Annual Meeting. Seattle, WA, May 22, 2009 Faculty, 34th National Primary Care Nurse Practitioner Symposium Copper Mountain, CO, July 16-19, 2009 Foreign Bodies of the Ear, Nose and Throat. Faculty, Ultimate Colorado Mid-Winter Meeting: An Otolaryngology Update. Finesse in pediatric bronchoesophagology for the general otolaryngologist. Vail, CO, Jan 24-28, 2010 Faculty, Western Section of Pediatric Otolaryngology (WESPO) Annual Meeting. Alternatives in endoscopic airway management. UCLA Medical Center Los Angeles, CA, March 13, 2010 Panel Member American Academy of Otolaryngology Annual Scientific Meeting Pediatric Otolaryngology Miniseminar: Adjuvant Therapy for Juvenile Recurrent Respiratory Papillomatosis. Boston, MA, Sept 26-29, 2010 Faculty, 67th Annual Brennemann Memorial Lectures; Los Angeles Pediatric Society, Anaheim, CA, October 7-10, 2010 - The Green Runny Nose-Is It Really Sinusitis - Hearing Loss in Infants and Newborns Pediatric Otolaryngology otolaryngology v5.indd 59 59 1/23/14 4:46 PM - Neck Masses-Differentiating Horses From Zebras - Round Table sessions: Stridor: Assessing the Airway from the Nose to the Lung Faculty, Pediatric Potpourri State of the Art 2011. AAP, California District IX, Chapter 2, Children’s Hospital Los Angeles Meeting, Maui, HI, February 12-18, 2011 - Neck Masses-Horses and Zebras - The Runny Nose-Chronic Sinusitis and Beyond - Foreign Bodies of the Aerodigestive Tract- What Must I Discuss with Parents - Update on Otorrhea-2011 - Update on Otitis media-2011 - Stridor: From the nose to the lung (Lunchtime Seminar, repeated three times) Panel Moderator, Pediatric Airway Nightmares. American Society of Pediatric Otolaryngology 26th Annual Meeting, Chicago. IL, April 29, 2011 Invited Lecture, Practical Pediatrics CME. Foreign Bodies of the Aerodigestive Tract-What Must I Discuss with Parents. San Diego, CA, May 14, 2011 Faculty, Massachusetts Eye and Ear Institute Update in Pediatric Airway, Voice and Swallowing Disorders. Recurrent Respiratory Papillomatosis and the Voice: Treating the Airway and the Voice. Boston, MA, May 21, 2011 Invited Lecture, Current State of Recurrent Respiratory Papillomatosis. Festschrift Honoring Robin Cotton, M.D. Boston, MA November 5, 2011 Panel Moderator, Society for Ear, Nose and Throat Advances in Children 39th Annual Meeting. The Legacy of the Cleft Palate Ear: Management Dilemmas. Kansas CityMO, Dec 1-4, 2011 Faculty, AAP Chapter 3 Advances in the Practice of Pediatrics. Presentation: Ankyloglossia and Nursing. San Diego, CA, March 23-25, 2012 Guest Professor, Fifth Annual New York City Airway Symposium. New York, NY October 11th, 2012. Presentations: 1) Medical and Surgical Approaches to the Young Child with Chronic Sinusitis 2) The Legacy of Tympanostomy Tubes-Sometimes It’s Not Just a Tube 60 Instructor, Pediatric Otolaryngology Fellow’s Webinar: Management of the Acute Airway. October 2012 Guest Professor, Billings Clinic Grand Rounds. Billings, Montana. February 22nd, 2013. Pediatric Neck Masses Guest Professor, Montana Society of Otolaryngology-Head and Neck Surgery Annual Meeting. Big Sky, Montana. Feb 23-24, 2013 1) Pediatric Stridor and Airway Management 2) Chronic Sinusitis in Children 3) Update of recurrent respiratory Papillomatosis 2013 4) Update on Otitis Media and Thoughts on Tympanostomy Tubes 2013 Panel Moderator, Robin Cotton Panel: My Worst Errors-Cases I Wish I Could Do Again American Society of Pediatric Otolaryngology 28th Annual Meeting. April 26, 2013 Alexandria, VA Guest Professor, New York University ENT Grand Rounds. Esophageal Foreign Bodies: The Old and the New. New York, NY, August 14, 2013 PUBLICATIONS Blakely E, Magit A. The role of tonsillectomy in reducing recurrent pharyngitis: A systematic review. Otolaryngology-Head and Neck Surgery, 140:291-297, 2009. Bothwell M. Twisted Trick. Science World, October 2009. Kearns D, Woods M, Summerside P. Redefining the physician executive. Physician Executive, 35(1):32-38, 2009. Neely G, Magit E, et al. A practical guide to understanding systematic reviews and meta-analyses. Otolaryngology-Head and Neck Surgery, 140:291-297, 2009. Smith M, Zimmerman M, Burke D, Magit A. et al. Efficacy and safety of OK-432 immunotherapy of lymphatic malformations. Laryngoscope, 119(1):107-15, 2009. Bothwell M. P3 Generation: Noise-induced hearing loss rising among children and adolescents. ENT Today, January 2010. Nely J, Magit A, Rich J, Voelker C, Wang E, Paniello R, Nussenbaum B, Bradley J. A practical guide to understanding systematic reviews and meta-analyses. Otolaryngol Head Neck Surg, 142(1):614, 2010. Hong P, Jurkowski Z, Carvalho D. Preoperative cerebral magnetic resonance imaging and white matter changes in pediatric cochlear implant recipients. Int J Pediatr Otorhinolaryngol, 74(6):658-60, 2010. Greenberg M, Carvalho D. Endoscopic adenoidectomy secondary to drug induced trismus. Scientific Research, 1(1):27-29, 2010. Hong P, Lago D, Seargeant J, Pellman L, Magit A, Pransky S. Defining ankyloglossia: A case series of anterior and posterior tongue ties. Int J Pediatr Otorhinolaryngol, 74(9):1003-1006, 2010. Wu A, Carvalho D. Congenital tympanic ring defect presenting as an external auditory canal mass. Ear, Nose and Throat Journal, 89(10):E44, 2010. Hilfiker M, Hulson J, Kearns D. Ergonomics and the physician executive. Physician Executive, 36(3):54-7, 2010. Page N, Kearns D. Labyrinthitis ossificans. Arch of Oto HNS, 137(3):303-305, 2011. Cole S, Kearns D, Magit A. Chronic esophageal foreign bodies and secondary mediastinitis in children. Annals of Otology, Rhinology & Laryngology Ann Otol Rhinol Laryngol. 120(8):542-5, 2011. Leuin SC, Shanbhag S, Lago D, Sato Y, Sun X, Jain S, Burns JC, Tremoulet AH. Hoarseness as a Presenting Sign in Children with Kawasaki Disease. Pediatr Infect Dis J, 2013 Jul 9. [Epub ahead of print] PMID 23811742. Leuin SC, Deschler D. The Missing Tracheo-Esophageal Puncture Prosthesis: Evaluation and Management. Ear Nose Throat J, 92(2): E14-16, 2013. Leuin SC, Chan KH, Upper Lip Dermoid in a 13-Month-Old Child. Otolaryngol Head Neck Surg, 147(2): 392, 2012. Cavanagh J, Brake M, Kearns D, Hong P. Work environment discomfort and injury: An ergonomic survey study of the American Society of Pediatric Otolaryngology members. Am J Otolaryngol, 33(4):441-6, 2012 Epub Dec 7, 2011. Broderick L, Carvalho D, Magit A, Jiang W, Bothwell M, Kearns D, Pransky S, Hoffman H. Periodic Fever, Aphthous Pediatric Otolaryngology otolaryngology v5.indd 60 1/23/14 4:46 PM Stomatitis, Pharyngitis, Adenitis (PFAPA) Syndreome: Evaluation of Patients in San Diego, CA. Journal of Allergy and Clinical Immunology, 129(2) Supplement AB214, 2012. Hong P, Bezuhly M, Taylor MS, Hart RD, Kearns DB, Corsten G. Tracheostomy versus Mandibular Distraction Osteogenesis in Canadian children with Pierre Robin Sequence: A Comparative Cost Analysis. J Otolaryngol Head Neck Surg, 1;41(3):207-14,2012. Hong P, Graham E, Belyea J, Taylor SM, Kearns DB. The Long-Term Effects of Mandibular Osteogenesis on Developing Deciduous Molar Teeth. Plastic Surgery International, Vol. 2012, Article ID 913807, 5 pages, 2012. doi:10.1155/2012/913807. Broderick L, Carvalho D, Magit A, Jiang W, Leuin S, Bothwell M, Kearns D, Pransky S, Hoffman H. Genetics of Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis (PFAPA) Syndrome. Journal of Allergy and Clinical Immunology, 131(2) Supplement AB159, 2013. Macdonald KI, Gipsman A, Magit A, Fandino M, Massoud E, Witterick IJ, Hong P. Endoscopic sinus surgery in patients with cystic fibrosis: a systematic review and meta-analysis of pulmonary function. Rhinology, 50(4). 