Bone Degeneration Therapeutics Market - Global Industry Insights 2024.pdf

Artificial Pancreas Market Industry
Bone Degeneration Therapeutics Market - Global
Industry Insights, Trends and Opportunity Analysis,
2016–2024
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Report Description
Bone Degeneration Therapeutics Market Overview
Bone Degeneration is characterized by deterioration of articular cartilage covering the joints. Cartilage
aids free movement of the joint without any resistance. Reduction in flexibility of the joint due to
deterioration of cartilage leads to inflammation, compressed nerves, and pain. Aging is one of the
natural causes of bone degeneration, which is also fueled by several conditions such as injuries,
congenital disorders, diabetes, and obesity. Symptoms of degenerative bone disorders includes joint
stiffness, radiating pain that initiates in the back and spreads through the extremities and causes joint
inflammation.
Osteoporosis – characterized by existence of porous bones may lead to fractures
There are two levels of bone loss that can result in an increased risk of fractures. Osteoporosis and
osteopenia constitute two levels of bone loss. Osteopenia is considered as loss of bone material density,
which indicates thinning of bones. Osteoporosis is a bone degeneration condition characterized by the
existence of porous bones and it develops with time as bones slowly lose minerals, structure, and
density, resulting in weaker bones. Eventually, osteoporosis leads to bent posture, cracked bones, and
loss of height.
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Excessive bone degeneration results in fragile bones that are highly susceptible to fracture. There are
several tests such as bone densitometers and dual energy x-ray absorptiometry scans performed to
determine the density of bones. Stimulation of soft tissues and cartilage repair with prolotherapy
represents some of the ways of alleviating pain resulting from degenerative bone disorders.
Increasing diabetes incidence and rising obesity driving growth of the bone degeneration
therapeutics market
Factors such as increased physical inactivity, rising obesity, and increasing rate of diabetes are fueling
growth of the bone degeneration therapeutics market. According to World Health Organization (WHO)
around 422 million people worldwide suffered from diabetes in 2014. Increasing number of diabetic
patients is fueling growth of the bone degeneration therapeutics market.
Various products in research pipeline to augment the bone degeneration therapeutics market
growth
Bone degeneration therapeutics market can be segmented by treatment and application. By treatment,
the bone degeneration therapeutics market can be segmented into device, drug, and surgery. Braces or
sleeves are used to relieve pain caused due to bone degeneration. These provide pain relief to
orthopedic patients. By drug, the bone degeneration therapeutics market is segmented into cortisone or
steroids, hyaluronic acid and platelet-rich plasma. Platelet-rich plasma is effective in alleviating pain
resulting from arthritis of the knee. Some products such as PREOB and ALLOB (both from Bone
Therapeutics SA) are in research pipeline. PREOB received orphan drug designation for osteonecrosis
in March 2008 from the U.S. FDA. On the basis of surgery, the bone degeneration therapeutics market
is classified as arthroscopy, high tibial osteotomy, and knee replacement. By application, the bone
degeneration therapeutics market can be segmented as osteoporosis, osteopenia, and spinal fusion.
Denosumab injection (Prolia) is used to treat osteoporosis in men, post-menopausal women, people
with increased risk for fractures, and those who cannot take or do not respond to other medications for
osteoporosis. It is also used to treat bone loss in men suffering from prostate cancer and women with
breast cancer.
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Increasing sports injuries and growing aging population drives growth of the bone degeneration
therapeutics market in North America
The market for bone degeneration has significant potential in North America due to high incidence of
sport injuries, availability of advanced technology, large aging population, robust medical infrastructure,
and favorable government reimbursement policy. According to 2016 estimates of Osteoporosis Canada,
over 80% of all fractures reported in people over 50 years of age are caused by osteoporosis and at
least one in three women and one in five men suffer from an osteoporotic fracture during their lifetime.
Asia Pacific is projected to be a high growth market for bone degeneration in the near future due to
increasing consumer health awareness and development of good diagnostic and treatment facilities in
the region.
Bone degeneration market: Key players
Amgen, Inc., Fate Therapeutics, Inc., Bone Therapeutics SA, Juventus Therapeutics, Inc., Kaken
Pharmaceutical Co., Ltd., Regenexx, and Se-cure Pharmaceuticals, Ltd. are some of the companies
involved in development of bone degeneration therapeutic products. Regenexx stem cell and plateletrich plasma procedures are advanced regenerative injection treatment used to treat knee pai n due to
arthritis, ligament injuries, and other degenerative conditions.
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Various products in research pipeline to augment the bone degeneration therapeutics market growth Bone degeneration therapeutics market can be segmented by treatment and application. By treatment, the bone degeneration therapeutics market can be segmented into device, drug, and surgery. Braces or sleeves are used to relieve pain caused due to bone degeneration. These provide pain relief to orthopedic patients. By drug, the bone degeneration therapeutics market is segmented into cortisone or steroids, hyaluronic acid and platelet-rich plasma. Platelet-rich plasma is effective in alleviating pain resulting from arthritis of the knee. Some products such as PREOB and ALLOB (both from Bone Therapeutics SA) are in research pipeline. PREOB received orphan drug designation for osteonecrosis in March 2008 from the U.S. FDA. On the basis of surgery, the bone degeneration therapeutics market is classified as arthroscopy, high tibial osteotomy, and knee replacement. By application, the bone degeneration therapeutics market can be segmented as osteoporosis, osteopenia, and spinal fusion. Denosumab injection (Prolia) is used to treat osteoporosis in men, post-menopausal women, people with increased risk for fractures, and those who cannot take or do not respond to other medications for osteoporosis. It is also used to treat bone loss in men suffering from prostate cancer and women with breast cancer.