Myeloproliferative Neoplasms Treatment Market

Myeloproliferative Neoplasms Treatment
Market GLOBAL INDUSTRY INSIGHTS, TRENDS, OUTLOOK,
AND OPPORTUNITY ANALYSIS, 2018-2026
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REPORT DESCRIPTION
Myeloproliferative Neoplasms Treatment Market – Overview
Myeloproliferative Neoplasms (MPNs) are a group of rare disease, in which the bone marrow produces excess blood
cells. It can be white blood cells, red blood cells or platelets. The overproduction of blood cells by the bone marrow
creates hindrance in the smooth flow of blood, which leads to various symptoms such as progressive cytopenias,
cachexia and weight loss, splenomegaly, and blastic transformation. These conditions are developed gradually over a
period of time. Most people are diagnosed after the age of 60 years, when they were accompanied by many other health
issues, makes the treatment more difficult.
The major symptoms associated with MPNs include bleeding problem, anemia, chest pain, fatigue, enlarged spleen, and
weight loss. According to Annals of Hematology, approximately 90% of patients has experienced MPN-symptoms in
past 12 months, wherein women are reported to have higher overall burden than men. The treatment for
myeloproliferative neoplasms is mainly aimed to reduce the excess number of blood cells circulation. The concept of
myleoproliferative disease was first given by hematologist Williom Dameshek in 1950.
Myeloproliferative neoplasm can significantly affect the quality of life of the patient. The complication and treatments as
well as the physiological strains of cancer diagnosis can affect the physical and emotional wellbeing of patients. Effects
of complication vary from depression, fatigue, pain or depression with suicidal ideation. Moreover, patients can
experience few or no symptoms for a longer period of time.
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REPORT DESCRIPTION
Rising awareness of molecular abnormalities and cellular pathways involved in the
pathogenesis of MPNs is expected to facilitate the development of novel drugs, propels
the Myeloproliferative Neoplasms treatment market growth in the near future
Rising awareness of molecular abnormalities and cellular pathways involve in the pathogenesis of
MPNs is expected to facilitate the development of clinical trials with novel drugs, either alone or in
combination with ruxolitinib. Interferon (IFN) is a drug that has proven as an effective alternative for
MPNs patients. Better understanding of its mechanism of action for MPNs could lead to better
interferon compound and potential drugs.
In 2017, MPN research foundation have initiated a MPNRF Interferon (IFN) multi-center project
which is expected to bring together internationally recognized experts to determine cytokine-driven
pathways that affect the path of the MPNs. It is a closely-related group of progressive blood cancer
which is also among the lucrative opportunities for major players in the Myeloproliferative Neoplasms
treatment market.
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REPORT DESCRIPTION
Collaboration among the biotech and pharmaceutical companies to identify new
drugs for MPNs is expected to accelerate the market growth
Novartis AG and Incyte Corporation are among the key players in Myeloproliferative
Neoplasms treatment market. According to MPN research foundation, biotech and
pharmaceutical companies are expected to propel the demand for improved treatments and
quickly connecting patients with latest treatment options.
It is expected to lead developing relationships with biotech and pharmaceuticals companies to
identify new areas for scientific exploration. For instance, Incyte Corporationis is developing
inhibitor for Janus Kinase (JAK) and also focusing on the discovery, development, and
commercialization of proprietary therapeutics globally.
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Myeloproliferative Neoplasms (MPNs) are a group of rare disease, in which the bone marrow produces excess blood cells. It can be white blood cells, red blood cells or platelets. The overproduction of blood cells by the bone marrow creates hindrance in the smooth flow of blood, which leads to various symptoms such as progressive cytopenias, cachexia and weight loss, splenomegaly, and blastic transformation.