360-9, 2012. Ambrosio A, Magit A. Respiratory distress of the newborn: congenital laryngeal atresia. Int J Pedatr Otorhinologol, 76(11): 1685-7, 2012. Hong P, McNeil M, Kearns DB, Magit AE. Mandibular distraction osteogenesis in children with Pierre Robin sequence: impact on health related quality of life. Int J Pedatir Otorhinolaryngol, 76(8):1159-63, 2012. Simon LM, Magit AE. Impact of incision and drainage of infected thyroglossal duct cyst on recurrence after Sistrunk procedure. Arch Otolaryngol Head Neck Surg, 138(1):20-4, 2012. Hong P, Brake MK, Cavanaugh JP, Bezuhly M, Magit AE. Feeding and mandibular distraction osteogenesis in children with Pierre Robin sequence: A case series of functional outcomes. Int J Pediatr Otorhinolaryn- gol, 76(3):414-8, 2012. Park E, Pransky S, Malicki D, Hong P. Unilateral Lymphangiomatous Polyp of the Palatine Tonsil in a Very Young Child: A Clinicopathologic Case Report. Case Reports in Pediatrics, Vol. 2011, Article ID 451542, 3 pages, 2011. Derkay C, Volsky P, Rosen C, Pransky S, McMurray JS, Chadha N, Froehlich P. Current Use of Intralesional Cidofovir of Recurrent Respiratory Papillomatosis. Laryngoscope, 000: 1-8. 2012. Jones TA, Jones S, Vijayakumar, S, Bothwell M. The adequate stimulus for mammalian linear vestibular evoked potentials (VsEPs). Jones TA, Jones SM, Vijayakumar S, Brugeaud A, Bothwell M, Chabbert C. Hear Res, 280(1-2):133-40, 2011. Books and Book Chapters Abe C, McDonough L, Cox S, Phalen D, Parker M, Hilfiker M, Schnell K, Kearns D. Pediatric Surge Planning. Train the Trainer. San Diego County Healthcare Disaster Council, San Diego, CA, 2011. Pransky S, Simon L. Clinical Evaluation of Stridor. Handbook of Pediatric Otolaryngology, Shapiro, NL Editor, World Scientific Publishing Co., Singapore, pp. 183-212. 2011. Magit A. Acute Upper Airway Obstruction. Textbook of Clinical Pediatrics. Second Edition, Elzouki, A Editor, Springer-Verlag, Berlin Heidelberg, 2012. Magit A. Congenital Anomalies of the Respiratory Tract. Textbook of Clinical Pediatrics, Second Edition, Elzouki, A Editor, Springer-Verlag, Berlin Heidelberg, 2012. Magit A. History and Physical Examination. Textbook of Clinical Pediatrics.Second Edition, Elzouki, A Editor, Springer-Verlag, Berlin Heidelberg, 2012. Pransky S, Tylor D. Neoplasms of the Larynx, Trachea and Bronchi. Pediatric Otolaryngology, Bluestone CD, Stool SE, Editors, Fifth Edition, BC Decker, Inc. Toronto, Canada (in press). Peterson MB, Pransky SM. Managing Recurrent Respiratory Papillomatosis and Care of the Voice. Pediatric Voice Disorders. Hartnick, CJ, Boseley, ME Editors, Pleural Publishing Inc., San Diego, CA. pp 191-204, 2012. Pransky SM, Francis CL. Stridor in Infants and Children. Pediatric Otolaryngology. Schoem, SR, Darrow, DH Editors, American Academy of Pediatrics, Chicago, Il. Chapter 15, pp 323-352, 2012. Leuin SC. Chronic Sinusitis. Chapter, Pediatric Otolaryngology Education Committee, American Academy of Otolaryngology Publications in Press Alyono J, Hong P, Nathan C, Bothwell M. Second branchial cleft anomaly with an ectopic tooth: A case report. ENT Journal. Mani N, McLeod, Jasmine, Sauder DN, Mani N, Haft M, Bothwell M. Novel use of Polymethylmethacrylate (PMMA) microspheres in the treatment of infraorbital rhytids. Journal of Cosmetic Dermatology, 32(8):749-59. Dutton P, Edmonds EW, Lark RK, Mubarak SJ: Prevalence of painful peroneal tubercles in the pediatric population. J Foot Ankle Surg, 51(5):599-603, 2012. Wenger DR, Hosalkar HS. Principles of treating the sequelae of Perthes disease. Orthop Clin North Am, 42(3):365-72, vii, 2011. Podeszwa DA, Mubarak SJ. Physeal fractures of the distal tibia and fibula (Salter-Harris Type I, II, III, and IV fractures). J Pediatr Orthop, 32 Suppl 1:S62-8, 2012. Edmonds EW, Roocroft JH, Mubarak SJ. Treatment of displaced pediatric supracondylar humerus fracture patterns requiring medial fixation: a reliable and safer cross-pinning technique. J Pediatr Orthop, 32(4):346-51, 2012. Gantsoudes GD, Roocroft JH, Mubarak SJ. Treatment of talocalcaneal coalitions. J Pediatr Orthop. 32(3):301-7, 2012. Chang RF, Mubarak SJ. Pathomechanics of Gowers’ sign: A video analysis of a spectrum of Gowers’ maneuvers. Clin Orthop Relat Res, 470(7):1987-91, 2012. Wenger DR. Limitations of evidence-based medicine: the role of experience and expert opinion.J Pediatr Orthop, 2012 Sep;32 Suppl 2:S187-92. Pediatric Otolaryngology otolaryngology v5.indd 61 61 1/23/14 4:46 PM Smith LR, Chambers HG, Subramaniam S, Lieber RL. Transcriptional abnormalities of hamstring muscle contractures in children with cerebral palsy. PLoS One, 2012;7(8):e40686. doi: 10.1371/journal.pone.0040686. Epub 2012 Aug 16. Chambers HG, Shea KG, Anderson AF, Jojo Brunelle TJ, Carey JL, Ganley TJ, Paterno M, Weiss JM, Sanders JO, Watters WC 3rd, Goldberg MJ, Keith MW, Turkelson CM, Wies JL, Raymond L, Boyer KM, Hitchcock K, Sluka P, Boone C, Patel N, American Academy of Orthopaedic Surgeons: American Academy of Orthopaedic Surgeons clinical practice guideline on: The diagnosis and treatment of osteochondritis dissecans. J Bone Joint Surg Am, 94(14):1322-4, 2012. Tis JE, Edmonds EW, Bastrom T, Chambers HG. Short-term results of arthroscopic treatment of osteochondritis dissecans in skeletally immature patients. J Pediatr Orthop. 32(3):22631, 2012. Chambers HG, Becker RE, Hoffman MT, Hartley-McAndrew M, Stein MT .Managing Behavior for a Child with Autism in a Body Cast. J Dev Behav Pediatr, 33:506-508, 2012. Smith LR, Chambers HG, Lieber RL. Reduced Satellite Cell Population May Lead to Contractures in Children with Cerebral Palsy. Dev Med Child Neurology, 2012. Gottschalk HP, Newbury R, Wallace CD. Synovial chondromatosis in a child’s thumb: a case report and review of the literature. Hand (NY), 7(1):98-102, 2012. Pring ME. Pediatric radial neck fractures: when and how to fix.J Pediatr Orthop, 32 Suppl 1:S14-21. 2012. Koenig JK, Pring ME, Dwek JR. MR evaluation of femoral neck version and tibial torsion. Pediatr Radiol, 42(1):113-5, 2012. Robertson NB, Roocroft JH, Edmonds EW. Childhood metatarsal shaft fractures: treatment outcomes and relative indications for surgical intervention. J Child Orthop, 6(2):125-9, 2012. Pandya NK, Edmonds EW. Immediate intramedullary flexible nailing of open pediatric tibial shaft fractures. J Pediatr 62 Orthop, 32(8):770-6, 2012. Bailey JR, Eisner EA, Edmonds EW. Unwitnessed magnet ingestion in a 5 year-old boy leading to bowel perforation after magnetic resonance imaging: case report of a rare but potentially detrimental complication. Patient Saf Surg, 19;6(1):16, 2012. Gottschalk HP, Sagoo D, Glaser D, Doan J, Edmonds EW, Schlechter J. Biomechanical analysis of pin placement for pediatric supracondylar humerus fractures: does starting point, pin size, and number matter? J Pediatr Orthop. 32(5):445-51, 2012. Wang E, Liu T, Li J, Edmonds EW, Zhao Q, Zhang L, Zhao X, Wang K. Does swaddling influence developmental dysplasia of the hip? An experimental study of the traditional straight-leg swaddling model in neonatal rats. J Bone Joint Surg Am, 94(12):1071-7, 2012. Edmonds EW. Use of an absorbable plate in the management of a clavicle fracture in an adolescent. Am J Orthop (Belle Mead NJ), 41(1):29-32, 2012. Eisner EA, Roocroft JH, Edmonds EW: Underestimation of labral pathology in adolescents with anterior shoulder instability. J Pediatr Orthop, 32(1):427, 2012. Register B, Pennock AT, Ho CP, Strickland CD, Lawand A, Philippon MJ. Prevalence of abnormal hip findings in asymptomatic participants: a prospective, blinded study. Am J Sports Med, 40(12):2720-4, 2012. Ellis HB, Matheny LM, Briggs KK, Pennock AT, Steadman JR. Outcomes and revision rate after bone-patellar tendon-bone allograft versus autograft anterior cruciate ligament reconstruction in patients aged 18 years or younger with closed physes. Arthroscopy, 28(12):1819-25, 2012. Wenger DR. Is there a role for acetabular dysplasia correction in an asymptomatic patient? J Pediatr Orthop, 2013 Jul-Aug; 33 Suppl 1: S8-S12. Vitale MG, Riedel MD, Glotzbecker MP, Matsumoto H, Roye DP, Akbarnia BA, Anderson