1st MEETING

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SCIENTIFIC PROGRAMME
1 MEETING
st
NEW HORIZONS IN THE MEDICAL AND
SURGICAL TREATMENT OF BPH AND
PROSTATE CANCER
september 11-13, 2014
POLICLINICO TOR VERGATA FOUNDATION
ROME, ITALY
European Association of Urology
International Young Urological Association
Dear Colleagues and Friends,
We are delighted to invite you to participate in the 1st Meeting of ITRUST
(International Translational Research in Uro-Sciences Team), to be held in Rome, Italy, September 11-13, 2014.
ITRUST is an international group of “young” academic urologists interested in translational and clinical research
in all fields of urology.
The meeting is co-organized by the young urologists of the Departments of Urology of both the public universities
in Rome, the University of Tor Vergata and La Sapienza.
It would be a highly educational meeting, mainly directed to the young urologists, offering a wide scientific programme on the new
horizons in the treatments of prostate cancer and BPH.
All the young associations of urologists (EAU-Young Urologist Office; International Young Urological Association and the European Society
of Resident in Urology) have given us their active support. A very valuable international faculty will contribute to make the sessions highly
interesting and interactive.
The sessions will cover all the already established and the new medical and surgical treatments of prostate cancer and BPH, among which
the live surgery session will be extremely educational.
The ITRUST Award Session will give the young researchers the opportunity to present and discuss their last works and to win a very
special prize.
Knowledge exchange and networking between young urologists are the main objectives of the meeting.
We encourage you to join the meeting and, last but not least, visit Rome in an amazing season!
We look forward to seeing you the next September,
Roberto Miano
Cosimo De Nunzio
Policlinico Tor Vergata Foundation
University of Tor Vergata
S.Andrea Hospital
University La Sapienza
Rome, Italy
Rome, Italy
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MEETING OBJECTIVES
ITRUST (International Translational Research in Uro-Sciences Team) is a small group of young urologists interested
in translational and clinical research in different field of urology.
The purpose of this first meeting is to provide delegates with informations on the last clinical, pharmacological and surgical
treatment for prostate cancer and BPO due to BPH. Many questions remain still unanswered:
1) The traditional approach to localized prostate cancer with surgery or radiotherapy is now being in discussion due to the
significant complication rate. Emerging surgical techniques are now under clinical evaluation: focal therapy is a fact or fiction?
2) New drugs are now available for CRPC and metastatic prostate cancer: a multidisciplinary approach is advisable.
What the urologists need to learn from the oncologists?
3) Laser technology have gained great interest for BPO treatment
in the last years: is the TURP era really ended?
4) LUTS, inflammation, BPH, BPO, overactive bladder: what we
know and what we still need to know of this complex interaction?
THE LIVE-SURGERY SESSION WILL SHOW DELEGATES THE LAST TECHNOLOGIES FOR THE SURGICAL TREATMENT OF PROSTATE
CANCER AND BPH.
A SPECIAL ITRUST AWARDS POSTER SESSION WILL REFER THE VERY LAST CLINICAL AND TRANSLATIONAL RESEARCH OF
YOUNG UROLOGISTS IN THIS FIELD.
