todai tlo

“University-industry collaborations in Japan”
TODAI TLO, Ltd.
CEO & President ,Takafumi Yamamoto
http://www.casti.co.jp/
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
Niels Reimers : Father of Technology Licensing
In 1968 he established a research management office
and in 1969 the Office of Technology Licensing (OTL) at
Stanford University.
The successful launching of these two offices led to his
hiring by universities such as the Massachusetts Institute
of Technology (MIT), the University of California at Berkeley,
and the University of California at San Francisco, all of
which were seeking to establish their own offices
for technology transfers.
A cofounder of the Association of University Technology
Managers (AUTM), Reimers has served as chairman of
the Licensing Executive Society (U.S. and Canada) (LES).
Reimers now serves as a consultant, advising universities
around the world planning to open or operate their own
technology transfer offices.
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
University – Industry collaboration in US
AUTM Survey in 2008
・Number of invention disclosures
・Number of patent applications
・Number of licenses
・Number of New Products
・Number of Spin-offs
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
20,115
18,949
5,132
648
595
（19,827 in 2007）
（17,589 in 2007 ）
（5,109 in 2007 ）
（686 in 2007 ）
（555 in 2007 ）
Japanese Government encourages universities to do a
University-Industry collaborations.
The Basic Law for Science &Technology policy（1995）
The First Five year S&T Plan (1996～2000）
1998
Report on Innovation Research Group (MITI)
Law for Promoting Technology Transfer from Universities (TLO Law)
1999
Law for Special Measures for Industrial Revitalization
・Japanese Bayh-Dole Act
・Reduction of patent fees for approved TLOs
2000
Law to Strengthen Industrial Technology
・Allowing TLOs to use national university facilities free of charge
2001
1,000 University-start-ups in three years (Hiranuma Plan)
2004
Enforcement of National University Reformation Law
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
IPR Ownership
Incorporated as an Independent Agency
2004／April
National Universities had no legal status.
Universities could not be a patent owner.
National Universities get legal status.
Universities can be a patent owner.
IPR belonged to inventors
IPR belongs to Univ.
TLOs contracted with inventors
TLOs contract with Universities
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
Performance of university-industry
collaborations in Japan
2003
2004
2005
2006
2007
2008
Number of invention
disclosures
8078
8833
10202
10048
9438
9529
Number of patent
applications
(domestic)
1881
5085
7197
7282
6882
6980
Number of patent
applications
(overseas)
581
909
1330
1808
2987
2455
Number of patent
applications (total)
2462
5994
8527
9090
9869
9435
Number of licenses
－
－
1056
1128
1367
1319
Number of active
licenses
－
－
2731
3694
4820
3526
Royalty amount (10
thousand)
－
－
1.07 billion
1348.25
million
1207.1
million
1253.81
million
*The data shows the performance of about 70 member universities of the University Technology
Transfer Association without covering all performance.
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
Number of Inventions and filing Patents
（compare with US and Japan）
Invention
disclosures
発明開示／Ａ
ＵＴ/ AUTM
Ｍ
Patent
applications
AUTM
特許出願／Ａ
Ｕ/ Ｔ
Ｍ
Invention
disclosures / Japan
発明開示／日本
Patent
applications / Japan
特許出願／日本　18000
16000
14000
12000
63％
59％
10000
51％
8000
48％
6000
2000
0
27％
1991
28％
1992
29％
30％
1993
1994
32％
57％
34％
22％
1995
1996
1997
1998
1999
2000
2001
Number of Invention disclosures (US)
Number of Patent applications (US)
Number of Invention disclosures (Jpn)
Number of Patent applications (Jpn)