RC, Brockmeyer DL, Emans JB, Erickson M, Flynn JM, Lenke LG, Lewis SJ, Luhmann SJ, McLeod LM, Newton PO, Nyquist AC, Richards BS, Shah SA, Skaggs DL, Smith JT, Sponseller PD, Sucato DJ, Zeller RD, Saiman L. Building consensus: development of a Best Practice Guideline (BPG) for surgical site infection (SSI) prevention in high-risk pediatric spine surgery. J Pediatr Orthop, 33 (5): 471-8, 2013. Smith LR, Chambers HG, Lieber RL. Reduced satellite cell population may lead to contractures in children with cerebral palsy. Dev Med Child Neurol, 2013 Mar; 55 (3): 264-70. Schulz JF, Chambers HG. Juvenile osteochondritis dissecans of the knee: current concepts in diagnosis and management. Instr Course Lect, 62: 455-67, 2013. Monazzam S, Bomar JD, Cidambi K, Kruk P, Hosalkar H. Lateral Center-edge Angle on Conventional Radiography and Computed Tomography. Clin Orthop Relat Res, 471(7):2233-7, 2013. Chambers HG. CORR Insights: Does Proximal Rectus Femoris Release Influence Kinematics In Patients With Cerebral Palsy and Stiff Knee Gait? Clin Orthop Relat Res, 2013 Jun 28. Chambers HG. Toxins for toe-walking: should they be used? J Bone Joint Surg Am, 95 (5): e31, 2013. Demura S, Yaszay B, Bastrom TP, Carreau J, Newton PO. Is decompensation preoperatively a risk in Lenke 1C curves? Spine (Phila Pa 1976), 38 (11): E649-55, 2013. Edmonds EW, Polousky J. A review of knowledge in osteochondritis dissecans: 123 years of minimal evolution from Konig to the ROCK study group. Clin Orthop Relat Res, 471 (4): 111826, 2013. Edmonds EW, Shea KG. Osteochondritis dissecans: editorial comment. Clin Orthop Relat Res, 471 (4): 1105-6, 2013. Edmonds EW, Templeton KJ. Childhood obesity and musculoskeletal problems: editorial comment. Clin Orthop Relat Res, 471 (4): 1191-2, 2013. Eisner EA, Roocroft JH, Moor MA, Edmonds EW. Partial rotator cuff tears in adolescents: factors affecting outcomes. J Pediatr Orthop, 33 (1): 2-7, 2013. Ejnisman L, Philippon MJ, Lertwanich P, Pennock AT, Herzog MM, Briggs KK, Pediatric Otolaryngology otolaryngology v5.indd 62 1/23/14 4:46 PM Ho CP. Relationship between femoral anteversion and findings in hips with femoroacetabular impingement. Orthopedics, 2013 March; 36 (3): e293-300. Fornari ED, Suszter M, Roocroft J, Bastrom T, Edmonds EW, Schlechter J. Childhood obesity as a risk factor for lateral condyle fractures over supracondylar humerus fractures. Clin Orthop Relat Res, 471 (4): 1193-8, 2013. Gargas J, Yaszay B, Kruk P, Bastrom T, Shellington D, Khanna S. An analysis of cervical spine magnetic resonance imaging findings after normal computed tomographic imaging findings in pediatric trauma patients: tenyear experience of a level I pediatric trauma center. J Trauma Acute Care Surg, 74 (4): 1102-7, 2013. Gottschalk HP, Bastrom TP, Edmonds EW. Reliability of internal oblique elbow radiographs for measuring displacement of medial epicondyle humerus fractures: a cadaveric study. J Pediatr Orthop, 33 (1): 26-31, 2013. Hosalkar HS, Pandya NK, Wenger DR. What’s new in pediatric orthopaedics. J Bone Joint Surg Am, 95 (4): 377-83, 2013. otolaryngology v5.indd 63 Ilgenfritz RM, Yaszay B, Bastrom TP, Newton PO. Lenke 1C and 5C spinal deformities fused selectively: 5-year outcomes of the uninstrumented compensatory curves. Spine (Phila Pa 1976), 38 (8): 650-8, 2013. Lark RK, Yaszay B, Bastrom TP, Newton PO. Adding thoracic fusion levels in Lenke 5 curves: Risks and benefits. Spine (Phila Pa 1976), 38 (2): 195-200, 2013. Millett PJ, Horan MP, Pennock AT, Rios D. Comprehensive Arthroscopic Management (CAM) procedure: clinical results of a joint-preserving arthroscopic treatment for young, active patients with advanced shoulder osteoarthritis. Arthroscopy, 29 (3): 440-8, 2013. Monazzam S, Bomar JD, Dwek JR, Hosalkar HS, Pennock AT. Development and prevalence of femoroacetabular impingement-associated morphology in a paediatric and adolescent population: a CT study of 225 patients. Bone Joint J, 95-B (5): 598-604, 2013. Newton PO, Marks MC, Bastrom TP, Betz R, Clements D, Lonner B, Crawford A, Shufflebarger H, O’Brien M, Yaszay B. Surgical treatment of Lenke 1 main thoracic idiopathic scoliosis: results of a prospective, multicenter study. Spine (Phila Pa 1976), 38 (4): 328-38, 2013. 1/27/14 10:57 AM Pathology The Pathology Division is responsible for all anatomic and clinical pathology diagnostic services and the educational programs in pediatric pathology for medical students, residents, and fellows. Additionally, the pathology staff contributes to and supports an array of activities including professional societies, public service agencies, and media productions. The pathologists are actively engaged in collaborative research occurring within the institution, at the University of California, San Diego (UC San Diego) School of Medicine, and with investigators from other institutions around the country. The pathologists are also intimately involved in the day-to-day administrative management of the laboratories. pathology v4.indd 64 1/23/14 4:45 PM FACULTY Robert O. Newbury, MD, Director, Clinical Professor of Pathology Henry F. Krous, MD, Director of Pathology Research, Clinical Professor of Pathology Eric Breisch, PhD, Associate Clinical Professor of Surgery Denise Malicki, MD, PhD, Clinical Professor of Pathology Katayoon Shayan, MD, Associate Clinical Professor of Pathology Linda Ellis, MD, Associate Clinical Professor of Pathology CLINICAL ACTIVITIES INPATIENT/OUTPATIENT POSTDOCTORAL FELLOWS AND RESIDENTS Shouying Du Don Xu Parham Minoo Nilesh Dharajiya Alison Carrigg Mariah Baughn Michele McElroy Mariana Canepa Karra Muller Boris Shlopov David Li John Nguyen Hyun Chung Nicole Saviano Patrick Sweet Rebecca Johnson Dorothy Wong Fang Wen Peter Kolbalka Jim Valentine Evelyn Potochny • • • The Pathology Division successfully maintained licensure by the State of California and Federal Drug Administration (FDA), is certified by CLIA, and maintained accreditations from the College of American Pathologists, American Association of Blood Banks, and the Joint Commission on Accreditation of Hospital Organizations (JCAHO). The pathologists serve as CAP inspectors of pathology departments at other children’s hospitals in the U.S. Annually, the clinical laboratory performs more than 1,500,000 tests, and transfuses over approximately 8700 blood products to approximately 2200 patients. LEFT TO RIGHT: Robert Newbury, Katayoon Shayan, Denise Malicki Pathology pathology v4.indd 65 65 1/27/14 10:58 AM • Diagnostic services include bacterial and fungal cultures, molecular diagnostic testing for infectious diseases, routine chemistry, sweat chloride testing, glucose tolerance testing, serology, urinalysis, hematology, selected coagulation studies, toxicology, and blood banking. • The Division uses polymerase chain reaction (PCR) to identify enteroviruses, HSV, CMV, and Bordatella pertussis, which serves not only Rady Children’s Hospital-San Diego (RCHSD), but other community hospitalsincludingNavalMedicalCenter San Diego, Paradise Valley, Sharp Memorial,UCSanDiego,Tri-City,Palomar/Pomerado,Alvarado,Grossmont, andNavalHospitalCampPendleton. • The Division also participates in the Drug Endangered Children (DEC) Forensic Pathology Program for detecting drug exposure in children. • TheDivisionprovideddiagnosticservices on approximately 55,000 separate surgical specimens from approximately13,000accessionedcases. • Greater than 100 new malignancies were identified annually. • The pathologists performed approximately 300 frozen section diagnoses from over 200 patients. • Approximately20postmortemexaminations are performed annually and the findings of many of them are presented at various medical staff conferences. • Electron microscopy was performed on approximately 200 specimens. • The Division continues to provide electronmicroscopyservicestoNaval Medical Center San