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1 MEETING
st
NEW HORIZONS IN THE MEDICAL
AND SURGICAL TREATMENT OF
BPH AND PROSTATE CANCER
september 11-13, 2014
POLICLINICO TOR VERGATA FOUNDATION, ROME, ITALY
DIRECTORS:
Roberto Miano, Cosimo De Nunzio
EXECUTIVE DIRECTOR OF ITRUST:
Fernando J Kim
HONORARY PRESIDENT:
Giuseppe Vespasiani
PRESIDENTIAL COMMITTEE:
Andrea Tubaro, Carlo De Dominicis,
Vincenzo Gentile
SCIENTIFIC COMMITTEE:
Anastasios Asimakopoulos, Pierluigi Bove,
Enrico Finazzi Agrò, Stefano Germani,
Costantino Leonardo, Alessandro Sciarra
CONFIRMED FACULTY:
Anastasios Asimakopoulos, Alfredo Berruti,
Pierluigi Bove, Maurizio Brausi, Fabio Calabrò,
Vittore Cereda, Luca Cindolo, Enrico Cortesi,
Sebastien Crouzet, Jean De La Rosette,
Cosimo De Nunzio, Bob Djavan, Mark Emberton,
Enrico Finazzi Agrò, Mauro Gacci, Richard Gaston,
Bogdan Geavlete, Stefano Germani, Gianluca Giannarini,
Paolo Gontero, Emre Huri, Christof Kastner,
Fernando J Kim, Pilar Laguna, Costantino Leonardo,
Paolo Marchetti, Roberto Miano, Salvatore Micali,
Vito Pansadoro, Giulio Patruno, Bernardo Rocco,
Mario Roselli, Alessandro Sciarra, Michiel Sedelaar,
Cesare Scoffone, Cora Sternberg, Andrea Tubaro
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SEPTEMBER 11, 2014
PROGRAM
10.00-12.00 Pre-Congress Courses
3-D LAPAROSCOPY: THE FUTURE OF RADICAL PROSTATECTOMY?
Directors: Pierluigi Bove - Salvatore Micali - Anastasios Asimakopoulos
CRYOTHERAPY FOR PROSTATE CANCER
Directors: Fernando J Kim - Roberto Miano
LASER FOR PROSTATE VAPORIZATION: PRINCIPLES AND TECHNIQUE
Director: Cosimo De Nunzio - Luca Cindolo
14.00 14.15 Registration
Welcome
Directors of the Meeting (Roberto Miano – Fernando J Kim - Cosimo De Nunzio)
Honorary President (Giuseppe Vespasiani)
Executive Director of ITRUST (Fernando J Kim)
General Manager of the Policlinico Tor Vergata (Tiziana Frittelli)
Director of the Department of Experimental Medicine and Surgery,
University of Tor Vergata (Gennaro Melino)
ESOU President (Maurizio Brausi)
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EAU-YOU President (Michiel Sedelaar)
IYUA President (Emre Huri)
Secretary General of SIU (Vincenzo Mirone)
Rector of the University of Tor Vergata (Giuseppe Novelli)
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15.00-15.20
Prostate Cancer Registries: the Italian experience (Andrea Tubaro)
SESSION: ADVANCED, METASTATIC AND CASTRATE - RESISTANT PROSTATE CANCER
Between hormonal manipulation, bone-targeted and chemotherapy
Moderators: Cora Sternberg - Maurizio Brausi
15.20-15.40 LH-RH agonist or antagonist? Continuos or intermittent therapy? (Alessandro Sciarra)
15.40-16.00 Abiraterone in post-ADT: biological modifications and clinical implications (Enrico Cortesi)
16.00-16.20 The actual role of chemotherapy in metastatic CRPC (Fabio Calabrò)
16.20-16.40 New radiopharmaceutical in mCRPC: Radium 223 dichloride (Paolo Marchetti)
15.20-18.00 16.40-17.00 Coffee Break
New horizons in therapeutic strategies for advanced, metastatic and castrate-resistant
prostate cancer
Moderators: Andrea Tubaro - Fabio Calabrò
17.00-17.20 Targeting the androgen receptor with Enzalutamide in mCRPC (Alfredo Berruti)
17.20-17.40 New insights on the combination of immunotherapy and chemotherapy
in metastatic CRPC (Mario Roselli - Vittore Cereda)
17.40-18.00 The future of therapeutic strategies for metastatic CRPC:
new drugs, new sequences or new combinations? (Cora Sternberg)
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PROGRAM
SEPTEMBER 12, 2014
