Acute Heart Failure Therapeutics Market Clinical Review, Drug Descriptions, Analysis and Synthesis 2026

Acute Heart Failure (AHF)
Therapeutics Market
Global Market Analysis, Insights, Trends, and
Opportunity Inference, 2018-2026
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REPORT DESCRIPTION
Acute Heart Failure (AHF) Therapeutics Market Overview
Acute heart failure (AHF) is a progressive condition, in which, the heart muscle is unable to
pump enough blood through the heart to meet body’ optimal blood and oxygen level.
Congestive heart failure is type of heart failure which requires timely medical attention.
Moreover, distinguish between acute and chronic heart failure is important from a clinical
standpoint, on which further medication depends. For this, N terminal proB-type natriuretic
peptide levels are used for distinguishing acute versus chronic left ventricular dysfunction.
An elevated levels of natriuretic peptide were present in patients with acute heart failure
compared to those with chronic heart failure patient.
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Heart failure symptoms vary widely from person to person, depending on types of heart
failure patient. The main symptoms of heart failure are caused due to fluid accumulation or
congestion and poor blood flow to the body. Symptoms caused by fluid accumulation or
congestion includes shortness of breath, weight gain, coughing, swollen ankles, legs or
abdomen, while dizziness, rapid heart rate, and fatigue are symptoms associated with
reduced blood flow to parts of the body.
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REPORT DESCRIPTION
Acute Heart Failure (AHF) Therapeutics Market Drivers
The global acute heart failure therapeutics market is expected to witness significant growth
due to approval of new drugs. For instance, in July 2015, Novartis received U.S. Food and
Drug Administration (FDA) approval for their Entresto(TM) (sacubitril/valsartan) tablets on
the treatment of heart failure with reduced ejection fraction. Entresto is indicated to reduce
the risk of cardiovascular death and heart failure hospitalization.
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Furthermore, robust pipeline of drugs over the forecast period (2018-2026), is another
factor driving growth of acute heart failure therapeutics market. For instance, in March
2017, Cardioxyl Pharmaceuticals’ CXL-1427: a novel nitroxyl (HNO) donor (prodrug), which
now operates under the Bristol-Myers Squibb Company (after Cardioxyl Pharmaceuticals’
acquisition by Bristol-Myers Squibb in December 2015); is present in Phase 2 clinical
development phase. CXL-1427 is indicated to use as an intravenous treatment for acute
decompensated heart failure (ADHF). Successful completion and further launch of BristolMyers Squibb’s innovative drug in future, will help to boost the acute heart failure (AHF)
therapeutics market growth during the forecast period.
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REPORT DESCRIPTION
Some of the key players in this market are Novartis AG, Cardiorentis AG, Bristol-Myers
Squibb Company, Amgen Inc., Bayer AG, Cytokinetics, Inc., Merck & Company, Inc., Ono
Pharmaceutical Co., Ltd., and Pfizer Inc., among others. Key players in the marker are
engaged in development of new drugs for acute heart failure (AHF). These players are
incorporating collaboration strategies to remain competitive in the market.
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For instance, in October 2015, Cardiorentis AG announced plans to collaborate with Roche to
establish therapeutic efficacy and safety of Ularitide: Cardiorentis’ investigational drug for acute
heart failure (AHF). Under the terms of collaboration, Cardiorentis will incorporate Roche's
advanced in vitro diagnostic tests into its TRUE-AHF Phase III study to characterize the
pharmacological properties of Ularitide, evaluate its benefit-risk profile, and the appropriate
clinical application in patients.
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Acute heart failure (AHF) is a progressive condition, in which, the heart muscle is unable to pump enough blood through the heart to meet body’ optimal blood and oxygen level. Congestive heart failure is type of heart failure which requires timely medical attention. Moreover, distinguish between acute and chronic heart failure is important from a clinical standpoint, on which further medication depends. For this, N terminal proB-type natriuretic peptide levels are used for distinguishing acute versus chronic left ventricular dysfunction. An elevated levels of natriuretic peptide were present in patients with acute heart failure compared to those with chronic heart failure patient.