Diego. • TheDivisionalsoprovidesrenalbiopsy consultations and interpretations and technical support to some hospitals in San Diego County. Eric Breisch, PhD Morphometry of infant cranium and dura Foreign body response to spinal implants RESEARCH ACTIVITIES The pathologists also teach UC San Diego surgical pathology fellows, residents, medical students and Naval Medical Center pathology residents who rotate through the department. Robert O. Newbury, MD Eosinophilicesophagitis Tuftingenteropathy Hart Isaacs, Jr., MD Neoplasiaofthefetusandearlychildhood 66 Henry F. Krous, MD Sudden infant death syndrome (SIDS) Sudden unexplained death in childhood (SUDC) Sudden death in infancy and childhood TEACHING ACTIVITIES The pathologists participate in numerous educational activities including conferences and lectures within and across departments and institutions. They are: • TumorBoard • Neuro-OncologyTumorBoard • NeuropathologyConference • OtolaryngologyConference • UropathologyConference • OrthopedicsConference • Gastrointestinal Pathology and Hepatic Pathology Conference • RenalPathologyConference • UC San Diego Pediatric Department CPCs • MorbidityandMortalityConferences • UCSanDiegoSOM208HumanDisease Course • UC San Diego SOM 213 Histology Course • UCSanDiegoSOMfirstyearproblem based learning curriculum • UC San Diego Clinical Laboratory Scientist program lectures • CMEcourseforDermatologicSurgeons • Superficial Anatomy and Surgery of theHeadandNeck • UCSanDiegoSOMmedicalstudents GrossAnatomy • Head and Neck Anatomy Course, Otolaryngology and Oral and Maxillofacial Surgery Residents • Surgery/Radiology/Pathology Conference • NeuromuscularPathologyConference AWARDS, HONORS AND MAJOR PRESENTATIONS Henry F. Krous, MD SIDS and Kids (Australia) Award, Baltimore, MD, October 5, 2012 Distinguished Researcher. International Society for the Prevention of Infant Death Achievement Award. Baltimore MD, October 7, 2012 California Sudden Infant Death Council Syndrome Advisory Council SIDS Lifetime Achievement Award. October30,2012,LosAngeles,CA The Soria Moria Conference Senior InvestigatorAward.Oslo,Norway,May 28, 2012 Star of the Decade Award, The SUDC Program.NewYork,NY,April14,2012 GuildforInfantSurvivalOrangeCounty (CA) Achievement Award, Santa Ana, CA, 2012 Rady Children’s Hospital Pediatric Pathology Lifetime Achievement Award, San Diego, CA, 2012 Sudden Unexpected Death in Children (SUDC):ANewEntity–SpecialRisk Profiles. Soria Moria Conference. SoriaMoria,Norway,May3,2012 Classification of Sudden Infant Deaths in Infants and Small Children. A Forensic Pediatric Pathologist’s View. Soria MoriaConference,SoriaMoria,Norway,May4,2012 Eric Breisch, PhD AAD Annual Meeting 2012 San DiegoAnatomy of the Head and Neck for Dermatologic Surgeons AAD Annual Meeting 2013 Miami- Anatomy of the Head and Neck for Dermatologic Surgeons Hugh Greenway’s Superficial Anatomy and Cutaneous Surgery Course 2012 and2013.Lectures:1.SuperficialAnatomy of the Head 2. Superificial AnatomyoftheNeck3.SuperficialFascia UCSD SOM Human Anatomy 2012. SuperficialAnatomyoftheHeadandNeck Robert O. Newbury, MD EosinophilicEsophagitis,anUpdate.UCSD School of Medicine, Pathology Research Lecture Series, December 5, 2011 Pathology pathology v4.indd 66 1/23/14 4:45 PM MAJOR GOALS & PLANS • • • • • pathology v4.indd 67 Provide anatomic and clinical pathology consultations and services to all of the clinical programs at RCHSD Continue to moderate and/or support medical staff educational, clinicopathologic, and quality assurance conferences Continue to serve as the pediatric pathology training experience for medical students, pathology residents, and surgical pathology fellows Continue to support extramural and community activities involving professional societies and governmental agencies Continue collaborative efforts with investigators, particularly in dermatology, gastroenterology, and hematology/oncology 1/27/14 10:15 AM What’s Under the Micropscope, EosinophilicEsophagitis,Gastroenteritisand Colitis.PresentedatEosConnection sponsored by American Partnership for Eosinophilic Disorders, San Diego, CA, July 7, 2012 Teen Discussion Group: Endoscopy- What happens while I am asleep? UndertheMicroscope.EosConnection sponsored by American Partnership for Eosinophilic Disorders, San Diego, CA, July 7, 2012 Denise Malicki, MD, PhD Pediatric Pathology Osler Pathology Board Review Course, Long Beach, CA,February26,2013 Hart Isaacs, Jr., MD Elected Fellow, Royal Society of Medicine, London, July 1, 2011 PUBLICATIONS Chambers H, Shea K, Carey J. AAOS Dohil R, Carrigg A, Newbury R. A Potential NewMethodtoEstimateTissueCystine ContentinNephropathicCystinosis.J Pediatr,161(3):531-535,2012. Du S, Scuderi R, Malicki DM, Willert J, Bastion J, Weidner N. Hodgkin and Non-Hodgkin lymphomas occurring in two brothers with Wiskott-Aldrich Syndrome (WAS) and review of the literature. Pediart Dev Pathol, 14(1):64-70,2011. Glaser D, Farnsworth CL, Varley ES, NunnTA,Sayad-ShahM,BreischEA, YaszayB.Negativepressuretherapyfor closed spine incisions: A pilot study. WOUNDS: A Compendium of Clinical Research and Practice.(inpress)2013. BroderickL,GandhiC,MuellerJL,PutnamCD,ShayanK,GiclasPC,Peterson KS, Aceves SS, Sheets RM, PetersonBM,NewburyRO,HoffmanHM, Bastian JF. Mutations of Complement Factor I and Potential Mechanisms of NeuroinflammationinAcuteHemorrhagic Leukoencephilitis. J Clin Immunol,33(1):162-71,2013. Gottschalk HP, Newbury R, Wallace CD. Synovial chrondromatosis in a child’s thumb: a case report and review of the literature. Hand(NY),7(1):98-102,2012. Inouye BM, Chiang G, Newbury RO, Holmes N. Adolescent xanthogranu68 lomatous pyelonephritis mimicking renal cell carcinoma on urine cytology: an atypical presentation. Urology, 81(4):885-7,2013. Dohil R, Newbury RO, Aceves S. Transient PPI Responsive Esophageal Eosinophilia May Be a Clinical Sub-phenotype of Pediatric Eosinophilic Esophagitis. Dig Dis Sci, 2012 May;57(5):1413-9. OtaniIM,AnilkumarAA,NewburyRO, BhagatM,BeppuLY,DohilR,Broide DH, Aceves SS. Anti-IL-5 therapy reducesmastcellandIL-9cellnumbers in pediatric patients with eosinophilic esophagitis. J Allergy Clin Immunol, 131(6):1576-82,2013. CrawfordJR,NewburyRO,FriedmanJR. An unusual presentation of posterior fossa ependymoma in a child. BMJ Case Rep,2013Jul5;2013 CrawfordJR,NewburyRO,LevyMLAn unusual posterior fossa tumour in a young child. BMJ Case Rep, 2013Jun 26,2013 Castle S, Suliman A, Shayan K, Kling K, Bickler S, Losasso B. Total colonic aganglionosis with skip lesions: report of a rare case and management. J Pediatr Surg,2012Mar;47(3):581-4 Broadbelt KG, Rivera KD, Paterson DS, Duncan JR, Trachtenberg FL, Paulo JA,StapelsMD,BorensteinNS,Belliveau RA, Haas EA, Stanley C, Krous HF, Steen H, Kinney HC. Brainstem deficiency of the 14-3-3 regulator of serotonin synthesis: a proteomics analysis in the sudden infant death syndrome. Mol Cell Proteomics, 2012 Jan;11(1):M111.009530. Randall B, Donelan K, Koponen M, Sens MA, Krous HF. Application of a classification system focusing on potential asphyxia for cases of sudden unexpected infant death. Forensic Sci Med Pathol,2012Mar;8(1):34-9. ByardRW,KrousHF,RognumTO.TheSoria Moria approach to pediatric forensic issues. Forensic Sci Med Pathol,2013. Carter CE, Shayan K, Mak RH, Yorgin PD, Krous HF. Nephrotic syndrome in an 18 year old boy with congential myelomeningocele: Questions. Pediatr Nephrol,Nov8,2012. Carter CE, Shayan K, Mak RH, Yorgin PD, Krous HF. Nephrotic syndrome in an 18 year old boy with congential myelomeningocele: Answers. Pediatr Nephrol, Nov7,2012. Krous HF. A commentary on changing infant death rates and a plea to use sudden infant death syndrome as a cause of death. Forensic Sci Med Pathol,9(1):91-3,2013. Trachtenberg FL, Haas EA, Kinney HC, Stanley C, Krous HF. Risk Factor Changes for Sudden Infant Death Syndrome After Initiation of Back to Back Sleep