LIVE SURGERY (EAU endorsed event) from the Policlinico Tor Vergata Foundation
Directors: Giuseppe Vespasiani - Fernando J Kim - Roberto Miano
Surgeons: Richard Gaston - Fernando J Kim - Andrea Tubaro - Bogdan Geavlete - Sebastien Crouzet - Christof Kastner
Moderators: Vito Pansadoro - Pilar Laguna - Mark Emberton - Bernardo Rocco
Provokers: Pierluigi Bove - Costantino Leonardo
Patient Advocate: Stefano Germani - Cosimo De Nunzio
Laparoscopic intrafascial radical prostatectomy
Focal cryoablation of prostate cancer
Vaporization of prostatic adenoma with Green Light XPS
Olympus Button TURis prostate vaporization
HIFU focal treatment for prostate cancer
MRI/TRUS fusion transperineal prostate biopsy
8.00-13.00 Lunch
14.00-17.00 SESSION: BPH
Medical treatment strategies: state of the art
Moderators: Enrico Finazzi Agrò, Alessandro Sciarra
14.00-14.20 Alpha-blockers and 5-ARI: alone or in combination? (Bob Djavan)
14.20-14.40 Antimuscarinics and beta-3-adrenergic agonist: when and how to treat the bladder in BPH patients?
(Enrico Finazzi Agrò)
14.40-15.00 Metabolic syndrome, inflammation, LUTS and BPH: which is the link? (Cosimo De Nunzio)
15.00-15.20 The role of PDE5 in the treatment of LUTS due to BPH (Mauro Gacci)
15.20-15.30 Discussion
Surgical treatment strategies: state of the art
Moderators: Jean De la Rosette, Luca Cindolo
13.30-14.00 7
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Face to face: Surgical treatment of big sized prostate adenoma
TURP
(Vito Pansadoro)
Laser enucleation
(Cesare Scoffone)
16.00-16.10
Discussion
16.10-16.40 Face to face: Surgical treatment of small-medium sized prostate adenoma
GreenLight Laser
(Andrea Tubaro)
TURis plasma vaporization
(Bogdan Geavlete)
16.40-16.50 Discussion
16.50-17.00 ESRU Lecture. Surgical training for BPH: results of an international survey
(Giulio Patruno)
17.00-18.00 ITRUST
Award session on BPH and Prostate Cancer
Moderators: Bob Djavan - Fernando J Kim
1. The Effect of Occupational Therapy on Well-being and Quality of Life of Patients
with Metastatic Prostate Cancer
(Meral Huri, Emre Huri, Hülya Kayıhan)
2. Is MP-MRI Alone Sufficient In Monitoring Prostate Cancer For Patients In Active Surveillance?
A. James, A.T. Gooneratne, A. Bhat, S. Muktar, A. Henderson
3. Plasma circulating miRNAs: a new potential biomarker for prostate cancer diagnosis
S. Giglio, C. De Nunzio, F. Presicce, R. Cirombella, A. Tubaro, A. Vecchione
4. Clinical Application of targeted stereotactic prostate biopsy: preliminary experience in our
Eugenio Martorana, Ahmed Ghaith, Riccardo Galli, Alessio Zordani, Maurizio Paterlini, Salvatore Micali,
Giampaolo Bianchi
5. Near Infrared Spectroscopy study of the bladder: a novel, non-invasive, diagnostic method of bladder outlet obstruction in men with lower urinary tract symptoms
Stefano Masciovecchio, Pietro Saldutto, Giuseppe Paradiso Galatioto, Carlo Vicentini
15.30-16.00 www.itrusturology.com
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PROGRAM
SEPTEMBER 13, 2014
SESSION: LOCALIZED PROSTATE CANCER
Moderators: Pierluigi Bove - Costantino Leonardo
09.00-09.20 IYUA Lecture. Periprostatic neural network in cadaveric fascial sparing radical prostatectomy (Emre Huri)
09.20-09.40
ESOU Lecture. Continence-sparing anatomical landmarks during radical
prostatectomy (Bernardo Rocco)
09.40-10.00
EAU-YUO Lecture. Hot issues in active surveillance for prostate cancer (Gianluca Giannarini)
09.00-12.30 10.00-10.20 Coffee break
TARGETED THERAPY FOR PROSTATE CANCER: FACT OR FICTION?
