Antiepileptic Drugs Market

Antiepileptic Drugs Market – Size, Share, Outlook,
and Opportunity Analysis, 2018 – 2026
Epilepsy is associated with disrupted activities in the brain called seizures, which affects the
central nervous system. Epilepsy is categorized into generalized seizures and partial seizures
based on the areas affected in the brain. Generalized seizures affect the whole brain, while
partial seizures affect just one part of the brain. Seizures are further classified into mild seizures
and stronger seizures depending on the severity of the seizures. The diagnosis of mild seizures
are difficult, as its lasts only for few seconds. Stronger seizures may last for a few seconds to
several minutes, resulting in spasms and uncontrollable muscle twitches. This may cause the
patient to lose consciousness, lead to temporary loss of cognition, or memory loss during the
seizure. Epilepsy occurring due to brain infections such as meningitis is known as symptomatic
epilepsy, while genetics related condition is called idiopathic epilepsy.
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The number of available antiepilepsy drugs have doubled over the past few decades and for the
treatment of pediatric epilepsy, nine new drugs were launched in the last decade, as the
benefits of the medicines are greater than the subsequent side-effects from the medicine. Third
generation epilepsy drugs are rapidly replacing second and first generation drugs, as they are
more safe and tolerable than the previous generation drugs. Few first generation drugs are
Phenytoin (Dilantin and Phenytek), Carbamazepine (Carbatrol), Valproate (Depakote),
Oxycarbazepine (Trileptal), Phenobarbital (Luminal), Primidone (Mysoline); and second
generation drugs are Lamotrigine (Lamictal), Pregabalin (Lyrica), Lacosamide (Vimpat), and
Rufinamide (Banzel/Inovelon). The newer drugs have better efficacy, with much better
pharmacokinetic profiles and fewer drug interactions than the classic first generation drugs. For
instance, the third generation drugs, UCB’s Keppra (levetiracetam) and GlaxoSmithKline’s
(GSK’s) Lamictal (lamotrigine) have rapidly become the commonly used drugs for first-line
treatments.
Report includes chapters which deeply display the following deliverable about industry :
• Antiepileptic Drugs Market Research Objective and Assumption
• Antiepileptic Drugs Market Purview - Report Description, Executive Summary, and Coherent
Opportunity Map (COM)
• Antiepileptic Drugs Market Dynamics, Regulations, and Trends Analysis - Market Dynamics,
Regulatory Scenario, Industry Trend, Merger and Acquisitions, New system Launch/Approvals,
Value Chain Analysis, Porter’s Analysis, and PEST Analysis
• Global Antiepileptic Drugs Market, By Regions
• Antiepileptic Drugs Market Competition by Manufacturers including Production, Share,
Revenue, Average Price, Manufacturing Base Distribution, Sales Area and Product Type.
• Antiepileptic Drugs Market Manufacturers Profiles/Analysis including Company Basic
Information, Manufacturing Base and Its Competitors.
• Antiepileptic Drugs Market Manufacturing Cost Analysis including Key Raw Materials and Key
Suppliers of Raw Materials.
• Industrial Chain, Sourcing Strategy and Downstream Buyers including Upstream Raw Materials
Sourcing and Downstream Buyers
• Marketing Strategy Analysis, Distributors/Traders including Marketing Channel, Market
Positioning and Distributors/Traders List.
• Market Effect Factors Analysis including Technology Progress/Risk, Consumer Needs/Customer
Preference Change and Economic/Political Environmental Change.
• Antiepileptic Drugs Market Forecast including Production, Consumption, Import and Export
Forecast by Type, Applications and Region.
• Research Findings and Conclusion
Antiepileptic Drugs Market Drivers
Factors such as rising prevalence of epilepsy and robust pipeline are expected to boost the
market growth over the forecast period. According to the study by Epilepsy Action Australia
statistics in 2017, around 50 million people globally have epilepsy with around 80% of the
people living in emerging economies such as India, Brazil, and China. Moreover, according to
the Centers for Disease Control and Prevention, in 2017, an estimated 3.4 million people have
active epilepsy in the U.S., which includes 3 million adults and 470,000 children. Manufacturers
have potential drug molecules in the pipeline for the treatment of various forms of epilepsy. For
instance, SK Life Sciences, Inc. has Cenobamate (YKP3089) in Phase 3 clinical trials. Eisai, Co.,
Ltd. has the drug Perampanel in Phase 2 clinical trials, and Marinus Pharmaceuticals, Inc. has
the drug Ganaxolone in Phase II clinical trials. The expected launches of these drugs over the
forecast period is expected to create favorable condition for the market growth. Moreover, in
2015, Neurelis, Inc. received orphan drug designation for NRL-1 for the treatment of acute
repetitive seizures and the drug is currently in phase III clinical trials. In 2016, Pfizer, Inc.’s
Lyrica (pregabalin) cleared phase-3 clinical trials for prescription to pediatric patients. Drug
launches by leading manufacturers is expected to foster growth of the antiepileptic drugs market
over the forecast period. For instance, in 2016, UCB Pharma Limited received the U.S. FDA
approval for Briviact, for the treatment of patients with partial onset seizures. Mylan launched
generic Felbatol tablets in the U.S. after receiving approval from the U.S. Food & Drug
Administration in 2016. These factors are expected to boost the market growth over the forecast
period.
However, mild neurological adverse effects shown by these drugs can be fatal and the adverse
reactions and risks vary with each medication, which is expected to hamper the adoption rate
of the antiepileptic drugs over the forecast period, in turn affecting the market growth.
Antiepileptic Drugs Market Regional Analysis
North America and Europe are expected to witness significant growth in the market over the
forecast period due to robust pipeline for epilepsy treatment and individual efforts by leading
manufacturers. For instance, Pfizer, Inc. entered into partnership with Epilepsy Foundation to
find solutions for generic forms of epilepsy and associated neurological disorders in 2014. Asia
Pacific region is expected to show positive developments over the forecast period, owing to
drug launches by leading manufacturers in the region. For instance, UCB Pharma received
approval in Japan for Vimpat adjunctive therapy for partial onset seizures of epilepsy in 2016.
Moreover, Eisai Pharma launched antiepilepsy drug Fycompa in India in 2017.
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Antiepileptic Drugs Market Competitive Landscape
Key players operating in the global antiepileptic drugs market include GlaxoSmithKline plc,
Johnson & Johnson, Valeant Pharmaceuticals International, Inc., Abbott Laboratories, Cephalon,
Inc., Pfizer, Inc., Sunovion Pharmaceuticals, Inc., Novartis AG, UCB Pharma Ltd., and Sanofi
S.A.
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Epilepsy is associated with disrupted activities in the brain called seizures, which affects the central nervous system.

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