Campaign. Pediatrics,129 (4):630-8,2012. ClarkAB,StokesTA,KrousHF,Carbine DN.Myocardialinfarctioninanewborn heterozygous for the MTHFR C677Tmutation.Pediatr Dev Pathol, 15(3):232-6,2012. HolmIA,PoduriA,CrandallL,HaasE, GrafeMR,KinneyHC,KrousHF.Inheritance of febrile seizures in sudden unexplained death in toddlers. Pediatr Neurol, 46(4):235-92012. Yeh-NayreLA,MalickiDM,VinocurDN, Crawford JR. Medulloblastoma with excessive nodularity: radiographic findings and pathologic correlate. Case Rep Radiol, 2012:2012:310259. EpubOct12,2012. Crotty Alexander LE, Akong-Moore K, Feldstein S, Johansson P, Nguyen A, McEachernEK,NicatiaS,CowburnAS, OlsonJ,ChoJY,IsaacsHJr,JohnsonRS, BroideDH,NizetV.MyeloidcellHIF-1 alpha regulates asthma airway resistance and eosinophil function. J Mol Med (Berl),91(5):637-44,2013. BroadbeltKG,PatersonDS,BelliveauRA, Trachtenberg FL, Haas EA, Stanley C, Krous HF, Kinney HC. Decreased GABAAreceptorbindinginthemedullary serotonergic system in the sudden infant death syndrome. J Neuropathol Exp Neurol,Sep;70(9):799-810.,2011. ByardRW,MasoumiH,HaasE,SageM, Krous HF. Could intra-alveolar hemosiderin deposition in adults be used as a marker for previous asphyxial episodes in cases of autoerotic death? J Forensic Sci,May;56(3):627-9.2011. BOOKS Isaacs H. Tumors of the Infant and Fetus, AnAtlas,2ndEdition,Springer2013. Pathology pathology v4.indd 68 1/23/14 4:45 PM JOURNAL REVIEW Journal of Pediatric Surgery American Journal of Perinatology Obstetrics and Gynecology Pediatric Dermatology Journal of Pediatric Hematology and Oncology Ultrasound in Obstetrics and Gynecology Pathology-Research and Practice Acta Paediatrica World Journal of Pediatrics Indian Journal of Pathology and Microbiology Nigerian Journal of Surgery Pediatric and Developmental Pathology Forensic Science, Medicine and PathologyIllinois Child Welfare Pennock AT, Steadman JR. Outcomes and revision rate after bone-patellar tendon-bone allograft versus autograftanteriorcruciateligamentreconstruction in patients aged 18 years or younger with closed physes. Arthroscopy,2012Dec;28(12):1819-25. Wenger DR. Is there a role for acetabular dysplasia correction in an asymptomatic patient? J Pediatr Orthop, 2013 Jul-Aug;33Suppl1:S8-S12. Vitale MG, Riedel MD, Glotzbecker MP, Matsumoto H, Roye DP, Akbarnia BA, AndersonRC,BrockmeyerDL,Emans JB, Erickson M, Flynn JM, Lenke LG, Lewis SJ, Luhmann SJ, McLeod LM, NewtonPO,NyquistAC,RichardsBS., Shah SA, Skaggs DL, Smith JT, Sponseller PD, Sucato DJ, Zeller RD, Saiman L. Building consensus: development of a Best PracticeGuideline (BPG) forsurgical site infection (SSI) prevention in high-risk pediatric spine surgery. J Pediatr Orthop, 2013Jul-Aug;33(5):471-8. Smith LR, Chambers HG, Lieber RL. Reduced satellite cell population may lead to contractures in children with cerebral palsy. Dev Med Child Neurol, 2013Mar;55(3):264-70. SchulzJF,ChambersHG.Juvenileosteochondritis dissecans of the knee: current concepts in diagnosis and management. Instr Course Lect, 2013Feb; 62:455-67. Monazzam S, Bomar JD, Cidambi K, Kruk P, Hosalkar H. Lateral Center-edge Angle on Conventional Radiography andComputedTomography.Clin Orthop Relat Res,2013Jul;471(7):2233-7. Chambers HG. CORR Insights: Does Proximal Rectus Femoris Release Influence Kinematics In Patients With Cerebral Palsy and Stiff Knee Gait? Clin Orthop Relat Res,2013Jun28. Chambers HG. Toxins for toe-walking: should they be used? J Bone Joint Surg Am,2013March;95(5):e31. DemuraS,YaszayB,BastromTP,Carreau J,NewtonPO.Isdecompensationpreoperatively a risk in Lenke 1C curves? Spine(PhilaPa1976),2013May15;38 (11):E649-55. Edmonds EW, Polousky J. A review of knowledge in osteochondritis dissecans: 123 years of minimal evolution from Konig to the ROCK study group. Clin Orthop Relat Res, 2013Apr;471 (4):1118-26. Edmonds EW, Shea KG. Osteochondritis dissecans: editorial comment. Clin Orthop Relat Res, 2013 Apr; 471 (4): 1105-6. Edmonds EW, Templeton KJ. Childhood obesity and musculoskeletal problems: editorial comment. Clin Orthop Relat Res, 2013Apr;471(4):1191-2. Eisner EA, Roocroft JH, Moor MA, EdmondsEW.Partialrotatorcufftearsin adolescents: factors affecting outcomes. J Pediatr Orthop, 2013Jan;33(1):2-7. Ejnisman L, Philippon MJ, Lertwanich P, Pennock AT, Herzog MM, Briggs KK, Ho CP. Relationship between femoral anteversion and findings in hips with femoroacetabular impingement. Orthopedics, 2013March;36(3):e293-300. FornariED,SuszterM,RoocroftJ,Bastrom T, Edmonds EW, Schlechter J. Childhood obesity as a risk factor for lateral condyle fractures over supracondylar humerus fractures. Clin Orthop Relat Res,2013Apr;471(4):1193-8. Gargas J, Yaszay B, Kruk P, Bastrom T, Shellington D, Khanna S. An analysis of cervical spine magnetic resonance imaging findings after normal computed tomographic imaging findings in pediatric trauma patients: ten-year experience of a level I pediatric trauma center. J Trauma Acute Care Surg, 2013Apr;74(4):1102-7. GottschalkHP,BastromTP,EdmondsEW. Reliability of internal oblique elbow radiographs for measuring displacement of medial epicondyle humerus frac- tures: a cadaveric study. J Pediatr Orthop, 2013Jan;33(1):26-31. Hosalkar HS, Pandya NK, Wenger DR. What’s new in pediatric orthopaedics. J Bone Joint Surg Am,2013Feb;95(4): 377-83. Ilgenfritz RM, Yaszay B, Bastrom TP, Newton,PO.Lenke1Cand5Cspinal deformities fused selectively: 5-year outcomes of the uninstrumented compensatory curves. Spine (Phila Pa 1976),2013Apr15;38(8):650-8. LarkRK,YaszayB,BastromTP,Newton PO. Adding thoracic fusion levels in Lenke 5 curves: risks and benefits. Spine(PhilaPa1976),2013Jan15;38 (2):195-200. MillettPJ,HoranMP,PennockAT,Rios D. Comprehensive Arthroscopic Management (CAM) procedure: clinical results of a joint-preserving arthroscopic treatment for young, active patients with advanced shoulder osteoarthritis. Arthroscopy,2013March; 29(3):440-8. Monazzam S, Bomar JD, Dwek JR, HosalkarHS,PennockAT.Development and prevalence of femoroacetabular impingement-associated morphology in a paediatric and adolescent population:aCTstudyof225patients.Bone Joint J,2013May2;95-B(5):598-604. Newton PO, Marks MC, Bastrom TP, Betz R, Clements D, Lonner B, Crawford A, Shufflebarger H, O’Brien M, YaszayB.SurgicaltreatmentofLenke 1 main thoracic idiopathic scoliosis: results of a prospective, multicenter study. Spine(PhilaPa1976),2013Feb 15;38(4):328-38. Pathology pathology v4.indd 69 69 1/23/14 4:45 PM Surgery & Trauma The Division of Pediatric Surgery at Rady Children’s Specialists of San Diego (RCSSD) provides care to infants, children and adolescents with surgical diagnoses. These diagnoses include congenital anomalies, abdominal and thoracic surgical diseases, solid tumors, organ transplantation and trauma. The Division provides surgical operative care for approximately 3,000 patients a year. The Division provides hospital and office consultations and prenatal consultations for congenital disorders. All members of our board are certified in Pediatric and General Surgery. The Division of Pediatric Surgery continues to be a leader in minimally invasive procedures for children. Greater than ninetyeight percent of appendectomies are performed laparoscopically. Dr. Timothy J. Fairbanks, has continued to emphasize single site and minimally invasive procedures which result in essentially scarless operations. Advanced minimally invasive procedures are routinely performed in the chest and abdominal cavities on patients of all sizes. Difficult surgical procedures such as partial splenectomies, adrenalectomies and ovarian procedures can be performed with the benefits of less scarring, less pain and quicker return to full activities. Dr. Fairbanks has also helped organize the Division’s efforts to initiate a Pediatric Surgical fellowship training program. He is the Program Director for the training program. surgery and trauma