Moderators: Pilar Laguna - Fernando J Kim
12.20-12.30 Defining the ideal candidate for targeted therapy (Roberto Miano)
Transrectal or transperineal, 3-D or MRI-guided: evolving prostate biopsy in the
era of targeted therapy (Christof Kastner)
Why Cryoablation? (Fernando J Kim)
Focal treatment of prostate cancer with HIFU: principles and results (Sebastien Crouzet)
IRE - update from the CROES studies (Jean De la Rosette)
Vascular targeted photodynamic therapy (Paolo Gontero)
Targeted therapy: where do we stand and where are we going (Mark Emberton)
Discussion
12.30 Closure remarks
10.20-10.40 10.40-11.00 11.00-11.15 11.15-11.30 11.30-11.45 9
11.45-12.00 12.00-12.20 www.itrusturology.com
INFORMATION
FHOW TO REACH POLICLINICO TOR VERGATA (PTV)
The Policlinico Tor Vergata University Hospital is located in Viale Oxford 81, not far from several public transport
hubs and routes. They are, in fact, near the Metro A (Anagnina), the Rome-Pantano light rail and the GRA.
By car:
To get to the Policlinico coming from the GRA is advisable to use the outputs 17 (Tor Bella Monaca) and 20 (Romanina - Tor Vergata):
- Exit 17, the hotel can be reached by using about 4 km Viale Tor Bella Monaca, follow it to the intersection with Via Cambellotti,
(on the right see the steeple of the Church of Tor Bella Monaca) and follow the signs to the University Tor Vergata Policlinico Tor Vergata;
- Exit number 20, the Hospital can be reached by following the signs “Romanina - Tor Vergata” and later for the hospital.
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Coming from the A1 Rome-Naples can use the output of Torrenova (the first after the toll Rome South), take Via Passo Lombardo and follow
the signs to the University of Tor Vergata University and Hospital.
Public transport:
The lines 20 lim, 059 and 506, with terminal directly to the Policlinico Tor Vergata
20 The line deviates to the Policlinico Tor Vergata
The lines run from 20:20 lim Anagnina station (arrivals side Cotral-Metro)
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By plane:
From the international airport of Rome Fiumicino Leonardo da Vinci may serve the Leonardo Express train from the airport
that leads to Rome Termini station Fs. From there you can choose between different solutions:
- Use the Metro to Anagnina. From there take a bus lines available
- Make use of the line-Fs Rome Frosinone, stop at the station of Tor Vergata, from there use the free shuttle bus
From Ciampino airport you can reach by bus (every 20 ‘), the Ciampino Railway Station. From there go to Anagnina /Casal Morena and
take bus 506. Get off at Tor Vergata / Pisoni which is located a short distance from the hospital.
By bus:
Those arriving by bus at the interchange of Roma Tiburtina can reach the Policlinico Tor Vergata taking the Metro B to Tiburtina to Termini and
then the A from Termini to Anagnina. At that point, can choose one of the available lines
There are also two direct connections to the PTV departing from Ciampino and Frascati managed by Schiaffini Travel
By train:
For those arriving by train at Termini Station the easiest way to get to the Policlinico Tor Vergata is to use the Metro and go to Anagnina.
From there, use one of the available lines.
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Organizing Secretariat:
I.D.S. SpA
20, Via dell'Antracite - 00157 Rome, Italy
tel. +39 06 4505503 - 06 41792581
www.itrusturology.com
[email protected]
Provider ECM n. 3897:
Italymeeting s.r.l.
ECM n. 3897-94734