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Viroids and Prions - mvhs

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Viroids and Prions
Images taken without permission from http://www.newsandevents.utoronto.ca/images5/prions.jpg
Viroids
• Circular RNA molecules
• Infect plants
• Don’t code for proteins– disrupt regulatory
systems in plants
• Causes growth problems in plants
• Hepatitis D viroid causes Hepatitis D in
humans (in combination with virus)
Putative secondary structure of the PSTV (potato spindle tuber viroid).
Prions
• Infectious proteins
• Misfolded version of a naturally occurring
protein in animals
• Causes the similar proteins to also misfold
Unique pathogens
• Do not need to replicate themselves to
infect and cause problems
• Other infectious particles other than viruses
Prion Reproduction
• Prions cause other similar proteins to also
misfold lose function
Animations
• How Stuff Works Animation
• http://www.maxanim.com/microbiology/Pri
on/Prion.htm
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