v3.indd 70 1/23/14 4:43 PM Dr. Nicholas Saenz has special expertise and interest in Pediatric Surgical Oncology. He is a member of the Society of Surgical Oncology. He is the representative for the American College of Surgeons, and a member of the Emergency Medical Services for Children Trauma Advisory Committee for California. Dr. Karen Kling has been instrumental in designing, developing and implementing surgical applications for EPIC, the electronic health record at RCHSD. Dr. Stephen Bickler is an international expert in establishing pediatric surgical care in developing nations. He is a leader for the multi-center NIH grant supporting these efforts. Dr. Julia Grabowski joined the Division in September 2012. She is a skilled pediatric surgeon and is collaborating with Dr. Chiang on an EPIC based research projects regarding appendicitis & regarding ovarian cysts. She is the Assistant Training Program Director. Dr. Mary Hilfiker is the Trauma Medical Director & Division Director. RCHSD is the only American College of Surgeons nationally designated Level 1 pediatric trauma center in San Diego and Imperial counties. The hospital and division also receive injured children from the surrounding areas including Riverside County. The trauma center cares for over 1000 patients a year who have been designated as trauma patients. Since the inception of the trauma system sin San Diego in 1984, the trauma service at RCHSD has cared for approximately 30,000 children. The trauma service is nationally recognized for disaster preparedness and planning and is working with the CDC on disaster plans. FACULTY Stephen W. Bickler, MD, Clinical Professor of Surgery and Pediatrics, UCSD Timothy Fairbanks, MD, Assistant Professor of Surgery, UCSD Julia E. Grabowski, MD, Assistant Professor of Surgery, UCSD Mary L. Hilfiker, PhD, MD, MMM, Clinical Professor of Surgery, UCSD, Division Director, Trauma Medical Director Karen M. Kling, MD, Associate Professor of Surgery, UCSD Nicholas C. Saenz, MD, Clinical Professor of Surgery, UCSD Janelle De la Vina, NP LEFT TO RIGHT: Timothy Fairbanks, Julia Grabowski, Stephen Bickler, Karen Kling, Nicholas Saenz Surgery & Trauma surgery and trauma v3.indd 71 71 1/27/14 11:01 AM CLINICAL ACTIVITIES INPATIENT/OUTPATIENT Trauma The top three causes of serious injury to children seen in San Diego are falls, motor vehicle crashes and pedestrian versus motor vehicle injuries. In addition to clinical care, the trauma service members work to help families prevent injuries by sharing current trends via the RCHSD website, participating in media events and distributing educational materials such as one-page information sheets on a variety of injury prevention topics. Areas of special concern and focus for the past few years include of pedestrians struck by motor vehicles, drowning and children injured by falling televisions. The trauma center was re-certified by the American College of Surgeons as a Level 1 Pediatric Trauma Center in 2012. Pediatric Surgery The Division work closely with the oncologists in the care of children with cancer and with the neonatologists and perinatologists in the care of newborns with congenital anomalies. Division members are always available to provide immediate care for trauma patients and any urgent or emergent surgical problems. They are also involved in teaching the surgical residents, pediatric residents, medical students and nurses. We are actively involved in establishing an ACGME accredited pediatric surgery training program. In addition, general surgery residents from UCSD and The Naval Medical center are joining us to learn pediatric surgery & trauma. RESEARCH ACTIVITIES Dr. Bickler does research involving disease patterns in developed and developing countries. The Trauma Service conducts multiple epidemiologic studies and is actively involved in research projects with the Intensive Care and Emergency Medicine Fellows. These include research regarding the value of repeat imaging for head injuries, frequency of repeat imaging and use 72 of hypertonic saline in concussion and complications of hypertonic saline use. TEACHING ACTIVITIES The Division of Pediatric Surgery has initiated a Pediatric Surgery fellowship training program through the UCSD Graduate Medical Education office. This program has begun training our first fellow, Katherine P. Davenport, MD. The training program is in the process of obtaining ACGME approval and hopes to train one fellow per year. The process of becoming a Pediatric Surgeon is one of the most rigorous in all of medical training. We look forward to training future pediatric surgeons. The educational program within the Division of Pediatric Surgery has been enhanced over the last few years. General Surgery Residents from both the UCSD and Navy General Surgery departments rotate on service for a full year. There is a regular basic science conference weekly. The general surgery service has at least one case conference per week and occasionally more. Multidisciplinary conferences with specialties such as Neonatology, Pathology and Radiology now occur and allow organized communication about mutual patients. Dr. Nicholas Saenz is a site clerkship mentor for 3rd year medical students. All of the Surgery Division members participate in teaching residents and students from UCSD in addition to providing education for nursing and staff at RCHSD. All are members of RCSSD with faculty appointments at UCSD. All of the Surgery Division members are trauma surgeons also and involved in ongoing education and performance improvement. They also collaborate with adult trauma centers in San Diego and the County of San Diego Emergency Medical Services in these endeavors. Dr. Stephen Bickler is a consultant for the World Health Organization and travels internationally to teach and care for children with surgical disorders. AWARDS, HONORS AND MAJOR PRESENTATIONS Stephen W. Bickler, MD Kieswetter Lectureship, University of Pittsburgh Children’s Hospital, 2011 Oregon Health Science University, Department of Surgery, Alumnus of the Year, 2012 Invited Speaker Royal Australasian College of Surgeons, Melbourne 2012 Fulbright Scholarship, Mozambique, 2013 Invited Speaker International Surgical Society, Helsinki, Finland, August 2013 Election to American Surgical Association Nicholas C. Saenz, MD San Diego Magazine Top Doctor, 2009, 2010, 2011, 2012 Oncology Fellow Lecture Series, 2009 ALS graduate training Class, 2009, 2010, 2011 Best Doctor in San Diego, 2011, 2013 RN Residency Lectures 2009, 2010, 2011 EMS-C California Trauma Advisory Committee Karen M. Kling, MD American’s Top Surgeons 2008, 2010 Best Doctor’s in America 2009, 2010, 2011, 2013 Cares Award, 2011 Course Director Pediatric Surgery Sub-Internship 2007-present Champion–Pediatric Surgery block 2006-present (core medical school surgical clerkship) Champion–Pediatric Surgery resident education 2006-present Pediatric IBD Consortium 2009-present EPIC/Information Technology Committee 2008-present Pediatric IBD (inflammatory bowel disease) Consortium to address and evaluate potential avenues for investigation Abdominal Solid Organ Transplant Committee 2006-present Mary L. Hilfiker, MD Best Doctors 2010, 2011, 2012, 2013 Board of Directors, Trauma Center Association of America Board of Directors, ACS-PA, PAC Board Surgery & Trauma surgery and trauma v3.indd 72 1/23/14 4:44 PM Timothy J. Fairbanks, MD Top Docs San Diego Magazine 2012, 2013 Best Doctor 2013 Pediatric Surgery Fellowship Program Director 2012 - Current Penetrating Neck Trauma, San Diego Pediatric Emergency Medicine Regional Conference, February 14, 2013 Surgical Repair of Chest and Abdominal Abnormalities, Perinatal Diagnosis Conference 2013 PUBLICATIONS Gonda DD, Meltzer HS, Crawford JR, Hilfiker ML, Shellington DK, Peterson BM, Levy ML. Complications Associated With Prolonged Hypertonic