Lymphocyte Activation Gene - 3 Protein Market – Size, Growth, Outlook, and Analysis, 2018 - 2026

Lymphocyte Activation Gene - 3 Protein
Market GLOBAL INDUSTRY INSIGHTS, TRENDS, OUTLOOK,
AND OPPORTUNITY ANALYSIS, 2018-2026
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REPORT DESCRIPTION
Lymphocyte Activation Gene - 3 Protein Market – Overview
Immune checkpoint receptors such as lymphocyte activation gene - 3 (LAG-3) protein are found on cell
surface of effector T cells and regulatory T cells (Tregs). T cells are a type of white blood cells that
eliminate unhealthy or foreign cells that enter the immune system. Function of lymphocyte activation gene
- 3 protein is to control T cell response, activation, and growth. Lymphocyte activation gene - 3 turns off
the immune response when a T cell is activated to eliminate a target cell. This prevents the T cells from
harming healthy cells. Moreover, lymphocyte activation gene - 3 protein is associated with T cell
exhaustion in which the T cells become desensitized and lose their ability to function.
LAG-3 is closely associated with regulation of cytotoxic T cells and regulatory T cells, which has attracted
attention of researchers and manufacturers as a therapeutic target against cancer. In cancers, lymphocyte
activation gene - 3 expressing exhausted cytotoxic t cells and regulatory T cells (Tregs) are found to be
gathered at tumor locations. Recent studies reported that inhibiting LAG-3 functions allows T cells to
regain their cytotoxic function and affect tumor growth. There are several LAG-3 protein antibodies in the
clinical trials, which are expected to further advance in clinical trials over the forecast period.
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REPORT DESCRIPTION
Lymphocyte Activation Gene - 3 Protein Market Taxonomy:
By Drug Type:
●
BMS-986016 (Relatlimab)
●
IMP321
●
IMP701
●
MGD013
By Cancer Type:
●
Breast Cancer
●
Melanoma
●
Solid Tumors
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REPORT DESCRIPTION
Lymphocyte Activation Gene - 3 Protein Market: Key Players
●
Bristol-Myers Squibb.
●
Icell Kealex Therapeutics.
●
Incyte Corporation.
●
MacroGenics, Inc.
●
GlaxoSmithKline Plc.
●
Crescendo Biologics Ltd.
●
Regeneron Pharmaceuticals Inc.
●
Sutro Biopharma Inc.
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Recent studies reported that inhibiting LAG-3 functions allows T cells to regain their cytotoxic function and affect tumor growth.