Immune Anti-Inhibitor Market - Global Industry, Analysis and Forecast till 2026

Immune Anti-Inhibitor Market GLOBAL INDUSTRY INSIGHTS, TRENDS, OUTLOOK, AND
OPPORTUNITY ANALYSIS, 2018-2026
REPORT DESCRIPTION
Immune Anti-Inhibitor Market – Overview
Researchers are working on analyzing the risks associated with use of replacement factors, as in which
replacement factors are more prone to facilitate development of antibodies. For instance, World Federation of
Haemophilia (WFH) announced results from study published in journal ‘Blood’ in 2014, which demonstrated
higher incidence of inhibitor development after treatment with Kogenate FS/Bayer/Helixate NexGen replacement
factor. The World Federation of Haemophilia has requested the U.S. Food & Drug Administration and the
European Medicine Agency (EMA) to examine the data. Such studies are expected to reduce the instances of
haemophilia with antibodies. Furthermore, therapies such as Immune Tolerance Induction (ITI) which involve
continuous treatment with replacement factors till they are no longer considered as foreign bodies by inhibitors
are expected to restrain the growth of the market.
Key players operating in global immune anti-inhibitor market include Shire Plc, Baxter International, Inc, F.
Hoffmann La Roche Ltd., Novo Nordisk A/S, and CSL Behring.
Immune inhibitors are associated with haemophilia and inhibitors are antibodies developed in haemophilia
patients. Haemophilia is a hereditary bleeding disorder, which occurs due to deficiency or absence of clotting
factor VIII (haemophilia A) or clotting factor IX (haemophilia B).
REPORT DESCRIPTION
Immune Anti-Inhibitor Market Taxonomy:
By Product TypeRecombinant
Plasma-Derived
Others
By Distribution ChannelHospital Pharmacies
Online Pharmacies
Retail Pharmacies
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REPORT DESCRIPTION
Immune Anti-Inhibitor Market – Key Players
Shire Plc
Baxter International
F. Hoffmann La Roche
Novo Nordisk A/S
CSL Behring
Although classification is not limited to the type of deficient clotting factor, it can be classified according
to amount of clotting factor present as well. For instance, depending on factor VIII levels in patients with
haemophilia A, it can be classified as mild haemophilia (5-25% of normal values), moderate haemophilia
(1-5% of normal values), and severe haemophilia (<1% of normal values).
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Immune system of haemophilia patients’ produces antibodies called as inhibitors, which acts against the administered therapy.