Saline Therapy in Children With Elevated Intracranial Pressure. Pediatr Crit Care Med, 14(6):610-620, 2013. Bickler SW, De Maio A. Dysfunction of the innate immune system during sepsis: a call for research. Crit Care Med, 41(1): 364-365, 2013. Bickler SW, McQueen K. Proceedings of the 4th annual meeting of the Alliance for Surgery and Anesthesia Presence (ASAP): Building sustainable surgical systems. World J Surg, 37(7): 14601461, 2013. Bickler SW, Ring J, et al. Sulfur amino acid metabolism limits the growth of children living in environments of poor sanitation. Med Hypotheses, 77(3): 380-382, 2011. Castle S, Suliman A, Lossaso B, Bickler SW, Total colonic aganglionosis with skip lesions: report of a rare case and management. J Pediatr Surg, 47(3): 581-584, 2012. Cauvi DM, Song D, Vazquez DE, Hawisher D, Bermudez JA, Williams MR, Bickler S, Coimbra R, De Maio A. Period of irreversible therapeutic intervention during sepsis correlates with phase of innate immune dysfunction. J Biol Chem, 287(24): 19804-19815, 2012. Chang DC, Anderson JE, Kobayashi L, Coimbra R, Bicker SW. Projected lifetime risks and hospital care expenditure for traumatic injury. J Surg Res, 176(2): 567-570, 2012. Iddriss A, Shivute N, Bickler S, Cole-Ceesay R, Jargo B, Abdullah F, Cherian M. Emergency, anaesthetic and essential surgical capacity in the Gambia. Bull World Health Organ, 89(8): 565-572, 2011. Lazar DA, Cohen SA, Evora DK, Losasso BE, Bickler SW. Cecal bascule in a child: an unusual cause of postoperative bowel obstruction. J Pediatr Surg, 47(3): 609-611, 2012. Ramirez M, Chang DC, Bickler SW. Pediatric injury outcomes in racial/ethnic minorities in California: diversity may reduce disparity. JAMA Surg, 148(1): 76-80, 2013. Spiegel DA, Abdullah F, Price R, Gosselin R, Bickler SW. World health organization global initiative for emergency and essential surgical care: 2011 and beyond. World J Surg, 37(7): 14621469, 2013. Anderson JE, Lassiter R, Bickler SW, Talamini MA, Chang DC. Brief tool to measure risk-adjusted surgical outcomes in resource-limited hospitals. Arch Surg, 147(9):798-80, 2012. Anderson JE, Bickler SW, Chang DC, Talamini MA. Examining a common disease with unknown etiology: trends in epidemiology and surgical management of appendicitis in California, 1995-2009. World J Surg, 36(12):2787-94, 2012. Drummond R, Cauvi DM, Hawisher D, Song D, NiГ±o DF, Coimbra R, Bickler SW, De Maio A. Deletion of scavenger receptor A gene in mice resulted in protection from septic shock and modulation of TLR4 signaling in isolated peritoneal macrophages. Innate Immun, 19(1):30-41, 2013. Grabowski J, Vazquez DE, Costantini T, Cauvi DM, Charles W, Bickler SW, Talamini MA, Vega VL, Coimbra R, De Maio A. Tumor necrosis factor expression is ameliorated after exposure to an acidic environment. J Surg Res, 173(1):127-34, 2012. Montesa C, Fairbanks T, Kling K, Chang DC, Bickler SW. Evaluating Minimally Invasive Surgery from a Public Health Perspective. Southern California American College of Surgeons Program, abstract p 73, 2011. Castle S, Kling K, Bickler SW, LoSasso B. Long Segment Hirschprung Disease with Skip Lesions: Report of a Rare Case and Management. Southern California American College of Surgeons Program, abstract p 79, 2011. Chiang G, Fairbanks T, Initial use of LESS for the ACE Malone procedure in children. Urology, 80(3):717-8, 2012. Prasad R, Arthur LG, Timmapuri SJ, Schwartz MZ, Fairbanks TJ, Mendelson KG, Thatch K, Moront ML, Early experience with single-incision thoracoscopic surgery in the pediatric population. J Laparoendosc Adv Surg Tech A, 21(2):189-92, 2011. Books: Bickler SW, Ameh E (Eds). Surgical Care For Children: Guidelines For The Primary Referral Hospital. MacMillan Publishers. 2011. Ameh E, Bickler S, Lakhoo K, Nwomeh B, Poenaru D (Eds). Pediatric Surgery: A Comprehensive Text For Africa. Global Help, 2011. Surgery & Trauma surgery and trauma v3.indd 73 73 1/23/14 4:44 PM Pediatric Urology The Division of Pediatric Urology focuses on all aspects of genitourinary disorders encountered in children from birth through young adulthood. These varied conditions encompass treatment with both medical and surgical regimens. The Division has been honored since 2009 by being ranked in Pediatric Urology care by U.S. News & World Report’s “America’s Best Children’s Hospital.” Its most recent ranking in 2013 was #10 and continues to be the highest ranked program in the state of California; thus, reinforcing the world class care our patients are receiving at Rady Children’s Hospital-San Diego (RCHSD) in conjunction with Rady Children’s Specialists of San Diego (RCSSD). urology v4.indd 74 1/23/14 5:30 PM FACULTY NURSE PRACTITIONERS RESEARCH ACTIVITIES Nicholas M. Holmes, MD, MBA Chief, Division of Pediatric Urology, Clinical Professor of Surgery, UCSD George W. Kaplan, MD, MS, FAAP, FACS, Distinguished Clinical Professor of Surgery and Pediatrics, UCSD Madhu Alagiri, MD, Clinical Professor of Surgery, UCSD George Chiang, MD, Associate Clinical Professor of Surgery, UCSD Sarah Marietti, MD, Assistant Clinical Professor of Surgery, UCSD Ann Marie Berger Finley, MSN, FNP Queyn Nguyen, CPNP Dr. Chiang is leading the way for clinical research in our Division. As part of our commitment to investigating cutting edge therapeutics and improving the quality of care for our patients, we are actively involved in several clinical trials. By partnering with the biomedical industry, we are investigating novel forms of medications for children with neurogenic bladder. Two clinical trials involving new medical therapy to treat neurogenic detrusor overactivity in children performing intermittent catheterization were completed in 2013. He served as the principal Investigator in a study entitled, “A Multi-Center, Double-Blind, Place- FELLOWS Puneeta Ramachandra, MD, Fellow, Pediatric Urology (2011-2013) Gina Cambareri, MD, Fellow Pediatric Urology (2013-2015) CLINICAL ACTIVITIES INPATIENT/OUTPATIENT Over 9,000 patient visits per year were conducted in the Pediatric Urology Clinic in its main office on the campus of RCHSD and at its satellite clinics in Encinitas, Escondido, North County Coastal and Murrieta during 2011-2013. We have expanded our multi-disciplinary clinics besides the Spinal Defects Clinic which has been in existent for many years. In addition, we have created a Stone Clinic with our Nephrology colleagues which focus on the medical and surgical management of urinary stone disease. During the same time frame, over 3,000 surgical procedures per year were performed. LEFT TO RIGHT: Gina Camberreri, Madhu Alagiri, Tami Rechen, Sarah Marietti, Ann Marie Berger Finley, George Kaplan, Quyen Nguyen, Nicholas Holmes, George Chiang Pediatric Urology urology v4.indd 75 75 1/27/14 11:04 AM bo-Controlled, Dose-Titration Study Evaluating the Efficacy, Safety, Pharmacodynamics and Pharmacokinetics of Oxybutynin Chloride Topical Gel for the Treatment of Detrusor Overactivity Associated with a Neurological Condition in Pediatric.” Also, Dr. Chiang received UCSD Academic Senate Research Grant of $10,000 for basic science project involving the development of minimally invasive micturition animal model. He also received additional grant funding of $10,000 from RCSSD Physician’s Development Fund for research relating to strategic collaboration project for inquiry of pediatric electronic health information systems. Dr. Marietti in conjunction with Dr. Holmes are creating and designing a database to retrospectively and prospectively categorize patients who have vesicoureteral reflux. Specifically, they hope to address issues concerning surgical outcomes and quality indicators in the treatment of this disease. TEACHING ACTIVITIES The Division of Pediatric Urology continues our commitment to graduate medical education training with its ACGME accredited fellowship. Since its inception in 