Plasminogen Activator Inhibitor Market - Size, Share, Outlook, and Analysis 2018–2026

Plasminogen Activator Inhibitor Market GLOBAL INDUSTRY INSIGHTS, TRENDS, OUTLOOK, AND
OPPORTUNITY ANALYSIS, 2018-2026
REPORT DESCRIPTION
Plasminogen Activator Inhibitor Market – Overview
Plasminogen activator inhibitors also known as Serpin E1 is a protein present in the body whose elevated levels
are responsible for thrombosis and atherosclerosis. (Plasminogen Activator Inhibitor Type 1 (PAI-1) is mainly
secreted by the endothelium (cells lining blood vessels), and adipose tissues whereas Plasminogen Activator
Inhibitor Type 2 (PAI-2) is secreted by the placenta and only present in significant amounts during pregnancy.
PAI-1 plays an important role in aging and is secreted in senescent cells. Complete plasminogen activator
inhibitor 1 deficiency (complete PAI-1 deficiency) is a disorder that causes abnormal bleeding.
Increasing number of pipeline drugs for treating wounds and thrombosis can propel the growth of plasminogen
activator inhibitor market. For instance, Denver Health and Hospital Authority is undergoing clinical phase II
study for treating thromboembolism and wounds by aspirin and rosuvastatin. The study aims to measure PAI-1
and tissue plasminogen activator inhibitor levels in the plasma after drug treatment. The study started in February
2017 and is estimated to complete in December 2021.
REPORT DESCRIPTION
Plasminogen Activator Inhibitor Market Taxonomy:
By Product Type
Plasminogen Activator Inhibitor Type 1 (PAI-1)
Plasminogen Activator Inhibitor Type 2 (PAI-2)
By Application
Fibrinolysis
Cardiac Fibrosis
Post-operative Wound Hematomas
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REPORT DESCRIPTION
Plasminogen Activator Inhibitor Market – Key Players
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Bayer AG
SteadyMed Ltd
GlaxoSmithKline plc
Pfizer Inc., Abcam plc
ARUP Laboratories
Increasing product recall due to variations in the PAI kits is responsible for uneven results which is
affecting the growth of plasminogen activator inhibitor market. For instance, in July 2016, U.S. Food and
Drug Administration (USFDA) recalled IMUBIND Plasma PAI-1 Enzyme Linked Immunosorbant Assay
(ELISA) kits manufactured by American Diagnostica, Inc. The recall was initiated due to unacceptable
microwell to microwell variation in the section of the ELISA plates that is typically used for the calibrators.
This product affected the reproducibility of the results which can restrain the market.
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Increasing number of pipeline drugs for treating wounds and thrombosis can propel the growth of plasminogen activator inhibitor market