72％
51％
44％
40％
4000
51％
51％
AUTM Licensing Survey2005 and Mext Survey
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
2002
2003
2004
2005
University-industry collaborations SME in the US
Two thirds of technologies in US universities are licensed to smalland medium-sized companies and ventures, on the other hand,
few of those are licensed to small companies in Japan.
Licensees in the US
米国におけるライセンシー
Licensees
in Japan
日本のライセンシー
16.5％
2.4
33.5％
48.4
49.3
university-born
大学発ベン
ventures
チャー
Small
中小企業
companies
49.9％
Source: AUTM survey
startups
small companies
large companies
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
Large
companies
大手企業
*Source: AUTM survey 2004
Support Triangle for Industry-university
Cooperation at the University of Tokyo
University Corporate
Relations
University of Tokyo
Managing entity for IP:
Supports joint research through
the “Proprius21” scheme, etc.
TODAI TLO
Operating entity for IP:
Marketing licenses to
companies, etc.
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
University of Tokyo Edge
Capital (UTEC)
Supports the start-up of
university-oriented venture
businesses, in funds, human
resources, and other aspects.
Operations of Todai TLO
Researchers
 Invention
disclosure
University Corporate
Relations
⑥Determination of succession
 Interviews on
Patentability
Marketability
 Invention
disclosure
 Recommendation of
succession
Todai TLO
 Survey on patentability &
marketability
 Request for patent
application
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
 Licensing
Industry
Introduction of the organization and members of Todai TLO, Ltd.
President,
Yamamoto
Advisor, Mr. Adachi
1G (GM Ishida)
2G (GM Honda)
Liaison G
(GM Yamamoto)
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
Advisor, Mr. Ushio
Operation Support G
(GM Tenjin)
OA Team (GM Tenjin)
Number of Invention disclosure in 2005 (U.S. & Japan)
Name of university
Number of publication of
inventions
Number of domestic
applications
Application filing
rate
1,196
515
43.6%
University of Tokyo
627
313
49.9%
California Institute of Technology
549
416
75.8%
Tohoku University
527
380
72.1%
Osaka University
525
261
49.7%
MIT
515
287
55.7%
Tokyo Institute of Technology
464
317
68.3%
Kyoto University
457
324
70.9%
University of Wisconsin
405
163
40.3%
University of Pennsylvania
392
536
136.7%
University of California System
*Source: AUTM U.S. Licensing Survey FY 2004 for the US data and the “Performance of university-industry
collaborations FY 2005” of the Ministry of Education, Culture, Sports, Science and Technology for Japanese
data.
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
TODAI-TLO performance
(Jan-Dec)
The number of invention disclosures that TODAI TLO accepted
東京大学TLOにおける発明届出数の推移
800
684
700
629
600
589
657
648
2009
2010
615
500
400
300
247
200
100
0
2004
2005
2006
2007
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
2008
Number of patent applications
東京大学TLOにおける出願件数の推移
900
Domestic application
国内出願
800
外国出願
Overseas application
700
431
600
500
421
400
431
402
320
350
354
300
298
200
172
100
0
56
21
69
11
90
42
1998 1999 2000
107
52
88
55
2001 2002
105
66
226
97
95
2003 2004 2005
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
238
426
2006 2007
2008 2009 2010
Number of Agreements
東京大学TLOにおける契約件数の推移
350
300
250
その他
Others
大学共同出願
Joint patent agreements
大学ライセンス
Licensing (IPR belong to Univ)
個人ライセンス
Licensing (IPR belong to inventors)
200
25
21
22
17
192
176
116
176
177
31
13
50
49
8
5
24
2000
2001
2002
3
0
23
199
150
100
27
21
31
42
42
2003
3
2004
38
31
2005
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
69
64
11
45
6
2006
2007
2008
5
49
1
2009
79
2010
Royalty incomes
東京大学TLOにおける技術移転収入金の推移
10 thousands Japanese Yen
50,000
45,000
40,000
35,000
Royalty Incomes IP belong to inventor
個人帰属
Royalty Incomes from Joint Patent
大学帰属(共願)
Royalty Incomes IP belong to Univ.
大学帰属
Others
その他
収入金合計：39億6,604万円(累計)
30,000
248,300
25,000
1,381
1,164
20,000
2,155
1,692
7,642
15,000
6,636
1,927
1,024 13,489
1,178 344 2,186
17,673
1,923
10,000
12,274
5,808
6,755 7,724 5,566
7,780
100
170
5,000
4,574
3,154 4,947 5,111 4,337 2,508 3,701 2,833 3,423 3,846
1,930
1,349
0
2000
2001
2002
2003 2004
2005
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
2006 2007
2008
2009
2010
PeptiDream Inc.
Innovative Peptide Therapeutics
PeptiDream Inc is a privately-held biopharmaceutical company employing
our proprietary Random Peptide Integrated Discovery (RAPID) Platform,
a state-of-the-art highly versatile peptide generation and selection platform
which enables the production of highly diverse non-standard peptide libraries
with high efficiency, for the discovery and development of best-in-class and
first-in-class peptide-based therapeutics.
PeptiDream aspires to be a world leader in the discovery and development
of novel highly functional peptide therapeutics to address unmet medical
needs and improve the quality of life of patients worldwide.
Established in 2006
http://www.peptidream.com/index.html
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
Advanced Softmaterials Co.,Ltd
Established in 2005
CEO & Presiden Yutaka Hara
http://www.asmi.jp/
物理架橋
化学架橋
微結晶
架橋
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
滑車効果
Challenges of university-industry collaborations in Japan
• Less marketing-oriented intellectual property head office of
university・TLO
Lessons from the US cases =
Repetition of administrative model, legal model and marketing model
• Weak collaboration between the intellectual property head
office of university and TLO
Realization of rights =
Intellectual property head office and marketing = TLO are the worst model
• Use of human resources and development
• Unclear evaluation indicators of university-industry collaborations
• Increase in the number of universities that assign patents
to patent aggregators
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
Challenges of university-industry collaborations in industries
• Strength in the principle of company’s own
development
NIH syndrome
Not changed without changing personnel evaluation system
• Slow decision making and lack of challenging
spirit
Words of Rita Nelson of MIT
• Lack of development-type ventures
• Companies having partnership with patent trolls
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
Human Resource Development and Networking
through Inter-university Cooperation
UNITT 2011 Annual Conference in Japan.
* UNITT = University Network for Innovation & Technology Transfer
（AUTM Japan)
8th UNITT Annual Conference was held at Doshisha University on September 9th &
10th.
(Over 500 people attended to last conference )
Technology Transfer educational courses (Basic and Applied Courses) are
provided by UNITT.
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）
Let us promote the concept of the right
technology in the right place to achieve
a technology-oriented nation in a
brighter new era.
“Integrating knowledge and
contributing to the society.”
Thank you!
ＴＯＤＡＩＴＬＯ（TLO for the Univ. of Tokyo）

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