1985, Dr. George Kaplan has been and continues to act as program director. .. Dr. Puneeta Ramachandra has completed her fellowship in June 2013 and has joined the faculty at Children’s Hospital Central California. Dr. Gina Cambareri is our current clinical fellow who began the fellowship in July 2013. The Division of Urology participates in the following teaching activities: • UrologyresidentsfortheNavalMedical Center San Diego (NMCSD) and UCSD rotate on the service throughout the academic year • MonthlyClinicalCaseGrandRounds held jointly with NMCSD, UCSD and RCHSD • Biweekly Uroradiology conference with radiology, pediatric urology and pediatric nephrology faculty • Biweeklytutorialsessionsforresidents, fellows and faculty in pediatric urology 76 • Monthly Uropathology conference with pathology and pediatric urology faculty • Monthly journal club with review of the pediatric urology literature • Annual Grand Rounds held by the UCSD Division of Urology for the greater San Diego urologic community • Participation in the “Noon Lecture Series” for UCSD Department of Pediatric residents and trainees In addition, Drs. Holmes and Chiang have continued to support undergraduate and medical students via Dr. Holmes’ participation in the Health Professionals Mentor Program and Dr. Chiang’s participation in Project Nicaragua. AWARDS, HONORS AND MAJOR PRESENTATIONS Nicholas M. Holmes, MD, MBA Reviewer for the Journal of Urology, Section of Pediatric Urology Member, Quality Improvement Committee, RCHSD Member, Medical Staff Executive Committee, RCHSD Member, Kidney Transplant Committee, RCHSD Member, Surgery Executive Committee, RCHSD Member, Foundation Board of Trustees, RCHSD Member, Quality, Safety and Medical Affairs, Committee, RCHSD Member, Clinical Information Advisory Council, RCHSD Chair, Department of Surgery, RCHSD Chief, Section of Urology, RCHSD Medical Director, Clinical Documentation Improvement and ICD-10 Transition, RCHSD Medical Director, Surgical Services, RCHSD Chair, Joint Quality/Credentialing Committee RCSSD Member, Board of Governance Committee, RCSSD Member, Board of Directors, YMCAYouth and Family Services American Health Information Management Association (AHIMA) ICD-10 Summit Assuring a Solid ICD-10 Foundation through a Physician Engagement in Clinical Documentation, April 16, 2012, Baltimore, MD Pediatric Urology urology v4.indd 76 1/23/14 5:30 PM George W. Kaplan, MD, MS, FAAP, FACS Reviewer for the Journal of Urology, Pediatrics, and Journal of Pediatric Surgery Chair, Transplant Committee, RCHSD Examiner, American Board of Urology Selected for inclusion in Who’s Who in America (68th Edition) Honorable Mention in an article Who’s Who in Health and Medicine by J Bozanek, in News Digest International Health and Medical Merit Award from News Digest International, 2013 Included in Guide to America’s Top Surgeons, 2013 Included in Best Doctors in America, 2013 Listedin2011SanDiegoSuperDoctors 1st Place WSAUA History Essay: Peter Remondino-The Man, His Book and His Library, presented November, 2013 in Monterey, CA Faculty Presenter, Update on Bladder and Bowel Dysfunction, (BBD), and Education Special Interest Group. Pediatric Urology Nurse Specialists, American Academy of Pediatrics Annual Conference, New Orleans, LA,October12,2012 UCSD Pediatric Grand Rounds,Bladder and Bowel Dysfunction in Children, February 2013 Podium Presentation, Society of Urologic Nurses and Associates Annual Conference,Bladder and Bowel Dysfunction in the Pediatric Population, March 2013 American Urological Association, Pediatric Urology Nurse Specialists Annual Meeting, Chair of Special Interest Group Bowel Bladder Dysfunction Education May 2013 George Chiang, MD Member, Special Emphasis Panel for the CDC regarding funding for National Spina Bifida Registry Moderator and Presenter for Hispanic Educational Forum: Spina Bifida Association National Meeting Anaheim, CA, 2011 Member, Board of Director San Diego Spina Bifida Poster presentation, Bilateral Laparo-endoscopic Single Site Nephrectomy: a Pediatric Pretransplant Possibility, Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) Annual Meeting, San Antonio, TX 2011 UCSD Urology Faculty Educator Award, 2013 U.S. News & World Report, Top Doctors, 2013 Clinical Research Finalist, 2 Sessions of Behavioral Urotherapy. Society of Pediatric Urology World Congress Meeting, San Diego, CA, May 2013 Moderator, Spina Bifida: Urology PhysiologyandTreatment,SpanishLanguage LectureSeries38thSpinaBifidaAssociation Annual Meeting Anaheim, CA, June 2011 PUBLICATIONS Ann Marie Berger Finley, MSN, FNP Member-at-Large, Society of Urologic Nursing and Associates Catheterization task Force for Pediatric Protocol Development Sparks S, Kaplan A, Decambre M, Kaplan G, Holmes N. Eosinophilic cystitis in the pediatric population: a case series and review of the literature. Journal of Pediatric Urology, 2013 February 4. Bundenthal S, Belley S, Comfort A, Holmes N. et al. Guidelines for achieving a compliant query practice. Journal of AHIMA, 84 (2):50-53, 2013. Ramachandra P, Palazzi K, Skalsky A, Marietti S, Chiang G. Shunted hydrocephalus has a significant impact on quality of life in children with spina bifida. PM&R, May 22nd 2013, S19341482. Colangelo CJ, Kaplan GW, Holmes N, Palazzi-Churas K, and Chiang G. Ureteroscopy in Pediatric Patients with Spinal Abnormalities. J Endourology 2013 May; 27(5):545-8 Inouye, BM, Chiang G, Holmes N. Adolescent Xanthogranulomatous Pyelonephritis Mimicking Renal Cell Carcinoma on Urine Cytology: An Atypical Presentation. Urology, 81(4):885-7, 2013. Woo J, Sisul D, Kaplan G, Chiang G. Urologic outcomes of pediatric pelvic neuroblastoma presenting in acute urinary retention. Pediatric Hematology and Oncology, 2013 (in press). Woo J, Marietti S, Masterson J, Chiang G. Minimal incision laparoscopy assisted open pediatric pyeloplasty. Journal of Pediatric Urology, 2013 (in press). Kaplan GW. Urethral Strictures in Children. Curr Opin Urol, 22:462-466, 2012. Marietti S, Woldrich J, Durbin J, Sparks S, Kaplan G, Chiang G. Urologic findings on computed tomography of the abdomen and pelvis in a pediatric population. J Pediatr Urol, 2012 Jun 20. Alagiri M. Diagnosis and Management of Megaureter, Ectopic Ureter, Reflux, and Ureterocele. Urology Pearls of Wisdom, 4th Edition. Boston Medical Publishing Corp.Editor.DavidA.Levy.2012. Chiang G, Fairbanks T. Initial Use of LESS for the ACE Malone Procedure in Children. Urology, 2012 Mar 31. Sparks S, DeCambre M, Christman M, Kaplan G, Holmes N. Salvage ureteral re-implantation following failure of dextranomer/hyaluronic acid injection. Journal of Urology, 186: 257-260, 2011. Marietti S, Holmes N, Chiang G. Laparoendoscopic single-site (LESS) bilateral nephrectomy in pretransplant pediatric population. Pediatric Transplantation, 15 (4): 396-399, 2011. Woldrich J, Holmes N, Palazzi-Churas K, Alagiri M, Decambre M, Kaplan G, Chiang G. Comparison of laparoendoscopic single-site, conventional laparoscopy, and open nephrectomy in a pediatric population. Urology, 78(1): 74-77, 2011. Marietti S, Decambre M, Fairbank T, Kling K, Chiang G. Early experience with laparoendoscopicsingle-sitesurgery(LESS)inthe pediatric urology population. Journal of Endourology, 24 (8): 1321-1324, 2010. Chalmers D, Marietti S, Kim C. Xanthogranulomatous pyelonephritis in an adolescent. Urology, 76(6) 1472, 2010. Hackett L, Tarsa M, Wolfson T, Kaplan G, Vaux K, Pretorius D. Use of multi-planar 3-dimensional ultrasonography for prenatal sex identification. Journal of Ultrasound Medicine, 29:195-202, 2010. FLIP BOOK TO READ THE DEPARTMENT OF PEDIATRICS BIENNIAL REPORT Pediatric Urology urology v4.indd 77 77 1/23/14 5:30 PM BIENNIAL REPORT 2011-2013 DEPARTMENT OF PEDIATRICS DEPARTMENT OF CHILDREN’S SURGERY 1/23/14 1:30 PM Surgery cover v2.indd 3
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