Myeloproliferative Neoplasms Treatment Market By Drug, Growth, Trends, And Analysis, 2018-2026

Myeloproliferative Neoplasms Treatment
Market GLOBAL INDUSTRY INSIGHTS, TRENDS, OUTLOOK,
AND OPPORTUNITY ANALYSIS, 2018-2026
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REPORT DESCRIPTION
Myeloproliferative Neoplasms Treatment Market – Overview
Myeloproliferative Neoplasms (MPNs) are a group of rare disease, in which the bone marrow produces excess
blood cells. It can be white blood cells, red blood cells or platelets. The overproduction of blood cells by the bone
marrow creates hindrance in the smooth flow of blood, which leads to various symptoms such as progressive
cytopenias, cachexia and weight loss, splenomegaly, and blastic transformation. These conditions are developed
gradually over a period of time. Most people are diagnosed after the age of 60 years, when they were accompanied
by many other health issues, makes the treatment more difficult. The major symptoms associated with MPNs
include bleeding problem, anemia, chest pain, fatigue, enlarged spleen, and weight loss. According to Annals of
Hematology, approximately 90% of patients has experienced MPN-symptoms in past 12 months, wherein women
are reported to have higher overall burden than men. The treatment for myeloproliferative neoplasms is mainly
aimed to reduce the excess number of blood cells circulation. The concept of myleoproliferative disease was first
given by hematologist Williom Dameshek in 1950. However, in 2008, World Health Organization (WHO)
classified hematologic malignancies and renamed myloproliferative diseases to myeloproliferative neoplasms.
Rising awareness of molecular abnormalities and cellular pathways involved in the pathogenesis of MPNs is
expected to facilitate the development of novel drugs, propels the Myeloproliferative Neoplasms treatment market
growth in the near future
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REPORT DESCRIPTION
Myeloproliferative Neoplasms Treatment Market Taxonomy:
Myeloproliferative neoplasm can significantly affect the quality of life of the patient. The
complication and treatments as well as the physiological strains of cancer diagnosis can affect
the physical and emotional wellbeing of patients. Effects of complication vary from depression,
fatigue, pain or depression with suicidal ideation. Moreover, patients can experience few or no
symptoms for a longer period of time. MPNs can be cured with proper monitoring and
treatment. There has been a major revolution in the management of MPNs by introduction of
JAK1 and JAK2 inhibitor and ruxolitinib. Ruxolitinib inhibits these two enzymes in order to
manage MPNs. The drug has also been proven as an alternative therapy for the treatment of
polycythemia vera. Further, the therapeutic armamentarium for MPN is still inadequate for
normalization of life span, reduction in cardiovascular complications, and prevention of
hematological progression.
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REPORT DESCRIPTION
Myeloproliferative Neoplasms Treatment Market: Key Players
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Collaboration among the biotech and pharmaceutical companies to identify new drugs for
MPNs is expected to accelerate the market growth
Novartis AG and Incyte Corporation are among the key players in Myeloproliferative
Neoplasms treatment market. According to MPN research foundation, biotech and
pharmaceutical companies are expected to propel the demand for improved treatments
and quickly connecting patients with latest treatment options. It is expected to lead
developing relationships with biotech and pharmaceuticals companies to identify new
areas for scientific exploration. For instance, Incyte Corporationis is developing inhibitor
for Janus Kinase (JAK) and also focusing on the discovery, development, and
commercialization of proprietary therapeutics globally.
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Rising awareness of molecular abnormalities and cellular pathways involved in the pathogenesis of MPNs is expected to facilitate the development of novel drugs, propels the Myeloproliferative Neoplasms treatment market growth in the near future